CN102283978B - Traditional Chinese medicine for treating chronic rhinitis - Google Patents
Traditional Chinese medicine for treating chronic rhinitis Download PDFInfo
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- CN102283978B CN102283978B CN 201110251483 CN201110251483A CN102283978B CN 102283978 B CN102283978 B CN 102283978B CN 201110251483 CN201110251483 CN 201110251483 CN 201110251483 A CN201110251483 A CN 201110251483A CN 102283978 B CN102283978 B CN 102283978B
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Abstract
The invention discloses a Chinese medicine for treating chronic rhinitis. The Chinese medicine is characterized by being prepared from the following raw materials in parts by weight: 5-8 parts of honey-fried herba ephedrae, 8-10 parts of notopterygium root, 8-12 parts of mint, 8-12 parts of honeysuckle flower, 8-12 parts of weeping forsythiae, 8-12 parts of indigowoad root, 8-12 parts of biond magnolia flower, 25-35 parts of gypsum, 12-18 parts of dark plum fruit, 12-18 parts of flower of Chinese scholartree, 20 parts of Japan yam rhizome, 12-18 parts of cordate houttuynia and 8-12 parts of liquorice. According to the Chinese medicine disclosed by the invention, the efficacies of eliminating dampness, relieving pains, dredging veins, expelling wind and heat and clearing away heat and toxic material can be achieved; the aim of treating rhinitis can be achieved by treating the principal and secondary aspect of disease; and shown by clinical tests, the total effective rate of the Chinese medicine reaches 94.8 percent.
Description
Technical field
The present invention relates to the field of Chinese medicines, especially treat the Chinese medicine of rhinitis.
Background technology
Rhinitis is divided into acute rhinitis, chronic rhinitis.Acute rhinitis claims again cold nasal obstruction, and take nasal obstruction, sneeze, thin nasal discharge or mucus nasal mucus is cardinal symptom, by the nasal cavity inspection, shows as nasal mucosa hyperemia, and the nasal cavity secretions increase plays disease more anxious, and the course of disease is shorter.
Chronic rhinitis is the bronchia mucosal that causes because of factors such as whole body, part or occupational environment and the chronic inflammatory disease of Submucosa.Comprise two kinds of simple rhinitis and chronic hypertrophic rhinitiss.The former is alternately property and intermittence for nasal obstruction at clinical manifestation, and many tears, be often the mucus nasal mucus.The latter's clinical manifestation, for nasal obstruction is serious, mostly is persistence, and nasal mucus is few, more sticky, is difficult for blowing out etc.The pathological changes protracted course of disease, can have influence on olfactory function.
At present, the medicine for the treatment of chronic rhinitis mainly is divided into two classes, one class is medicine for external use, and for example spray or nasal drop, act on obvious in a short time, can not maintain long curative effect, easily recurrence after drug withdrawal, another kind of is oral medicine, this class medicine be take Chinese medicine as main, although for clinical, the situation of ubiquity unsatisfactory curative effect.
Summary of the invention
The present invention can not fundamentally effect a radical cure the problem of chronic rhinitis in order to solve current oral medicine, provides a kind of curative effect fast, the Chinese medicine of the treatment chronic rhinitis that cure rate is high.
For the problem that will solve, technical scheme of the present invention is: the Chinese medicine for the treatment of chronic rhinitis, by the Chinese medicine medicines compatibility, formed, a kind of Chinese medicine for the treatment of chronic rhinitis, it is characterized in that, be that the preparation of raw material by following weight portion proportioning becomes by each raw material of Chinese medicine: Herba Ephedrae (processed) 5-8, Rhizoma Et Radix Notopterygii 8-10, Herba Menthae 8-12, Flos Lonicerae 8-12, Fructus Forsythiae 8-12, Radix Isatidis 8-12, Flos Magnoliae 8-12, Gypsum Fibrosum 25-35, Fructus Mume 12-18, Flos Sophorae 12-18, Rhizoma Dioscoreae Nipponicae 20, Herba Houttuyniae 12-18, Radix Glycyrrhizae 8-12.
Preferred proportioning raw materials is:
Herba Ephedrae (processed) 6, Rhizoma Et Radix Notopterygii 9, Herba Menthae 10, Flos Lonicerae 9, Fructus Forsythiae 11, Radix Isatidis 9, Flos Magnoliae 11, Gypsum Fibrosum 27, Fructus Mume 15, Flos Sophorae 16, Rhizoma Dioscoreae Nipponicae 20, Herba Houttuyniae 14, Radix Glycyrrhizae 11.
This formula has wind and heat dispersing, heat-clearing toxin-expelling functions, and the pharmacological action of its Chinese medicine is as follows, as: Herba Menthae: Pulvis Diaphoreticus gas, pathogenic wind expelling detumescence; Flos Magnoliae: dispel the wind, sensible; Flos Lonicerae: heat-clearing and toxic substances removing, antibiotic; Herba Houttuyniae is heat and toxic materials clearing away medicine, suppresses the pathogen growth of focus, strengthens leukocytic phagocytic function, can also improve the vigor of lysozyme in patients serum and body fluid, accelerates the reparation of nose focus; Rhizoma Dioscoreae Nipponicae: relieve the pain; Herba Ephedrae (processed): the effect of dispersing wind-cold, can treat that the nasal obstruction of stuffy nose (chronic rhinitis) is obstructed or watery nasal discharge is more than; Rhizoma Et Radix Notopterygii: analgesic, antiinflammatory action.
The present invention can reach dry, the effect of pain relieving, sensible, wind and heat dispersing, heat-clearing and toxic substances removing, by treating both the principal and secondary aspects of a disease, reach the purpose for the treatment of rhinitis.
The method for preparing medicine of the present invention:
1, take raw material by above-mentioned weight ratio,
2, water cleans impurity, uses the non-metallic vessel splendid attire,
3, the room temperature rinsing is 2 times, and rinsing adopts washing
4, Gypsum Fibrosum is decocted, is decocted 40 minutes with the alcoholic solution of 70-85%,
5, by Herba Ephedrae (processed), Rhizoma Et Radix Notopterygii, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Flos Magnoliae, Fructus Mume, Flos Sophorae, Rhizoma Dioscoreae Nipponicae, Herba Houttuyniae, Radix Glycyrrhizae and after the Gypsum Fibrosum decoction liquor is mixed, with the alcoholic solution of 70-85%, decocted, a 40-50 minute,
6, be concentrated into paste after decocting three times, with the Flos Magnoliae of pulverizing, Herba Menthae raw material, be mixed in making sheet and naturally dry,
7,, after drying, with pulverizer, pulverize,
8, with 120 orders, sieve, ultraviolet virus killing, incapsulate, each capsule 0.5 gram medicated powder of packing into.
In step 4 and step 5, the concentration of ethanol is preferably 80%.
The present invention is as follows through the clinical comparison result of the test:
Treatment group is chosen 231 routine patients and is taken medicine of the present invention, and matched group 100 examples are taken HUODAN WAN, and two groups of cases, at aspects such as sex, age, the course of disease, ill-distributions, are learned and processed no significant difference by statistics, and comparability (in Table 1) is arranged
Table 1 liang group sex, mean age, average course of disease situation are relatively
Annotate: compare P between group
all>0.05
Therapeutic Method
One, observation index
(1) safety indexes: routine blood test, routine urinalysis, stool routine examination, electrocardiogram, liver function, renal function
(2) health giving quality index: main clinic symptoms and sign: have a stuffy nose, flow turbid tears, olfactory disorder, headache, heating, nasal mucosa swelling, picture of the tongue, pulse condition etc.
Two, efficacy assessment standard
Recovery from illness: symptom all disappears, and the nasal cavity inspection is normal
Produce effects: nasal obstruction, watery nasal discharge transference cure or obviously improvement, nasal cavity inspection sign is obviously improved.
Effectively: nasal obstruction, watery nasal discharge sx↓, local sign is improved.
Invalid: sings and symptoms is not improved.
Three, medication
According to case inclusive criteria in " new Chinese medicine treatment acute and chronic nasal sinusitis guideline of clinical investigations ", include in and observe the first medicine of inactive other treatment rhinitis of case, be divided into treatment group and matched group.
Treatment group and matched group are taken respectively medicine of the present invention and HUODAN WAN:
Treatment group: 2 times on the one, 4 capsules that adopt embodiment 4 to make, warm water delivery service, 28 days each courses for the treatment of.
Matched group: 6 grams, 2 times on the one, warm water delivery service, 28 days each courses for the treatment of.
Therapeutic outcome
Treat two courses for the treatment of, 28 days each courses for the treatment of, treatment group is cured 147 examples (63.6%), produce effects 46 examples (19.9%), and effective 26 examples (11.3%), invalid 12 examples (5.2%), total effective rate reaches 94.8%; Matched group is cured 21 examples (21%), produce effects 17 examples (17%), effective 40 examples (40%), invalid 22 examples (22%), total effective rate reaches 78% efficacy result in Table 2, and the medication effect that other embodiment make is the therapeutic test no significant difference therewith.
The table 2 liang clinical total effects of group treatment chronic rhinitis is (X relatively
2)
The specific embodiment
Below provide the embodiment of the indefiniteness of Chinese medicine composition prepared in accordance with the present invention.
Embodiment 1
1, press row weight portion proportioning and take raw material:
Preferential medical material, by weight ratio: Herba Ephedrae (processed) 5, Rhizoma Et Radix Notopterygii 9, Herba Menthae 10, Flos Lonicerae 10, Fructus Forsythiae 10, Radix Isatidis 10, Flos Magnoliae 10, Gypsum Fibrosum 30, Fructus Mume 15, Flos Sophorae 15, Rhizoma Dioscoreae Nipponicae 20, Herba Houttuyniae 15, Radix Glycyrrhizae 10.
2, removal of contamination, use the non-metallic vessel splendid attire,
3, the room temperature rinsing is 2 times,
4, Gypsum Fibrosum is decocted, is decocted 40 minutes with the alcoholic solution of 70-85%,
5, by Herba Ephedrae (processed), Rhizoma Et Radix Notopterygii, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Flos Magnoliae, Fructus Mume, Flos Sophorae, Rhizoma Dioscoreae Nipponicae, Herba Houttuyniae, Radix Glycyrrhizae and after the Gypsum Fibrosum decoction liquor is mixed, with the alcoholic solution of 70-85%, decocted, a 40-50 minute,
6, decoct the clear paste that is concentrated to relative density 1.1～1.2 after three times, with the Flos Magnoliae of pulverizing, Herba Menthae raw material, be mixed in making sheet and naturally dry,
7,, after drying, with pulverizer, pulverize,
8, with 120 orders, sieve, ultraviolet virus killing, incapsulate, each capsule 0.5 gram medicated powder of packing into.
Embodiment 2
Press row weight portion proportioning and take raw material:
Be by weight ratio: Herba Ephedrae (processed) 7, Rhizoma Et Radix Notopterygii 10, Herba Menthae 8, Flos Lonicerae 12, Fructus Forsythiae 12, Radix Isatidis 8, Flos Magnoliae 8, Gypsum Fibrosum 35, Fructus Mume 18, Flos Sophorae 18, Rhizoma Dioscoreae Nipponicae 20, Herba Houttuyniae 18, Radix Glycyrrhizae 12.
The residue preparation process is with embodiment 1.
Embodiment 3
Press row weight portion proportioning and take raw material:
Be by weight ratio: Herba Ephedrae (processed) 8, Rhizoma Et Radix Notopterygii 8, Herba Menthae 12, Flos Lonicerae 8, Fructus Forsythiae 10, Radix Isatidis 12, Flos Magnoliae 12, Gypsum Fibrosum 25, Fructus Mume 12, Flos Sophorae 12, Rhizoma Dioscoreae Nipponicae 20, Herba Houttuyniae 12, Radix Glycyrrhizae 8.
The residue preparation process is with embodiment 1.
Embodiment 4
Press row weight portion proportioning and take raw material:
Herba Ephedrae (processed) 6, Rhizoma Et Radix Notopterygii 9, Herba Menthae 10, Flos Lonicerae 9, Fructus Forsythiae 11, Radix Isatidis 9, Flos Magnoliae 11, Gypsum Fibrosum 27, Fructus Mume 15, Flos Sophorae 16, Rhizoma Dioscoreae Nipponicae 20, Herba Houttuyniae 14, Radix Glycyrrhizae 11.
The residue preparation process is with embodiment 1.
Claims (1)
1. a Chinese medicine for the treatment of chronic rhinitis, is characterized in that, each raw material of Chinese medicine, by following weight portion, consists of:
It is characterized in that, formed by following weight portion by each raw material of Chinese medicine:
Herba Ephedrae (processed) 6, Rhizoma Et Radix Notopterygii 9, Herba Menthae 10, Flos Lonicerae 9, Fructus Forsythiae l1, Radix Isatidis 9, Flos Magnoliae 11, Gypsum Fibrosum 27, Fructus Mume 15, Flos Sophorae 16, Rhizoma Dioscoreae Nipponicae 20, Herba Houttuyniae 14, Radix Glycyrrhizae 11.
(1) press row weight portion proportioning and take raw material:
Herba Ephedrae (processed) 6, Rhizoma Et Radix Notopterygii 9, Herba Menthae 10, Flos Lonicerae 9, Fructus Forsythiae 11, Radix Isatidis 9, Flos Magnoliae 11, Gypsum Fibrosum 27, Fructus Mume 15, Flos Sophorae 16, Rhizoma Dioscoreae Nipponicae 20, Herba Houttuyniae 14, Radix Glycyrrhizae 11,
(2) removal of contamination, use the non-metallic vessel splendid attire,
(3) the room temperature rinsing is 2 times,
(4) Gypsum Fibrosum is decocted, is decocted 40 minutes with the alcoholic solution of 70-85%,
(5) by Herba Ephedrae (processed), Rhizoma Et Radix Notopterygii, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Flos Magnoliae, Fructus Mume, Flos Sophorae, Rhizoma Dioscoreae Nipponicae, Herba Houttuyniae, Radix Glycyrrhizae and after the Gypsum Fibrosum decoction liquor is mixed, with the alcoholic solution of 70-85%, decocted, a 40-50 minute,
(6) decoct the clear paste that is concentrated to relative density 1.1～1.2 after three times, mix with the Flos Magnoliae of pulverizing, Herba Menthae raw material
In making sheet, naturally dry,
(7), after drying, with pulverizer, pulverize,
(8) with 120 orders, sieve, ultraviolet virus killing, incapsulate, each capsule 0.5 gram medicated powder of packing into.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110251483 CN102283978B (en) | 2011-08-30 | 2011-08-30 | Traditional Chinese medicine for treating chronic rhinitis |
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| CN 201110251483 CN102283978B (en) | 2011-08-30 | 2011-08-30 | Traditional Chinese medicine for treating chronic rhinitis |
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| CN102283978A CN102283978A (en) | 2011-12-21 |
| CN102283978B true CN102283978B (en) | 2013-12-25 |
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| CN105194505A (en) * | 2015-08-31 | 2015-12-30 | 颜海 | Traditional Chinese medicine for treating chronic rhinitis |
| CN105497486A (en) * | 2016-01-20 | 2016-04-20 | 赵世明 | Traditional Chinese medicine composition for treating chronic rhinitis |
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| CN1194752C (en) * | 2003-07-01 | 2005-03-30 | 河北以岭医药研究院有限公司 | Anti-virus Chinese medicine composition and preparation process thereof |
| CN101658585B (en) * | 2008-08-25 | 2012-04-18 | 北京以岭药业有限公司 | Application of Chinese medicinal composition in preparing medicament for treating nasosinusitis |
| CN101797299B (en) * | 2009-02-05 | 2013-03-27 | 北京以岭药业有限公司 | Refining method of traditional Chinese medicine composition water extract liquid containing fructus forsythiae |
| CN101491615A (en) * | 2009-02-25 | 2009-07-29 | 韩伯杨 | Medicine for treating rhinitis and its preparation method |
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