CN102274468B - Chinese medicinal composition for regulating female internal secretion and preparation method thereof - Google Patents

Chinese medicinal composition for regulating female internal secretion and preparation method thereof Download PDF

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CN102274468B
CN102274468B CN 201110249809 CN201110249809A CN102274468B CN 102274468 B CN102274468 B CN 102274468B CN 201110249809 CN201110249809 CN 201110249809 CN 201110249809 A CN201110249809 A CN 201110249809A CN 102274468 B CN102274468 B CN 102274468B
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radix
chinese medicine
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chinese medicinal
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CN102274468A (en
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李华
李进才
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Anhui Zhenhetang Pharmaceutical Co ltd
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HUBEI KANGJIN PHARMACEUTICAL CO Ltd
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Abstract

The invention discloses a Chinese medicinal composition for regulating female internal secretion. The Chinese medicinal composition comprises the following raw materials in parts by mass: 20-40 parts of astragalus, 10-20 parts of Chinese angelica, 10-20 parts of dangshen, 10-20 parts of szechuan lovage rhizome, 10-20 parts of epimedium herb, 10-20 parts of dahurian patrinia herb, 3-10 parts of liquoric root, 5-10 parts of turmeric root tuber, 5-15 parts of thinleaf milkwort rootbark and 3-10 parts of evodia fruit. HGH (Human Growth Hormone) active factors and antioxidase extracted from traditional Chinese medicinal materials such as astragalus, Chinese angelica, dangshen, szechuan lovage rhizome and the like with a modern process can be used for enhancing the cell viability of a human body, replenishing qi, nourishing blood, accelerating excretion of in-vivo metabolic waste, facilitating blood circulation and secretion of female ovary hormone and replenishing various amino acids, organized enzymes, minerals and trace elements needed by a human body, so that the internal secretion is effectively regulated, the blood circulation is conditioned comprehensively, the SOD (Superoxide Dismutase) activity is increased, the invasion of free radicals is effectively blocked, maintaining and protecting effects are achieved, and the effect of delaying aging is achieved.

Description

A kind of Chinese medicine composition of regulating female incretion and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition of regulating female incretion and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Research is found, women's youthful vigor and appearance skin are directly related with kidney, ovarian function and estrogen and androgen balance etc., 30~40 years old women because bear children, the burdens such as family and work cause health " loss of transfiniting ", make the balance of kidney, ovarian function and estrogen and androgen that variation occur, so senile symptom appears in a lot of people.This is because these variations have caused the overtired of some organ cells of human body, but this real aging that is not organ, the aging phenomenon that shows is a kind of " false aging " in fact, this section is generally about 5 years period.Further research is found, the aging in women this period can reverse, improve kidney, ovarian function and regulate the material of estrogen and androgen balance if can replenish in right amount, organ cell tired in the body is rejuvenated, the youth that the woman also will become.
Summary of the invention
Problem to be solved by this invention provides a kind of good effect, Chinese medicine composition of the adjusting female incretion that toxic and side effects is low and preparation method thereof.
Technical scheme provided by the invention is: a kind of Chinese medicine composition of regulating female incretion, according to the mass fraction, be that raw material makes by 20~40 parts of Radixs Astragali, 10~20 parts of Radix Angelicae Sinensis, 10~20 parts of Radix Codonopsis, 10~20 parts of Rhizoma Chuanxiongs, 10~20 parts of Herba Epimedii, 10~20 parts of Herba Patriniae, 3~10 portions of Radix Glycyrrhizaes, 5~10 portions of Radix Curcumaes, 5~15 parts of Radix Polygalaes and 3~10 parts of Fructus Evodiaes.The present invention also provides the preparation method of above-mentioned Chinese medicine composition: the Chinese crude drug Radix Astragali, Radix Angelicae Sinensis, Radix Codonopsis, Rhizoma Chuanxiong, Herba Epimedii, Herba Patriniae, Radix Glycyrrhizae, Radix Curcumae, Radix Polygalae and Fructus Evodiae are dropped in the extraction element, use water extraction, after extracting solution is concentrated, concentrated, dry, pulverize to such an extent that regulate the Chinese medicine composition of female incretion.
HGH active factors and antioxidase that the present invention uses modern crafts to extract from the Chinese crude drugs such as the Radix Astragali, Radix Angelicae Sinensis, Radix Codonopsis, Rhizoma Chuanxiong, can strengthen the human body cell vigor, benefiting qi and nourishing blood, accelerate the drainage of internal metabolism refuse, blood circulation promoting and the hormonal secretion of women's ovary, replenish each seed amino acid, organized enzyme, mineral, the trace element of needed by human body, thereby reach effective endocrine regulation, the comprehensively regulating blood circulation, improve SOD active, the effectively invasion and attack of blocking-up free radical, the maintenance economic benefits and social benefits, thus reach the effect of slow down aging.
The specific embodiment
Embodiment 1:
A kind of Chinese medicine composition of regulating female incretion according to the mass fraction, is that raw material makes by 20 parts of Radixs Astragali, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Codonopsis, 10 parts of Rhizoma Chuanxiongs, 10 parts of Herba Epimedii, 10 parts of Herba Patriniae, 3 portions of Radix Glycyrrhizaes, 5 portions of Radix Curcumaes, 5 parts of Radix Polygalaes and 3 parts of Fructus Evodiaes.
Preparation method: by said ratio, all Chinese crude drugs are dropped in the extraction pot, the water that adds ten times of amounts extracts 3 times, after extracting solution is concentrated, to concentrate extracting solution with ethanol again and carry out precipitate with ethanol, remove unnecessary impurity, left standstill 36 hours, then extract the good supernatant of precipitate with ethanol, concentrated, then dry, pulverizing.
Embodiment 2:
A kind of Chinese medicine composition of regulating female incretion, according to the mass fraction, be that raw material makes by 30 parts of Radixs Astragali, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Codonopsis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Herba Epimedii, 15 parts of Herba Patriniae, 6 portions of Radix Glycyrrhizaes, 10 portions of Radix Curcumaes, 10 parts of Radix Polygalaes and 6 parts of Fructus Evodiaes.
Preparation method: by said ratio, all Chinese crude drugs are dropped in the extraction pot, the water that adds ten times of amounts extracts 3 times, after extracting solution is concentrated, to concentrate extracting solution with ethanol again and carry out precipitate with ethanol, remove unnecessary impurity, left standstill 36 hours, then extract the good supernatant of precipitate with ethanol, concentrated, then dry, pulverizing.
Embodiment 3:
A kind of Chinese medicine composition of regulating female incretion, according to the mass fraction, be that raw material makes by 40 parts of Radixs Astragali, 20 parts of Radix Angelicae Sinensis, 20 parts of Radix Codonopsis, 20 parts of Rhizoma Chuanxiongs, 20 parts of Herba Epimedii, 20 parts of Herba Patriniae, 10 portions of Radix Glycyrrhizaes, 10 portions of Radix Curcumaes, 15 parts of Radix Polygalaes and 10 parts of Fructus Evodiaes.
Preparation method: by said ratio, all Chinese crude drugs are dropped in the extraction pot, the water that adds ten times of amounts extracts 3 times, after extracting solution is concentrated, to concentrate extracting solution with ethanol again and carry out precipitate with ethanol, remove unnecessary impurity, left standstill 36 hours, then extract the good supernatant of precipitate with ethanol, concentrated, then dry, pulverizing.
Embodiment 4:
A kind of Chinese medicine composition of regulating female incretion, according to the mass fraction, be that raw material makes by 30 parts of Radixs Astragali, 10 parts of Radix Angelicae Sinensis, 15 parts of Radix Codonopsis, 10 parts of Rhizoma Chuanxiongs, 15 parts of Herba Epimedii, 20 parts of Herba Patriniae, 8 portions of Radix Glycyrrhizaes, 10 portions of Radix Curcumaes, 10 parts of Radix Polygalaes and 18 parts of Fructus Evodiaes.
By said ratio, preparation method: by said ratio, all Chinese crude drugs are dropped in the extraction pot, add the water of ten times of amounts, extract 3 times, after extracting solution is concentrated, will have concentrated extracting solution with ethanol again and carry out precipitate with ethanol, remove unnecessary impurity, left standstill 36 hours, then extract the good supernatant of precipitate with ethanol, concentrated, then dry, pulverizing.
Embodiment 5: regulate the Chinese medicine capsules of female incretion, adopt conventional capsule production technology to make the product of embodiment 1-4: mix → granulate → fill → polishing, screening → bubble-cap → inner packing → outer package → check → warehouse-in.
The clinical practice example:
The gorgeous sex of name: Chen Hong: woman's age: 32 is facial withered and yellow, and pachylosis, black eye are obvious, taking the Chinese medicine of prescription of the present invention (one) after the course for the treatment of, (each 2, take continuously 1 month Chinese medicine capsules, every day 2 times.) complexion become ruddy, skin smooth is flexible, black eye disappear, the complete obiteration of former symptom.The index that female incretion is six changes as follows:
Follotropin (FSH) (3.8) mIU/ml before by treatment, (normal value is 5~40 mIU/ml) changes (7.2) mIU/ml after the treatment into, and (normal value is 5~40mIU/ml).
Interstitialcellstimulating hormone (ICSH) (LH) (41) mIU/ml before by treatment, (normal value is 5~25mIU/ml), changes (25) mIU/ml after the treatment into, and (normal value is 5~40mIU/ml).
(normal value is 0.23~0.91nmol/L) to (0.14) nmol/L before by treatment of prolactin antagonist (PRL), and (normal value is 0.23~0.91nmol/L) to change (0.31) nmol/L after the treatment into.
Estradiol (E2) by treatment before (37) picomole/liter (normal value be 48~521 picomoles/liter) in ovulation later stage, change (215) picomole in ovulation later stage after the treatment/liter (normal value be 48~521 picomoles/liter) into.
(normal value is 7.6~97.6nmol/L) to progesterone (P), and (normal value is 7.6~97.6nmol/L) to change (39.2) nmol/L that treats the rear ovulation later stage into by treatment (8.2) nmol/L in front ovulation later stage.
(normal value is 0.7~3.1nmol/L) to (0.52) nmol/L before by treatment of testosterone (T), and (normal value is 0.7~3.1nmol/L) to change (1.1) nmol/L after the treatment into.
Name: Wang Li sex: woman's age: 41 yellowish complexion lips are light, have a dizzy spell, and trick is unable, the anemia constipation, also be accompanied by gynaecopathia, taking the Chinese medicine of prescription of the present invention (two) after the course for the treatment of, (Chinese medicine capsules, every day 2 times, each 2, took continuously 2 months).Have a dizzy spell, the unable symptom complete obiteration of trick, facial wrinkles is unfolded and is shoaled, and the constipation Anemia is significantly improved, and the gynaecopathia symptom has also obtained very large alleviation.The index that female incretion is six changes as follows:
Follotropin (FSH) (4.08) mIU/ml before by treatment, (normal value is 5~40 mIU/ml) changes (26.5) mIU/ml after the treatment into, and (normal value is 5~40mIU/ml).
Interstitialcellstimulating hormone (ICSH) (LH) (39) mIU/ml before by treatment, (normal value is 5~25mIU/ml), changes (21) mIU/ml after the treatment into, and (normal value is 5~40mIU/ml).
(normal value is 0.23~0.91nmol/L) to (0.13) nmol/L before by treatment of prolactin antagonist (PRL), and (normal value is 0.23~0.91nmol/L) to change (0.26) nmol/L after the treatment into.
Estradiol (E2) by treatment before (101) picomole/liter (normal value be 48~521 picomoles/liter) in ovulation later stage, change (327) picomole in ovulation later stage after the treatment/liter (normal value be 48~521 picomoles/liter) into.
(normal value is 7.6~97.6nmol/L) to progesterone (P), and (normal value is 7.6~97.6nmol/L) to change (52.8) nmol/L that treats the rear ovulation later stage into by treatment (7.4) nmol/L in front ovulation later stage.
(normal value is 0.7~3.1nmol/L) to (0.5) nmol/L before by treatment of testosterone (T), and (normal value is 0.7~3.1nmol/L) to change (1.2) nmol/L after the treatment into.
Name: Qin Lin jasmine sex: woman's age: 36 endocrine disturbance, ovary decline, chest distress and palpitation symptoms, the symptoms such as menoxenia.Taking the Chinese medicine of prescription of the present invention (three) after the course for the treatment of, (each 2, took continuously 3 months Chinese medicine capsules, every day 2 times.) endocrine recovered normally, the ovarian activity cell improves greatly, and the smooth and easy menstruation of gaseous pulse also becomes normally, and it is moist that whole skin also becomes, and the chest distress and palpitation symptoms symptom is also cured.The index that female incretion is six changes as follows:
Follotropin (FSH) (3.6) mIU/ml before by treatment, (normal value is 5~40 mIU/ml) changes (26) mIU/ml after the treatment into, and (normal value is 5~40mIU/ml).
Interstitialcellstimulating hormone (ICSH) (LH) (3.2) mIU/ml before by treatment, (normal value is 5~25mIU/ml), changes (35) mIU/ml after the treatment into, and (normal value is 5~40mIU/ml).
(normal value is 0.23~0.91nmol/L) to (0.16) nmol/L before by treatment of prolactin antagonist (PRL), and (normal value is 0.08~0.92nmol/L) to change (0.37) nmol/L after the treatment into.
Estradiol (E2) by treatment before (39) picomole/liter (normal value be 48~521 picomoles/liter) in ovulation later stage, change (198) picomole in ovulation later stage after the treatment/liter (normal value be 48~521 picomoles/liter) into.
(normal value is 7.6~97.6nmol/L) to progesterone (P), and (normal value is 7.6~97.6nmol/L) to change (66) nmol/L that treats the rear ovulation later stage into by treatment (7.2) nmol/L in front ovulation later stage.
(normal value is 0.7~3.1nmol/L) to (0.6) nmol/L before by treatment of testosterone (T), and (normal value is 0.7~3.1nmol/L) to change (1.1) nmol/L after the treatment into.

Claims (3)

1. Chinese medicine composition of regulating female incretion, it is characterized in that: according to the mass fraction, be that raw material makes by 20~40 parts of Radixs Astragali, 10~20 parts of Radix Angelicae Sinensis, 10~20 parts of Radix Codonopsis, 10~20 parts of Rhizoma Chuanxiongs, 10~20 parts of Herba Epimedii, 10~20 parts of Herba Patriniae, 3~10 portions of Radix Glycyrrhizaes, 5~10 portions of Radix Curcumaes, 5~15 parts of Radix Polygalaes and 3~10 parts of Fructus Evodiaes.
2. a kind of Chinese medicine composition of regulating female incretion according to claim 1, it is characterized in that: according to the mass fraction, be that raw material makes by 30 parts of Radixs Astragali, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Codonopsis, 15 parts of Rhizoma Chuanxiongs, 15 parts of Herba Epimedii, 15 parts of Herba Patriniae, 6 portions of Radix Glycyrrhizaes, 10 portions of Radix Curcumaes, 10 parts of Radix Polygalaes and 6 parts of Fructus Evodiaes.
3. the preparation method of claim 1 or 2 described Chinese medicine compositions, it is characterized in that: the Chinese crude drug Radix Astragali, Radix Angelicae Sinensis, Radix Codonopsis, Rhizoma Chuanxiong, Herba Epimedii, Herba Patriniae, Radix Glycyrrhizae, Radix Curcumae, Radix Polygalae and Fructus Evodiae are dropped in the extraction element, use water extraction, after extracting solution is concentrated, concentrated, dry, pulverize to get Chinese medicine composition.
CN 201110249809 2011-08-29 2011-08-29 Chinese medicinal composition for regulating female internal secretion and preparation method thereof Expired - Fee Related CN102274468B (en)

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CN102008700A (en) * 2010-12-14 2011-04-13 句容市边城卫生院 Medicament for treating pelvic inflammation

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Publication number Priority date Publication date Assignee Title
CN102008700A (en) * 2010-12-14 2011-04-13 句容市边城卫生院 Medicament for treating pelvic inflammation

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Title
傅灵梅 *
等.尤昭玲教授论治多囊卵巢综合征经验述要.《中医药学刊》.2003,第21卷(第9期),1481,1528. *

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