CN102274458B - Bone setting powder and preparation method thereof - Google Patents
Bone setting powder and preparation method thereof Download PDFInfo
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- CN102274458B CN102274458B CN2011102128716A CN201110212871A CN102274458B CN 102274458 B CN102274458 B CN 102274458B CN 2011102128716 A CN2011102128716 A CN 2011102128716A CN 201110212871 A CN201110212871 A CN 201110212871A CN 102274458 B CN102274458 B CN 102274458B
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Abstract
The invention discloses a special-effect quick bone setting powder which is prepared from the following active pharmaceutical ingredients: 10-15g of angelica, 10-15g of frankincense, 5-10g of rhizoma sparganii, 5-10g of ground beetle, 5-10g of draconis sanguis, 10-20g of hippocampi, 5-10g of Rhizoma Zedoariae, 10-15g of costus root, 3-5g of Flos Caryophyllata, 6-10g of nard, 10-15g of sand ginger, 10-15g of notopterygium root and 10-15g of rhizoma corydalis. The bone setting powder disclosed by the invention is applicable to various fractures, including chronic old and comminuted fractures. All patients with good counterpoint and alignment can take the bone setting powder; and the bone setting powder has no toxic or side effect, and no adverse effect. The preparation method disclosed by the invention is simple and easy to implement, and ensures the full display of the active pharmaceutical ingredients in the aspect of pharmacology.
Description
Technical field
The present invention relates to a kind of bone knitting powder and preparation method thereof, belong to the Chinese materia medica technical field.
Background technology
Fracture is the traumatology department's commonly encountered diseases, frequently-occurring disease, and its characteristics state of an illness is anxious, and traumatic condition is heavy, processes or deals with improperly and can cause permanent disbility even life danger when it's too late.Tradition western medical treatment method is to be fixed as the master in the operative reduction, Traditional Chinese Medicine adds outer fixing with manual reduction.Usually need braking and lay up 60-90 days, namely as the rule of ancients described " 100 days injured in the sinews or bones " heal fractures, and the time is long, expense is high, brings the tremendous economic burden for patient's family and society.
Summary of the invention
The object of the present invention is to provide a kind of bone knitting powder that can help effective synthetism for fracture, bone injury.The present invention comprises cureless old and comminuted fracture mainly for all types of fracture, as long as para-position all can be taken the good person of line.Have no side effect and untoward reaction.
Can calculate time of union of fracture by clinical verification, generally ten days is a course for the treatment of, child 5-7 days, be grown up 10-15 days, and can recover normal, and greatly shorten treatment time, thereby alleviate patient's misery and financial burden in comminuted fracture 17-20 days.
Bone knitting powder of the present invention not only has magical curative effect to union of fracture, to the whole body degenerative osteoarthropathy, and the replenishing of infant calcium deficiency, the treatment of femur head necrosis obtains promising result equally.
Another object of the present invention is to provide the preparation method of above-mentioned bone knitting powder.Preparation method of the present invention is simple, and has guaranteed giving full play on the crude drug pharmacology.
For achieving the above object, the present invention adopts following technical scheme:
A kind of bone knitting powder, it is to be made by the crude drug of following weight portion proportioning: Radix Angelicae Sinensis 10-15g, Olibanum 10-15g, rhizoma sparganic 5-10g, Eupolyphaga Seu Steleophaga 5-10g, Sanguis Draxonis 5-10g, Hippocampus 10-20g, Rhizoma Curcumae 5-10g, Radix Aucklandiae 10-15g, Flos Caryophylli 3-5g, Radix Et Rhizoma Nardostachyos 6-10g, Rhizoma Kaempferiae 10-15g, Rhizoma Et Radix Notopterygii 10-15g, Rhizoma Corydalis 10-15g.
According to traditional Chinese medical science combination principle and modern pharmacology result of study, selecting above-mentioned 12 flavor Chinese crude drugs is crude drug of the present invention, and wherein the pharmacological action of every flavor medicine is as follows:
Radix Angelicae Sinensis-sweet, hot, warm.Return liver, the heart, spleen channel.The effect of invigorating blood circulation that having enriches blood.
Olibanum-bitter in the mouth is hot, and is warm in nature, nontoxic, can the blood-activating and qi-promoting pain relieving.
Rhizoma sparganic-bitter in the mouth, property is flat.The energy removing blood stasis, circulation of qi promoting, removing food stagnancy pain relieving.
Eupolyphaga Seu Steleophaga-salty in the mouth is cold in nature, and is slightly poisonous, energy promoting blood circulation to remove blood stasis, inducing menstruation to relieve menalgia.
Sanguis Draxonis-sweet, salty, property are flat.GUIXIN, liver, spleen channel.Has promoting blood circulation to remove blood stasis, analgesic therapy, the effect of hemostasia and promoting granulation.
Hippocampus-sweet in the mouth is warm in nature.Have the medicinal functions such as building body, kidney invigorating and YANG supporting, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic, tranquillizing and allaying excitement, relieving cough and asthma.
Rhizoma Curcumae-suffering, bitter, temperature.Return liver, spleen channel.Effect with removing blood stasis, promoting the circulation of QI to relieve pain.
The Radix Aucklandiae-acrid in the mouth is bitter, and is warm in nature.Return spleen, stomach, tripe, lung meridian.Have promoting the circulation of QI to relieve pain; The effect of intestinal stasis relieving in the accent.
Flos Caryophylli-property is hot, the flavor temperature.Enter lung, spleen, stomach, kidney four warps.Effect: warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.Cure mainly: control singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, ringworm.
Radix Et Rhizoma Nardostachyos-acrid in the mouth, sweet, warm.Return spleen, stomach warp.Have promoting the circulation of QI to relieve pain, the effect of relieving stagnation and activating the spleen.Be used for burnt QI stagnated by cold, incoordination between the spleen and stomach.
Rhizoma Kaempferiae-acrid in the mouth is warm in nature.Return the stomach warp.Have the circulation of qi promoting warming middle-JIAO, help digestion, the effect of pain relieving.
Rhizoma Et Radix Notopterygii-suffering, hardship, warm are returned bladder, liver, kidney channel, and hot temperature is bitter dry, and cold expelling wins wet, has dispersing wind-cold, the numbness relieving and pain relieving effect.
Rhizoma Corydalis-warm in nature, acrid in the mouth, hardship.Entering the heart, spleen, liver, lung meridian, is the quality goods of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, especially is world-famous for the effect of pain relieving.
The preparation method of bone knitting powder of the present invention, it comprises the steps:
(1) take by weighing by weight ratio Hippocampus, Radix Angelicae Sinensis, Olibanum, rhizoma sparganic, Rhizoma Curcumae, Eupolyphaga Seu Steleophaga, Sanguis Draxonis, clean drying, cutting in bulk or lamellar are fried, are baked take not blackening as degree at iron pan;
(2) take by weighing by weight ratio the Radix Aucklandiae, Flos Caryophylli, Radix Et Rhizoma Nardostachyos, Rhizoma Kaempferiae, Rhizoma Et Radix Notopterygii, Rhizoma Corydalis;
(3) step (1) and these crude drug of step (2) are ground into superfine powder, cross 120 mesh sieves;
(4) the medicated powder packing with step (3) preparation is finished product.The finished dosage forms of preparing is powder.
The combination of above-mentioned raw materials medicine can increase by corresponding proportion or reduce in process of production, as large-scale production can the kilogram or the ton be unit, small-scale production also can be in grams, and weight can increase or reduce, but the crude drug weight proportion constant rate between each component.
The using method of bone knitting powder of the present invention and points for attention:
Consumption: oral each four grams, every twice-daily, warm water delivery service, the child reduces by half, and calculates healing time by clinical practice, and ten days is a course for the treatment of, child 5-7 days, be grown up 10-15 days, comminuted fracture 17-20 days, fracture can connect.
Taboo item: take diet Herba Spinaciae during this showy reiolaena root-bark, drink tea, white turnip, Caulis et Folium Brassicae junceae, Semen phaseoli radiati and bean sprout, soybean product, vinegar, sauerkraut and Fructus Kaki.
Points for attention:
1. diet Oryza glutinosa and goods thereof after fracturing
2. fracture healing is prohibited sexual life in later six months
3. the fracture in patients with diabetes healing can prolong the course for the treatment of
4. this product was 3 years lower shelf-lifves of dry storage
Advantage of the present invention and innovative point are:
1) this medicine is mainly to all types of fracture, comprise cureless old and comminuted fracture after, as long as para-position, all can take the good person of line, the untoward reaction such as have no side effect.This product absorbs in human body and can improve microcirculation correction blood flow take for oral administration as main, and the formation of several amino acids and organic calcium, promotion bone collagen is provided, and calcium, phosphorus deposition make the sclerotin calcification, thereby reach the purpose of fast fracture-setting.
2) by clinical practice, calculate the synthetism time: 10 days is a course for the treatment of under normal circumstances, child 5-7 days, be grown up 10-15 days, and can recover normal in comminuted fracture 17-20 days.Generally speaking: no matter be which position fracture, must 60-90 talent can recover healing, use this medicine, needed to heal fully at fracture reduction in 15-20 days to lower of the good situation of line.Greatly shorten treatment time, it is said to have broken through ancients: the rule of 100 days treatment fracture.Reduce patient's misery and financial burden.
3) not only union of fracture there is magical effect according to clinical practice, to the whole body degenerative osteoarthropathy, the replenishing of infant calcium deficiency, satisfied effect is played in the treatment of femur head necrosis equally.
The specific embodiment
Medical material meets 2010 editions ministerial standards of Pharmacopoeia of People's Republic of China all available from Chinese Medicinal Materials Co.
Embodiment 1
1, prescription: Radix Angelicae Sinensis 10g, Olibanum 10g, rhizoma sparganic 5g, Eupolyphaga Seu Steleophaga 5g, Sanguis Draxonis 5g, Hippocampus 10g, Rhizoma Curcumae 5g, Radix Aucklandiae 10g, Flos Caryophylli 3g, Radix Et Rhizoma Nardostachyos 6g, Rhizoma Kaempferiae 10g, Rhizoma Et Radix Notopterygii 10g, Rhizoma Corydalis 10g.
2, preparation method:
(1) take by weighing by weight ratio Hippocampus, Radix Angelicae Sinensis, Olibanum, rhizoma sparganic, Rhizoma Curcumae, Eupolyphaga Seu Steleophaga, Sanguis Draxonis, clean drying, cutting in bulk or lamellar are fried, are baked take not blackening as degree at iron pan;
(2) take by weighing by weight ratio the Radix Aucklandiae, Flos Caryophylli, Radix Et Rhizoma Nardostachyos, Rhizoma Kaempferiae, Rhizoma Et Radix Notopterygii, Rhizoma Corydalis;
(3) step (1) and these crude drug of step (2) are ground into superfine powder, cross 120 mesh sieves;
(4) the medicated powder packing with step (3) preparation is finished product.
Embodiment 2
1, prescription: Radix Angelicae Sinensis 15g, Olibanum 15g, rhizoma sparganic 10g, Eupolyphaga Seu Steleophaga 10g, Sanguis Draxonis 10g, Hippocampus 20g, Rhizoma Curcumae 10g, Radix Aucklandiae 15g, Flos Caryophylli 5g, Radix Et Rhizoma Nardostachyos 10g, Rhizoma Kaempferiae 15g, Rhizoma Et Radix Notopterygii 15g, Rhizoma Corydalis 15g.
2, preparation method:
(1) take by weighing by weight ratio Hippocampus, Radix Angelicae Sinensis, Olibanum, rhizoma sparganic, Rhizoma Curcumae, Eupolyphaga Seu Steleophaga, Sanguis Draxonis, clean drying, cutting in bulk or lamellar are fried, are baked take not blackening as degree at iron pan;
(2) take by weighing by weight ratio the Radix Aucklandiae, Flos Caryophylli, Radix Et Rhizoma Nardostachyos, Rhizoma Kaempferiae, Rhizoma Et Radix Notopterygii, Rhizoma Corydalis;
(3) step (1) and these crude drug of step (2) are ground into superfine powder, cross 120 mesh sieves;
(4) the medicated powder packing with step (3) preparation is finished product.
Embodiment 3
1, prescription: Radix Angelicae Sinensis 12.5g, Olibanum 12.5g, rhizoma sparganic 7.5g, Eupolyphaga Seu Steleophaga 7.5g, Sanguis Draxonis 7.5g, Hippocampus 15g, Rhizoma Curcumae 7.5g, Radix Aucklandiae 12.5g, Flos Caryophylli 4g, Radix Et Rhizoma Nardostachyos 8g, Rhizoma Kaempferiae 12.5g, Rhizoma Et Radix Notopterygii 12.5g, Rhizoma Corydalis 12.5g.
2, preparation method:
(1) take by weighing by weight ratio Hippocampus, Radix Angelicae Sinensis, Olibanum, rhizoma sparganic, Rhizoma Curcumae, Eupolyphaga Seu Steleophaga, Sanguis Draxonis, clean drying, cutting in bulk or lamellar are fried, are baked take not blackening as degree at iron pan;
(2) take by weighing by weight ratio the Radix Aucklandiae, Flos Caryophylli, Radix Et Rhizoma Nardostachyos, Rhizoma Kaempferiae, Rhizoma Et Radix Notopterygii, Rhizoma Corydalis;
(3) step (1) and these crude drug of step (2) are ground into superfine powder, cross 120 mesh sieves;
(4) the medicated powder packing with step (3) preparation is finished product.
Application examples 1
Patient Lin Meiying, the woman, 76 years old, live door limit, Wenchang, Zhangzhou City, fall on May 23rd, 2006, went to Dong Pu commune hospital in ZhangZhou through X-ray right hand humerus end fracture on June 1, cause the humerus bar to separate with chi radius end and form a hole (about 1.5cm) when arm bending, this hole disappeared when arm stretched, the patient afterwards to the orthopaedics doctor of ZhangZhou institute of traditional Chinese medicine carry out fixing 20 days outward (because of patient's duodenum chronic ulcer housecoat vulnerary not) behind 20 days outer fixing, swollen do not disappear, pain is more than, after upon somebody's introduction, began to receive treatment July 1: give quick bone-setting powder, each bag, every day, secondary cooperated outer washing medicine, gave anti-inflammatory analgetic, suitably join and take a little vulnerary, changed dressings once in two days, 10 days is that the state of an illness takes an evident turn for the better after 10 days courses for the treatment of, and the swollen pain of moving back is ended, hands can be carried light thing, also can raise and pain not too, illustrate that bone has connected, the basic end for the treatment of on the 17th from July 1 to July.Explanation will strengthen taking exercise and outer washing medicine share, and makes meridians unobstructed, follows up a case by regular visits to the Spring Festival in 2007, and hands is the rehabilitation no sequel all, becomes a fine day and rains not bitterly.
Application examples 2
Patient Ye Rongji, woman, 70 years old, gorge, Nanping City sun Zhenjiang Jie Cun.Fall morning on October 4th, 1987 from being set forth in, through building the X-ray examination of doctor trained in Western medicine institute, avulsion fracture appears in the left side head of humerus.Local swelling is serious on inspection, obvious tenderness, and the left hand arm can not be raised and upper act, can only be lifted to 1/5th original places.External traumatic injury wound healing is loose after maneuver resets, quick bone-setting powder for oral administration and part vulnerary.In 87 year October 12 the Nikkei X-ray reset well, para-position is normal to line, can be lifted to originally 2/5ths, swelling alleviates, pain subtracts greatly, controls altogether afterwards 22 days.In check on October 30, the fracture full recovery is normal, and explanation continues to take good care of.
Application examples 3
Patient You Houjiong, the man, 3 years old, the Shunchang County haze was gone to the countryside and is connected the innovation village.Parent is told: infant is fallen in two days causes and is caused arthralgia, through building left side, joint, doctor trained in Western medicine institute X-ray left side bit slice (being numbered 891), examine and be left elbow distal humerus epicondyle oblique fracture, ulna far-end olecranon deflection medial displacement, the slightly broadening of left elbow joint gap, one, left elbow bone epicondylar fracture, two, the left dislocation of the elbow joint.Left elbow joint swelling was serious at that time.Namely with the manual reduction dislocation, the external plintlet is fixed, and changes dressings after three days, and quick bone-setting powder for oral administration merges vulnerary, is used in conjunction three days, once namely heals.
Application examples 4
The patient is dissolved thin treasured, the man, and 43 years old, the Shunchang intercounty can township's Nan Shan Village
Injured when going up a hill the lumbering work in December in 1987 17 days, December 3 Nikkeis are built doctor trained in Western medicine institute X-ray and are shown left side ectocondyle section spiral fracture, para-position is good to line, local medical treatment 12 days, still have no growth of spur, current situation section tenderness is obviously come medical, gives outer fixing, quick bone-setting powder 1 bag for oral administration, every day secondary, the traumatic injury wound healing is loose, each bag, every day secondary, successively medication three days, give simultaneously Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Cortex Acanthopancis, Radix Dipsaci, the Radix Astragali, Radix Glycyrrhizae 3 subsides according to the state of an illness, decocting is for oral administration, successively treats altogether four recoveries from illness.
Application examples 5
Patient Gao Pingxiu, the man, 13 years old, the Shunchang intercounty can township's Nan Shan Village
Fall in school the morning on August 5th, 1987, left hand lowerly first, at 3 in afternoon examines, and finds on inspection, left hand curves inwardly, and palpation is found 1/2nd places, left hand radius stage casing fracture, namely gives manual reduction, hear card wiping sound, fracture site connects, and para-position is good to line.Quick bone-setting powder for oral administration, each bag (4 gram) secondary every day, the external bone knitting powder adds vulnerary wrapping affected part, and is fixing outward with the fir hull clamping plate again, controls once, do not change dressings and heals.His grandmother was with him to treat at that time, because all being that inhabitation people in this town is familiar with mutually, ran into after 20 days, followed up a case by regular visits to child's state of an illness, and recovery from illness is not changed dressings again already, and was very fast good.
Application examples 6
Patient Wu Zhaobin, man, 47 years old, bright village, Shunchang County Yang Kou town
Patient main suit falls in the work of two weeks cause, accidentally through building doctor trained in Western medicine institute X-ray, right side the tenth fracture of rib gives quick bone-setting powder, each 1 bag (4 gram) secondary every day, give first three staggering amounts, it is loose to add the traumatic injury wound healing, each 1 bag (4 gram) secondary every day, three staggering amounts, and give prescriptions of Chinese medicine: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae Preparata, Olibanum, Myrrha, Rhizoma Corydalis, Fructus Aurantii, Radix Glycyrrhizae, serve on three subsides, decocting rushes medicated powder and controlled again afterwards in 3 days for oral administration, controls altogether three times by upper method, bone has connected as before, recovery from illness in successively ten days.
Application examples 7
Patient Wei state is emerging, man, 16 years old, the Xia Yang of Nanping City town
Far away by 1,2, the 3 bone old fractures in right side, quick bone-setting powder for oral administration are closed the traumatic injury wound healing and fallen apart, and cooperate prescriptions of Chinese medicine: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Radix Rehmanniae Preparata, Cortex Acanthopancis, Sanguis Gallus domesticus rise, are three doses more than the Radix Glycyrrhizae that decocting is for oral administration.In JIUYUE in 1988 further consultation on the 4th, after for the first time treatment, pain takes an evident turn for the better, and can the walking of lower ground take a walk, and method for the treatment of is the same.JIUYUE in 1988 X-ray check on the 10th, first, second and third bone basilar part fracture of right foot has callus formation, successively controls altogether ten days and recovers normal.
Application examples 8
Patient He Meimei, the woman grows up, hole Oleum Glycines factory under the Shunchang County great calendar town
Build the film making diagnosis of doctor trained in Western medicine institute in December 12 Nikkeis in 1987, the existing double fracture in tibiofibula far-end medial and lateral malleolus position, the fibula oblique fracture is embedded as the tibiofibula double fracture.In other clinic treatments, a lot of blisters of local appearance for preventing that sb.'s illness took a turn for the worse, cause periostitis before examining, and control fracture Gu control first surgery elimination blister again.Give quick bone-setting powder each 4 gram secondary warm boiled waters every day, successively control altogether recovery from illness in 18 days.
The above only is preferred embodiment of the present invention, and all equalizations of doing according to the present patent application claim change and modify, and all should belong to covering scope of the present invention.
Claims (2)
1. bone knitting powder, it is characterized in that: it is to be made by the crude drug of following weight portion proportioning: Radix Angelicae Sinensis 10-15g, Olibanum 10-15g, rhizoma sparganic 5-10g, Eupolyphaga Seu Steleophaga 5-10g, Sanguis Draxonis 5-10g, Hippocampus 10-20g, Rhizoma Curcumae 5-10g, Radix Aucklandiae 10-15g, Flos Caryophylli 3-5g, Radix Et Rhizoma Nardostachyos 6-10g, Rhizoma Kaempferiae 10-15g, Rhizoma Et Radix Notopterygii 10-15g, Rhizoma Corydalis 10-15g.
2. the preparation method of a bone knitting powder as claimed in claim 1 is characterized in that: comprise the steps:
(1) take by weighing by weight ratio Hippocampus, Radix Angelicae Sinensis, Olibanum, rhizoma sparganic, Rhizoma Curcumae, Eupolyphaga Seu Steleophaga, Sanguis Draxonis, clean drying, cutting in bulk or lamellar are fried, are baked take not blackening as degree at iron pan;
(2) take by weighing by weight ratio the Radix Aucklandiae, Flos Caryophylli, Radix Et Rhizoma Nardostachyos, Rhizoma Kaempferiae, Rhizoma Et Radix Notopterygii, Rhizoma Corydalis;
(3) step (1) and these crude drug of step (2) are ground into superfine powder, cross 120 mesh sieves;
(4) the medicated powder packing with step (3) preparation is finished product.
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| CN104383001A (en) * | 2014-12-08 | 2015-03-04 | 冯水庆 | Compound traditional Chinese medicine for setting broken bone and preparation method thereof |
| CN104524454A (en) * | 2014-12-22 | 2015-04-22 | 况喜才 | Tinospora sinensis pain-relieving tincture |
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| CN1146343A (en) * | 1995-09-25 | 1997-04-02 | 石建民 | External compress paste for discopathy |
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| CN1146343A (en) * | 1995-09-25 | 1997-04-02 | 石建民 | External compress paste for discopathy |
Non-Patent Citations (2)
| Title |
|---|
| 少林正骨精微生物限度检查方法验证试验;詹志红;《海峡药学》;20081015;第20卷(第10期);67-69 * |
| 詹志红.少林正骨精微生物限度检查方法验证试验.《海峡药学》.2008,第20卷(第10期),67-69. |
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