CN102274406B - Chinese medicinal composition for treating kidney stone - Google Patents

Chinese medicinal composition for treating kidney stone Download PDF

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CN102274406B
CN102274406B CN2011102325752A CN201110232575A CN102274406B CN 102274406 B CN102274406 B CN 102274406B CN 2011102325752 A CN2011102325752 A CN 2011102325752A CN 201110232575 A CN201110232575 A CN 201110232575A CN 102274406 B CN102274406 B CN 102274406B
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radix
chinese medicinal
calculus
chinese medicine
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CN102274406A (en
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于新娇
李常华
张伶俐
王河荣
康洁雪
连英姿
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Nantong Hongci Pharmaceutical Co Ltd
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于新娇
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Abstract

The invention aims to provide a Chinese medicinal composition for treating kidney stone with remarkable treatment effect and short treatment period. The Chinese medicinal composition is prepared by mixing the following Chinese medicinal raw materials in part by weight: 18 to 22 parts of dendrobium, 18 to 22 parts of desmodium, 18 to 22 parts of adenophora elata, 12 to 18 parts of pyrrosia lingua,12 to 18 parts of chicken's gizzard-membrane, 18 to 22 parts of prepared rhizome of rehmannia, 12 to 18 parts of medlar, 8 to 12 parts of immature bitter orange, 12 to 18 parts of atractylodes lancea, 8 to 12 parts of phellodendron, 12 to 18 parts of dwarf lilyturf tuber, 12 to 18 parts of figwort root, 12 to 18 parts of twotooth achyranthes, 28 to 32 parts of the root of kudzu vine and 18 to 22 parts of clematis root. The Chinese medicinal composition can effectively improve the discharge rate of stone, reduce discharge time of stone and improve clinic symptoms and positive signs, is safe and effective in clinical use, free from toxic and side effects and effective for treating kidney stone and has a high clinic use value.

Description

A kind of Chinese medicine composition for the treatment of renal calculus
Technical field
The invention belongs to technical field of Chinese medicines, specifically refer to a kind of Chinese medicine composition for the treatment of renal calculus.
Background technology
Renal calculus refers to betide the calculus of renal calices, renal pelvis and renal pelvis and ureter connecting portion.Majority is positioned at the renal pelvis renal calices, and excess of the kidney matter calculus is rare.Plain film shows that there are the fine and close shadow of single or multiple circles, oval or obtuse triangle, high and uniform density in the kidney district.How smooth the edge is, but the rough Fructus Mori shape that is is also arranged.Kidney is the lithogenous main position of urinary system shape, the calculus at other any positions can be primary in kidney, ureteral calculus is almost all from kidney, and renal calculus is than the easier coup injury kidney of other any position calculus, so early diagnosis and therapy is extremely important.
The treatment of renal calculus only has broken, molten, row, anti-four combinations, just can obtain satisfied clinical therapeutic efficacy.The treatment of renal calculus is not before having the external stone crushing appearance, for some relatively more difficult cases, the operation methods that adopt solve more, yet operation has increased financial burden for the patient, also increased the weight of the damage of body, the patient fair to some renal functioies particularly, the cicatrix at operative incision position is the good hotbed that calculus generates.Some that produce in the operation are sewed up the end of a thread, and also easily calculus generates.Although surgical calculus removing has such-and-such all drawbacks, and is bad to some renal functioies, or acute obstruction or pyogenic infection person are arranged, operation is again to save the irreplaceable method of life.Surgical calculus removing many times can't once be got again only.Traditional Chinese medical science calculus therapy can change the internal environment of human body, gets rid of the noxious substance that produces calculus in the blood, removes the material base that it produces calculus.Than maximum size can make it to dissolve, fragmentation diminishes and excretes.After removing vivotoxin, owing to purified organismic internal environment, again generation and the appearance of calculus have effectively been prevented.
Summary of the invention
The purpose of this invention is to provide that a kind of therapeutic effect is good, the Chinese medicine composition of the treatment renal calculus of short treating period.
For realizing above-mentioned technical purpose, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of renal calculus, it is characterized in that this Chinese medicine composition is to adopt the raw material Chinese medicine composition of following weight proportion to form: Herba Dendrobii 18-22, Herba Lysimachiae 18-22, Radix Adenophorae (Radix Glehniae) 18-22, Folium Pyrrosiae 12-18, Endothelium Corneum Gigeriae Galli 12-18, Radix Rehmanniae Preparata 18-22, Fructus Lycii 12-18, Fructus Aurantii Immaturus 8-12, Rhizoma Atractylodis 12-18, Cortex Phellodendri 8-12, Radix Ophiopogonis 12-18, Radix Scrophulariae 12-18, Radix Achyranthis Bidentatae 12-18, Radix Puerariae 28-32, Radix Clematidis 18-22.
The instructions of taking of Chinese medicine composition provided by the present invention is: after the material medicine of above-mentioned weight proportion is mixed, get its medicine juice according to the method for the fried Chinese medicine of tradition, every secondary 200-300ml minute takes for twice sooner or later, every day one pair.Period in a medicine, patient should note increasing drinking water, does activity more, so that calculus is conducive to discharge.
Raw material Chinese medicine in the above-mentioned Chinese medicine composition:
Herba Dendrobii is slightly cold, sweet, returns stomach, kidney channel.Has reinforcing stomach reg fluid, the effect of nourishing YIN and clearing away heat.
Herba Lysimachiae, sweet in the mouth, little hardship, cool in nature, return liver, gallbladder, kidney, urinary bladder channel.Can relieving stranguria by diuresis, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.
Radix Adenophorae (Radix Glehniae), sweet, cold.Can nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.,
Folium Pyrrosiae, sweet, bitter, be slightly cold, return lung, urinary bladder channel.Relieving stranguria by diuresis is arranged, the effect that lung heat clearing expels the heat-evil.
Endothelium Corneum Gigeriae Galli, sweet, cold, return spleen, stomach, small intestinal, urinary bladder channel.Promoting digestion and invigorating the stomach is arranged, the effect of arresting seminal emission.
Radix Rehmanniae Preparata, sweet, tepor is returned liver, kidney channel.The yin nourishing of enriching blood, the effect of life essence-filling, marrow-benefitting.
Fructus Lycii, sweet in the mouth, property are put down, and return Liver Channel, kidney channel, lung meridian.Can nourishing the liver, nourishing kidney, lung moistening.
Fructus Aurantii Immaturus, bitter, hot, cold, return spleen, stomach, liver, heart channel.Cure mainly stop in stagnant, the diseases such as feeling of fullness distending pain, constipation.
Rhizoma Atractylodis, hot, bitter, temperature is returned spleen, stomach, Liver Channel.Can be drying damp and strengthening spleen, expelling wind and cold makes eye bright.
Cortex Phellodendri, hardship, cold, return kidney, bladder, large intestine channel.Can heat clearing and damp drying, eliminating fire and detoxication.
Radix Ophiopogonis, sweet, little hardship is slightly cold, GUIXIN, lung, stomach warp.Can YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.
Radix Scrophulariae, sweet in the mouth, hardship, salty, cold nature is returned lung, stomach, kidney channel.Can clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.
Radix Achyranthis Bidentatae, liver, kidney channel are returned in bitter, acid, flat.Invigorating the liver and kidney is arranged, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, the effect of conducting blood to flow downwards.
Radix Puerariae, cool in nature, sweet in the mouth, suffering.Having induces sweat brings down a fever, and promotes the production of body fluid rash, the effect of yang invigorating antidiarrheal.
Radix Clematidis, hot salty, temperature, poisonous, enter urinary bladder channel.Has expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the merit of the loose hypochondriac lump.
The party has clearing away heat and promoting diuresis, Tonglin Paishi, tonifying speen and tonifying kidney, the effect of circulation of qi promoting softening the hard mass of holding concurrently.Wherein Endothelium Corneum Gigeriae Galli, Herba Lysimachiae, Folium Pyrrosiae can treating stranguria fossils, and wherein Herba Lysimachiae can increase ureteral action potential, and diuretic effect is arranged, and is conducive to promote ureteral calculus and moves down, the discharge of promotion calculus.Herba Dendrobii, Cortex Phellodendri, Radix Scrophulariae, Radix Puerariae clearing away heat and cooling blood, eliminating fire and detoxication, Radix Adenophorae (Radix Glehniae), Radix Rehmanniae Preparata, Fructus Lycii, Radix Ophiopogonis can YIN nourishing and the production of body fluid promoting, life essence-filling, marrow-benefitting, the Radix Clematidis expectorant addiction of fall apart, and it is descending that the cooperation Radix Achyranthis Bidentatae draws stone.All medicines share, and calculus is descending in energy tonifying speen and tonifying kidney, the promotion kidney, by increasing voided volume, accelerates ureteral peristalsis frequency, and calculus is discharged.
Below in conjunction with clinical practice Chinese medicine composition curative effect provided by the invention is done further checking.
Method: this group patient 50 examples, meet the renal calculus diagnostic criteria, be divided at random treatment group 30 examples, matched group 20 examples.Treatment group gives this Chinese medicine composition and takes treatment; Matched group gives the treatment of urinary calculi port clothes.Be one and a half months two groups of courses for the treatment of.Treatment fore-and-aft observing clinical symptoms, sign, calculus size, position, calculus are discharged the health giving quality indexs such as number, time and are changed; Electrocardiogram, liver function, the safety indexes such as renal function change.The result: 1. the treatment group total effective rate is 88%, is better than matched group (75%), but without notable statistics difference (P>0.05), shows that this traditional Chinese medicine composition for treating renal calculus has good therapeutic effect; Treatment group calculus discharge rate be 78% with matched group (52%) significant difference is relatively arranged, show that treatment group calculus discharge rate is higher than matched group; 3. treatment group calculus efflux time is 21.46 ± 11.76 days, with matched group (32.14 ± 12.88 days) significant difference (P<0.05) is arranged relatively, shows that treatment group calculus efflux time is significantly shorter than matched group; 4. diameter is more than or equal to the calculus of 0.6cm less than 1.0cm, the treatment group effective percentage is 95.5% with matched group (55.6%) significant difference (P<0.05) to be arranged relatively, shows that treatment group is better than matched group more than or equal to 0.6cm less than the calculus curative effect of 1.0cm for diameter; 5. the clinical symptoms sign total mark before and after treatment group and the treatment of control group all has significant difference (P<0.05), two components are poor significant difference (P<0.05), show that treatment group and matched group all can effectively improve renal calculus clinical symptoms and positive sign, the treatment group curative effect is better than matched group; 6. safety detects: blood, stool routine, liver function, renal function, the equal Non Apparent Abnormality of Electrocardiography change before and after two groups of treatments, show that this Chinese medicine composition is safe and effective, have no side effect.Conclusion: clinical observation shows: this traditional Chinese medicine composition for treating renal calculus has preferably therapeutic effect.This Chinese medicine composition energy Effective Raise calculus discharge rate shortens the calculus efflux time, improves clinical symptoms and positive sign, and clinical practice is safe and effective, has no side effect, and is a kind of effective ways for the treatment of renal calculus, and higher clinical value is arranged.
The specific embodiment
The invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind of Chinese medicine composition for the treatment of renal calculus, it is characterized in that this Chinese medicine composition is to adopt the raw material Chinese medicine composition of following weight proportion to form: Herba Dendrobii 20g, Herba Lysimachiae 20g, Radix Adenophorae (Radix Glehniae) 20g, Folium Pyrrosiae 15g, Endothelium Corneum Gigeriae Galli 15g, Radix Rehmanniae Preparata 20g, Fructus Lycii 15g, Fructus Aurantii Immaturus 10g, Rhizoma Atractylodis 15g, Cortex Phellodendri 10g, Radix Ophiopogonis 15g, Radix Scrophulariae 15g, Radix Achyranthis Bidentatae 15g, Radix Puerariae 30g, Radix Clematidis 20g.
Embodiment 2
A kind of Chinese medicine composition for the treatment of renal calculus, it is characterized in that this Chinese medicine composition is to adopt the raw material Chinese medicine composition of following weight proportion to form: Herba Dendrobii 18g, Herba Lysimachiae 22g, Radix Adenophorae (Radix Glehniae) 18g, Folium Pyrrosiae 18g, Endothelium Corneum Gigeriae Galli 12g, Radix Rehmanniae Preparata 22g, Fructus Lycii 12g, Fructus Aurantii Immaturus 12g, Rhizoma Atractylodis 12g, Cortex Phellodendri 12g, Radix Ophiopogonis 12g, Radix Scrophulariae 18g, Radix Achyranthis Bidentatae 12g, Radix Puerariae 32g, Radix Clematidis 18g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of renal calculus, it is characterized in that this Chinese medicine composition is to adopt the raw material Chinese medicine composition of following weight proportion to form: Herba Dendrobii 22g, Herba Lysimachiae 18g, Radix Adenophorae (Radix Glehniae) 22g, Folium Pyrrosiae 12g, Endothelium Corneum Gigeriae Galli 18g, Radix Rehmanniae Preparata 18g, Fructus Lycii 18g, Fructus Aurantii Immaturus 8g, Rhizoma Atractylodis 18g, Cortex Phellodendri 8g, Radix Ophiopogonis 18g, Radix Scrophulariae 12g, Radix Achyranthis Bidentatae 18g, Radix Puerariae 28g, Radix Clematidis 22g.

Claims (1)

1. Chinese medicine composition for the treatment of renal calculus, it is characterized in that this Chinese medicine composition is to adopt the raw material Chinese medicine composition of following weight proportion to form: Herba Dendrobii 18-22, Herba Lysimachiae 18-22, Radix Adenophorae (Radix Glehniae) 18-22, Folium Pyrrosiae 12-18, Endothelium Corneum Gigeriae Galli 12-18, Radix Rehmanniae Preparata 18-22, Fructus Lycii 12-18, Fructus Aurantii Immaturus 8-12, Rhizoma Atractylodis 12-18, Cortex Phellodendri 8-12, Radix Ophiopogonis 12-18, Radix Scrophulariae 12-18, Radix Achyranthis Bidentatae 12-18, Radix Puerariae 28-32, Radix Clematidis 18-22.
CN2011102325752A 2011-08-15 2011-08-15 Chinese medicinal composition for treating kidney stone Active CN102274406B (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1720945A (en) * 2005-06-28 2006-01-18 郑阿权 Medicine for treating calculus in urinary system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1720945A (en) * 2005-06-28 2006-01-18 郑阿权 Medicine for treating calculus in urinary system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
柯彤.中西医结合治疗尿路结石85例.《实用中医药杂志》.2005,第21卷(第10期),610-611. *

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