CN102258737A - Medicine for treating halitosis and preparation method thereof - Google Patents
Medicine for treating halitosis and preparation method thereof Download PDFInfo
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- CN102258737A CN102258737A CN201110191595XA CN201110191595A CN102258737A CN 102258737 A CN102258737 A CN 102258737A CN 201110191595X A CN201110191595X A CN 201110191595XA CN 201110191595 A CN201110191595 A CN 201110191595A CN 102258737 A CN102258737 A CN 102258737A
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- halitosis
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- radix angelicae
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- semen coicis
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Abstract
The invention belongs to the technical field of Chinese patent medicine, and in particular relates to a medicine for treating halitosis and a preparation method thereof. The invention mainly solves the problems that halitosis influences the face and image of people, and the medicines for treating halitosis only take temporary solution but can not effect a permanent cure. The medicine for treating halitosis provided by the invention is prepared from the following medicinal raw materials in parts by weight: 1-10 of clove, 3-15 of angelica, 3-15 of angelica sinensis, 3-15 of white gourd seed, 3-15 of chuanxiong rhizome, 3-15 of semen coicis and 3-15 of cardamon. The preparation method comprises the following steps of: mixing the clove, angelica, angelica sinensis, white gourd seed, chuanxiong rhizome, semen coicis and cardamon uniformly, pulverizing into medicinal powder of 80-120 meshes, encapsulating and disinfecting to obtain capsules. The medicine provided by the invention has good clinical curative effects on bad breath and halitosis, can effectively improve the condition of the oral cavity of a patient with halitosis, and has low cost and no toxic side effect.
Description
Technical field
The invention belongs to the Chinese Traditional Medicines technical field, be specifically related to a kind of fragrant mouthful medicine and preparation method thereof.
Background technology
Halitosis, halitosis are perplexing the mankind since ancient times always, bring very big worry for people's work and life, and according to the survey, the adult Chinese 10%~30% suffers from halitosis and halitosis.The traditional Chinese medical science thinks that many, the dyspepsias prosperous excessively by stomach-fire of halitosis, intestinal drying, stool are smooth, the aphtha stomatitis causes.Though halitosis is not really serious disease, but individual face and image problem.Also exist a lot of chewing gum, mouth sprays etc. to alleviate the medicine of halitosis in the market, but all cure the symptoms, not the disease, can not fundamentally solve problem of bad breath.
Summary of the invention
The present invention is primarily aimed at face and the image that halitosis influences people, and the medicine of treatment halitosis all is the problem of curing the symptoms, not the disease, and a kind of fragrant mouthful medicine that can treating both the principal and secondary aspects of a disease is provided.
The present invention also provides the preparation method of this perfume (or spice) mouth medicine.
Fragrant mouthful of medicine of the present invention is to be crude drug with following parts of medicines by weight:
Flos Caryophylli 1~10, the Radix Angelicae Dahuricae 3~15, Radix Angelicae Sinensis 3~15, Semen Benincasae 3~15, Rhizoma Chuanxiong 3~15, Semen Coicis 3~15, Fructus Amomi Rotundus 3~15.
Wherein the preferred proportioning of the present invention is:
Flos Caryophylli 4.5, the Radix Angelicae Dahuricae 6, Radix Angelicae Sinensis 6, Semen Benincasae 6, Rhizoma Chuanxiong 6, Semen Coicis 10, Fructus Amomi Rotundus 6.
Fragrant mouthful of medicine of the present invention can be made the dosage form on any pharmaceutics, as decoction, tablet, pill, powder, capsule, buccal tablet etc., and the present invention's capsule preferably wherein.
The preparation method of capsule of the present invention is as follows: with Flos Caryophylli, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Semen Benincasae, Rhizoma Chuanxiong, Semen Coicis, Fructus Amomi Rotundus mix homogeneously, be ground into 80~120 purpose medicated powder, in incapsulating, sterilization makes capsule.
Flos Caryophylli has intensive fragrance in the prescription of the present invention, and acrid in the mouth, warm in nature has the effect of reinforcing the kidney and supporting YANG, warming middle-JIAO to send down the adverse QI, is mainly used in stomachache, vomiting, singultus, disease such as suffer from abdominal pain, have loose bowels that treatment is caused by the cold-evil; The Radix Angelicae Dahuricae, has aromatic odor, acrid in the mouth, temperature, nontoxic, have antipyretic-antalgic, anti-inflammatory, antibacterial, blood pressure lowering hemostasis, activation sympathetic system hormone, suppress the effect of lipogenesis, the Radix Angelicae Dahuricae can also improve local blood circulation in addition, eliminate pigment and in tissue, excessively pile up, promote skin cell metabolism, and then reach the effect of tender white muscle skin; Radix Angelicae Sinensis, acrid in the mouth, sweet, warm in nature is returned liver, the heart, spleen channel, and having enriches blood invigorates blood circulation, the effect of menstruction regulating and pain relieving, loosening bowel to relieve constipation; Semen Benincasae, sweet in the mouth, cold in nature has removing heat from the lung and dissipating phlegm, evacuation of pus, makes us the effect of the good color in happy pool; Rhizoma Chuanxiong, acrid in the mouth, warm in nature is returned Liver Channel, has the effect of blood-activating and qi-promoting, wind-expelling pain-stopping; Semen Coicis, sweet in the mouth, light, cold nature is returned spleen, stomach, lung meridian, has the effect of promoting diuresis to eliminate damp pathogen, spleen invigorating, eliminating impediment, clearing away heat and discharging pus, is mainly used in diseases such as treatment edema, diarrhoea, cough due to lung-heat, rheumatalgia and weakness of the spleen and stomach; Fructus Amomi Rotundus, acrid in the mouth, warm in nature is returned spleen, stomach, lung meridian, has the effect of removing dampness, circulation of qi promoting, warming middle-JIAO, preventing or arresting vomiting.
Compatibility relationship wherein of the present invention is: the Flos Caryophylli fragrant odour, can control halitosis, reach on the Radix Angelicae Dahuricae fragrance, be monarch drug altogether; Fructus Amomi Rotundus, fragrant odour can be controlled halitosis, have be good for the stomach, facilitating digestion, orectic effect, be ministerial drug; Rhizoma Chuanxiong, fragrant odour, blood-activating and qi-promoting is ministerial drug; Radix Angelicae Sinensis, fragrant odour is enriched blood and is invigorated blood circulation, and is ministerial drug; Semen Coicis, promoting diuresis to eliminate damp pathogen, spleen invigorating is adjuvant drug; Semen Benincasae, clearing away heat-damp and promoting diuresis has the effect of beauty treatment concurrently, is adjuvant drug; All medicines share, and gather altogether and remove halitosis and halitosis, reach lips and teeth and give birth to purpose fragrant, breath freshening.
For further showing therapeutic effect of the present invention, the present invention has done following clinical verification:
The patient chooses:
In January, 2010 to 2010 year December 80 halitosis patients of picked at random in the department of Chinese medicine outpatient service of second Affiliated Hospital of Mountain Western Medicine S University, according to sex, age, the layering of state of an illness weight grade, each layer is divided into treatment group and matched group at random by the table of random number method more then, every group 40 example.
Diagnostic criteria:
Work out with reference to State Administration of Traditional Chinese Medicine's " traditional Chinese medical science disease diagnosis criterion of therapeutical effect ": 1. clinical cure: do not have halitosis and halitosis fully, and lips and teeth are given birth to fragrant, breath freshening; 2. clinical produce effects: do not have halitosis and halitosis fully; 3. clinical effective: halitosis and halitosis obviously alleviate; 4. clinical invalid: halitosis and halitosis do not have improvement.
Therapeutic Method:
Matched group: use mouth spraying agent, 6 times on the one, each 0.2 gram, spray after the meal; The treatment group: medicine of the present invention, every day three times, each 2, take after mixing it with water after the meal.
Therapeutic outcome
Treatment group and treatment of control group be after 6 months, treatment group, obvious effective rate 77.5%, effective percentage 15%, inefficiency 7.5%, total effective rate 92.5%; Matched group, obvious effective rate 55%, effective percentage 25%, inefficiency 20%, total effective rate 80%.Two groups of treatment efficacy results see Table 1.
Table 1: two groups of 6 months treatment efficacy results
Clinical observation shows in a word: medicine of the present invention has good and clinical curative effect for halitosis and halitosis, can effectively improve halitosis patient's oral condition, and cost low, have no side effect.
The specific embodiment
Embodiment 1
A kind of fragrant mouthful medicine, the medicine of getting with following weight is a crude drug:
4.5 kilograms of Flos Caryophyllis, 6 kilograms of the Radixs Angelicae Dahuricae, 6 kilograms of Radix Angelicae Sinensis, 6 kilograms of Semen Benincasaes, 6 kilograms of Rhizoma Chuanxiongs, 10 kilograms of Semen Coiciss, 6 kilograms of Fructus Amomi Rotunduss.
Concrete preparation method is as follows:
With Flos Caryophylli, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Semen Benincasae, Rhizoma Chuanxiong, Semen Coicis, Fructus Amomi Rotundus mix homogeneously, be ground into 80 purpose medicated powder, in the capsule of the 0.25g that packs into, sterilization makes capsule.
Instructions of taking: each 2, every day 3 times, continued to take 1~6 month.
Embodiment 2
A kind of fragrant mouthful medicine, the medicine of getting with following weight is a crude drug:
1 kilogram of Flos Caryophylli, 3 kilograms of the Radixs Angelicae Dahuricae, 3 kilograms of Radix Angelicae Sinensis, 3 kilograms of Semen Benincasaes, 3 kilograms of Rhizoma Chuanxiongs, 3 kilograms of Semen Coiciss, 3 kilograms of Fructus Amomi Rotunduss.
Concrete preparation method is as follows:
With Flos Caryophylli, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Semen Benincasae, Rhizoma Chuanxiong, Semen Coicis, Fructus Amomi Rotundus mix homogeneously, be ground into 100 purpose medicated powder, in the capsule of the 0.4g that packs into, sterilization makes capsule.
Instructions of taking: each 2, every day 3 times, continued to take 1~6 month.
Embodiment 3
A kind of fragrant mouthful medicine, the medicine of getting with following weight is a crude drug:
10 kilograms of Flos Caryophyllis, 15 kilograms of the Radixs Angelicae Dahuricae, 15 kilograms of Radix Angelicae Sinensis, 15 kilograms of Semen Benincasaes, 15 kilograms of Rhizoma Chuanxiongs, 15 kilograms of Semen Coiciss, 15 kilograms of Fructus Amomi Rotunduss.
Concrete preparation method is as follows:
With Flos Caryophylli, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Semen Benincasae, Rhizoma Chuanxiong, Semen Coicis, Fructus Amomi Rotundus mix homogeneously, be ground into 120 purpose medicated powder, in the capsule of the 0.5g that packs into, sterilization makes capsule.
Instructions of taking: each 2, every day 3 times, continued to take 1~6 month.
Claims (4)
1. fragrant mouthful of medicine is characterized in that with following parts of medicines by weight be crude drug:
Flos Caryophylli 1~10, the Radix Angelicae Dahuricae 3~15, Radix Angelicae Sinensis 3~15, Semen Benincasae 3~15, Rhizoma Chuanxiong 3~15, Semen Coicis 3~15, Fructus Amomi Rotundus 3~15.
2. fragrant mouthful of medicine is characterized in that with following parts of medicines by weight be crude drug:
Flos Caryophylli 4.5, the Radix Angelicae Dahuricae 6, Radix Angelicae Sinensis 6, Semen Benincasae 6, Rhizoma Chuanxiong 6, Semen Coicis 10, Fructus Amomi Rotundus 6.
3. fragrant mouthful medicine according to claim 1 and 2 is characterized in that described fragrant mouthful medicine is the dosage form on any pharmaceutics.
4. the preparation method of fragrant mouthful medicine according to claim 1 and 2 is characterized in that Flos Caryophylli, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Semen Benincasae, Rhizoma Chuanxiong, Semen Coicis, Fructus Amomi Rotundus mix homogeneously are ground into 80~120 purpose medicated powder, and in incapsulating, sterilization makes capsule.
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CN201110191595A CN102258737B (en) | 2011-07-11 | 2011-07-11 | Medicine for treating halitosis and preparation method thereof |
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CN102258737A true CN102258737A (en) | 2011-11-30 |
CN102258737B CN102258737B (en) | 2012-08-29 |
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Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1799633A (en) * | 2005-12-19 | 2006-07-12 | 侯治民 | Pure Chinese medicinal aromatic bag serial products and preparation method thereof |
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1799633A (en) * | 2005-12-19 | 2006-07-12 | 侯治民 | Pure Chinese medicinal aromatic bag serial products and preparation method thereof |
Non-Patent Citations (3)
Title |
---|
刘燕波等: "中草药在治疗口臭中的疗效", 《中华口腔医学研究杂志(电子版)》 * |
蔡滨成等: "中药五香丸治疗口臭120例", 《中医药学报》 * |
韩月红等: "口臭治验三则", 《中国民间疗法》 * |
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