CN102258554A - New medicine for treating senile dementia - Google Patents
New medicine for treating senile dementia Download PDFInfo
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- CN102258554A CN102258554A CN 201010185814 CN201010185814A CN102258554A CN 102258554 A CN102258554 A CN 102258554A CN 201010185814 CN201010185814 CN 201010185814 CN 201010185814 A CN201010185814 A CN 201010185814A CN 102258554 A CN102258554 A CN 102258554A
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- senile dementia
- new medicine
- new drug
- dementia
- treatment
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Abstract
The invention relates to a new medicine for treating the senile dementia. The new medicine is prepared from four active ingredients, namely musk ketone, beta-asarone, panax notoginseng saponins and icariin in a certain proportion; and the new medicine has special treatment effect on the senile dementia and the vascular dementia. The preparation formulation of the medicine can be solid preparation such as tablets, capsules, particles, pills and the like, and also can be liquid preparation such as oral liquid, emulsion, microemulsion and injection and the like.
Description
Technical field: the invention belongs to pharmaceutical sanitary field.
Background technology: alzheimer disease is human commonly encountered diseases, frequently-occurring disease, difficult disease, owing to environmental pollution, dietary structure is unreasonable and its sickness rate of multiple reason such as wound, disease is fast rise trend, has a strong impact on people's health and patient's dignity.But the treatment alzheimer disease never has ideal medicament, and the anti-treatment of alzheimer disease almost is in stage at a loss what to do.Development treatment alzheimer disease has become the urgent and great problem of medicine research and development.Along with going deep into of scientific research, people more and more clearly recognize alzheimer disease be old body particularly in the cerebral tissue multiple factor imbalance as: the blood supply in brain deficiency, big cerebral microcirculation disturbance, cerebral tissue cholinesterase activity are too high, cerebral tissue aluminum, lead, inflammatory factor level are too high, the cerebral tissue superoxide dismutase activity cross low etc. due to.The treatment alzheimer disease is not a target spot, the problem that ingredient can solve, and need take multicomponent, many target spots, multipath Comprehensive Treatment at etiology and pathogenesis.Chinese medicine has significant advantage and experience accumulation in this respect.But, the treatment alzheimer disease writes out a prescription in aspect defectives such as preparation technology, dosage form, drug loading, effective dose, compliances because need taking for a long time with traditional Chinese medicine, Chinese medicine is difficult to be not fully exerted in the curative effect aspect the treatment alzheimer disease, and the treatment advantage is not fully manifested.This research is exactly to start with from the experience prescription of the famous Traditional Chinese Medicine experts treatment of research excavation alzheimer disease, optimizes the Chinese medicine best prescription by pharmacology, pharmacodynamic study; Excellent through extracting purification, and then select " best compatibility " composition (component) and best proportion compatibility, and then " composition of medicine " of development treatment alzheimer disease.
At above problem, the novel anti senile dementia preparation that the present invention develops is fast at alzheimer disease Different types of etiopathogenises pathogenesis, determined curative effect, produce effects, lasting medicine, toxic and side effects are little, facilitate patients.
Concrete summary of the invention is as follows, and a kind of new drug for the treatment of senile dementia is characterized in that it comprises the following aspects:
(1) muscone, beta-Asarone, Radix Notoginseng total arasaponins, icariin are formed in this new drug.
(2) with the described drug ratios of claim (3) be: 0～2: 0～100: 0～300: 0～300.
(3) dosage form of this new drug is that this pharmaceutically dosage form is liquid preparations such as solid preparations such as tablet, capsule, granule, pill or oral liquid, mixture, Emulsion, microemulsion, injection.
(4) this new drug is mainly used in treatment alzheimer disease, vascular dementia and mixed type dementia.
Embodiment 1
Muscone, beta-Asarone, Radix Notoginseng total arasaponins, icariin ratio are: 1: 50: 100: 200, add suitable adjuvant, capsule.
Embodiment 2
Muscone, beta-Asarone, Radix Notoginseng total arasaponins, icariin ratio are: 1: 60: 200: 260, add suitable adjuvant, and make oral micro-emulsion.
Claims (1)
1. new drug for the treatment of senile dementia is characterized in that it comprises the following aspects:
(1) muscone, beta-Asarone, Radix Notoginseng total arasaponins, icariin are formed in this new drug.
(2) with the described drug ratios of claim (3) be: 0～2: 0～100: 0～300: 0～300.
(3) dosage form of this new drug is that this pharmaceutically dosage form is liquid preparations such as solid preparations such as tablet, capsule, granule, pill or oral liquid, mixture, Emulsion, microemulsion, injection.
(4) this new drug is mainly used in treatment alzheimer disease, vascular dementia and mixed type dementia.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010185814 CN102258554A (en) | 2010-05-28 | 2010-05-28 | New medicine for treating senile dementia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010185814 CN102258554A (en) | 2010-05-28 | 2010-05-28 | New medicine for treating senile dementia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102258554A true CN102258554A (en) | 2011-11-30 |
Family
ID=45005520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201010185814 Pending CN102258554A (en) | 2010-05-28 | 2010-05-28 | New medicine for treating senile dementia |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102258554A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110638823A (en) * | 2019-10-25 | 2020-01-03 | 贵州中医药大学 | Application of icariin in preparation of medicine for treating vascular dementia |
-
2010
- 2010-05-28 CN CN 201010185814 patent/CN102258554A/en active Pending
Non-Patent Citations (3)
| Title |
|---|
| 《中国优秀硕士学位论文全文数据库》 20061231 郑明 淫羊藿苷伍用三七总皂苷改善血管性痴呆大鼠空间学习记忆及抗海马凋亡机制研究 第1、36页 1 , * |
| 《中国老年学杂志》 20070630 江湧等 beta-细辛醚对痴呆小鼠学习记忆能力及SOD、GSH2Px和MDA水平的影响 第1126-1127页 第14卷, 第4期 * |
| 《江西中医学院学报》 20020430 黄丽萍等 麝香酮抗痴呆作用的药理学实验研究 第21-23页 1 第14卷, 第4期 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110638823A (en) * | 2019-10-25 | 2020-01-03 | 贵州中医药大学 | Application of icariin in preparation of medicine for treating vascular dementia |
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Legal Events
| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20111130 |