CN102257387A - 严重脓毒病和败血性休克期间用于快速确定死亡高风险病人的方法和试剂盒 - Google Patents

严重脓毒病和败血性休克期间用于快速确定死亡高风险病人的方法和试剂盒 Download PDF

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CN102257387A
CN102257387A CN2009801518443A CN200980151844A CN102257387A CN 102257387 A CN102257387 A CN 102257387A CN 2009801518443 A CN2009801518443 A CN 2009801518443A CN 200980151844 A CN200980151844 A CN 200980151844A CN 102257387 A CN102257387 A CN 102257387A
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complex
level
failure
patients
septic shock
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D·帕扬·德拉加朗代里
A·C·卢卡谢维奇
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Assistance Publique Hopitaux de Paris APHP
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Assistance Publique Hopitaux de Paris APHP
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/26Infectious diseases, e.g. generalised sepsis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
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  • Molecular Biology (AREA)
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  • Biotechnology (AREA)
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  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN2009801518443A 2008-10-28 2009-10-27 严重脓毒病和败血性休克期间用于快速确定死亡高风险病人的方法和试剂盒 Pending CN102257387A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12/259,596 2008-10-28
US12/259,596 US8283131B2 (en) 2008-10-28 2008-10-28 Methods and kits for the rapid determination of patients at high risk of death during severe sepsis and septic shock
US15852009P 2009-03-09 2009-03-09
US61/158,520 2009-03-09
PCT/IB2009/007493 WO2010049818A1 (en) 2008-10-28 2009-10-27 Methods and kits for the rapid determination of patients at high risk of death during severe sepsis and septic shock

Publications (1)

Publication Number Publication Date
CN102257387A true CN102257387A (zh) 2011-11-23

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CN2009801518443A Pending CN102257387A (zh) 2008-10-28 2009-10-27 严重脓毒病和败血性休克期间用于快速确定死亡高风险病人的方法和试剂盒

Country Status (5)

Country Link
US (1) US20110287433A1 (enExample)
EP (1) EP2350646B1 (enExample)
JP (1) JP5619016B2 (enExample)
CN (1) CN102257387A (enExample)
WO (1) WO2010049818A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102636645A (zh) * 2012-04-24 2012-08-15 广州吉赛生物科技有限公司 一种sTERM-1酶联免疫检测试剂盒及其方法
WO2020035063A1 (zh) * 2018-08-17 2020-02-20 北京市心肺血管疾病研究所 血清S100a8/a9复合体水平在急性心肌梗死预后判断中的应用
CN118717994A (zh) * 2024-07-26 2024-10-01 浙江大学医学院附属第一医院(浙江省第一医院) 肝硬化中S100A8/A9诱导NK细胞产生IFNγ的应用
CN119492874A (zh) * 2024-10-30 2025-02-21 首都医科大学附属北京儿童医院保定医院 S100a8/a9在评估感染性疾病病情严重程度中的应用

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KR20180026561A (ko) * 2009-01-19 2018-03-12 비오메리으 환자가 병원감염에 걸릴 가능성을 결정하고 패혈 증후군 진행의 예후를 결정하는 방법
KR20140018249A (ko) * 2011-01-21 2014-02-12 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) 혈중 엔도칸 수준을 측정하는 것에 의해, 패혈증 환자의 호흡부전, 신부전 또는 혈소판감소의 위험을 예측하기 위한 방법 및 키트
FR2970975B1 (fr) 2011-01-27 2016-11-04 Biomerieux Sa Procede et kit pour determiner in vitro le statut immunitaire d'un individu
EP3074536B1 (en) * 2013-11-25 2019-06-19 Children's Hospital Medical Center Temporal pediatric sepsis biomarker risk model
WO2015135071A1 (en) * 2014-03-14 2015-09-17 Hancock Robert E W Diagnostic for sepsis
KR101929772B1 (ko) * 2016-11-02 2018-12-17 연세대학교 산학협력단 패혈증 진단을 위한 정보를 제공하는 방법 및 이를 이용한 키트
WO2021207365A1 (en) * 2020-04-07 2021-10-14 The Wistar Institute Of Anatomy And Biology Reawakening of dormant tumor cells by modified lipids derived from stress activated neutrophils
CN114606308A (zh) * 2022-01-26 2022-06-10 江门市中心医院 脓毒症ards的预后与治疗标志物

Citations (8)

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CN1297922A (zh) * 1999-11-26 2001-06-06 上海博道基因技术有限公司 一种多肽-人钙结合s100蛋白21和编码该多肽的多核苷酸
US20060035221A1 (en) * 2001-12-04 2006-02-16 B.R.A.H.M.S Aktiengesellschaft Use of the glycine n-acyl transferase (gnat) for the diagnosis and therapy of inflammatory diseases and sepsis
US20060234295A1 (en) * 2002-11-20 2006-10-19 Andreas Bergmann Sandwich immunoassay for identifying partial proanp peptides
CN1897959A (zh) * 2003-09-29 2007-01-17 沃伦药品公司 用于治疗和预防脓毒病和粘连形成的组织保护细胞因子
CN101124336A (zh) * 2004-07-23 2008-02-13 阿斯彭生物制药有限公司 用于诊断阑尾炎的方法和设备
CN101193622A (zh) * 2005-06-09 2008-06-04 比奥里波克斯公司 治疗炎性疾病的方法和组合物
EP1950310A1 (en) * 2007-01-23 2008-07-30 Charite-Universitätsmedizin Berlin Method for risk prediction of a postoperative sepsis in a human
WO2008104321A1 (en) * 2007-02-28 2008-09-04 B.R.A.H.M.S. Aktiengesellschaft Method for the selective determination of procalcitonin 1-116 for diagnostic purposes and antibodies and kits for carrying out such a method

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US7659087B2 (en) * 2004-07-23 2010-02-09 Aspenbio Pharma, Inc. Methods and devices for diagnosis of appendicitis
CA2624569A1 (en) * 2005-10-03 2007-04-12 Biosite Incorporated Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes
EP2085486A1 (en) * 2008-02-01 2009-08-05 Assistance Publique - Hopitaux de Paris Methods and kits for the rapid determination of patients at high risk of death during septic shock
US8283131B2 (en) * 2008-10-28 2012-10-09 Assistance Publique-Hopitaux De Paris Methods and kits for the rapid determination of patients at high risk of death during severe sepsis and septic shock

Patent Citations (8)

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CN1297922A (zh) * 1999-11-26 2001-06-06 上海博道基因技术有限公司 一种多肽-人钙结合s100蛋白21和编码该多肽的多核苷酸
US20060035221A1 (en) * 2001-12-04 2006-02-16 B.R.A.H.M.S Aktiengesellschaft Use of the glycine n-acyl transferase (gnat) for the diagnosis and therapy of inflammatory diseases and sepsis
US20060234295A1 (en) * 2002-11-20 2006-10-19 Andreas Bergmann Sandwich immunoassay for identifying partial proanp peptides
CN1897959A (zh) * 2003-09-29 2007-01-17 沃伦药品公司 用于治疗和预防脓毒病和粘连形成的组织保护细胞因子
CN101124336A (zh) * 2004-07-23 2008-02-13 阿斯彭生物制药有限公司 用于诊断阑尾炎的方法和设备
CN101193622A (zh) * 2005-06-09 2008-06-04 比奥里波克斯公司 治疗炎性疾病的方法和组合物
EP1950310A1 (en) * 2007-01-23 2008-07-30 Charite-Universitätsmedizin Berlin Method for risk prediction of a postoperative sepsis in a human
WO2008104321A1 (en) * 2007-02-28 2008-09-04 B.R.A.H.M.S. Aktiengesellschaft Method for the selective determination of procalcitonin 1-116 for diagnostic purposes and antibodies and kits for carrying out such a method

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MASAKI IKEMOTO ET AL.: "New ELISA System for Myeloid-related Protein Complex (MRP8/14) and Its Clinical Significance as a Sensitive Marker for Inflammatory Responses Associated with Transplant Rejection", 《CLINICAL CHEMISTRY》 *
任延波等: "脓毒症早期大鼠肾脏细胞凋亡及炎症细胞因子的变化", 《中国危重病急救医学》 *
张淑伟等: "猪链球菌2型的致病机制", 《生命的化学》 *
王戎机等: "龈沟液12000蛋白质的N-末端氨基酸序列分析及其临床意义", 《中华口腔医学杂志》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102636645A (zh) * 2012-04-24 2012-08-15 广州吉赛生物科技有限公司 一种sTERM-1酶联免疫检测试剂盒及其方法
WO2020035063A1 (zh) * 2018-08-17 2020-02-20 北京市心肺血管疾病研究所 血清S100a8/a9复合体水平在急性心肌梗死预后判断中的应用
CN118717994A (zh) * 2024-07-26 2024-10-01 浙江大学医学院附属第一医院(浙江省第一医院) 肝硬化中S100A8/A9诱导NK细胞产生IFNγ的应用
CN119492874A (zh) * 2024-10-30 2025-02-21 首都医科大学附属北京儿童医院保定医院 S100a8/a9在评估感染性疾病病情严重程度中的应用

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US20110287433A1 (en) 2011-11-24
WO2010049818A1 (en) 2010-05-06
EP2350646A1 (en) 2011-08-03
EP2350646B1 (en) 2016-01-13
JP5619016B2 (ja) 2014-11-05
JP2012507030A (ja) 2012-03-22

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Application publication date: 20111123