CN102245238B - 呼吸致动吸入器 - Google Patents

呼吸致动吸入器 Download PDF

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Publication number
CN102245238B
CN102245238B CN200980149118.8A CN200980149118A CN102245238B CN 102245238 B CN102245238 B CN 102245238B CN 200980149118 A CN200980149118 A CN 200980149118A CN 102245238 B CN102245238 B CN 102245238B
Authority
CN
China
Prior art keywords
opener
inhaler
outlet
compartment
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200980149118.8A
Other languages
English (en)
Chinese (zh)
Other versions
CN102245238A (zh
Inventor
威廉.贝克维尔
约翰.布赖恩特
帕特里克.坎贝尔
查尔斯.库克
克里斯多夫.格罗姆布里奇
尼古拉斯.哈里森
詹姆斯.D.约翰
特里沃.J.彭哈鲁里克
尼古拉斯.斯马特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN102245238A publication Critical patent/CN102245238A/zh
Application granted granted Critical
Publication of CN102245238B publication Critical patent/CN102245238B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043—Non-destructive separation of the package, e.g. peeling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0098—Activated by exhalation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/06—Containers or packages with special means for dispensing contents for dispensing powdered or granular material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0096—Hindering inhalation before activation of the dispenser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
CN200980149118.8A 2008-10-08 2009-10-07 呼吸致动吸入器 Expired - Fee Related CN102245238B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10360208P 2008-10-08 2008-10-08
US61/103,602 2008-10-08
PCT/SE2009/051111 WO2010042034A1 (en) 2008-10-08 2009-10-07 A breath activated inhaler

Publications (2)

Publication Number Publication Date
CN102245238A CN102245238A (zh) 2011-11-16
CN102245238B true CN102245238B (zh) 2014-09-10

Family

ID=42100805

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980149118.8A Expired - Fee Related CN102245238B (zh) 2008-10-08 2009-10-07 呼吸致动吸入器

Country Status (12)

Country Link
US (1) US9155851B2 (enExample)
EP (1) EP2341968B1 (enExample)
JP (1) JP5512686B2 (enExample)
KR (1) KR20110074765A (enExample)
CN (1) CN102245238B (enExample)
AU (1) AU2009302957B2 (enExample)
BR (1) BRPI0920390A2 (enExample)
CA (1) CA2739068A1 (enExample)
MX (1) MX2011003690A (enExample)
NZ (1) NZ591957A (enExample)
RU (1) RU2519384C2 (enExample)
WO (1) WO2010042034A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005057685A1 (de) * 2005-12-01 2007-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Speicher für eine trockene Arzneimittelformulierung sowie diesbezügliche Verfahren und Verwendung
JP5241714B2 (ja) 2006-07-07 2013-07-17 プロテウス デジタル ヘルス， インコーポレイテッド スマートな非経口送達システム
EP2211974A4 (en) 2007-10-25 2013-02-27 Proteus Digital Health Inc INFORMATION SYSTEM FOR LIQUID FLOW CHANNEL
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
WO2010042033A1 (en) * 2008-10-08 2010-04-15 Astrazeneca Ab Inhalation device and method of dispensing medicament
AU2011210648B2 (en) 2010-02-01 2014-10-16 Otsuka Pharmaceutical Co., Ltd. Data gathering system
MY169700A (en) 2010-02-01 2019-05-13 Proteus Digital Health Inc Data gathering system
DE102012104850A1 (de) * 2012-04-05 2013-10-10 Alfred Von Schuckmann Vorrichtung zur portionierten Ausgabe von Medikamenten
FR3050114B1 (fr) * 2016-04-15 2021-12-03 Aptar France Sas Dispositif de distribution de produit fluide synchronise avec l'inhalation.
US20250082872A1 (en) * 2021-01-28 2025-03-13 Iconovo Ab Dry powder inhaler

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1120812A (zh) * 1993-10-26 1996-04-17 泰纳克斯公司 具有吸动活塞的干粉吸入器
WO2002024265A1 (en) * 2000-09-25 2002-03-28 Microdrug Ag Breath-actuation
EP1522325A1 (en) * 2003-10-06 2005-04-13 Bang & Olufsen Medicom A/S Inhaler
US20050081851A1 (en) * 2000-02-01 2005-04-21 Valois S.A.S. Breath actuated dry powder inhaler and tape dose strip

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57500862A (enExample) * 1979-10-30 1982-05-20
GB9024760D0 (en) * 1990-11-14 1991-01-02 Riker Laboratories Inc Inhalation device and medicament carrier
AU1068401A (en) 1999-10-12 2001-04-23 Shl Medical Ab Inhaler
US6871647B2 (en) * 2001-09-19 2005-03-29 Advent Pharmaceuticals Pty Ltd Inhaler
SE0401654D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab A support structure for a medicament
GB0428169D0 (en) 2004-12-23 2005-01-26 3M Innovative Properties Co Pressurized inhalation devices
DE102006043637A1 (de) 2006-05-18 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zerstäuber
DE102006045788A1 (de) * 2006-09-26 2008-03-27 Alfred Von Schuckmann Spender für pulverförmige Massen
CA2673479A1 (en) * 2006-12-22 2008-07-03 Schering Corporation Dispenser dose counter mechanism
CA2681299C (en) * 2007-03-21 2015-02-17 Cipla Limited Multi-dose inhaler device
HUE034380T2 (en) 2007-04-30 2018-02-28 Sun Pharma Advanced Res Co Ltd Inhalation device
AU2009213181B2 (en) * 2008-02-12 2012-02-23 Astrazeneca Ab Inhaler comprising a base having at least one sealed cavity containing medicament

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1120812A (zh) * 1993-10-26 1996-04-17 泰纳克斯公司 具有吸动活塞的干粉吸入器
US20050081851A1 (en) * 2000-02-01 2005-04-21 Valois S.A.S. Breath actuated dry powder inhaler and tape dose strip
WO2002024265A1 (en) * 2000-09-25 2002-03-28 Microdrug Ag Breath-actuation
EP1522325A1 (en) * 2003-10-06 2005-04-13 Bang & Olufsen Medicom A/S Inhaler

Also Published As

Publication number Publication date
CA2739068A1 (en) 2010-04-15
NZ591957A (en) 2013-08-30
EP2341968A4 (en) 2014-04-09
MX2011003690A (es) 2011-04-27
BRPI0920390A2 (pt) 2019-09-24
AU2009302957B2 (en) 2013-03-21
EP2341968A1 (en) 2011-07-13
JP2012505018A (ja) 2012-03-01
RU2519384C2 (ru) 2014-06-10
WO2010042034A1 (en) 2010-04-15
RU2011115404A (ru) 2012-11-20
JP5512686B2 (ja) 2014-06-04
AU2009302957A1 (en) 2010-04-15
US20120048272A1 (en) 2012-03-01
US9155851B2 (en) 2015-10-13
CN102245238A (zh) 2011-11-16
EP2341968B1 (en) 2017-05-10
KR20110074765A (ko) 2011-07-01

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140910

CF01 Termination of patent right due to non-payment of annual fee