CN102198015A - Retractable spiral laminar ring type electrode catheter - Google Patents

Retractable spiral laminar ring type electrode catheter Download PDF

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Publication number
CN102198015A
CN102198015A CN 201110117817 CN201110117817A CN102198015A CN 102198015 A CN102198015 A CN 102198015A CN 201110117817 CN201110117817 CN 201110117817 CN 201110117817 A CN201110117817 A CN 201110117817A CN 102198015 A CN102198015 A CN 102198015A
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ring
retractable
stacked
end
electrode
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CN 201110117817
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Chinese (zh)
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CN102198015B (en
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严钱钱
孙毅勇
廖申扬
杨谦谦
郭俊敏
霍慧君
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上海微创电生理医疗科技有限公司
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Abstract

The invention relates to a retractable spiral laminar ring type electrode catheter used for sympathetic denervation in a renal artery, which comprises a control handle, a catheter body, a control rod, a retractable spiral laminar ring and at least one electrode, wherein the control rod is penetrated through the catheter body with one end of the control rod fixed onto the control handle; the retractable spiral laminar ring comprises at least one laminar ring, one end of the retractable spiral laminar ring is fixed onto the other end of the control rod, the other end of the retractable spiral laminar ring is fixed onto one end of the catheter body, and the end of the catheter body is positioned at the opposite side of the control handle; the at least one electrode is fixed on the retractable spiral laminar ring, each electrode can be used for electric signal extraction and ablation, a lead wire is connected to the lower part of each electrode, and the lead wire extends along the retractable spiral laminar ring inside the retractable spiral laminar ring and extends to the control handle through the catheter body, thereby realizing the electrical connection with the control handle; and the control rod can move relative to the catheter body, thereby adjusting the circumferential dimension of the retractable spiral laminar ring. By using the retractable spiral laminar ring type electrode catheter, the tightness of joint between the electrode and a vascular wall can be adjusted.

Description

可伸缩螺旋叠环式电极导管 Telescopically stacked spiral ring lead

技术领域 FIELD

[0001] 本发明涉及一种电极导管,更具体而言涉及一种用于肾动脉内去交感神经的电极导管。 [0001] The present invention relates to an electrode catheter, and more particularly relates to an electrode catheter for sympathetic renal arteries.

背景技术 Background technique

[0002] 顽固性高血压又称难治性高血压,是指采用生活方式改良和3种或3种以上降压药物(包括一种利尿剂)治疗仍不能有效控制的高血压。 [0002] Also known refractory hypertension refractory hypertension, and improved life refers to the use of 3 or more kinds of antihypertensive drugs (including a diuretic) therapy is still not effectively control hypertension. 实验数据证明高血压与患者肾交感神经兴奋性偏高有关,阻断肾交感神经不但能够使血压下降,并且对交感神经过度激活的慢性器官特异性疾病产生影响;阻断肾交感神经还能改善左心室肥厚和胰岛素抵抗。 Experimental data demonstrate that patients with hypertension and high renal sympathetic activity related to blocking the renal sympathetic nerve not only decrease blood pressure and sympathetic overactivity have an impact on chronic organ-specific diseases; renal sympathetic nerve blockers can improve Left ventricular hypertrophy and insulin resistance.

[0003] 最新的动物及临床实验数据证明采用经皮导管肾脏交感神经射频消融技术可以显著持久地降低顽固性高血压,6个月随访血压平均下降22/12mmHg。 [0003] Recent experimental animal and clinical data demonstrate percutaneous radiofrequency ablation catheter renal sympathetic significantly reduced permanently resistant hypertension, blood pressure at 6 months on average decreased 22 / 12mmHg. 并且采用该方法具有导管介入手段利用射频能量可以对肾动脉部位的交感神经进行阻抗式加热,可减弱其活性甚至伤失传导功能,该方法不仅可以有效治疗顽固性高血压,而且具有微创、并发症少等优点。 With this method and having means for catheterization may be performed using RF energy for heating the impedance site sympathetic renal artery, which can weaken or even damage the active conduction loss, the method not only effectively treat refractory hypertension, and minimally invasive, fewer complications and so on. 业界把这种方法视为突破性进展,并认为它为治疗顽固性高血压开辟了新的大道。 This method is regarded as the industry breakthrough, and that it opens up new avenues for the treatment of resistant hypertension. 射频消融阻断异常电传导在治疗心律失常方面已经比较成熟,但在肾交感神经的阻断应用上还比较少,因为目还缺乏使用简单、安全可靠的专用手术器械,特别是专用的射频消融导管。 Radiofrequency ablation of abnormal electrical conduction in the treatment of cardiac arrhythmias is relatively mature, but in the renal sympathetic nerve blockade application is still relatively small, because the project still lacks easy to use, safe and reliable specialized surgical instruments, especially dedicated radiofrequency ablation catheter.

[0004] 相关文献中或专利中有报道用于肾动脉交感神经射频加热式器械,但与达到最终使用要求还有明显的距离。 [0004] Patent literature or artery has been reported for renal sympathetic RF heating devices, but also to achieve end-use requirements appreciable distance. CN201469401U中提到一种螺旋型环肾动脉交感神经射频消融电极导管,它可沿肾动脉形成非环状封闭的连续接触消融。 A spiral type mentioned CN201469401U ring sympathetic nerve renal artery radiofrequency ablation catheter electrode that can form a non-cyclic artery closed continuous contact along the renal ablation. 但电极与血管壁贴合的电极贴壁紧密程度无法调节,并且不能实施监控消融温度设计,难以保证消融程度,有消融程度过浅时达不到疗效、或消融程度造成穿孔等风险。 But the electrode and the vessel wall fit tightly adherent extent can not be adjusted, and can not be implemented to monitor the ablation temperature design, it is difficult to ensure that the degree of ablation, ablation have not reach the extent of the effect is too shallow, causing perforation or ablation degree of risk.

发明内容 SUMMARY

[0005] 本发明的目的是提供一种容易实现对电极与血管壁贴合的电极贴壁紧密程度的调节的用于肾动脉内去交感神经的电极导管。 [0005] The object of the present invention is to provide an easy to implement for the lead within the renal artery sympathetic regulation of the vessel wall electrode bonded tightly adherent extent.

[0006] 根据本发明,提供一种可伸缩螺旋叠环式电极导管,所述可伸缩螺旋叠环式电极导管用于肾动脉内去交感神经,所述可伸缩螺旋叠环式电极导管包括:控制手把;导管管身;控制杆,所述控制杆穿过所述导管管身,所述控制杆的一端固定到所述控制手把;可伸缩螺旋叠环,所述可伸缩螺旋叠环包括至少一个叠环,所述可伸缩螺旋叠环的一端固定到所述控制杆的另一端,所述可伸缩螺旋叠环的另一端固定到所述导管管身的一端,所述导管管身的所述一端位于所述控制手把的相反侧;和固定在所述可伸缩螺旋叠环上的至少一个电极,所述至少一个电极均能够用于提取电信号和消融,每个电极下均连接有导线,所述导线在所述可伸缩螺旋叠环内沿着所述可伸缩螺旋叠环延伸,并经过所述导管管身延伸到所述控制手把,从而与所述控制手把电连接;其 [0006] According to the present invention, there is provided a telescoping lead helical stacked ring, said ring telescopically stacked coil lead for sympathetic denervation within the renal artery, the retractable helical electrode stacked ring conduit comprising: a control handle; catheter tube body; lever, said lever body through the catheter tube, the end of the control lever fixed to the control handle; telescopically stacked spiral ring, said ring telescopically stacked coil ring comprising at least one stack, the retractable end of the spiral on ring secured to the other end of the lever, the retractable ring further helical bundle end to one end of the body of the catheter tube, said catheter tube body the opposite end of said control handle side; and a retractable fixed to the at least one electrode ring on the helical stack, the at least one electrode for extracting electric signals and are capable of ablation, lower each electrode connected to the wires that may be retractable within the spiral stacked telescopically along the ring-on-ring coil extending through the catheter tube and extends into the control handle body, whereby the electrical control handle connection; the 中所述控制杆能够相对于所述导管管身移动,从而调整所述可伸缩螺旋叠环的周向尺寸。 Said control lever relative to the catheter tube body moves, thereby adjusting the retractable helical circumferential dimension of the ring stack.

[0007] 根据本发明的可伸缩螺旋叠环式电极导管,当所述控制杆相对于所述导管管身移动时,能够调整所述可伸缩螺旋叠环的周向尺寸,从而实现对电极与血管壁贴合的电极贴壁紧密程度的调节。 [0007] The scalable spiral stacked ring electrode catheter of the present invention, when the control rod relative to the catheter tube body movement, able to adjust the retractable helical circumferential dimension stacked ring, and the counter electrode in order to achieve vessel wall electrode bonded tightly adherent degree of adjustment. 所述至少一个电极均能够用于提取电信号和消融,可以避免多次调整器械并进行一次消融,安全且效率高。 At least one electrode for extracting electric signals and are capable of ablation devices can be avoided and a several adjustments ablation, safe and efficient.

[0008] 优选地,所述控制杆的长度设计为使得:在所述控制杆朝向肾移动后能拉伸所述可伸缩螺旋叠环,使所述可伸缩螺旋叠环通过中央大血管,并进入到肾动脉内。 Length [0008] Preferably, the control lever is designed so that: after the movement toward the kidney which can stretch the stacked telescopically helical loop the control lever, the retractable ring through the central spiral stacked great vessels, and into the renal artery.

[0009] 优选地,所述控制杆的所述另一端包括一段软管、圆形软球或锥形软头,以避免对血管的损伤。 The other end of the [0009] Preferably, the control lever comprises a length of hose, circular or tapered soft soft ball head, in order to avoid damage to the vessel.

[0010] 优选地,所述控制杆的所述一端固定到所述控制手把上的调节旋钮上,从而通过所述调节旋钮移动所述控制杆以调整所述可伸缩螺旋叠环的周向尺寸,进而调整其上电极与血管壁贴合的电极贴壁紧密程度。 The end [0010] Preferably, the control rod is secured to the control knob on the handle, so that by the movement of the adjustment knob to adjust the control rod telescopically stacked helical circumferential ring size, thereby adjusting the electrode on which the vessel wall is bonded tightly adherent extent.

[0011 ] 优选地,所述控制杆包括氟类涂层,从而有效提高控制杆移动过程中的滑爽性。 [0011] Preferably, the control rod comprises a fluorine-based coating, thereby effectively improving slip control rod during movement.

[0012] 优选地,每一个电极下均埋植有温度传感器,用于监控消融过程中的温度,从而实现消融过程中的温度精确监控。 [0012] Preferably, the electrodes are implanted in each have a temperature sensor for monitoring the temperature of the ablation process, the ablation process to achieve accurate temperature monitoring.

[0013] 优选地,所述至少一个电极沿着所述可伸缩螺旋叠环的周向和轴向排布。 [0013] Preferably, the at least one electrode is arranged along the circumferential and axial telescopic helical stack ring. 因此,电极在血管周向和轴向均有排布,可以方便地同时提取各个部位电信号并确认消融位置,而不用移动调整电极的位置,方便安全省时。 Thus, the electrodes are arranged in the axial direction and can be easily extracted simultaneously in all parts of the electrical signal and perivascular confirmed the ablation position, without moving the adjustment position of the electrode to facilitate the safe saving.

[0014] 优选地,所述可伸缩螺旋叠环的两端均设有延伸到叠环的圆中心并向叠环的两侧延伸的支撑杆,所述可伸缩螺旋叠环的所述一端的所述支撑杆连接到所述控制杆的所述另一端,所述可伸缩螺旋叠环的所述另一端的所述支撑杆连接到所述导管管身的所述一端。 [0014] Preferably, both ends of the retractable ring equipped with a helical stack support rod extending on both sides of the center of the circle and extending into the stack of stacked rings of the ring, said end of said retractable ring helix bundle the support rod is connected to the other end of the control lever, the retractable support rods of the other end of said helical stack ring is connected to one end of the catheter tube itself. 进一步优选地,在所述支撑杆与所述控制杆的所述另一端的连接处以及所述支撑杆与所述导管管身的所述一端的连接处形成圆滑结构,以避免刺伤血管。 Further preferably, the rounded structure is formed at the connection of the support bar and the other end of the control rod and is connected at the one end of the support bar and the body of the catheter tube to prevent the blood vessel puncture.

[0015] 优选地,所述控制杆是中空管状。 [0015] Preferably, the control rod is a hollow tube. 中空管状结构可以兼作导丝腔或通造影剂等用途。 Hollow tubular structure may serve as the guidewire lumen or through the use of contrast agent. 进一步优选地,将所述控制杆的中空腔套在导丝上,并沿着所述导丝推进到目标血管。 Further preferably, the control lever is set in the cavity over the guidewire and advanced along the guidewire to the target vessel.

[0016] 优选地,所述可伸缩螺旋叠环的轴向投影成圆环状。 [0016] Preferably, the retractable ring axially overlapping spiral projection annularly. 进一步优选地,所述至少一个叠环包括多个叠环,随着所述多个叠环离开所述导管管身由近到远,所述多个叠环的环径依次减小,以更适应远端血管直径减小的特点。 Further preferably, the at least one stack comprises a plurality of ring-on-ring, a plurality of stacked rings as to leave the catheter body tube from near to far, the plurality of stacked rings of the ring diameter gradually decreases, more adaptation reduced diameter distal vessel characteristics. 所述圆环的环径为3-20mm,更适合的环径为3_15mm0 The annular ring diameter of 3-20mm, more suitable ring diameter 3_15mm0

[0017] 优选地,将所述至少一个电极提取电信号较强的部位作为消融靶点,通过对比消融前后信号强度减弱程度来判断消融效果,从而提高消融准确性和有效性。 [0017] Preferably, the at least one electrode of said electric signal extracted as strong ablation target site, the ablation is determined by comparing the effect of the degree of decreased signal intensity before and after ablation, thereby improving the accuracy and effectiveness of the ablation. 进一步优选的是:选取多个目标消融靶点对应电极或电极对同时进行消融,以有效节约手术时间;或者选择临近交错排布的电极进行消融,可获得不连续的消融灶,以避免血管狭窄。 It is further preferred that: a plurality of selected target corresponding to the target ablation electrodes or electrode pairs for ablation, in order to effectively save the operation time; or select an electrode arranged near staggered ablation, discontinuous lesions obtained, in order to avoid stenosis .

[0018] 所述可伸缩螺旋叠环的叠环数优选为1-5个,更优选为2个。 [0018] The retractable helical stacked rings on ring number is preferably 1-5, more preferably 2.

[0019] 优选地,通过电阻焊接、热焊接或胶水粘结将所述支撑杆连接到所述控制杆的所述另一端和所述导管管身的所述一端。 [0019] Preferably, the resistance welding, thermal welding or glue bonded to said support bar and said other end of said catheter tube having one end connected to the body control lever.

[0020] 优选地,所述可伸缩螺旋叠环由中心骨架和外层套管构成。 [0020] Preferably, the retractable helix bundle composed of a central skeleton ring and the outer sleeve. 所述导线可以通过所述电极下方的开孔进入所述中心骨架上的所述外层套管内。 The wires may be said outer sleeve into the central skeleton through the openings below the electrode. 所述中心骨架可以使用各类形状记忆合金材料,如镍钛合金、不锈钢、钛合金等。 The central skeleton may be used various kinds of shape memory alloy material, such as nitinol, stainless steel, titanium and the like. 所述外层套管可以是聚酯类、聚氨酯、聚酰胺等具有良好生物相容性的高分子材料,外层套管选用具有弹性的高分子材料时更适合于产品的组装加工。 The outer sleeve may be polyesters, polyurethanes, polyamides and other polymer materials with good biocompatibility, when the outer sleeve of polymeric material having an elasticity selected assembly process more suitable for the product. [0021] 优选地,所述控制杆可以采用镍钛合金、不锈钢等金属材料、或聚酰亚胺、尼龙等硬质高分子材料制成。 [0021] Preferably, the control lever may employ nickel-titanium alloy, a metal material such as stainless steel, or polyimide, nylon and other rigid polymeric material.

[0022] 优选地,所述控制杆的直径为0. 3-1. 5mm。 Diameter [0022] Preferably, the control lever is 0. 3-1. 5mm.

[0023] 优选地,所述可伸缩螺旋叠环上排布的所述电极的数量为1-30个,更适宜的数量为3-15个。 [0023] Preferably, the retractable helical stack number of the electrodes arranged on the ring is from 1 to 30, more suitably in an amount of from 3 to 15.

[0024] 优选地,所述导管管身的内径比所述控制杆的外径大0. 1-0. 5mm,以便控制杆能在 [0024] Preferably, the inner diameter of the catheter body of the tube of the control rod than the outer diameter of 0. 1-0. 5mm, so that the control rod can

其中来回移动。 Which move back and forth.

附图说明 BRIEF DESCRIPTION

[0025] 图1是根据本发明的可伸缩螺旋叠环式电极导管的示意图。 [0025] FIG. 1 is a schematic view of the lead screw ring telescopic stack according to the present invention.

[0026] 图2是采用中空控制杆结构的该可伸缩螺旋叠环式电极导管的示意图。 [0026] FIG. 2 is a schematic diagram of the telescopic lead helical stacked hollow ring structure using a lever.

[0027] 附图标记的说明 [0027] DESCRIPTION OF REFERENCE NUMERALS

[0028] 1导管管身 [0028] 1 catheter tube body

[0029] 2控制杆 [0029] The second control lever

[0030] 3可伸缩螺旋叠环 [0030] 3 telescopically stacked spiral ring

[0031] 4 电极 [0031] 4 electrode

[0032] 5支撑杆 [0032] support rod 5

[0033] 6 肾 [0033] 6 Kidney

[0034] 7 导丝 [0034] 7 guidewire

[0035] RP交感神经 [0035] RP sympathetic

具体实施方式 Detailed ways

[0036] 以下将结合附图详细说明本发明的实施例。 [0036] Embodiments of the invention will be described in detail in conjunction with the accompanying drawings. 为便于说明,以下将靠近控制手把即操作者或远离肾的一端称为“近端”,将远离控制手把即操作者或靠近肾的一端称为“远端”。 For convenience of explanation, the following will be close to the handle that the operator or control end remote from the kidney called the "proximal", i.e., the remote operator control handle or near the end of the kidney called the "distal."

[0037] 参见图1,用于肾动脉内去交感神经RP的可伸缩螺旋叠环式电极导管包括:控制手把(图中未示出);导管管身1 ;控制杆2,所述控制杆2穿过所述导管管身1,所述控制杆2的一端(近端)固定到所述控制手把;可伸缩螺旋叠环3,所述可伸缩螺旋叠环3的一端(远端)固定到所述控制杆2的另一端(远端),所述可伸缩螺旋叠环3的另一端(近端) 固定到所述导管管身1的一端(远端),所述导管管身1的所述一端位于所述控制手把的相反侧;和固定在所述可伸缩螺旋叠环3上的至少一个电极4,所述至少一个电极4沿着所述可伸缩螺旋叠环3的周向和轴向排布,所述至少一个电极4均能够用于提取电信号和消融; 其中所述控制杆2能够相对于所述导管管身1移动,从而调整所述可伸缩螺旋叠环3的周向尺寸。 [0037] Referring to Figure 1, the retractable ring spiral stacked lead to renal artery sympathetic denervation RP includes: a control handle (not shown); catheter tube body 1; lever 2, the control rod body 2 through the catheter tube 1, the end of the control lever 2 (the proximal end) fixed to the control handle; telescopically stacked spiral ring 3, the retractable end of the coil ring 3 stack (distal end ) fixed to the other end of the control 2 (distal end) of the rod, the other end of the coil stack retractable ring 3 (proximal end) fixed to the catheter tube body 1 at one end (distal end), the catheter tube the body 1 is located at one end of the control handle of the opposite side; and at least one electrode is fixed to the retractable helical stack 3 on the ring 4, said at least one electrode 4 may be stacked telescopically along the spiral ring 3 the circumferential and axial arrangement of the at least one electrode 4 can be used to extract both electrical and ablation; wherein the control rod 2 with respect to the catheter tube body 1 is moved to adjust the retractable helical bundle circumferential dimension of the ring 3.

[0038] 具体讲,所述可伸缩螺旋叠环3的叠环数为1-5个,更适合的叠环数为2个;每个螺旋连接构成一体形叠环。 [0038] Specifically, the retractable helical stacked ring on ring 3 is 1-5, more suitable for the two stacks of rings; each connected to form a helical shape on ring. 叠环的轴向投影优选但不限于成圆环状,环径为3-20mm,更适合的环径为3-15mm。 Axial projection of the stack ring is preferably, but not limited to an annular shape, the ring diameter of 3-20mm, more suitable ring diameter of 3-15mm. 在实践中可为本产品制定在该范围内一个特定数据的系列规格。 In practice, this product can develop a specific data within the scope series specifications. 可以采用每个环直径相同的设计,也可以采用环径由近到远(离开所述导管管身1由近到远)依次减小的设计,以更适应远端血管直径减小的特点。 Design may be the same diameter each ring, the ring may be used from near to far path (away from the body of the catheter tube 1 from near to far) gradually decreases designed to accommodate more features a reduced diameter distal vessel. 手术中,应选择与目标消融血管直径相 Surgery should be selected with respect to the target vessel diameter ablated

5当或略大的规格。 5 When or slightly larger size.

[0039] 可伸缩螺旋叠环3的近端和远端均设有延伸到叠环的圆中心并向叠环的两侧延伸的支撑杆5,分别连接到导管管身1的所述一端(远端)和控制杆2的所述另一端(远端)上。 [0039] telescopically stacked coil proximal and distal rings 3 are provided on both sides of the support rods 5 extending central circle extend into the stack of rings to overlap the rings are connected to one end of the body 1 of the catheter tube ( the distal end) and the control rod 2 on the other end (distal end). 连接方式可以是电阻焊接、热焊接、胶水粘结等方式,并形成圆滑结构,以避免刺伤血管。 Attachment means may be resistance welding, hot welding, glue, bonding or the like, and is formed smooth structure, to avoid vascular puncture. 可伸缩螺旋叠环3由中心骨架和外层高分子套管构成。 Retractable helix bundle composed of a central skeleton ring 3 and the outer sleeve polymer. 中心骨架可以使用各类形状记忆合金材料,如镍钛合金、不锈钢、钛合金等。 Central skeleton may be used various kinds of shape memory alloy material, such as nitinol, stainless steel, titanium and the like. 使用模具,通过热处理、拉伸等方式可以将原材料加工成所需尺寸的螺旋形状。 Using a mold, the raw material may be processed into a spiral shape desired size by the heat treatment, stretching or the like. 外层套管可以是聚酯类、聚氨酯、聚酰胺等具有良好生物相容性的高分子材料,外层套管选用具有弹性的高分子材料时更适合于产品的组装加工。 The outer sleeve may be polyesters, polyurethanes, polyamides and other polymer materials with good biocompatibility, when the outer sleeve of polymeric material having an elasticity selected assembly process more suitable for the product.

[0040] 控制杆2可以相对于导管管身1来回移动。 [0040] the control lever relative to the catheter tube 2 can be moved back and forth a body. 向前(即朝向肾6)移动控制杆2时, 可以将可伸缩螺旋叠环3的叠环间距拉疏,同时叠环直径减小,实现叠环伸缩目的。 Forward (i.e., toward the kidney. 6) the control rod 2, the coil may be stacked telescopically pulled sparse spacing ring on ring 3 while overlapping ring diameter is reduced, to achieve the purpose of telescopically stacked rings. 控制杆2可以采用镍钛合金、不锈钢等金属材料、或聚酰亚胺、尼龙等硬质高分子材料制成。 The control lever 2 may be employed nickel-titanium alloy, a metal material such as stainless steel, or polyimide, nylon and other rigid polymeric material. 在控制杆2外作氟类涂层可以有效提高控制杆2移动过程中的滑爽性。 In the control rod 2 as a fluorine-based outer coating layer can improve the slip 2 in the control rod movement. 控制杆2既可以是棒状,也可以是管状;中空的管状结构可以兼作导丝腔或通造影剂等用途。 The control lever 2 may be a rod-shaped, may be tubular; hollow tubular structure may serve as the guidewire lumen or through the use of contrast agent. 控制杆2直径为0. 3-1. 5mm,长度需要足够长,以保证向前移动后能拉直伸缩环,使螺旋叠形圈通过中央大血管,并进入到肾动脉内。 The control rod 2 having a diameter of 0. 3-1. 5mm, length need be long enough to ensure that the forward movement of the ring can be straightened stretch, the spiral ring stack through the central trunk, and into the renal artery. 为了避免对血管的损伤,控制杆2的所述另一端(远端)可以增加一段软管、或圆形软球、或锥形软头等。 In order to avoid damage to the vessel, the other end of the control lever 2 (the distal end) can increase the length of hose, soft ball or rounded, tapered or soft top.

[0041] 可伸缩螺旋叠环上排布的电极数量为电极数量为1-30个,更适宜的数量为3-15 个。 [0041] The number of electrodes stacked telescopically helical ring is arranged on the electrode number 1 to 30, more suitably in an amount of from 3 to 15. 每个电极下均连接有导线,可以通过锡焊、电阻焊、机械压接等方式实现。 Under each electrode lead wire is connected, by soldering, resistance welding, mechanical crimping, etc. to achieve. 导线通过电极下方的开孔进入可伸缩螺旋叠环的中心骨架上的外层套管内,并延伸到导管管身,最后到控制手把末端的电气连接插座上。 Wire into the helical inner telescopic sleeve outer ring of the central skeleton stack through the opening below the electrode, and extends to the catheter tube body, and finally to the end of the control handle is connected to the electrical outlet.

[0042] 导管管身1为中空结构,导管管身1的内径比控制杆2的外径大0. 1-0. 5mm,以便控制杆2能在其中来回移动。 [0042] The catheter body 1 is a hollow tube structure, the inner diameter of the catheter tube 2 the outer diameter of the rod body 1 is larger than the control 0. 1-0. 5mm, so that the control rod 2 can move back and forth therein. 导管近端装有控制手把;通过导管管身1的控制杆2也固定到控制手把上的调节旋钮(图中未示出)上。 The proximal end of the catheter with a control handle; through the catheter tube 1, the lever body 2 is also fixed to the adjustment knob (not shown) on the control handle. 通过调节旋钮,可以移动控制杆2调节叠环的周向尺寸(直径),从而调整其上电极4与血管壁贴合的电极贴壁紧密程度。 By adjusting knob adjusting lever 2 can be moved in the circumferential direction on ring size (diameter), thereby adjusting the upper electrode 4 and the electrode bonded to the vessel wall how closely adherent. 导管管身1 可以选用各类具有良好生物相容性高分子材料制成。 Catheter tube body 1 may be selected various types of polymer materials with good biocompatibility.

[0043] 手术中可以使用常用的介入长鞘放置导管。 [0043] Surgical intervention can be used in conventional long sheath catheter placement. 参见图2,使用介入导丝7并先将其放置到位后,将本控制杆2的中空腔套在导丝7上,并沿着导丝7向前推进到目标血管。 Referring to Figure 2, using 7 and interventional guidewire in place after it first, the control lever in this cavity 2 over the guide wire 7, and advances forward along the guide wire 7 to the target vessel.

[0044] 当将叠环送入预定血管内并调整控制杆2使电极4贴壁良好时,所有电极4均可用于提取神经电信号和消融目的。 [0044] When the laminated ring into the vessel and a predetermined control lever 2 good adherence of the electrode 4, all of the electrodes 4 can be used for extracting neural signal and ablation purposes. 将所提取信号较强的部位即神经区域作为消融靶点,通过对比消融前后信号强度减弱程度,可判断消融效果,从而提高消融准确性和有效性;各电极下均埋植有温度传感器(图中未示出),可以实现消融过程中的温度精确监控。 The stronger the signal extracting portion ablation target area as a neural i.e., by comparing the degree of decreased signal intensity before and after ablation, the ablation effect can be determined, thereby improving the accuracy and effectiveness of the ablation; at each temperature sensor electrodes are implanted (FIG. not shown), may be implemented accurately monitor the temperature of the ablation process.

[0045] 手术中,既可以配合弥散电极进行单极消融,也可以选取临近电极进行双极消融; 根据标测结果,可选取多个目标消融靶点对应电极或电极对同时进行消融,可以有效节约手术时间。 [0045] In operation, the dispersion may be with the monopolar ablation electrode, can also select an ablation adjacent bipolar electrodes; The results of the mapping, ablation target can select the target corresponding to a plurality of electrodes or electrode pairs for ablation can be effectively saving operation time. 选择临近交错排布的电极进行消融可获得不连续的消融灶,以避免血管狭窄。 Interleaving selection electrode arranged near ablate lesions discontinuous obtained, to avoid vascular stenosis.

[0046] 本发明不局限于具体实施方式中所描述的具体内容。 [0046] SUMMARY The present invention is not limited to specific embodiments described herein. 本发明所提供的可伸缩螺旋叠环式电极导管除了肾动脉内消融去交感神经治疗高血压用途外,也适合于其他血管内的消融手术。 The present invention provides a retractable helical electrode catheters stacked ring in addition to sympathetic ablation of renal artery hypertension therapeutic purposes, but also for ablation procedures in other vessels.

Claims (10)

1. 一种可伸缩螺旋叠环式电极导管,所述可伸缩螺旋叠环式电极导管用于肾动脉内去交感神经,所述可伸缩螺旋叠环式电极导管包括:控制手把;导管管身;控制杆,所述控制杆穿过所述导管管身,所述控制杆的一端固定到所述控制手把;可伸缩螺旋叠环,所述可伸缩螺旋叠环包括至少一个叠环,所述可伸缩螺旋叠环的一端固定到所述控制杆的另一端,所述可伸缩螺旋叠环的另一端固定到所述导管管身的一端,所述导管管身的所述一端位于所述控制手把的相反侧;和固定在所述可伸缩螺旋叠环上的至少一个电极,每个电极均能够用于提取电信号和消融,每个电极下均连接有导线,所述导线在所述可伸缩螺旋叠环内沿着所述可伸缩螺旋叠环延伸,并经过所述导管管身延伸到所述控制手把,从而与所述控制手把电连接;其中所述控制杆能够相对于所述 1. A scalable spiral stacked lead ring, said ring telescopically stacked coil lead for sympathetic denervation within the renal artery, the retractable ring lead helical stack comprising: a control handle; catheter tube body; lever, said lever body through the catheter tube, the end of the control lever fixed to the control handle; telescopically stacked spiral ring, the retractable ring comprises at least one helical stack stacked ring, One end of the retractable stacked ring fixed to the other end of the coil of the control lever, the other end of the coil stack retractable ring is secured to one end of the body of the catheter tube, said catheter tube is located at one end of the body the opposite side of said control handle; retractable and fixed to the at least one electrode ring on the helical stack, can be used to extract each electrode and electrical ablation, the lead wire is connected to each electrode, said wire the spiral ring extends telescopically stacked within the ring along the helical stacked telescopically, through the catheter tube and extends into the control handle body, to be connected electrically to the control handle; wherein said control lever with respect to the 管管身移动,从而调整所述可伸缩螺旋叠环的周向尺寸。 Tube body movement, thereby adjusting the retractable helical circumferential dimension stacked rings.
2.根据权利要求1所述的可伸缩螺旋叠环式电极导管,其特征在于所述控制杆的长度设计为使得:在所述控制杆朝向肾移动后能拉伸所述可伸缩螺旋叠环,使所述可伸缩螺旋叠环通过中央大血管,并进入到肾动脉内。 The retractable spiral stacked ring electrode catheter according to claim 1, characterized in that the length of the lever is designed such that: after the movement toward the kidney which can stretch the telescopic control rod in the helical stack ring , the retractable ring coil stack through the central trunk, and into the renal artery.
3.根据权利要求1所述的可伸缩螺旋叠环式电极导管,其特征在于:所述控制杆的所述一端固定到所述控制手把上的调节旋钮上,从而通过所述调节旋钮移动所述控制杆以调整所述可伸缩螺旋叠环的周向尺寸。 The retractable spiral stacked ring electrode catheter according to claim 1, wherein: said one end of the control rod is fixed to the control knob on the handle, so that by moving the adjustment knob said control lever to adjust the ring telescopically stacked helical circumferential dimension.
4.根据权利要求1所述的可伸缩螺旋叠环式电极导管,其特征在于:所述至少一个电极沿着所述可伸缩螺旋叠环的周向和轴向排布,所述电极的数量为1-30个。 The retractable spiral stacked ring electrode catheter according to claim 1, wherein: said at least one electrode may be arranged along the circumferential and axial stretching on ring helix, the number of the electrodes 1-30.
5.根据权利要求1至4中任一项所述的可伸缩螺旋叠环式电极导管,其特征在于:所述可伸缩螺旋叠环的两端均设有延伸到叠环的圆中心并向叠环的两侧延伸的支撑杆,所述可伸缩螺旋叠环的所述一端的所述支撑杆连接到所述控制杆的所述另一端,所述可伸缩螺旋叠环的所述另一端的所述支撑杆连接到所述导管管身的所述一端。 The retractable spiral stacked ring electrode catheter according to any one of claims 1 to 4, wherein: said retractable helix bundle ends are provided with a circular ring extends into the center of the ring to the stack the other end of the support rod extending on both sides of the stack ring, the retractable end of the coil of the stack ring is connected to the support rods of the control rod, the other end of said spiral telescopic stack ring the support rod is connected to one end of the catheter tube itself.
6.根据权利要求1至4中任一项所述的可伸缩螺旋叠环式电极导管,其特征在于:所述可伸缩螺旋叠环的轴向投影成圆环状。 1 according to any of claim 4-1 ring telescopically stacked lead helical claim, wherein: said retractable ring axially overlapping spiral projection annularly.
7.根据权利要求6所述的可伸缩螺旋叠环式电极导管,其特征在于:所述圆环的环径为3-20mmo The telescopic according to claim 6 ring lead helical stack, wherein: the diameter of the annular ring is 3-20mmo
8.根据权利要求6所述的可伸缩螺旋叠环式电极导管,其特征在于:所述至少一个叠环包括多个叠环,随着所述多个叠环离开所述导管管身由近到远,所述多个叠环的环径依次减小。 Scalable spiral stacked ring electrode catheter according to claim 6, wherein: said at least one stack comprises a plurality of ring-on-ring, as the ring away from said plurality of stacked body by a catheter tube near to far, the plurality of stacked rings ring diameter gradually decreases.
9.根据权利要求1至4中任一项所述的可伸缩螺旋叠环式电极导管,其特征在于:所述可伸缩螺旋叠环由中心骨架和外层套管构成。 According to any one of claim 4-1 ring telescopically stacked lead helical claim, wherein: said retractable helix bundle composed of a central skeleton ring and the outer sleeve.
10.根据权利要求9所述的可伸缩螺旋叠环式电极导管,其特征在于:所述中心骨架由形状记忆合金材料制成。 10. The scalable according to claim 9 stacked spiral ring lead, wherein: said central skeleton is made of a shape memory alloy material.
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