CN102197808B - Cycloxaprid water dispersible granule and preparation method thereof - Google Patents
Cycloxaprid water dispersible granule and preparation method thereof Download PDFInfo
- Publication number
- CN102197808B CN102197808B CN 201110081047 CN201110081047A CN102197808B CN 102197808 B CN102197808 B CN 102197808B CN 201110081047 CN201110081047 CN 201110081047 CN 201110081047 A CN201110081047 A CN 201110081047A CN 102197808 B CN102197808 B CN 102197808B
- Authority
- CN
- China
- Prior art keywords
- cycloxaprid
- water dispersible
- dispersible granule
- mixing
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the field of insecticide, and discloses a cycloxaprid water dispersible granule, and a preparation method thereof. The water dispersible granule comprises an effective component of cycloxaprid. The preparation method comprises: adding a moistening agent, a dispersing agent, an adsorbent, a disintegrating agent, a binder, a stabilizing agent and a carrier to the cycloxaprid; uniformly mixing the mixture; carrying out air jet pulverization to prepare a wettable powder; carrying out kneading, pelletizing, drying and screening to obtain products. The cycloxaprid water dispersible granule provided by the present invention is one of agricultural formulations of the cycloxaprid, and has advantages of quick disintegrating, good dispersibility, high suspending rate, good stability, easy storing, convenient using and no requirement of solvent. In addition, with the present invention, active ingredients are protected such that the active ingredients can play a role.
Description
Technical field
The present invention relates to a kind of cycloxaprid formulation and preparation method thereof, particularly cycloxaprid water dispersible granule and preparation method thereof.
Background technology
Cycloxaprid is a kind of high activity, the hypotoxic agricultural insecticide of East China University of Science's research invention.Cycloxaprid is efficient to homoptera pest, lepidoptera pest also had the anti-effect of holding concurrently, particularly paddy rice Severe pests brown planthopper and Alien Invasive Species Bemisia tabaci are had good control efficiency, can be used in addition the control of the insects such as cabbage aphid, diamond-back moth, rice leaf roller.Synthetic and the purposes of cycloxaprid has been applied for Chinese invention patent and International PCT patent at present, and relevant cycloxaprid formulation yet there are no relevant report.
Summary of the invention
So one of technical problem to be solved by this invention is providing a kind of cycloxaprid water dispersible granule for the deficiencies in the prior art; this cycloxaprid water dispersible granule is a kind of of the agricultural formulation of cycloxaprid; has fast, the good dispersion of disintegration; suspensibility height, good stability, be beneficial to storage, easy to use, do not need solvent, the protection active ingredient characteristics such as play a role.
Two of technical problem to be solved by this invention is to provide the preparation method of above-mentioned cycloxaprid water dispersible granule.
Cycloxaprid water dispersible granule as first aspect present invention is characterized in that, comprises the active ingredient cycloxaprid, and formulation is water dispersible granules.
Described cycloxaprid water dispersible granule also comprises auxiliary agent and carrier.
Described auxiliary agent is one or both and the two or more mixing in wetting agent, dispersant, adsorbent, disintegrant, binding agent, the stabilizing agent.
In a preferred embodiment of the invention, take the raw material total amount of cycloxaprid water dispersible granule as 100%, the weight proportion of each raw material is: cycloxaprid 2～90%, wetting agent 1～10%, dispersant 2～15%, adsorbent 1～5%, disintegrant 0～10%, binding agent 1～10%, stabilizing agent 1～10%, all the other are carrier.
In above-mentioned specific embodiment, described wetting agent is a kind of or both combinations in anionic surfactant, the nonionic surface active agent.
Described anionic surfactant is one or both and the two or more mixing of pulling open in powder, lauryl sodium sulfate, NNO, lignosulfonates, the calcium dodecyl benzene sulfonate.
Described nonionic surface active agent is one or both and the two or more combination in alkyl polyoxyethylene ether OP series, 602 series, 1601 series, the By series.
Described dispersant is one or both and the two or more mixing in anionic surfactant, nonionic surface active agent, water-soluble high-molecular substance, inorganic dispersant, sulfite paper slurries and the solid natural products thereof.
Described anionic surfactant is one or both and the two or more mixing in Sulfonates, polycarboxylic acid salt, the phosphoric acid salt.
Described nonionic surface active agent is polyoxyethylene polyoxyethyl propyl ether block copolymers or alkylphenol-polyethenoxy base phosphate.
Described water-soluble high-molecular substance is one or both and the two or more mixing in polyvinyl alcohol, polyethylene glycol, the polyvinylpyrrolidone.
Described inorganic dispersant is condensed phosphate.
Described Sulfonates is one or both and the two or more mixing in the alkylaryl sulfonates of naphthalene sulfonate, alkyl formaldehyde condensation products sulfonate, fatty alcohol ethylene oxide adduct sulfonate, alkylphenol-polyethenoxy base sulfonate, lignin and derivative sulfonate thereof, polymerization.
Described polycarboxylic acid salt is Sodium Polyacrylate.
Described phosphoric acid salt is one or both the combination in fatty alcohol ethylene oxide adduct phosphate, the alkylphenol-polyethenoxy base ether phosphate salt.
Described adsorbent is one or both and the two or more mixing in diatomite, attapulgite, calcium carbonate, white carbon, thenardite, the avicel cellulose etc.
Described disintegrant is one or both and the two or more mixing in urea, ammonium sulfate, calcium chloride, sodium chloride, magnesium chloride and the aluminium chloride.
Described binding agent is one or both and the two or more mixing in soluble starch, dextrin, gum Arabic and the polyvinyl acetate.
Described stabilizing agent is sodium hydroxide, sodium carbonate, sodium bicarbonate, one or both in benzoic acid, the citric acid and two or more mixing.
Described carrier is one or both and the two or more mixing in diatomite, white carbon, bentonite, kaolin, precipitated calcium carbonate and the attapulgite.
Cycloxaprid water dispersible granule preparation method as second aspect present invention; with cycloxaprid, wetting agent, dispersant, adsorbent, disintegrant, binding agent, stabilizing agent and carrier in proportion behind the mixing; air-flow crushing; make wetting powder, with wetting powder and quantitative water, add in the kneader simultaneously and mediate; make plastic material; send this material to Squeezinggranulator at last, carry out granulation, obtain the water dispersible granules product by dry, screening.
Stable under the storage requirement of cycloxaprid water dispersible granule of the present invention " 2.3 " accelerated storage test method prescribed limit in standard GB/T/T 19136-2003, controlling object comprises the insects such as rice fulgorid, leafhopper.
Embodiment
In order to make purpose of the present invention, technical scheme and advantage clearer and more definite, below in conjunction with example the present invention is done to describe in further detail, describe only limiting to better explain the present invention herein, be not intended to limit the present invention.Embodiment provides the prescription of part cycloxaprid water dispersible granule for the technical staff, and the technical staff can prepare with reference to these prescriptions.
Embodiment 1
By weight percentage cycloxaprid 50%, lauryl sodium sulfate 3%, sodium lignin sulfonate 6%, white carbon 5%, urea 3%, soluble starch 1%, sodium carbonate 3%, diatomite are complemented to 100%; mixed airflow is pulverized; after adding the water kneading; add again and carry out granulation in the comminutor, then drying, sieve to get cycloxaprid water dispersible granule.
Embodiment 2
By weight percentage cycloxaprid 70%, lauryl sodium sulfate 4%, calcium lignosulfonate 7%, white carbon 5%, urea 3%, soluble starch 1%, sodium bicarbonate 5%, kaolin are complemented to 100%; mixed airflow is pulverized; after adding the water kneading; add again and carry out granulation in the comminutor, then drying, sieve to get cycloxaprid water dispersible granule.
Embodiment 3
The cycloxaprid field efficacy is measured:
With the 50% cycloxaprid WG of embodiment 1 with 22.5g a.i./hm
2, 30.0g a.i./hm
2, 37.5ga.i./hm
2Prevent and treat the rice fulgorid in the paddy field, the investigation dispenser after 1 day, 5 days, 15 days, the 30 days control efficiency to rice fulgorid.Investigation result compares with the contrast medicament, and 50% cycloxaprid WG has preferably preventive effect to Brown Planthopper, has long characteristics of lasting period, and to rice safety, the results are shown in Table 1.
Table 1 50% cycloxaprid WG control Brown Planthopper field control effectiveness test result
With 3000,5000,20000 times of controls of the 70% cycloxaprid WG of embodiment 2 dilution grape leafhoppers, after the investigation dispenser 1 day, 3 days, 7 days, 14 days control efficiency.Experiment shows that 70% cycloxaprid WG has higher preventive effect to the grape leafhopper nymph, and in time the preventive effect of each chemicals treatment of prolongation all improves behind the medicine, illustrate that this medicament has preferably lasting effect, and this medicament the results are shown in Table 2 to grape growth safety.
Table 2 70% cycloxaprid WG field efficacy
Claims (7)
1. cycloxaprid water dispersible granule is characterized in that, comprises the active ingredient cycloxaprid, and formulation is water dispersible granules; Take the raw material total amount of cycloxaprid water dispersible granule as 100%, the weight proportion of each raw material is: cycloxaprid 2～90%, wetting agent 1～10%, dispersant 2～15%, adsorbent 1～5%, disintegrant 0～10%, binding agent 1～10%, stabilizing agent 1～10%, all the other are carrier;
Described wetting agent is lauryl sodium sulfate, and described dispersant is lignosulfonates.
2. cycloxaprid water dispersible granule as claimed in claim 1 is characterized in that, described adsorbent is one or more the mixing in diatomite, attapulgite, calcium carbonate, white carbon, thenardite, the avicel cellulose.
3. cycloxaprid water dispersible granule as claimed in claim 1 is characterized in that, described disintegrant is one or more the mixing in urea, ammonium sulfate, calcium chloride, sodium chloride, magnesium chloride and the aluminium chloride.
4. cycloxaprid water dispersible granule as claimed in claim 1 is characterized in that, described binding agent is one or more the mixing in soluble starch, dextrin, gum Arabic and the polyvinyl acetate.
5. cycloxaprid water dispersible granule as claimed in claim 1 is characterized in that, described stabilizing agent is sodium hydroxide, sodium carbonate, sodium bicarbonate, the mixing of one or more in benzoic acid, the citric acid.
6. cycloxaprid water dispersible granule as claimed in claim 1 is characterized in that, described carrier is one or more the mixing in diatomite, white carbon, bentonite, kaolin, precipitated calcium carbonate and the attapulgite.
7. method for preparing cycloxaprid water dispersible granule claimed in claim 1; with cycloxaprid, wetting agent, dispersant, adsorbent, disintegrant, binding agent, stabilizing agent and carrier in proportion behind the mixing; air-flow crushing; make wetting powder, with wetting powder and quantitative water, add in the kneader simultaneously and mediate; make plastic material; send this material to Squeezinggranulator at last, carry out granulation, obtain the water dispersible granules product by dry, screening.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110081047 CN102197808B (en) | 2011-03-31 | 2011-03-31 | Cycloxaprid water dispersible granule and preparation method thereof |
| PCT/CN2012/076299 WO2012130190A1 (en) | 2011-03-31 | 2012-05-30 | Water dispersible cycloxaprid granules and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110081047 CN102197808B (en) | 2011-03-31 | 2011-03-31 | Cycloxaprid water dispersible granule and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102197808A CN102197808A (en) | 2011-09-28 |
| CN102197808B true CN102197808B (en) | 2013-10-30 |
Family
ID=44658998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110081047 Active CN102197808B (en) | 2011-03-31 | 2011-03-31 | Cycloxaprid water dispersible granule and preparation method thereof |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN102197808B (en) |
| WO (1) | WO2012130190A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102197808B (en) * | 2011-03-31 | 2013-10-30 | 上海生农生化制品有限公司 | Cycloxaprid water dispersible granule and preparation method thereof |
| CN102197807A (en) * | 2011-03-31 | 2011-09-28 | 上海生农生化制品有限公司 | Cycloxaprid wettable powder and preparation method thereof |
| CN102197804A (en) * | 2011-03-31 | 2011-09-28 | 上海生农生化制品有限公司 | Cycloxaprid suspending agent and preparation method thereof |
| CN102405918A (en) * | 2011-12-25 | 2012-04-11 | 上海生农生化制品有限公司 | Cycloxaprid water dispersible tablets and preparation method thereof |
| CN102960347A (en) * | 2012-12-14 | 2013-03-13 | 江苏七洲绿色化工股份有限公司 | Bactericidal composition containing prothioconazole and trifloxystrobin |
| CN104082318A (en) * | 2014-07-18 | 2014-10-08 | 江苏省绿盾植保农药实验有限公司 | Composite insecticide containing ethylicin and cycloxaprid and application of composite insecticide |
| CN106472538A (en) * | 2016-10-12 | 2017-03-08 | 佛山迅拓奥科技有限公司 | A kind of cycloxaprid and carbamide compound synergic insecticide |
| CN108323522A (en) * | 2018-04-11 | 2018-07-27 | 佛山市普尔玛农化有限公司 | A kind of novel Pesticidal combination |
| CN114426553B (en) * | 2020-10-16 | 2023-08-01 | 华东理工大学 | Eutectic and solvate of cycloxaprid and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1268290A (en) * | 2000-04-25 | 2000-10-04 | 江苏省农药研究所 | Granulating method of pesticide water-dispersing granules preparation |
| CN1741740A (en) * | 2003-01-23 | 2006-03-01 | 日本曹达株式会社 | Water dispersible granules for agricultural and horticultural use |
| CN1957696A (en) * | 2006-10-20 | 2007-05-09 | 新沂市中港农用化工有限公司 | Water dispersion granules of pesticide, and preparation method |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101747320B (en) * | 2008-12-19 | 2013-10-16 | 华东理工大学 | Dialdehyde-built nitrogen or oxygen-containing heterocyclic compound with insect-killing activity and preparation method |
| CN102093389B (en) * | 2009-12-09 | 2014-11-19 | 华东理工大学 | Duplex and oxygen bridge heterlcyclic ring anabasine compound and preparation method thereof |
| CN102197808B (en) * | 2011-03-31 | 2013-10-30 | 上海生农生化制品有限公司 | Cycloxaprid water dispersible granule and preparation method thereof |
-
2011
- 2011-03-31 CN CN 201110081047 patent/CN102197808B/en active Active
-
2012
- 2012-05-30 WO PCT/CN2012/076299 patent/WO2012130190A1/en active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1268290A (en) * | 2000-04-25 | 2000-10-04 | 江苏省农药研究所 | Granulating method of pesticide water-dispersing granules preparation |
| CN1741740A (en) * | 2003-01-23 | 2006-03-01 | 日本曹达株式会社 | Water dispersible granules for agricultural and horticultural use |
| CN1957696A (en) * | 2006-10-20 | 2007-05-09 | 新沂市中港农用化工有限公司 | Water dispersion granules of pesticide, and preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102197808A (en) | 2011-09-28 |
| WO2012130190A1 (en) | 2012-10-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102197808B (en) | Cycloxaprid water dispersible granule and preparation method thereof | |
| CN101810172B (en) | Insecticidal composition containing fluorin inspect bisamide and monosultap | |
| CN102197807A (en) | Cycloxaprid wettable powder and preparation method thereof | |
| CN102369922B (en) | Pyrazosulfuron water dispersible granule and preparation method thereof | |
| CN105532698A (en) | Composition containing SYP9080 and benzoyl urea pesticide, and application thereof | |
| CN101518242B (en) | Emamectin benzoate-hexaflumuron water dispersible granule and preparation method thereof | |
| CN100588322C (en) | Tebuconazole water dispersible granule and preparation method thereof | |
| CN102217638B (en) | Pesticide composition for preventing and treating plant virus diseases | |
| CN101642105B (en) | Uniconazole water dispersible granules and preparation method thereof | |
| CN102228025A (en) | Pesticide composition containing cytosinpeptidemycin and lentinan | |
| CN101971829B (en) | Chlorantraniliprole and azadirachtin complex water dispersible granule and preparation method thereof | |
| CN101204153A (en) | Triflumizole water dispersant and preparation method thereof | |
| CN102047877A (en) | Cyhalofop-butyl water-dispersible granule and preparation method thereof | |
| CN101731222A (en) | Ethirimol water dispersible granules | |
| CN101485324A (en) | Agricultural insecticide containing flufenoxuron | |
| CN102669138A (en) | Water dispersible granule formulated by azoxystrobin and cymoxanil and preparation method thereof | |
| CN102228036A (en) | Pesticide composition containing strobilurin fungicide | |
| CN104522034A (en) | Compound granule for direct broadcasting and application | |
| CN101971830B (en) | Chlorantraniliprole and rotenone complex insecticidal water dispersible granule and preparation method thereof | |
| CN101167462A (en) | Diniconazole water dispersible granule and preparation method thereof | |
| CN108378062A (en) | A kind of composition pesticide and its application containing beauveria bassiana and metaflumizone | |
| CN103843798A (en) | Pesticide composition containing aureonucleomycin and strobilurin fungicide | |
| CN101167461A (en) | Diniconazole water dispersible granule and preparation method thereof | |
| CN102258048A (en) | Imidacloprid water dispersible granules | |
| CN108402060A (en) | A kind of high-content avermectin water dispersible granules and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee | ||
| CP01 | Change in the name or title of a patent holder |
Address after: Songjiang District Jing Dong Zhen Dong Zhou road 201619 Shanghai City No. 51 Patentee after: Shanghai biochemical products Limited by Share Ltd Patentee after: East China University of Science and Technology Address before: Songjiang District Jing Dong Zhen Dong Zhou road 201619 Shanghai City No. 51 Patentee before: Shengnong Biological-Chemical Products Co., Ltd., Shanghai Patentee before: East China University of Science and Technology |