CN102178808A - Medicine for adjunctively treating prostatic disease - Google Patents
Medicine for adjunctively treating prostatic disease Download PDFInfo
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- CN102178808A CN102178808A CN 201110101366 CN201110101366A CN102178808A CN 102178808 A CN102178808 A CN 102178808A CN 201110101366 CN201110101366 CN 201110101366 CN 201110101366 A CN201110101366 A CN 201110101366A CN 102178808 A CN102178808 A CN 102178808A
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Abstract
The invention provides a medicine for adjunctively treating prostatic diseases, which is a medicament prepared from the following raw materials and pharmaceutically acceptable auxiliary materials in parts by weight: 160-260 parts of sabal extracts, 25-72 parts of pygeum topengii extracts, 20-80 parts of pumpkinseed extracts, 3-20 parts of lycopene and 2-15 parts of zinc. The medicine is used for treating the prostatic diseases by taking the sabal extracts and the pygeum topengii extracts as main raw materials; the synergistic effect is enhanced through the pumpkinseed extracts to play an important role in enhancing the bioavailability of the effectively components of the sabal extracts; the antioxidant ability of organisms and the resistance can be enhanced through the lycopene; and the risks of prostatic cancers is reduced by preventing and improving the prostatic diseases through the lycopene and the zinc; the medicine provided by the invention accords with the traditional Chinese medicine theory and has more scientific formula and more outstanding effect; through clinical verification, the medicine has better curative effect on the prostatic diseases; in addition, the medicine provided by the invention can be taken for a long time without toxic side effect and has the effects of disease prevention and treatment.
Description
Technical field
The present invention relates to a kind of medicine, specifically be meant a kind of medicine of auxiliary treatment prostatosis.
Background technology
Prostatosis is a kind of sickness rate height, the thorny disease of treatment.It generally comprises acute and chronic prostatitis, bacterial prostatitis, prostatic hyperplasia, carcinoma of prostate etc., is puzzlement male's common disease.The common sympton of prostatosis is frequent micturition, urgent micturition, dysurea, drips white, lumbago, even causes sexual dysfunction etc.Prostatosis clinical symptoms complexity, normal easily recurrence.
At present, the main treatment means of prostatosis is medicine and operation etc.But because the special physiological structure of prostate, common drug is difficult to enter its inside through the hard adipose membrane of one deck of prostate coated outside; Moreover because the special pathogeny of prostatosis causes the class of medications poor effect, side effect is very big.And operative treatment not only cost is very high, therapeutic effect is not good yet, and side effect is big, very painful after the treatment.In the tradition Chinese medicine, though many at the effective plant amedica of prostate, corresponding clinical research and excess syndrome effect are more limited, and DeGrain in practice.
At present, doctor trained in Western medicine both domestic and external generally can only play the effect of interim control disease to also not effective especially treatment means of this type of disease and method, can't effect a radical cure fully.The medicine of auxiliary treatment prostatosis can not effectively be cured, can only control disease, delay the degree of symptom.So, by natural galenical carry out nutrition improvement and auxiliary treatment popular in American-European countries, surpass 70% patient and select for use the galenical that has no side effect, do not have drug dependence to improve the symptom of chronic prostatitis and prostatic hyperplasia.Therefore, be necessary to provide a kind of medicine of the prostatosis of auxiliary treatment safely and effectively.
According to scientific research, the natural plant that can be used for treating prostatic hyperplasia has one at least, 20 kind, wherein uses the widest several plant medicine to be Saw Palmetto P.E, pygeumafricaum extract, Semen Cucurbitae extract, lycopene and Semen Sesami Nigrum extract.
Saw Palmetto P.E is rich in various fatty acids and volatile oil, mainly contains linoleic acid, lauric acid, myristic acid, Palmic acid, stearic acid, linolenic acid, cupreol, campesterol, stigmasterol etc.Saw Palmetto P.E has the inhibition prostatic hyperplasia, effects such as antibiotic, vasoconstrictive, enhancing muscle, anti-stick film, diuresis, the activity that can suppress 5, testosterone in the prostata tissue is reduced to the conversion of dihydrotestosterone, thereby suppress the propagation of prostatic cell and significantly improve prostatic hyperplasia patient's urethra infraction symptom, benign prostatic hyperplasia is had good curative effect, and have the effect of resistance prostatitis disease.Though Saw Palmetto P.E is a natural prostate hyperplasia Remedies evident in efficacy, its therapeutic effect takes effect slowly, and the treatment total effective rate is 84%.
The pygeumafricaum extract has the effect of alleviating prostatitis and prostatic hyperplasia, and its three kinds of contained main active are:
A. plant sterol (as cupreol): can antiinflammatory, can reduce prostatic hyperplasia patient's prostaglandin level;
B. pentacyclic triterpenoid (comprising ursolic acid and oleic acid): help inflammation-inhibiting, alleviate prostatic swelling, increase complete venule and blood capillary;
C. ferulic acid ester (the pure and mild octacosanol of docosane): help to remove any cholesterol of following prostatauxe and piling up in the prostate.
The Semen Cucurbitae extract contains abundant unsaturated fatty acid, aminoacid, vitamin and carotene isoreactivity nutritional labeling and abundant zinc element, and prostate is had health-care effect.The fatty acid that enriches in the Semen Cucurbitae extract can make prostate keep good function; Contained active component can be eliminated the swelling at prostatitis initial stage, prevents the effect of carcinoma of prostate simultaneously in addition; Contain abundant zinc, can replenish the human body deficiency, the control prostate hyperplasia.The Semen Cucurbitae extract has alleviates prostatitis and the pharmacological action for the treatment of benign prostatic hyperplasia, but Semen Cucurbitae uses curative effect relatively poor separately.Semen Sesami Nigrum extract has been the prevention mitigation too, uses curative effect also relatively poor separately.
Lycopene is the strongest antioxidant of occurring in nature, and its antioxidation is 2 times of beta-carotene, and 100 times of VE have the ability of extremely strong removing free radical.Studies show that often consumption of lycopene can prevent benign prostate hyperplasia, can help prevention and improve diseases of urinary system such as prostatic hyperplasia, prostatitis, can help to reduce the carcinoma of prostate risk.Tomato sauce is than the more effective minimizing risk of prostate cancer of any meals pattern (physical exertion is drunk and the use of olive oil for diet variable such as Body Mass Index, smoking).
Recently, according to professor Heston of U.S. Saint Louis University of Washington, in the body of prostatitis patient, zinc content has only ordinary person's 1/10, and the zinc in inflammation itself and the prostatic fluid is closely bound up.In the chronic bacterial prostatitis patient, the composition of zinc significantly descends, and antimicrobial ability also dies down or disappears.So zinc salt has the defense mechanism of nature, the reproduction that can resist up property (the refer to prostate above organ) urinary system that oozes infects.Zinc will be higher than independent use vitamin C or E on the preventive effect of carcinoma of prostate.And zinc is the element of at least 70 kinds of ferment in the body, is that synthetic protein institute is essential, can improve immunity, antioxidation and aging resistance.Zinc combines with peroxide distortion ferment SOD, can remove free free radical in the body, reduces the cancer incidence rate.
Because the pathology of prostatosis is extremely complicated, if use these plant amedica separately, not only uses curative effect relatively poor, and patient is differed suit the remedy to the case surely, effectively control disease.
Summary of the invention
The objective of the invention is at the deficiencies in the prior art, a kind of medicine of auxiliary treatment prostatosis is provided, nontoxic for patient can be taken for a long time to health, and effective disease controlling.
The present invention adopts following technical scheme to realize: a kind of medicine of auxiliary treatment prostatosis, the medicament of being made by the raw material and the pharmaceutically useful adjuvant of following weight portion: 160～260 parts of Saw Palmetto P.Es, 25～75 parts of pygeumafricaum extracts, 20～80 parts of Semen Cucurbitae extracts, 3～20 parts of lycopenes, 2～15 parts on zinc.
A kind of medicine of auxiliary treatment prostatosis, the medicament of making by the raw material and the pharmaceutically useful adjuvant of following weight portion: 160 parts of Saw Palmetto P.Es, 25 parts of pygeumafricaum extracts, 20 parts of Semen Cucurbitae extracts, 10 parts of lycopenes, 3 parts on zinc.
Preferably, described Saw Palmetto P.E is selected from the Saw palmetto extract, and the pygeumafricaum extract is selected from the prunus africana extract.Saw palmetto extract and prunus africana extract are the commercially available prod.
Among the present invention, described medicament is soft capsule or tablet.
Among the present invention, described pharmaceutically useful adjuvant is several mixture in soybean oil, soybean phospholipid, glycerol, the gelatin.
Preparation method: with Saw Palmetto P.E, pygeumafricaum extract, Semen Cucurbitae extract, lycopene and zinc is that major ingredient is mixed in proportion, with soybean oil, soybean phospholipid, glycerol, gelatin is adjuvant, makes soft capsule preparation through batching, colloidal sol, pelleting, drying.
Saw Palmetto P.E is the No.1 natural plant food of consistent anti-prostatic hyperplasia of generally acknowledging, the long-term edible prostate of blocking is urged the synthetic of the hypertrophy factor (dihydrotestosterone), hypertrophy capable of blocking, and short its retraction.But the effect after Saw Palmetto P.E is edible is relatively slow, needs 3 months even just shows the effect of improving to urinary tract symptom half a year.In order effectively to remedy this defective, in Saw Palmetto P.E, add the pygeumafricaum extract because the pygeumafricaum extract effect aspect antiinflammatory, diuresis is comparatively outstanding comparatively speaking, it is also very fast relatively to take effect.Simultaneously, lycopene can strengthen health and improve oxidation resistance, improves immunity, also can play acceleration for the alleviation of symptom.So the medicine of auxiliary treatment prostatosis of the present invention can take effect fast, can play treating both the principal and secondary aspects of a disease if just adhere to taking, the effect of efficient rehabilitation.
The present invention takes into full account the demand that the prostate patient " controls, supports, protects " three aspects, " controlling " mainly be unable by Saw Palmetto P.E and pygeumafricaum extract to prostate patient's frequent micturition, urgent micturition, urine, can not urinate, the improvement of symptom such as urine retention embodies; " support " mainly is to the reparation of prostatic cell, the maintenance of organ, and to the reparation of function of male with promote and embody by Saw Palmetto P.E and Semen Cucurbitae extract; " protect " mainly be by lycopene antioxidation, remove free radical, the effect that improves immunity, anti-cancer embodies.This prescription not only has clear improvement for chronic prostate personage's daily symptom, can improve its quality of life, and can also effectively prevent the generation of carcinoma of prostate.
The present invention meets traditional traditional Chinese medical science " monarch " theory, and in this prescription, " monarch " medicine is a Saw Palmetto P.E, and " minister " medicine is the pygeumafricaum extract, and " assistant " medicine is Semen Cucurbitae extract and zinc, and " making " medicine is a lycopene.Saw Palmetto P.E plays main therapeutical effect, and the pygeumafricaum extract has overcome the independent use Saw Palmetto P.E slow deficiency that takes effect ", auxiliary monarch drug is strengthened treatment, and Saw Palmetto P.E and pygeumafricaum extract merge and use therapeutic effect better.Among the present invention the two has been carried out compatibility,, its content has been carried out suitable minimizing simultaneously according to Chinese's body constitution characteristics.In addition, also add the Semen Cucurbitae extract,,, added a certain amount of zinc simultaneously in view of the extremely low characteristics of zinc content in the prostate patient body to strengthen cooperative effect; The health body constitution of considering middle-aged and elderly people a little less than, disease risk is more, adds lycopene, the enhancing body oxidation resistance improves resistance.
Serenoa repens really is American Indian's a food, and prunus africana is African a kind of resources of Chinese medicinal herb that often has, and Semen Cucurbitae is the snack that had deep love for by the people, and zinc is " flower of life " that is widely known by the people, and lycopene is " a plant gold ".The selected raw material of the present invention is experiences all sorts of checking, safe and harmless medicine food dual purpose plant and dietary supplement.
Beneficial effect of the present invention: the present invention is used for the treatment of prostatosis based on Saw Palmetto P.E and pygeumafricaum extract; Strengthen cooperative effect with the Semen Cucurbitae extract, the bioavailability that improves the Saw Palmetto P.E effective ingredient plays an important role; With lycopene enhancing body oxidation resistance, improve resistance, with lycopene and zinc prevention and improve prostatosis, reduce risk of prostate cancer.The present invention meets theory of Chinese medical science, the science more of filling a prescription, and effect is more remarkable.Through clinical verification, this medicine has curative effect preferably to prostatosis.The present invention has no side effect, and can take the effect of have diseases prevention, curing the disease for a long time.
The specific embodiment
Below further specify the present invention by specific embodiment:
Embodiment 1
The medicine of auxiliary treatment prostatosis of the present invention is made by the raw material of following weight portion: Saw palmetto extract 160mg, prunus africana extract 25mg, Semen Cucurbitae extract 20mg, lycopene 10mg, zinc 3mg.
Preparation method: with Saw palmetto extract, prunus africana extract, Semen Cucurbitae extract, lycopene and zinc is that major ingredient is mixed in proportion, with soybean oil, soybean phospholipid, glycerol, gelatin is adjuvant, makes soft capsule preparation through batching, colloidal sol, pelleting, drying.
Usage and dosage: every day twice, each soft capsule, oral.
Embodiment 2
The medicine of auxiliary treatment prostatosis of the present invention is made by the raw material of following weight portion: Saw palmetto extract 180mg, prunus africana extract 30mg, Semen Cucurbitae extract 30mg, lycopene 15mg, zinc 5mg.
Preparation method is identical with embodiment 1.
Usage and dosage: every day twice, each soft capsule, oral.
Embodiment 3
The medicine of auxiliary treatment prostatosis of the present invention is made by the raw material of following weight portion: Saw palmetto extract 160mg, prunus africana extract 25mg, Semen Cucurbitae extract 20mg, lycopene 3mg, zinc 2mg.
Preparation method is identical with embodiment 1.
Usage and dosage: every day twice, each soft capsule, oral.
Embodiment 4
The medicine of auxiliary treatment prostatosis of the present invention is made by the raw material of following weight portion: Saw palmetto extract 260mg, prunus africana extract 75mg, Semen Cucurbitae extract 80mg, lycopene 20mg, zinc 15mg.
Preparation method is identical with embodiment 1.
Usage and dosage: every day twice, each soft capsule, oral.
The clinical efficacy checking:
1. the present invention carries out clinical observation to 150 patients.Instructions of taking is each 1 sooner or later of every day, and the cycle of taking was 6 weeks.
(1) efficacy assessment standard:
Produce effects: clinical symptoms disappears substantially, and international prostate gland symptoms scoring significantly reduces, and the bladder residual urine significantly reduces, and the urine flow rate obviously improves;
Effectively: clinical symptoms takes a turn for the better, and international prostate gland symptoms scoring descends, and residual urine reduces, and the urine flow rate improves;
Invalid: clinical symptoms is preceding identical with treatment, and international prostate gland symptoms scoring and residual urine do not have improvement.
(2) therapeutic effect:
Clinical treatment produce effects 60 examples account for 40%; Effective 80 examples account for 53% invalid 10 examples, account for 7%, total effective rate 93%.
2. the cycle of taking effect to medicine of the present invention studies show that: 71% chronic prostate patient just had obvious effects at preceding 15 days that take, and showed the most intuitively in the obvious minimizing of the number of times of getting up in the night to urinate.Such as, 5～6 times take of getting up in the night to urinate evening just is kept to about 2 times about 10 days; Not get up in the night to urinate 2～3 times can not get up in the night to urinate substantially.
3. the present invention takes medicine of the present invention respectively to 100 routine patients and contrasts with using separately the effect of Saw Palmetto P.E, 6 weeks of the course of treatment, dosage: 2 times on the one, one time 1～2.Its statistical result is as shown in table 1.
Table 1:
| The result | Medicine of the present invention | Saw Palmetto P.E |
| Produce effects | 40％ | 38％ |
| Effectively | 53％ | 46％ |
| Invalid | 7％ | 16％ |
| Total effective rate | 93％ | 84％ |
Saw Palmetto P.E has therapeutic effect to prostatic hyperplasia, nonbacterial prostatitis, but total effective rate is lower than composition of medicine of the present invention.
Claims (5)
1. the medicine of an auxiliary treatment prostatosis, the medicament of making by the raw material and the pharmaceutically useful adjuvant of following weight portion:
2. the medicine of auxiliary treatment prostatosis according to claim 1 is characterized in that, the medicament that it is made by the raw material and the pharmaceutically useful adjuvant of following weight portion:
3. the medicine of auxiliary treatment prostatosis according to claim 1 and 2 is characterized in that: described Saw Palmetto P.E is selected from the Saw palmetto extract, and the pygeumafricaum extract is selected from the prunus africana extract.
4. the medicine of auxiliary treatment prostatosis according to claim 1 and 2 is characterized in that: described medicament is soft capsule or tablet.
5. the medicine of auxiliary treatment prostatosis according to claim 1 and 2 is characterized in that: described pharmaceutically useful adjuvant is several mixture in soybean oil, soybean phospholipid, glycerol, the gelatin.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201110101366 CN102178808A (en) | 2011-04-22 | 2011-04-22 | Medicine for adjunctively treating prostatic disease |
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| CN 201110101366 CN102178808A (en) | 2011-04-22 | 2011-04-22 | Medicine for adjunctively treating prostatic disease |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793173A (en) * | 2012-09-05 | 2012-11-28 | 谷延明 | Pumpkin seed cake healthcare product and production method |
| CN103690727A (en) * | 2013-12-26 | 2014-04-02 | 福建金源泉科技发展有限公司 | Sabal and blackcurrant composition and application thereof |
| CN105106520A (en) * | 2015-10-06 | 2015-12-02 | 常州亚当生物技术有限公司 | Healthcare product |
| CN105747172A (en) * | 2016-02-23 | 2016-07-13 | 庆阳中庆农产品有限公司 | Jinfansu composition containing green pumpkin seed endosperm, and preparation method of Jinfansu composition |
| CN105796803A (en) * | 2014-12-30 | 2016-07-27 | 青岛加云华海健康科技有限公司 | Traditional Chinese medicine composition for treating and preventing prostatic diseases and its preparation method and use |
| CN106421245A (en) * | 2016-09-29 | 2017-02-22 | 福建农林大学 | Compound plant-caused transdermal patch for treating prostatic hyperplasia and preparation method thereof |
| CN108813059A (en) * | 2018-05-04 | 2018-11-16 | 刀海林 | A kind of coffee type edible health product and preparation method thereof |
| CN114177238A (en) * | 2022-01-11 | 2022-03-15 | 锦州拾正生物科技有限公司 | Composition for preventing or treating prostatic hyperplasia and preparation method thereof |
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| CN1736396A (en) * | 2004-08-16 | 2006-02-22 | 新疆特丰药业股份有限公司 | Compound lycopene formulation for men and preparation process thereof |
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2011
- 2011-04-22 CN CN 201110101366 patent/CN102178808A/en active Pending
Patent Citations (1)
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| CN1736396A (en) * | 2004-08-16 | 2006-02-22 | 新疆特丰药业股份有限公司 | Compound lycopene formulation for men and preparation process thereof |
Non-Patent Citations (1)
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| 《中国医药报》 20030213 徐铮奎 良性前列腺肥大症植物疗法新进展 1-5 , 2 * |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793173A (en) * | 2012-09-05 | 2012-11-28 | 谷延明 | Pumpkin seed cake healthcare product and production method |
| CN102793173B (en) * | 2012-09-05 | 2014-01-22 | 谷延明 | Pumpkin seed cake healthcare product and production method |
| CN103690727A (en) * | 2013-12-26 | 2014-04-02 | 福建金源泉科技发展有限公司 | Sabal and blackcurrant composition and application thereof |
| CN103690727B (en) * | 2013-12-26 | 2016-02-24 | 福建金源泉科技发展有限公司 | A kind of sabal Ribes nigrum L. compositions and application thereof |
| CN105796803A (en) * | 2014-12-30 | 2016-07-27 | 青岛加云华海健康科技有限公司 | Traditional Chinese medicine composition for treating and preventing prostatic diseases and its preparation method and use |
| CN105106520A (en) * | 2015-10-06 | 2015-12-02 | 常州亚当生物技术有限公司 | Healthcare product |
| CN105747172A (en) * | 2016-02-23 | 2016-07-13 | 庆阳中庆农产品有限公司 | Jinfansu composition containing green pumpkin seed endosperm, and preparation method of Jinfansu composition |
| CN106421245A (en) * | 2016-09-29 | 2017-02-22 | 福建农林大学 | Compound plant-caused transdermal patch for treating prostatic hyperplasia and preparation method thereof |
| CN108813059A (en) * | 2018-05-04 | 2018-11-16 | 刀海林 | A kind of coffee type edible health product and preparation method thereof |
| CN114177238A (en) * | 2022-01-11 | 2022-03-15 | 锦州拾正生物科技有限公司 | Composition for preventing or treating prostatic hyperplasia and preparation method thereof |
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Application publication date: 20110914 |