CN102145063B

CN102145063B - Traditional Chinese medicine for treating thrombocytopenic purpura

Info

Publication number: CN102145063B
Application number: CN201110069633A
Authority: CN
Inventors: 王秋芳
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-03-23
Filing date: 2011-03-23
Publication date: 2012-09-19
Anticipated expiration: 2031-03-23
Also published as: CN102145063A

Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for treating thrombocytopenic purpura. The traditional Chinese medicine is prepared from liquoric root, weeping forsythia, sophora flower, root of red-rooted salvia, cuttlebone, sinkiang arnebia root, persimmon leaf, Chinese date, hairyvein agrimonia herb and bud, notoginseng root, bark of tree peony root, tortoise shell, Chinese arborvitae twig, gardenia jasminoides, buffalo horn, buckwheat leaf and peanut sead-coat which serve as active raw materials according to a certain weight ratio. The traditional Chinese medicine is easy to prepare, has a good absorption effect, an obvious curative effect and high safety, does not have side effect, and is favorable for relieving symptoms of patients in time.

Description

The Chinese medicine of treatment thrombocytopenic purpura

(1) technical field

The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicine of treating thrombocytopenic purpura.

(2) background technology

Thrombocytopenic purpura be with PA hemorrhage in common a kind of, clinical manifestation is dermatorrhagia, mucosal bleeding, visceral hemorrhage, disappear the continuity several months now during purpura, the look asthenia, cardiopalmus is breathed hard, giddy is dizzy, shallow complexion.Lab testing: platelet is at 10,000～50,000/mm ³Between fluctuation, the bleeding time prolongs, clot retraction is bad, antiplatelet antibody is positive; Purpura is differed in size, and shade differs, and can merge in flakes; Generally in a few days, disappear gradually; But can show effect repeatedly, the treatment of primary disease with the control over bleeding phenomenon, to reduce hematoblastic destruction, improve hematoblastic generation situation be main means, though doctor trained in Western medicine can be stopped blooding as early as possible; But be difficult to eliminate the blood stasis ecchymosis, can't effect a radical cure.

Theory of Chinese medical science thinks that this disease is by due to the taste imbalance of YIN and YANG.Existing commercially available Chinese medicine is because of existing the human body individual variation bigger, and the somebody is suitable for, and the somebody then is difficult to be suitable for, even does not have effect, therefore, is difficult to generally obtain ideal therapeutic effect.

(3) summary of the invention

The present invention provides a kind of Chinese medicine of preparing treatment thrombocytopenic purpura simple, evident in efficacy in order to remedy the deficiency of prior art.

The present invention realizes through following technical scheme:

A kind of Chinese medicine of treating thrombocytopenic purpura, its active component is made up of the raw material of following parts by weight:

6～10 parts in Radix Glycyrrhizae, 6～12 parts of Fructus Forsythiaes, 4～10 parts in Flos Sophorae, 4～10 parts of Radix Salviae Miltiorrhizaes, 6～12 parts of Endoconcha Sepiaes, 3～9 parts of Radix Arnebiae (Radix Lithospermi)s, 3～9 parts of Folium Kaki, 6～12 parts in Fructus Jujubae, 6～12 parts of Herba Agrimoniaes, 3～9 parts of Radix Notoginseng, 3～9 parts of Cortex Moutans, 1～3 part of Carapax Et Plastrum Testudinis, 6～12 parts of Cacumen Platycladis, 4～10 parts of Fructus Gardeniaes, 9～15 parts of Cornu Bubalis, 4～10 parts of buckwheat leafs, 9～15 parts of Testa arachidis hypogaeaes.

The weight proportion of its preferred each active component is:

8 parts in Radix Glycyrrhizae, 9 parts of Fructus Forsythiaes, 7 parts in Flos Sophorae, 7 parts of Radix Salviae Miltiorrhizaes, 9 parts of Endoconcha Sepiaes, 6 parts of Radix Arnebiae (Radix Lithospermi)s, 6 parts of Folium Kaki, 9 parts in Fructus Jujubae, 9 parts of Herba Agrimoniaes, 6 parts of Radix Notoginseng, 6 parts of Cortex Moutans, 2 parts of Carapax Et Plastrum Testudiniss, 9 parts of Cacumen Platycladis, 7 parts of Fructus Gardeniaes, 12 parts of Cornu Bubalis, 7 parts of buckwheat leafs, 12 parts of Testa arachidis hypogaeaes.

Chinese medicine according to the invention is decoction.After each raw material cleaned up, being decocted in water for oral dose, every day potion, decoction being taken warmly at twice.

The pharmaceutical characteristic of each activated feedstock is following:

Radix Glycyrrhizae: with middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.Give birth to controlling laryngopharynx swelling and pain carbuncle pyogenic infections from tumour or sore, infantile carbuncle, and medicine, things poisoning;

Fructus Forsythiae: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Cure mainly anemopyretic cold, damp disease, pyretic stranguria urine retention, carbuncle, toxic swelling, scrofula, goiter, sore throat;

Flos Sophorae: cooling blood for hemostasis, liver heat removing and eyesight improving.Cure mainly discharging fresh blood stool, the hemorrhoid hematochezia, dysentery with red and white feces, stranguria with blood, metrorrhagia is spitted blood, epistaxis, sore swollen toxin, but and prevention of stroke;

Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the removing heat from blood eliminating carbuncle.Cure mainly menoxenia, dysmenorrhea, amenorrhea ， lumps in the chest and abdomen, pyretic arthralgia swells and ache, dysphoria, vexed insomnia;

Endoconcha Sepiae: astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, removing dampness is held back skin ulcer.Cure mainly haematemesis, hematemesis, metrorrhagia is had blood in stool, epistaxis, wound hemorrhage, emission due to deficiency of the kidney spermatorrhea;

Radix Arnebiae (Radix Lithospermi): removing heat from blood and promoting blood circulation, detoxifcation rash.Cure mainly haematemesis, epistaxis, hematuria, purpura, macule, measles, jaundice, carbuncle is scalded;

Folium Kaki: relieving cough and relieving asthma, promote the production of body fluid hemostasis.Cure mainly cough with asthma, quench one's thirst and various internal hemorrhage ecthyma;

Fructus Jujubae: tonifying the spleen and stomach, replenishing QI and blood, tranquilizing mind transfers battalion to defend, and the property of medicine.Cure mainly weakness of the spleen and stomach, insufficiency of vital energy and blood, fatigue and weakness, palpitation and insomnia, woman hysteria, disharmony of nutrient QI with defensive QI;

Herba Agrimoniae: astringing to arrest bleeding, removing food stagnancy dysentery relieving, removing toxic substances and promoting subsidence of swelling.Cure mainly spitting of blood, spit blood, epistaxis, hematuria is had blood in stool, metrorrhagia and traumatic hemorrhage, diarrhoea, dysentery;

Radix Notoginseng: hemostasis dissipating blood stasis, subduing swelling and relieving pain.Cure mainly leaf blood, hemoptysis, urine to, have blood in stool, dysentery, metrorrhagia ， mass in the abdomen amass piece, the blood stasis amenorrhea, dysmenorrhea, puerperal, the stasis of blood stagnate to be suffered from abdominal pain, sore, carbuncle and painful swelling;

Cortex Moutan: clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Cure mainly the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea ， mass in the abdomen, carbuncle sore tumefacting virus;

Carapax Et Plastrum Testudinis: nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone, heart tonifying and tranquilizing, controlling nocturnal emission with astringent drugs hemostasis.Cure mainly deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat is had a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, wriggling of the limbs;

Cacumen Platycladi: cooling blood for hemostasis, expelling phlegm for arresting cough, the detoxifcation of dispeling the wind.Cure mainly haematemesis, epistaxis, hematuria, dysentery, hemorrhoidal hamorrhage, metrorrhagia, cough with copious phlegm, rheumatic arthralgia;

Fructus Gardeniae: pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.It is vexed to cure mainly calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood epistaxis, dysentery, hematuria;

Cornu Bubali: heat clearing away, detoxifcation, removing heat from blood, arresting convulsion.Cure mainly the calentura headache, unconsciousness due to high fever is sent out the speckle dermexanthesis, haematemesis, epistaxis, stagnant heat jaundice, infantile convulsion and laryngopharynx swelling and pain, aphtha of the mouth and tongue;

Buckwheat leaf: sharp knowledge, the therapeutic method to keep the adverse QI flowing downwards, hemostasis, blood pressure lowering.Cure mainly the eyes narco, tinnitus is hard of hearing, belch, purpura, hypertension;

Testa arachidis hypogaeae: hemostasis, dissipating blood stasis, detumescence.Cure mainly hemophilia, hemophilioid disease, constitutional and secondary thrombocytopenic purpura, hepatopathy is hemorrhage, multiple internal hemorrhage such as postoperative hemorrhage.

In the prescription, Fructus Forsythiae, Cacumen Platycladi, Fructus Gardeniae, Cornu Bubali are mainly used in heat-clearing and toxic substances removing, pathogenic fire purging relieving restlessness, removing heat from blood arresting convulsion; Add and join Flos Sophorae, Endoconcha Sepiae, Folium Kaki, Herba Agrimoniae, be used for cooling blood for hemostasis, liver heat removing and eyesight improving, relieving gastric hyperacidity to alleviate stomachache, removing dampness and hold back skin ulcer; Join Radix Arnebiae (Radix Lithospermi), Radix Notoginseng, Cortex Moutan, Testa arachidis hypogaeae again, be mainly used in blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, subduing swelling and relieving pain; Join Radix Salviae Miltiorrhizae, Fructus Jujubae, Carapax Et Plastrum Testudinis, buckwheat leaf again, be used for strengthening the spleen and nourishing the stomach, reinforcing the kidney to strengthen the bone, nourishing YIN for suppressing the hyperactive YANG, dredging the meridian, microcirculation improvement; Add at last and join Radix Glycyrrhizae, be used for heat-clearing and toxic substances removing, alleviate pain relieving, coordinating the actions of various ingredients in a prescription, the toxicity of cushion and strong.

The present invention is based on pathogenetic understanding and the Therapeutic Principle of China's Chinese medicine, with reference to the modern pharmacological research achievement, from medical treasure-house, filter out heat clearing away, detoxifcation, promoting blood circulation to remove blood stasis, removing heat from blood, nourish blood, the crude drug of hemostasis, line water detumescence thrombocytopenic purpura; By the theory of Chinese medical science prescription, make its performance clearing away heat and cooling blood, the hemostasis dissipating rashes; Promoting blood circulation to remove blood stasis; Microcirculation improvement, dredging the meridian, effects such as eliminate pain.

Clinical observation:

(1) clinical data

The inventor carries out clinical observation treatment to 43 routine thrombocytopenic purpura patients in 2005 so far.

(2) Therapeutic Method

After raw material of the present invention cleaned up, being decocted in water for oral dose, every day potion, decoction being taken warmly at twice.Calculate treatment time according to the conditions of patients weight, patients with mild was taken about 6 months, and the severe case serve on 2 years and can fully recover.

(3) curative effect determinate standard

Cure: symptoms such as blood stasis, ecchymosis, muscle and neuralgia, anasarca, inconvenient activity all disappear, and tracing observation does not have recurrence in two years.

Produce effects: symptoms such as muscle and neuralgia, anasarca, inconvenient activity all disappear, and still have a small amount of ecchymosis to exist, but all have not big harm, and do not influence living and studying.

Effectively: anasarca is eliminated, and activity but still has blood stasis, ecchymosis to exist freely, and muscle and nerve also pain can occur frequently.

Invalid: DeGrain.

(4) clinical effectiveness

Clinical cure 31 examples (72.09%), produce effects 6 examples (13.96%), effective 4 examples (9.30%), invalid 2 examples (4.65%), total effective rate is 98.42%.

The present invention prepares simply, and good absorbing effect is evident in efficacy, has no side effect, and is safe, helps sufferer and in time alleviates condition of illness.

(4) specific embodiment

Embodiment 1:

Extracting liquorice 6g, Fructus Forsythiae 6g, Flos Sophorae 4g, Radix Salviae Miltiorrhizae 4g, Endoconcha Sepiae 6g, Radix Arnebiae (Radix Lithospermi) 3g, Folium Kaki 3g, Fructus Jujubae 6g, Herba Agrimoniae 6g, Radix Notoginseng 3g, Cortex Moutan 3g, Carapax Et Plastrum Testudinis 1g, Cacumen Platycladi 6g, Fructus Gardeniae 4g, Cornu Bubali 9g, buckwheat leaf 4g, Testa arachidis hypogaeae 9g; Above-mentioned raw materials is cleaned up the fried one-tenth decoction of water.

Usage and dosage: be decocted in water for oral dose, every day potion, decoction being taken warmly at twice.

Embodiment 2:

Extracting liquorice 10g, Fructus Forsythiae 12g, Flos Sophorae 10g, Radix Salviae Miltiorrhizae 10g, Endoconcha Sepiae 12g, Radix Arnebiae (Radix Lithospermi) 9g, Folium Kaki 9g, Fructus Jujubae 12g, Herba Agrimoniae 12g, Radix Notoginseng 9g, Cortex Moutan 9g, Carapax Et Plastrum Testudinis 3g, Cacumen Platycladi 12g, Fructus Gardeniae 10g, Cornu Bubali 15g, buckwheat leaf 10g, Testa arachidis hypogaeae 15g; Above-mentioned raw materials is cleaned up the fried one-tenth decoction of water.

Embodiment 3:

Extracting liquorice 8g, Fructus Forsythiae 9g, Flos Sophorae 7g, Radix Salviae Miltiorrhizae 7g, Endoconcha Sepiae 9g, Radix Arnebiae (Radix Lithospermi) 6g, Folium Kaki 6g, Fructus Jujubae 9g, Herba Agrimoniae 9g, Radix Notoginseng 6g, Cortex Moutan 6g, Carapax Et Plastrum Testudinis 2g, Cacumen Platycladi 9g, Fructus Gardeniae 7g, Cornu Bubali 12g, buckwheat leaf 7g, Testa arachidis hypogaeae 12g; Above-mentioned raw materials is cleaned up the fried one-tenth decoction of water.

Claims

1. Chinese medicine of treating thrombocytopenic purpura; It is characterized by, its active component is made up of the raw material of following parts by weight: 6～10 parts in Radix Glycyrrhizae, 6～12 parts of Fructus Forsythiaes, 4～10 parts in Flos Sophorae, 4～10 parts of Radix Salviae Miltiorrhizaes, 6～12 parts of Endoconcha Sepiaes, 3～9 parts of Radix Arnebiae (Radix Lithospermi)s, 3～9 parts of Folium Kaki, 6～12 parts in Fructus Jujubae, 6～12 parts of Herba Agrimoniaes, 3～9 parts of Radix Notoginseng, 3～9 parts of Cortex Moutans, 1～3 part of Carapax Et Plastrum Testudinis, 6～12 parts of Cacumen Platycladis, 4～10 parts of Fructus Gardeniaes, 9～15 parts of Cornu Bubalis, 4～10 parts of buckwheat leafs, 9～15 parts of Testa arachidis hypogaeaes.

2. the Chinese medicine of treatment thrombocytopenic purpura according to claim 1; It is characterized by, its active component is made up of the raw material of following parts by weight: 8 parts in Radix Glycyrrhizae, 9 parts of Fructus Forsythiaes, 7 parts in Flos Sophorae, 7 parts of Radix Salviae Miltiorrhizaes, 9 parts of Endoconcha Sepiaes, 6 parts of Radix Arnebiae (Radix Lithospermi)s, 6 parts of Folium Kaki, 9 parts in Fructus Jujubae, 9 parts of Herba Agrimoniaes, 6 parts of Radix Notoginseng, 6 parts of Cortex Moutans, 2 parts of Carapax Et Plastrum Testudiniss, 9 parts of Cacumen Platycladis, 7 parts of Fructus Gardeniaes, 12 parts of Cornu Bubalis, 7 parts of buckwheat leafs, 12 parts of Testa arachidis hypogaeaes.

3. the Chinese medicine of treatment thrombocytopenic purpura according to claim 1 and 2 is characterized in that: said Chinese medicine is decoction.