CN102133370B - Traditional Chinese medicine pelvic inflammatory disease clearing decoction for curing chronic pelvic inflammatory diseases - Google Patents
Traditional Chinese medicine pelvic inflammatory disease clearing decoction for curing chronic pelvic inflammatory diseases Download PDFInfo
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- CN102133370B CN102133370B CN2011100490967A CN201110049096A CN102133370B CN 102133370 B CN102133370 B CN 102133370B CN 2011100490967 A CN2011100490967 A CN 2011100490967A CN 201110049096 A CN201110049096 A CN 201110049096A CN 102133370 B CN102133370 B CN 102133370B
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Abstract
The invention discloses a traditional Chinese medicine pelvic inflammatory disease clearing decoction for curing chronic pelvic inflammatory diseases. The decoction is prepared by selecting rhizoma curcumae, frankincense, rhizoma atractylodis, codonopsis pilosula, safflower, cinnamon, rhizoma cyperi, sargentgloryvine stem, patrinia scabiosaefolia fisch, radix paeoniae alba, radix bupleuri, garden balsam stem, ginseng, angelica and radix paeoniae rubra according to pathogenesis of chronic pelvic inflammatory diseases. The decoction indicates the effects of clearing heat and detoxicating, clearing damp and promoting blood flow, and has the function of nourishing body with proper dosing. The curing effect is good, the curing rate can achieve 62.03% and the total efficiency achieves 98.15% by the clinical observation, and the curing cost is low, and the decoction is worthy of promotion and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, relate in particular to a kind of Chinese medicine 'Penyanjing ' of treating chronic pelvic inflammatory disease.
Background technology
Chronic pelvic inflammatory disease is common gynecological disease, frequently-occurring disease, sickness rate 30%～60%, and its sickness rate has the trend that increases gradually in recent years.Show as mainly that hypogastric region weigh down to expand, pain and lumbosacral region ache, menoxenia, leucorrhoea grow in quantity, matter is thick and yellow or held blood under the arm, and abnormal flavour is arranged, red tongue or dark red, yellow fur or greasy, stringy and thready pulse.Its course of disease of this cause of disease is long, the state of an illness is obstinate, relapse rate is high and had a strong impact on women's physical and mental health and quality of life.Mostly this disease is that the inflammation of pelvic connective tissue disease that causes behind the pathogenic infection sexually revises, and does not still have specific treatment, and at present the employing with the antibiotic is main therapy more; Not only the course of treatment long, and be prone to produce drug resistance, upset organismic internal environment; Cause recurrence when body's immunity descends; Even carrying out property increases the weight of, the clinical treatment lack of specific, and curative effect is not fully up to expectations.Though the Chinese medicine of treatment chronic pelvic inflammatory disease is more, all has the unfavorable problem of therapeutic effect.
Summary of the invention
The purpose of this invention is to provide a kind of scorching clean decoction of Chinese medicine basin of treating chronic pelvic inflammatory disease, it has the good advantage of therapeutic effect.Motherland's medical science thinks, the sick position of chronic pelvic inflammatory disease is at pelvic cavity, and its cause of disease is many by evil poison or damp and hot, through pudendum up and be against appoint, uterus; So that pathogen stays the notes or the stasis of blood to stagnate in this one, and QI-blood circulation is obstructed, the infringement pelvic tissue; Or the course of disease is with the passing of time, protracted course of disease, and the adhesion hypertrophy forms note of the ancient Chinese abdominal mass enclosed mass.So blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis are the primary rules of treatment primary disease.
The objective of the invention is to realize through following technical scheme; The scorching clean decoction of the Chinese medicine basin of this treatment chronic pelvic inflammatory disease is processed by the Chinese medicine of following weight fraction: Rhizoma Curcumae 3-7 branch, Olibanum 3-7 branch; Rhizoma Atractylodis 1-5 branch, Radix Codonopsis 3-5 branch, Flos Carthami 3-5 branch, Cortex Cinnamomi 1-5 branch, Rhizoma Cyperi 1-3 branch, lose slurry careless 3-5 branch, Radix Paeoniae Alba 3-5 branch, Radix Bupleuri 3-5 branch, Herba speranskiae tuberculatae 1-3 branch, Radix Ginseng 1-3 branch, Radix Angelicae Sinensis 1-3 branch, Radix Paeoniae Rubra 1-3 branch at Caulis Sargentodoxae 3-5 branch.
Preferably; The Chinese medicine that the scorching clean decoction of the Chinese medicine basin of this treatment chronic pelvic inflammatory disease is divided by following optimum weight is processed: Rhizoma Curcumae 5 minutes, Olibanum 5 minutes; Rhizoma Atractylodis 3 minutes, Radix Codonopsis 4 minutes, Flos Carthami 4 minutes, Cortex Cinnamomi 3 minutes, Rhizoma Cyperi 2 minutes, Caulis Sargentodoxae 4 minutes, lose slurry grass 4 minutes, the Radix Paeoniae Alba 4 minutes, Radix Bupleuri 4 minutes, Herba speranskiae tuberculatae 2 minutes, Radix Ginseng 2 minutes, Radix Angelicae Sinensis 2 minutes, Radix Paeoniae Rubra 2 minutes.
Get above Chinese medicine, be decocted in water for oral dose, every day potion.
Fang Zhongyong Rhizoma Curcumae, Flos Carthami, the diffusing silt pain relieving of Radix Paeoniae Rubra; Caulis Sargentodoxae, Herba speranskiae tuberculatae lose the careless heat-clearing and toxic substances removing damp eliminating of slurry; Radix Codonopsis, Radix Ginseng, Rhizoma Atractylodis spleen invigorating dehumidifying; Radix Angelicae Sinensis, Olibanum, Radix Paeoniae Alba nourshing blood and promoting blood circulation; Rhizoma Cyperi, Radix Bupleuri are dredged strongly fragrant regulating menstruation; Cooperate a small amount of Cortex Cinnamomi warming YANG hemostasis.
Beneficial effect of the present invention:
Clinical practice proves, this basin scorching clean decoction has embodied the effect of heat-clearing and toxic substances removing, damp eliminating silt, has clearly and is not just hindering, mend do not love evil wonderful.Therapeutic effect is good, and the treatment cost is low, is worth clinical application.
Clinical data
1, physical data
Case comes from August, 2009 to 2010 year outpatient service in the August patient of my gynecological of institute, totally 212 examples.Be divided into treatment group and matched group at random, wherein 108 examples are organized in treatment, matched group 104 examples, before two groups of ages, the course of disease, the treatment integration situation through statistical test (t one thin t) the equal not statistically significant of difference (P＞0.05), data tool equilibrium comparability.(seeing table 1)
Table 1 liang group physical data relatively
Annotate: ' t-teat under the heterogeneity of variance condition
2, diagnostic criteria
Related content and combination < obstetrics and gynecology>related content according in < tcm clinical practice disease diagnosis criterion of therapeutical effect>are worked out: (1) part patient has the acute pelvic inflammatory disease medical history; (2) weigh down to expand pain or lumbosacral region of lower abdomen ached, after the fatigue of being everlasting, the sexual intercourse and menstrual phase increase the weight of, can be tired, menoxenia, leucorrhoea grow in quantity with low grade fever; (3) gynecologial examination: the uterus often is the position, back, and limitation of activity or adhesion are fixed, and tenderness is arranged.If endometritis, the uterus increases, tenderness; If salpingitis then contacts streak thing and mild tenderness is arranged in the one or both sides, uterus; If pelvic cavity knot is formed group 38 and knitted inflammation, the one or both sides, uterus have that lamellar thickens, tenderness.Or touch enclosed mass in the pelvic cavity one or both sides.(4) inflammatory masses of pelvic cavity or hydrops are found in ultrasound diagnosis.
3, Therapeutic Method
The scorching clean decoction of treatment group Chinese medicine basin of the present invention for oral administration, 1 dose of every day, decocting twice, extracting juice 200ml, clothes at twice.7 was 1 course of treatment, only used the I course of treatment in every month, and menstrual phase is stopped using, and the clean 2-3d of next menstruation begins the following course of treatment, observe the curative effect after 3 courses of treatment.
Quiet ampicillin 3g of matched group and 0.4% tinidazole 100ml, every day 2 times.7 was 1 course of treatment, only used for 1 course of treatment January, began following 1 course of treatment observe the curative effect after 3 courses of treatment during each afterwards menstrual onset.Two groups of cases were all followed up a case by regular visits to 1 year.
4, the standards of grading of local sign and symptom
With reference in " tcm clinical practice disease diagnosis criterion of therapeutical effect: " new drug Chinese medicine clinical research guideline " and related content work out.Uterine activity is limited, tenderness (5 minutes), and fallopian tube is streak tenderness (5 minutes), and uterus one side or bilateral lamellar thicken, tenderness (5 minutes); The tenesmus (3 minutes) of aching of lower abdomen waist, leukorrhagia increases (1 minute), low grade fever tired (1 minute); Abdominal pain in menstruation increases the weight of (1 minute), and the every increase of the course of disease added 0.5 fen in 1 year.
5, criterion of therapeutical effect
Work out with reference to " new drug Chinese medicine clinical research guideline " related content in " in the tcm clinical practice disease diagnosis criterion of therapeutical effect ".Cure: symptom, sign, inspection all recover normally, and scoring is 0 minute, and drug withdrawal does not have recurrence later six months; Produce effects: transference cure, gynecologial examination has clear improvement, and treatment back integration reduces below 2/3 than treatment is preceding; Take a turn for the better: symptom, sign and inspection all have and alleviate, and treatment back integration reduces below 1/3 before than treatment; Invalid: treatment back symptom does not have improvement.
6, therapeutic outcome
Before and after the treatment of two groups of cases local sign and symptom integral value relatively, local sign and symptom integral value all descend to some extent before and after two groups of cases treatments, show that two kinds of methods are to symptom, the sign of pelvic inflammatory disease all improve significantly (P＜0.01).(seeing table 2)
Local sign and the comparison of symptom integral value before and after the table 2 liang group case treatment (x ± s)
Two groups of case curative effects are relatively seen table 3
Table 3 liang back local sign of group case treatment and the comparison of symptom integral value (x ± s)
Table 4 liang group case cure rate is [example (%)] relatively
Annotate: X
2=42.45, ' P＜0.01
Table 3, table 4 result show that the treatment group is superior to matched group (P＜0.01) to symptom, the sign improvement of pelvic inflammatory disease; The treatment group is higher than matched group (P＜0.01) to the clinical cure rate of pelvic inflammatory disease.
Model case
Patient woman, 30 years old.Once gestation production 1 girl baby before 2 years, postpartum lochiorrhea, lasting month surplus side is clean.The every month obvious dysmenorrhea of having risen in back, pain unbearably.And leucorrhoea grow in quantity was once failed to respond to any medical treatment with wild flower bolt, antibiotic etc.Gynecologial examination: the bilateral adnexa has obvious tenderness, is diagnosed as pelvic inflammatory disease, obeys the scorching clean decoction of Chinese medicine basin of the present invention, and further consultation after 3 courses of treatment is stated dysmenorrhea and disappeared, and leucorrhea reduces, and gynecologial examination adnexa tenderness disappears.
The specific embodiment
Embodiment one:
Get Rhizoma Curcumae 50g, Olibanum 50g, Rhizoma Atractylodis 30g, Radix Codonopsis 40g, Flos Carthami 40g, Cortex Cinnamomi 30g, Rhizoma Cyperi 20g, lose slurry careless 40g, Radix Paeoniae Alba 40g, Radix Bupleuri 40g, Herba speranskiae tuberculatae 20g, Radix Ginseng 20g, Radix Angelicae Sinensis 20g, Radix Paeoniae Rubra 20g at Caulis Sargentodoxae 40g.Be decocted in water for oral dose by traditional method, every day potion.
Embodiment two:
Get Rhizoma Curcumae 30g, Olibanum 70g, Rhizoma Atractylodis 10g, Radix Codonopsis 30g, Flos Carthami 50g, Cortex Cinnamomi 10g, Rhizoma Cyperi 30g, lose slurry careless 50g, Radix Paeoniae Alba 50g, Radix Bupleuri 30g, Herba speranskiae tuberculatae 10g, Radix Ginseng 10g, Radix Angelicae Sinensis 30g, Radix Paeoniae Rubra 30g at Caulis Sargentodoxae 30g.Be decocted in water for oral dose by traditional method, every day potion.
Embodiment three:
Get Rhizoma Curcumae 70g, Olibanum 30g, Rhizoma Atractylodis 50g, Radix Codonopsis 50g, Flos Carthami 30g, Cortex Cinnamomi 50g, Rhizoma Cyperi 10g, lose slurry careless 30g, Radix Paeoniae Alba 30g, Radix Bupleuri 50g, Herba speranskiae tuberculatae 30g, Radix Ginseng 30g, Radix Angelicae Sinensis 10g, Radix Paeoniae Rubra 10g at Caulis Sargentodoxae 50g.Be decocted in water for oral dose by traditional method, every day potion.
Claims (2)
1. scorching clean decoction of the Chinese medicine basin of treating chronic pelvic inflammatory disease; The scorching clean decoction of Chinese medicine basin that it is characterized in that this treatment chronic pelvic inflammatory disease is processed by the Chinese medicine of following weight fraction: Rhizoma Curcumae 3-7 branch, Olibanum 3-7 branch; Rhizoma Atractylodis 1-5 branch, Radix Codonopsis 3-5 branch, Flos Carthami 3-5 branch, Cortex Cinnamomi 1-5 branch, Rhizoma Cyperi 1-3 branch, Caulis Sargentodoxae 3-5 branch, Herba Patriniae 3-5 branch, Radix Paeoniae Alba 3-5 branch, Radix Bupleuri 3-5 branch, Herba speranskiae tuberculatae 1-3 branch, Radix Ginseng 1-3 branch, Radix Angelicae Sinensis 1-3 branch, Radix Paeoniae Rubra 1-3 branch.
2. a kind of scorching clean decoction of Chinese medicine basin of treating chronic pelvic inflammatory disease according to claim 1; The scorching clean decoction of Chinese medicine basin that it is characterized in that this treatment chronic pelvic inflammatory disease is processed by the Chinese medicine of following optimum weight branch: Rhizoma Curcumae 5 minutes, Olibanum 5 minutes; Rhizoma Atractylodis 3 minutes, Radix Codonopsis 4 minutes, Flos Carthami 4 minutes, Cortex Cinnamomi 3 minutes, Rhizoma Cyperi 2 minutes, Caulis Sargentodoxae 4 minutes, Herba Patriniae 4 minutes, the Radix Paeoniae Alba 4 minutes, Radix Bupleuri 4 minutes, Herba speranskiae tuberculatae 2 minutes, Radix Ginseng 2 minutes, Radix Angelicae Sinensis 2 minutes, Radix Paeoniae Rubra 2 minutes.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102302746B (en) * | 2011-09-20 | 2014-01-29 | 浙江大学 | Traditional Chinese medicine composition for treating pelvic inflammatory disease (PID) and application thereof |
| CN105497636A (en) * | 2016-01-05 | 2016-04-20 | 邱钱勇 | Traditional Chinese medicine composition for treating chronic pelvic inflammation and preparation method and application thereof |
| CN106176939A (en) * | 2016-08-05 | 2016-12-07 | 逄素燕 | A kind of Chinese medicine preparation treating chronic pelvic inflammatory disease |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1319414A (en) * | 2001-01-19 | 2001-10-31 | 刘军 | Medicine for treating hecrosis of femoral head |
| CN101095751A (en) * | 2006-12-15 | 2008-01-02 | 甘肃奇正藏药有限公司 | Medicinal composition having functions of removing chloasma and improving nutritional anemia and method for preparing the same |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1319414A (en) * | 2001-01-19 | 2001-10-31 | 刘军 | Medicine for treating hecrosis of femoral head |
| CN101095751A (en) * | 2006-12-15 | 2008-01-02 | 甘肃奇正藏药有限公司 | Medicinal composition having functions of removing chloasma and improving nutritional anemia and method for preparing the same |
Non-Patent Citations (3)
| Title |
|---|
| 杨冷梅.慢性盆腔炎的中医药治疗近况.《安徽中医学院学报》.2005,第24卷(第2期),53-55. * |
| 率腊梅.近5 年中医治疗慢性盆腔炎研究概况.《甘肃中医》.2007,第20卷(第1期),34-37. * |
| 鲍连凤，等.中医药治疗慢性盆腔炎研究进展.《山东中医杂志》.2006,第25卷(第11期),788-791. * |
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