CN101972306B - Chinese medicinal capsule for treating chronic pelvic inflammatory disease - Google Patents

Chinese medicinal capsule for treating chronic pelvic inflammatory disease Download PDF

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CN101972306B
CN101972306B CN2010105167883A CN201010516788A CN101972306B CN 101972306 B CN101972306 B CN 101972306B CN 2010105167883 A CN2010105167883 A CN 2010105167883A CN 201010516788 A CN201010516788 A CN 201010516788A CN 101972306 B CN101972306 B CN 101972306B
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inflammatory disease
pelvic inflammatory
chinese medicinal
chronic pelvic
radix
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CN101972306A (en
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郁宝玲
张汉卿
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Abstract

The invention discloses a Chinese medicinal capsule for treating chronic pelvic inflammatory disease, which aims at the etiology caused by the chronic pelvic inflammatory disease, namely deficiency of vital energy, blood stasis, damp-heat brewing internally, interconnected damp-heat and blood stasis, and symptomatic blocks consorted for a long time. The Chinese medicinal capsule is prepared by refining the following natural Chinese herbal medicines by scientific compatibility: cinnamon, clematis root, red paeony root, tree peony bark, sinkiang arnebia root, suberect spatholobus stem and ovientvine. The capsule has the effects of clearing heat and promoting diuresis, tonifying vital energy and activating blood, and dissolving stasis, dissipating stagnation and dispersing swelling, has stable medicinal properties, improves the immunity of patients, promotes hyperplastic pelvic cavity tissue adhesion to recess and the masses to shrink, and also has the effects of treating both principal and secondary aspects of diseases, strengthening body resistance without stagnating evil, and eliminating evil without hurting body resistance. The clinical trial shows that the Chinese medicinal capsule has over 90 percent of effective rate on the chronic pelvic inflammatory disease, does not cause relapse of the disease, has low cost and is worth clinically popularizing and applying.

Description

A kind of Chinese medicinal capsule for the treatment of chronic pelvic inflammatory disease
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicinal capsule for the treatment of chronic pelvic inflammatory disease.
Background technology
Pelvic inflammatory disease is meant female internal genital organs and the inflammation that takes place of connective tissue, pelvic peritoneum on every side thereof, clinically is divided into acute, chronic two kinds, sees with chronic pelvic inflammatory disease more.Chronic pelvic inflammatory disease has the advantages that the course of disease is long, cure rate is low, relapse rate is high, can cause infertile, ectopic pregnancy, chronic pelvic pain, has a strong impact on women's physical and mental health.At present, doctor trained in Western medicine still do not have ideal Therapeutic Method, all exists therapeutic effect poor, the problem that relapse rate is high.
Summary of the invention
The purpose of this invention is to provide a kind of chronic pelvic inflammatory disease instant effect, Chinese medicinal capsule that therapeutic effect is good for the treatment of, is that the inventor inherits secret prescription handed down in the family from generation to generation, perfect through clinical practice for many years, the cause of disease that forms at primary disease is a blood stagnancy due to deficiency of QI, retention of damp-heat in the interior, damp and hot and congestion is tied mutually, with the passing of time consor disease piece.
Select natural Chinese medicinal herb, form through the science compatibility is refining.
The objective of the invention is to be achieved through the following technical solutions, the Chinese medicinal capsule of this treatment chronic pelvic inflammatory disease is made up of the Chinese medicine of following weight fraction: Cortex Cinnamomi 8-15 branch, Radix Clematidis 8-15 branch, Radix Paeoniae Rubra 8-15 branch, Cortex Moutan 5-10 branch, Radix Arnebiae (Radix Lithospermi) 5-10 branch, Caulis Spatholobi 5-10 branch, Caulis Sinomenii 5-10 branch.
The Chinese medicine that the Chinese medicinal capsule of this treatment chronic pelvic inflammatory disease is divided by following optimum weight is formed: Cortex Cinnamomi 12 minutes, Radix Clematidis 12 minutes, Radix Paeoniae Rubra 12 minutes, Cortex Moutan 7 minutes, Radix Arnebiae (Radix Lithospermi) 7 minutes, Caulis Spatholobi 7 minutes, Caulis Sinomenii 7 minutes.
Its preparation method is: with above crude drug, concoct according to a conventional method, be ground into powder, cross 200 mesh sieves, it is even to take by weighing powder mixes then in proportion, incapsulates to get final product.
Be monarch drug promoting the flow of QI-blood by warming the meridian and clots absorbing intestinal stasis relieving, be aided with Radix Paeoniae Rubra, Cortex Moutan, Radix Arnebiae (Radix Lithospermi) blood circulation promoting and blood stasis dispelling, clearing away heat and cooling blood with interior osmanthus, Radix Clematidis in the side, assistant is with Caulis Spatholobi, Caulis Sinomenii expelling wind and removing dampness, eliminating stasis to stop pain, spleen invigorating eliminate indigestion, inducing diuresis to remove edema, to help the power of repercussive.All medicines share, and play the effect of blood circulation promoting and blood stasis dispelling, slow elininating inflammation altogether.
Beneficial effect of the present invention: capsule of the present invention has clearing away heat-damp and promoting diuresis, benefiting QI for activating blood circulation, change silt mass dissipating and swelling eliminating, the property of medicine is steady, both improved patient's resistance, can impel outgrowth pelvic tissue adhesion to disappear again, enclosed mass dwindles, and plays treating both the principal and secondary aspects of a disease, sets upright evil, the eliminating evil positive effect of not hindering that do not stagnate.Through clinic trial, the effective percentage of chronic pelvic inflammatory disease is reached more than 90%, there is not recurrence, cost is low, is worth clinical application.
Clinical data
1, physical data
Select undergoing chronic pelvic inflammation 160 examples of year March in March, 2006 to 2007 in undergraduate course outpatient service prescription on individual diagnosis.Be divided into two groups at random, 90 examples are organized in treatment, age 25-56 (32 ± 6.31) year; Matched group 70 examples, age 25-54 (33 ± 5.28) year.Two groups at equal no difference of science of statistics in aspect such as sex ratio, age structure, the course of disease, inducement, clinical manifestation, x line rabat, Color Sonography inspections.
2, diagnostic criteria
Have that hypogastric region weigh down to expand, pain and lumbosacral region ache leucorrhoea grow in quantity; The patient who has has menoxenia or infertile history; Retroposition of uterus is seen in gynecologial examination, and is movable poor, and tenderness is arranged, and a side or bilateral adnexa have thickened tenderness or have been streak and increased slightly, or enclosed mass, tenderness are arranged; Get rid of pelvic malignant and endometriosis through B ultrasonic and lab testing.
3, Therapeutic Method
Two groups all give conventional therapy, and quiet notes ofloxacin injection 0.2g 1 time/d, treats 10d continuously.The treatment group is given capsule of the present invention on the conventional therapy basis, and 3 times/d, each 3 of zero capsule, one after each meal, withdraw menstrual period, and 10d was 1 course of treatment; Matched group on the conventional therapy basis oral dexamethasone tablet o.75mg, 3 times/d, 10d was 1 course of treatment.All patients followed up a case by regular visits to 3-4 month.In the 1st healing person's course of treatment after treatment in 2nd month, further consultation in 1 month after the drug withdrawal is treated continuously and was carried out curative effect in 3 months relatively.Observe two groups of clinical symptoms and sign, the inspections such as promoting the circulation of blood rheology, blood, urine, stool routine examination and liver, renal function of going forward side by side.Adopt SPSS 12.5 statistical softwares, measurement data is checked with t check or tI, enumeration data usefulness, check or correction, check.
4, curative effect judging standard
1. cure: subjective symptoms disappears, and leucorrhea is checked normal, and the bimanual examination body of uterus does not have tenderness, and attachment area does not have obviously and thickens, increases thick and tenderness, and ultrasonic demonstration pelvic hydrops disappears, and pelvic lump disappears, and uterine cavity does not have adhesion; 2. produce effects: subjective symptoms disappears, and leucorrhea is checked normal, and the bimanual examination body of uterus does not have tenderness, and attachment area thickens slightly, no tenderness, and ultrasonic demonstration hydrops disappears or on a small quantity, enclosed mass dwindles more than 2/3; 3. effective: subjective symptoms disappears, and leucorrhea is checked normal, the light tenderness of bimanual examination body of uterus, and attachment area thickens slightly, and mild tenderness is arranged, and ultrasonic demonstration hydrops disappears or is a small amount of, and enclosed mass dwindles below 2/3; 4. invalid: with the treatment before compare no change.
5, therapeutic outcome
Through clinic trial, the effective percentage of treatment group is apparently higher than matched group, and two groups of total effective rates relatively have significant difference (P<0.01), see the following form 1; And all significantly reduce (P all<0.01) after reaching treatment of control group before treating more on the same group after the treatment of blood index treatment group, see the following form 2.
Table 1 liang group therapeutic effect synopsis
Figure BSA00000314964100041
Table 2 blood index relatively
6, Chinese materia medica tocixity detects
Blood, urine, stool routine examination and liver, renal function there is no unusually before and after the treatment, untoward reaction also do not occur.
The specific embodiment
Embodiment one: Cortex Cinnamomi, Radix Clematidis, Radix Paeoniae Rubra, Cortex Moutan, Radix Arnebiae (Radix Lithospermi), Caulis Spatholobi, Caulis Sinomenii are concocted respectively according to a conventional method, be ground into powder, cross 200 mesh sieves, take by weighing Cortex Cinnamomi 120g, Radix Clematidis 120g, Radix Paeoniae Rubra 120g, Cortex Moutan 70g, Radix Arnebiae (Radix Lithospermi) 70g, Caulis Spatholobi 70g then, Caulis Sinomenii 70g powder mixes is even, incapsulate to get final product.
Embodiment two: Cortex Cinnamomi, Radix Clematidis, Radix Paeoniae Rubra, Cortex Moutan, Radix Arnebiae (Radix Lithospermi), Caulis Spatholobi, Caulis Sinomenii are concocted respectively according to a conventional method, be ground into powder, cross 200 mesh sieves, take by weighing Cortex Cinnamomi 80g, Radix Clematidis 150g, Radix Paeoniae Rubra 150g, Cortex Moutan 50g, Radix Arnebiae (Radix Lithospermi) 100g, Caulis Spatholobi 50g then, Caulis Sinomenii 100g powder mixes is even, incapsulate to get final product.
Embodiment three: Cortex Cinnamomi, Radix Clematidis, Radix Paeoniae Rubra, Cortex Moutan, Radix Arnebiae (Radix Lithospermi), Caulis Spatholobi, Caulis Sinomenii are concocted respectively according to a conventional method, be ground into powder, cross 200 mesh sieves, take by weighing Cortex Cinnamomi 150g, Radix Clematidis 80g, Radix Paeoniae Rubra 80g, Cortex Moutan 100g, Radix Arnebiae (Radix Lithospermi) 50g, Caulis Spatholobi 100g then, Caulis Sinomenii 50g powder mixes is even, incapsulate to get final product.

Claims (2)

1. a Chinese medicinal capsule for the treatment of chronic pelvic inflammatory disease is characterized in that the Chinese medicinal capsule of this treatment chronic pelvic inflammatory disease is made up of following parts by weight of Chinese traditional medicine: Cortex Cinnamomi 8-15 part, Radix Clematidis 8-15 part, Radix Paeoniae Rubra 8-15 part, Cortex Moutan 5-10 part, Radix Arnebiae (Radix Lithospermi) 5-10 part, Caulis Spatholobi 5-10 part, Caulis Sinomenii 5-10 part.
2. a kind of Chinese medicinal capsule for the treatment of chronic pelvic inflammatory disease according to claim 1 is characterized in that the Chinese medicinal capsule of this treatment chronic pelvic inflammatory disease is made up of the Chinese medicine of following optimum weight part: 12 parts of Cortex Cinnamomis, 12 parts of Radix Clematidis, 12 parts of Radix Paeoniae Rubra, 7 parts of Cortex Moutans, 7 parts of Radix Arnebiae (Radix Lithospermi)s, 7 parts of Caulis Spatholobis, 7 parts of Caulis Sinomeniis.
CN2010105167883A 2010-10-09 2010-10-09 Chinese medicinal capsule for treating chronic pelvic inflammatory disease Expired - Fee Related CN101972306B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103585412B (en) * 2013-10-30 2015-05-27 武汉科斯瑞科技有限公司 Chinese herbal preparation for treating pelvic inflammation and uterine fibroid

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1191733A (en) * 1997-02-24 1998-09-02 山东医科大学附属医院 Externally used medicine bag for curing chronic pelvic infection, endometriosis, chronic cervicitis and menalgia and its making process
CN101066410A (en) * 2007-06-01 2007-11-07 刘桂兰 Chinese medicine prepn for treating women's chronic pelvic inflammation and its prepn process
CN101601832A (en) * 2008-06-12 2009-12-16 张晓芳 A kind of medicine for the treatment of chronic pelvic inflammatory disease and preparation method thereof
CN101780160A (en) * 2010-04-07 2010-07-21 史长山 Traditional Chinese medicine preparation for treating gynecological disease and preparation method thereof
CN101829247A (en) * 2010-05-20 2010-09-15 南京中医药大学 Chinese medicinal compound effective component for treating gynecological diseases and preparation method and application thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1191733A (en) * 1997-02-24 1998-09-02 山东医科大学附属医院 Externally used medicine bag for curing chronic pelvic infection, endometriosis, chronic cervicitis and menalgia and its making process
CN101066410A (en) * 2007-06-01 2007-11-07 刘桂兰 Chinese medicine prepn for treating women's chronic pelvic inflammation and its prepn process
CN101601832A (en) * 2008-06-12 2009-12-16 张晓芳 A kind of medicine for the treatment of chronic pelvic inflammatory disease and preparation method thereof
CN101780160A (en) * 2010-04-07 2010-07-21 史长山 Traditional Chinese medicine preparation for treating gynecological disease and preparation method thereof
CN101829247A (en) * 2010-05-20 2010-09-15 南京中医药大学 Chinese medicinal compound effective component for treating gynecological diseases and preparation method and application thereof

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