CN102132884A - Preparation method of foods, beverages and medicines containing apocynum venetum extract - Google Patents
Preparation method of foods, beverages and medicines containing apocynum venetum extract Download PDFInfo
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- CN102132884A CN102132884A CN2011100807623A CN201110080762A CN102132884A CN 102132884 A CN102132884 A CN 102132884A CN 2011100807623 A CN2011100807623 A CN 2011100807623A CN 201110080762 A CN201110080762 A CN 201110080762A CN 102132884 A CN102132884 A CN 102132884A
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Abstract
The invention belongs to preparation of foods, beverages and medicines containing apocynum venetum and relates a preparation method of foods, beverages and medicines containing apocynum venetum. 0.5-100% of apocynum venetum extract is added into foods, beverages and medicines to prepare various solid, liquid, beverages, tablets and capsules and the like which have the functions of relieving, improving and treating symptoms of addictive dependence on plant and chemically-synthesized products such as tobacco, marijuana and opium and the like. In the invention, the resource of the apocynum venetum has wide resource and wide application scope.
Description
Technical field
The present invention relates to contain the preparation method of food, beverage and the medicine of bluish dogbane.More definite says, the food that contains apocynum extract, beverage and the medicinal mixture of the present invention preparation have and alleviate and improve the effect of treatment because of the habituation dependence symptom of sucking plant class such as tobacco hemp opium and chemical synthesis category.
The extract that the present invention relates to use the Chinese herb bluish dogbane prepares food, beverage and medicinal mixture as the additive of food, beverage and medicine.The main effect that contains food, beverage and the medicinal mixture of apocynum extract is that Xu has outside normal edible, the medicinal efficacy of food, beverage and medicine, and main is that this mixture has alleviations especially, improves the effect for the treatment of because of the habituation dependence symptom of sucking plant class such as tobacco hemp opium and chemical synthesis category.
Background technology
Produce the harm of dependence owing to suck plant class such as tobacco hemp opium and chemical synthesis category to human body, few to this disease research in the world at present, do not meet any successful report as yet.
The food that contains apocynum extract, beverage and the medicine that the objective of the invention is to use the inventive method preparation is adapted to suck the habituation dependence symptom of plant class such as tobacco hemp opium and chemical synthesis category especially.Often use series of products and the medicine that contains apocynum extract of the present invention, can alleviate, improve until curing above-mentioned symptom for above-mentioned habituation dependent.
Summary of the invention
The series of products that contain apocynum extract promptly contain food, beverage and the medicine of apocynum extract, it is characterized in that wherein containing the apocynum extract of 0.5-100%.It is that 0.5-50% is in food, beverage weight that food and beverage contain apocynum extract.It is 50-100% that medicine contains apocynum extract
Apocynum extract can be a dry, also can be the aqueous solution.0.5-50% is in food and beverage weight at least to contain its apocynum extract content of food, beverage and medicine of apocynum extract, and content of drug is 50-100%.
Specifically when preparation contained the food of apocynum extract and beverage, its apocynum extract content approximately was the 0.5-50% of food and beverage.When preparation contained the medicine of apocynum extract, its apocynum extract content was that 50-100% is good.
Usually apocynum extract is to extract with polar solvent.For example: water or ethanol extract from bluish dogbane or Folium Apocyni Veneti, and subsequently that extract is concentrated, drying is made apocynum extract.It is nontoxic to measure the confirmation apocynum extract through the drug testing institution, wherein contains the Quercetin of 0.1-1.5%, in the weight of apocynum extract.
Apocynum extract is to extract with water with polar solvent in the practicality, because water is pollution-free, has no side effect in residual and food, the beverage mix, and need not reclaim.Medicine extracts the best with ethanol, and ethanol can recycling.
The method for preparing apocynum extract with aqueous solvent is: place one to have in the firing equipment of stirring clean bluish dogbane or Folium Apocyni Veneti, add 10-20 water doubly, heat with indirect jacket type heater, or directly spray into steam, boiling 0.5-4 hour, overanxious then, decompression distillation, temperature is not higher than 80 ℃, and under vacuum, temperature is not higher than about 1 hour of 80 ℃ of dryings at last.Generally can get the extract of Folium Apocyni Veneti amount 1/10.The apocynum extract that is equipped with gained through last legal system has following feature:
Color: brown
Taste: little puckery
Quercetin content: 0.1-1.5%
The scapus of also available in addition direct squeezing bluish dogbane is squeezed the juice its pulpous state to be dissolved in the 10-20 times of water and makes the bluish dogbane water-soluble extractive, generally can obtain the extract of its scapus amount 1/10-1/15.This extract is a white, and further feature is identical with the bluish dogbane of method for preparing.
Solubility test: dry apocynum extract mixes by 1:20 with water, should all dissolve at 80 ℃, and precipitation must not be arranged.
Use polar solvent, particularly mix with food, beverage and medicine as follows with the form of the dry or the aqueous solution as the apocynum extract that solvent makes, be used to make food, beverage and medicine with water, ethanol.
With apocynum extract and other food additives, as food additives (natrium citricum, D-sorbite, cornstarch and fruit essence etc.), or flavor enhancement (cyclodextrin, nutmeg), sweetener (white granulated sugar, honey, grape wine etc.), medical additive (Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae, the fruit of Chinese magnoliavine, almond, Momordica grosvenori, the maple bucket, glossy ganoderma, and American Ginseng etc.) mix, add 10-20 water doubly, normal temperature or be heated to 25-40 ℃ or in digesting apparatus, boil under mix, said mixture is cooled to room temperature, and through 20-60/ cun screen filtration, be added under the normal temperature or be heated to 25-40 ℃ the food that is liquid condition that is preparing, beverage, in the medicine, carefully mix, make relative manufactured goods subsequently according to a conventional method.For Food ﹠ Drink, the extractive content at least 0.5% of bluish dogbane is generally 0.5-50%, and for medicine, the content of apocynum extract is at least 50-100%, in final mixture weight, decides according to made type of goods.
The food clearing sugar lozenge that contains 8% apocynum extract for the preceding method preparation, through because of the habituation crowd of cigarette more than 10 years that enfleurage eats, used 30 days with normal amount, can obviously reduce craving for tobacco, reduce smoking capacity, make that carbonomonoxide concentration descends in the body, efficiently reach 99%.
Above efficacy determination is through " Nutrition and Food Safety Office of China Disease Prevention and control Centre " development test report, " Chinese Tobacco Control association assert "
The World Health Organization is expounded through peer review: the habituation=heroin of nicotine
Nicotine in the tobacco (nicotine) just can produce the habituation dependence.
Example 1: with containing apocynum extract white mouse is carried out acute detoxifcation test, confirm after smearing apocynum extract, to bring back to life again, thereby the proof apocynum extract can be alleviated the effect of tobacco nicotinism state rapidly because of being coated with the seemingly-dead white mouse of nicotine.
: example 2: white mouse is controlled the excitability test with containing apocynum extract, drip the white mouse that contains heroin Xishui liquid simultaneously for two groups with A/B, its excitement levels progressively strengthened in 5-10 minute, the A group is not stopped continuously to run and was stopped in 2-3 hour, alleviation was run after B group white mouse was dripped suction with the apocynum extract Xishui, only run stopped in 20-40 minute, thereby the confirmation apocynum extract can be controlled alleviation heroin excitatory state rapidly.
Example 3: white mouse is controlled the excitability test with apocynum extract, drip the white mouse that suction contains synthetic methamphetamine Xishui simultaneously with two groups of A/B, its excitement in 5-10 minute progressively strengthens, the A group is not stopped continuously to run and was stopped in 1:30-2:30 minute, alleviation was run after B group white mouse was dripped suction with the apocynum extract Xishui, only run stopped in 15-40 minute, thereby the confirmation apocynum extract can be controlled the excitatory state of alleviating the synthetic methamphetamine rapidly.
Experiment showed, the Quercetin that is contained in the apocynum extract, calculating its content with flavonoids is 0.1-1.5%, has control and alleviates the nicotine toxin poisoning, also plays control and alleviates heroin, the effect of methamphetamine excitatory state.
The invention has the advantages that the bluish dogbane wild resource is wide, bluish dogbane is extracted convenient and simple, cost is low, and when preparation contained the food, beverage of apocynum extract and medicine, bluish dogbane very easily was in harmonious proportion with employed food additives, sweetener, flavor enhancement and Chinese herbal medicine class and mixes.By PROCESS FOR TREATMENT, the fine maintenance of special health care of apocynum extract, and make mouthfeel and the taste that has improved, to the production of medicine and use safer convenience, this also is another advantage of invention.
The present invention further describes in detail and is illustrated by following enforcement, but embodiment is not limited to scope of the present invention.
Embodiment 1
The preparation of bluish dogbane water extract
Bluish dogbane places one to have in the reactor of agitating device for 100 kilograms, adds 1000 kilograms of entry, and heating was stirred 2 hours under slight boiling condition.The cooling final vacuum filters, and gets 830 kilograms of filtrates.Concentrate 80 ℃ of decompressions, get 18 kilograms of concentrates.80 ℃ of dryings are 1 hour under vacuum condition, obtain 10 kilograms of dry apocynum extracts.
Feature is as follows:
Color; Brown
Taste; Little puckery
Quercetin content: 0.98%(is in flavonoids)
Solubility test: dry apocynum extract mixes with hot water 1:20,80 ℃ of all dissolvings.
Embodiment 2
Stem of Folium Apocyni Veneti is cleaned for 1 kilogram, chopping extrudes white pulpous state juice with squeezer, and above-mentioned slurries are dissolved in 20 times of water, shallow white bluish dogbane extract can be become with 20-60 order/cun screen filtration insoluble matter, about 50 grams of bluish dogbane can be obtained after the vacuum drying.
Above-mentioned apocynum extract contains Quercetin 0.98%(flavonoids meter)
Embodiment 3
In edible beverage carambola juice process, 2 kilograms of the apocynum extracts that contains decolouring, add in the digester, be heated to 25-40 ℃, fully stir with 20 kilograms in carambola juice, 10 kilograms of granulated sugar, 0.1 kilogram in essence, 1.0 kilograms of stabilizing agents, 0.5 kilogram of cyclodextrin, 0.5 kilogram of Bulbus Fritillariae Cirrhosae, 34 kilograms of mixing materials of water, mixed processing makes 100 kilograms of carambola beverages, wherein add apocynum extract and account for 5%.The can after cooling, sterilization of above-mentioned beverage is manufactured goods.With other the edible beverages that can make apocynum extract with quadrat method, as fruit type beverage or other edible health beverages such as pear beverages.This beverage can reduce craving for tobacco, Qingxu cigarette poison, often drinks, and oral peculiar smell, expectoration that the smoker is caused because of smoking are breathed heavily symptom and had clear improvement.Can alleviate, improve habituation dependence symptom especially because of plant classes such as the opium that smokes cannabis and chemical synthesis category.
It is example 4
In preparation autumn pear cough-relieving stream cream drug process, 5 kilograms of the autumn pears of extracting juice will be pressed, 3 kilograms of white granulated sugars, honey 200 grams, low baking temperature boiling in sugar dissolving kettle, the thick shape of simmer down to, apocynum extract 400 grams and cyclodextrin, Poria cocos, each 50 gram of Bulbus Fritillariae Cirrhosae are put into 10 times of clear water, and little fiery infusion becomes the soup shape behind the first very hot oven in special copper pot, joins in the dense magma of autumn pear after filtering.Heat be condensed into paste to 25-40 ℃ of low baking temperature after cooling naturally, finished product is made in the sterilization of envelope bottle.Wherein, the apocynum extract effective ingredient accounts for 10% of finished product cough-relieving stream cream.This autumn pear cough-relieving stream cream because of containing the apocynum extract composition, can reduce craving for tobacco, Qingxu cigarette poison except that normal cough-relieving curative effect, be applicable to because of smoking chronic bronchitis patient such as cause that expectoration is breathed heavily.Other cough-relievings that contain apocynum extract be can also make in this way and cream such as hairyvein agrimony CHUANBEI PIPA GAO etc. flowed.Especially effectively alleviate, improve because of smoke cannabis, the habituation dependence symptom of plant class such as opium and chemical synthesis category.
Embodiment 5
In the toothpaste preparation process, under the normal temperature with 1 part of aluminium-magnesium silicate and 0.25 part of mixing of carboxymethyl cellulose, under maximum shear, stir and pour in the water, until stirring, will again 5.5 parts of apocynum extracts, 1 part of cyclodextrin, 0.15 part of citric acid, peppermint oil 3 be added dropwise to and mix after (70%) 12 part of sorbierite, 12 parts of glycerine, 50 parts of Tri-Compress and above-mentioned the mixing subsequently.Sterilization according to a conventional method at last is in the plastics extruding pipe of packing into.This toothpaste that contains apocynum extract has special counteract oral malodour, removes effects such as tobacco tar stain the smoker.
Embodiment 6
Suck and in boiling Ao sugar pot, add white granulated sugar 500 grams in the lemon sugar preparation process earlier, 50 milliliters in clear water, very hot oven boils to be endured, in 25-50 ℃ of sugar juice, add 3 of happy sugared 75 grams, citric acid 0.5 gram, peppermint oil then, mix, when occurring turning over bubble, be cooled to 20-30 ℃, subsequently apocynum extract (wherein containing apocynum extract 25 gram, sweetener cyclodextrin 10 grams) is joined in the digester, continuing to stir is the malt sugar shape.The malt sugar that will add the bluish dogbane working substance at last pours on special stainless steel processing plate, scribbles one deck peanut oil on this plate.Malt sugar is made candy batch on flat board, be shaped into sugar after the cooling.This lemon sugar contains apocynum extract 5.5%(in mixture weight).This bluish dogbane lemon sugar is salubrious crisp fragrant and sweet, can reduce craving for tobacco, Qingxu cigarette poison, and is often edible, also especially to causing that because of smoking the productive cough patient with sympotoms has clearing phlegm and relieving cough, removes effects such as oral peculiar smell.Effectively alleviate, improve the habituation dependence symptom of plant class such as the opium that smokes cannabis and chemical synthesis category.
Can also make bluish dogbane peppermint sugar and bluish dogbane pineapple sugar etc. with said method.
Embodiment 7
In the preparation process of chewing gum, APME 20%, sorb glycolipid 20%, cornstarch 20%, cured 36% heating of rice bran are dissolved, add apocynum extract 5%, sweetener cyclodextrin 1% subsequently at 25-40 ℃, dissolving is cooled to room temperature after mixing, add lemon extract 0.5%, splash into 3 of peppermint oils, evenly mixing aftershaping again is tablet gum, or mixture is dried to particle below 12 orders with spray method, become the spherical particles chewing gum that contains bluish dogbane.Also can in the mixture preparation process, add the foaming thing, become the foaming chewing gum that contains bluish dogbane.The above-mentioned effective chewing gum of bluish dogbane that contains has and can reduce craving for tobacco, Qingxu cigarette poison among the embodiment 4, improves the effect that symptom and pharyngitis symptom are breathed heavily in the oral peculiar smell, the expectoration that cause because of smoking.Effectively alleviate, improve because of plant class and chemical synthesis category habituation dependence symptoms such as the opium that smokes cannabis.
Embodiment 8
In preparation tealeaves (jasmine tea, black tea, oolong tea) process, the aqueous solution of apocynum extract 3.5%, the tuber of dwarf lilyturf 1%, sweetener nutmeg 0.5% is evenly sprayed into the tealeaves surface that (with steam or compressed air) preparing, leave standstill after 0.5-4 hour and be dried into finished product, this tealeaves that contains apocynum extract, do not influence the fragrance and the taste of former tea, can reduce craving for tobacco, Qingxu cigarette poison, have oral peculiar smell, the expectoration that cause because of smoking are breathed heavily and the smoker of bronchitis symptom, often drink the effect of significantly slowing down above-mentioned symptom.
Embodiment 9
In preparation bluish dogbane solid particle is taken after mixing it with water the process of beverage, with 15 kilograms of 100 kilograms of granulated sugar, 0.65 kilogram of citric acid, 0.6 kilogram of natrium citricum, honey with 10-20 times of water in the sugar dissolving kettle of belt stirrer, heat 25-40 ℃ fully mix down till.Add 5 kilograms of apocynum extracts, 0.5 kilogram of fully mixing with it of cyclodextrin to said mixture; being heated to 60-75 ℃ subsequently wakes up with a start vacuum and concentrates; make the concentrate water content account for 10-15%; be cooled to room temperature; add 5 of lemon oils; left standstill 1-2 hour, further deliver to comminutor granulation 20-40 order/cun, and at 60-75 ℃ of vacuum drying 20-30 minute.The solid beverage that contains bluish dogbane contains apocynum extract 3.5%, and its final moisture is 4-6%, and the bluish dogbane solid particle beverage can directly be taken after mixing it with water.This beverage can reduce craving for tobacco, Qingxu cigarette poison, often takes, and oral peculiar smell, the expectoration symptom that is caused by smoking had clear improvement.More effective alleviation, improve because of plant class such as the opium that smokes cannabis and chemical synthesis category and get habituation dependence symptom.
Above-mentioned bluish dogbane solid particle repeats to add different fruit juices in the beverage preparation or fruit essence can prepare the different-style taste.
Embodiment 10
In the bluish dogbane solid instant tea beverage preparation process, tealeaves (jasmine tea, chrysanthemum tea, black tea, oolong tea etc.) water is washed away assorted back with 40-60 ℃ of poach half an hour, mention tea juice.Finished product syrup, apocynum extract, cyclodextrin are added, evenly stir with it, fully mix.Mixed liquor is heated to 50-60 ℃ subsequently, vacuum concentrates, and further carry out the granulation of 20-40 order, and vacuum drying is the yellow quartz body.Bluish dogbane solid instant tea beverage contains Herba Agrimoniae extract 3.5%.This beverage can reduce craving for tobacco, Qingxu cigarette poison, often drinks oral peculiar smell, expectoration symptom that the smoker is caused because of smoking and has clear improvement.Effectively alleviate, improve habituation dependence symptom to plant class such as the opium that smokes cannabis and chemical synthesis category.
Claims (6)
1.1: the food that contains apocynum extract, the preparation method of beverage and medicine, it is characterized in that: a: with apocynum extract and food additives, sweetener and medicinal additive mix, adding 10-20 water doubly fully stirs at normal temperature or 25-45 ℃ of degree of heating or under boiling in digesting apparatus, wherein be that food additives are selected natrium citricum, D-sorbite, cornstarch, sweetener is selected white granulated sugar, honey, glucose, flavor enhancement is selected from cyclodextrin, and medical additive is selected from Radix Glycyrrhizae, ginkgo leaf, Bulbus Fritillariae Cirrhosae, almond, Momordica grosvenori, the tuber of dwarf lilyturf, glossy ganoderma and American Ginseng.
2.b: said mixture cooled off room temperature and through 20-80 order/cun screen filtration.
3.c: above-mentioned filtered fluid is added to normal temperature or heated in the Foods or drinks that is liquid status that is preparing to 25-40 ℃ of degree, and carefully mix, make corresponding manufactured goods subsequently according to a conventional method.
4.d: wherein the content of apocynum extract is 0.5-50%, in the weight of Foods or drinks mixture.
5.e: the content of apocynum extract is that 50-100% can be made as medicine
2:, it is characterized in that apocynum extract wherein is that water extracts according to the claim 1 described preparation method who contains food, beverage and the medicine of apocynum extract.
6.3: according to the claim 1 described preparation method who contains food, beverage and the medicine of apocynum extract, it is characterized in that apocynum extract wherein comes out with alcohol extract.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102960412A (en) * | 2012-12-28 | 2013-03-13 | 李坤宇 | Milk flavoured fried dough twist and preparation method thereof |
| CN103655650A (en) * | 2012-09-12 | 2014-03-26 | 深圳市日月昌科技有限公司 | Chinese herb extract for treating drug addiction and resisting relapsing |
| CN104644730A (en) * | 2013-11-19 | 2015-05-27 | 深圳市日月昌科技有限公司 | Detoxification-used traditional Chinese medicine composition and preparation method thereof |
-
2011
- 2011-03-31 CN CN2011100807623A patent/CN102132884A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103655650A (en) * | 2012-09-12 | 2014-03-26 | 深圳市日月昌科技有限公司 | Chinese herb extract for treating drug addiction and resisting relapsing |
| CN102960412A (en) * | 2012-12-28 | 2013-03-13 | 李坤宇 | Milk flavoured fried dough twist and preparation method thereof |
| CN102960412B (en) * | 2012-12-28 | 2014-02-19 | 李坤宇 | Milk flavoured fried dough twist and preparation method thereof |
| CN104644730A (en) * | 2013-11-19 | 2015-05-27 | 深圳市日月昌科技有限公司 | Detoxification-used traditional Chinese medicine composition and preparation method thereof |
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Application publication date: 20110727 |