CN102113493A - Sterilization composite containing mepronil and tricyclazole - Google Patents
Sterilization composite containing mepronil and tricyclazole Download PDFInfo
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- CN102113493A CN102113493A CN2010100015719A CN201010001571A CN102113493A CN 102113493 A CN102113493 A CN 102113493A CN 2010100015719 A CN2010100015719 A CN 2010100015719A CN 201010001571 A CN201010001571 A CN 201010001571A CN 102113493 A CN102113493 A CN 102113493A
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- tricyclazole
- mebenil
- bactericidal composition
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Abstract
The invention discloses a sterilization composite containing mepronil and tricyclazole, and a preparation method and application thereof. The sterilization composite is characterized by containing the mepronil, the tricyclazole and other adjuvant, wherein the weight ratio of the mepronil to the tricyclazole is 2-80:1-50. The sterilization composite can be applied to prevent and cure sigatoka, rhizoctorzia solani, magnaporthe oryzae, erysiphe graminis, wheat rust, peanut leaf spot and other fungus disease. The composite is wide in application range, low in cost and good in effect. Reports about the blending of the mepronil and the tricyclazole do not exist at home and abroad, so that the invention is provided.
Description
Technical field
The invention belongs to the agriculture chemical compounding field, relate to a kind of bactericidal composition and uses thereof, especially a kind of is the bactericidal composition and the application thereof of main active with mebenil and tricyclazole.
Background technology
Using chemical agent is the most effectively means of control fungal diseases of plants.But long-term use single chemical bactericide continuously high dose, cause problems such as residual, the environmental pollution of medicament and anti-pesticide resistance fungi development easily.Reasonably chemical bactericide is composite or be mixed and have the expansion fungicidal spectrum, improve control efficiency, prolong the optimum period for applying fertilizer, reduce dosage, reduce poisoning, reduce residual, delay fungi drug resistance and positive characteristics such as drug-fast generation and development, bactericide compounded or to be mixed be one of the effective method the most that addresses the above problem.Exploitation new product bactericide price is constantly soaring, and by contrast, exploitation is efficient with research, low toxicity, low-residual composite be mixed have small investment, the lead time is short and be subjected to domestic and international attention, strengthens the development dynamics one after another.
Mebenil:
These product are bactericide, and Basidiomycetes is had control efficiency efficiently, especially to the rust of wheat, cereal, peanut, and potato rhizoctonosis, other root diseases that Wheat Root Rot Sclerotium rolfsii and rhizoctonia cause all have good control efficiency.Also can be used for preventing and treating cotton in seedling stage damping off, cotton red rot, peanut leaf blight, cercospora leaf spot of sugar beet, rice blast, banded sclerotial blight etc.After revolving medicine, these product have certain effect resistant to lodging to various crop.This kind protective effect is strong, but result of treatment is relatively poor, early stage dispenser, and sick Sheng phase pesticide supplying effect is relatively poor.
Tricyclazole:
The moderate toxicity bactericide, interior absorption is stronger, is mainly used in control rice fungus diseases evil, can be absorbed, and be transported to each one of rice strain by rice root, stem, leaf rapidly.Antiscour power is strong, and the spray medicine was met rain after one hour, also need not fill spray.Can stop germ to invade and reduce the generation of magnaporthe grisea spore effectively, thereby excellent protective is arranged, sprayed medicine before germ is contaminated, preventive effect the best also can be used for the rice shoot root and handles, and prevents and treats early stage leaf pest.Rice blast is had special efficacy, and control efficiency is better than bactericide such as kitazine, Isoprothiolane, Hinosan, and is general all more than 90%, 15～20 days lasting periods.Control seedling pest, leaf pest, every mu of usefulness 20% wetting powder 75g is to water 50kg spraying or to water 7～10kg atomizing; The control panicle blast should be in paddy rice booting stage (promptly earing preceding 3 days), and minority helps disease as weather and takes place at cut phase spray medicine, then needs after dispenser 10～14 days, carries out dispenser for the third time.If disease can increase a mu consumption when serious.
Sigatoka: be one of the most important disease of China's banana that causes harm, it is caused by multiple fungi, mainly contains Cercospora leaf spot, dark two mould leaf spots of spore and the mould leaf spot of little Dou Shi.Cercospora leaf spot comprises that macula lutea type leaf spot claims two kinds of sigatoka leaf spot disease and blackspot type leaf spots again.This disease lower blade that causes harm earlier, after progressively spread to upper blade, scab just is grain of rice shape or linear, faint yellow or brown, parallel with vein, see blade back earlier, after develop into ellipse or strip, yellowish-brown or pitchy, blade repeated infection, a large amount of scabs separately occur, scab converges for many years, causes that any of several broadleaf plants leaf large tracts of land is withered.Dark two mould leaf spot of spore claims grey line disease again, causes that oval taupe scab in blade face or leaf margin are withered.Scab initial stage brown, after expand to central authorities' light brown, tool wheel line, auburn elliptical spot on every side; Scab is invaded along the leaf margin water hole, water stain shape, crineous, crescent or oval, the scab that differs in size appear in the initial stage leaf margin, later stage is united brown, wave ring grain dead band for being parallel to arteries and veins in the leaf along leaf margin, the back becomes canescence, matter is crisp, and rainy season, lurid chlorisis band appearred in sick strong portion intersection.The mould leaf spot of little Dou Shi claims coal line disease again, common in, lower blade morbidity.Scab brown, ellipse, tangible wheel line is arranged, pilosity is born in leaf margin, and there is obvious limit in sick strong portion.Leaf spot causes that mainly banana blade large tracts of land is withered, influence leaf photosynthesis, causes plant early ageing, has a strong impact on that fruit is substantial, output and storage property, and the diseased plant fruit is very easily rotten.
Summary of the invention
The objective of the invention is at above-mentioned variety of issue,, thereby provide a kind of bactericidal composition of preventing and treating the various crop fungal disease for pesticide resistance, expansion fungicidal spectrum, enhancing drug effect, the reduction drug cost that overcomes and delay existing agricultural chemicals.
A further object of the invention provides the purposes of this bactericidal composition.
Measure of the present invention realizes by following measures.
A kind of bactericidal composition, it contains mebenil and tricyclazole, and wherein the weight ratio of mebenil and tricyclazole is 0.1～50: 0.1～60.
Described bactericidal composition, wherein the more excellent weight ratio of mebenil and tricyclazole is 5～50: 5～60.
Described bactericidal composition, wherein to accumulate the weight ratio of shared preparation be 10～83% to two kinds of active principles of mebenil and tricyclazole.
Described bactericidal composition, mebenil and tricyclazole and auxiliary agent, carrier etc. are processed into any one formulation that allows on the agricultural chemicals.
Described bactericidal composition is characterized in that the formulation that can be processed into is suspending agent, aqueous emulsion, microemulsion, wetting powder, water dispersible granules and microcapsule formulations etc.
Described bactericidal composition is used to prevent and treat multiple fungal diseases such as sigatoka, rice sheath blight disease, rice blast, wheat powdery mildew, wheat rust, leaf spot of peanut.
Microbicide compositions with synergistic effect takes following measure to realize:
One of technical scheme of the present invention, described bactericidal composition are suspending agent, and the percentage by weight of component is:
Mebenil 0.1～50%
Tricyclazole 0.1～60%
Dispersant 5～20%
Antifreezing agent 0.5～3%
Thickener 0.1～2%
Defoamer 0.1～0.8%
Water surplus
The concrete production stage of this bactericidal composition suspending agent is earlier other auxiliary agents to be mixed, mix through high speed shear, add mebenil and tricyclazole, abrading-ball is 2～3 hours in ball crusher, make a diameter all below 5mm, make the suspending agent preparation that contains the bactericidal composition of mebenil and tricyclazole of the present invention.
Two of technical scheme of the present invention, described bactericidal composition are aqueous emulsion, and the percentage by weight of component is:
Mebenil 0.1～50%
Tricyclazole 0.1～60%
Emulsifier 3～30%
Solvent 5～15%
Stabilizing agent 2～15%
Antifreezing agent 1～5%
Defoamer 0.1～8%
Thickener 0.2～2%
Water surplus
The concrete production stage of this bactericidal composition aqueous emulsion is: at first former medicine mebenil is added with tricyclazole, solvent and emulsifier, cosolvent and be in the same place, make and be dissolved into uniform oil phase; With part water, antifreeze, other insecticides adjuvant such as antimicrobial mixes into uniform water; When the reactor high speed stirs, oil phase is added water, slowly add water, open clipper and carry out high speed shear, and add remaining water, shear half an hour approximately, form the aqueous emulsion of oil-in-water type until reaching the phase inversion point.Promptly make the aqueous emulsion of the bactericidal composition that contains mebenil and tricyclazole.
Three of technical scheme of the present invention, described bactericidal composition are microemulsion, and the percentage by weight of component is:
Mebenil 0.1～50%
Tricyclazole 0.1～60%
Solvent 1～30%
Emulsifier 3～30%
Stabilizing agent 2～15%
Synergist 2～10%
Water 10～78%
The concrete procedure of processing of this bactericidal composition microemulsion is: mebenil and the former medicine of tricyclazole are added in the solvent, add auxiliary agents such as emulsifier, stabilizing agent and synergist while stirring, at last it is added in the entry and stir, form transparent and homogeneous liquid, promptly get the microemulsion of the present composition.
Four of technical scheme of the present invention, described bactericidal composition are wetting powder, and the percentage by weight of component is:
Mebenil 0.1～50%
Tricyclazole 0.1～60%
Dispersant 3～20%
Wetting agent 3～10%
Filler 10～70%
The concrete procedure of processing of this bactericidal composition wetting powder is: press above-mentioned prescription with mebenil and tricyclazole and dispersant, wetting agent and filler mixing, in stirred tank, evenly stir, behind airslide disintegrating mill, mixing, promptly can be made into the wetting powder of the present composition.
Five of technical scheme of the present invention, described bactericidal composition are water dispersible granules, and the percentage by weight of component is:
Mebenil 0.1～50%
Tricyclazole 0.1～60%
Dispersant 3～20%
Wetting agent 3～10%
Disintegrant 2～5%
Filler 10～70%
The concrete procedure of processing of this bactericidal composition water dispersible granules is: by above-mentioned prescription mebenil, tricyclazole and dispersant, wetting agent, disintegrant and filler are mixed, pulverize with micro jet, through mediating, add then and carry out granulation, drying, screening in the fluidized bed prilling dryer after sample analysis makes the water dispersible granules that contains the bactericidal composition of mebenil and tricyclazole of the present invention.
Six of technical scheme of the present invention, described bactericidal composition are microcapsule formulations, and the percentage by weight of component is:
Mebenil 0.1～50%
Tricyclazole 0.1～60%
Urea 5～20%
Formaldehyde 5～20%
Emulsifying dispersant 5～20%
Antifreezing agent 1～5%
Thickener 0.1～2%
Defoamer 0.1～0.8%
Water surplus
This bactericidal composition microcapsule formulations procedure of processing is: add urea and formaldehyde (amount of substance ratio be about 1: 1.5～2.0) in the there-necked flask of agitating device is housed, about pH value to 8～9 with the sodium hydroxide solution regulator solution, be warming up to 70～80 ℃ then, reaction obtains stable urea resin prepolymer.The former medicine of getting a certain amount of mebenil and tricyclazole is dissolved in the cyclohexane, and adds emulsifying dispersant in solution, follows vigorous stirring, and being made into the aqueous solution that contains emulsifying dispersant is the O/W type stable emulsion of water.Above-mentioned urea resin prepolymer is added in the emulsion, regulate the pH value, polymerization reaction take place under the acid catalysis condition is wrapped oil phase substance, forms microcapsule granule.Slowly heat up, solidify, temperature is controlled at 40～50 ℃, hardening time 1h.Select to add an amount of auxiliary agent, the microcapsule suspending agent that gets final product stablely.
Described emulsifier is selected from any one or more mixtures formed with arbitrary proportion in calcium dodecyl benzene sulfonate and aliphatic acid polyethenoxy ether, alkylphenol polyoxyethylene sulfosuccinate, styryl phenol APEO, polyoxyethylene nonylphenol ether, castor oil polyoxyethylene ether, aliphatic acid polyethenoxy base ester, the polyoxyethylene aliphatic alcohol ether.
Described dispersant is selected from one or more in polycarboxylate, sodium lignin sulfonate, alkylphenol polyoxyethylene formaldehyde condensation products sulphate, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, aliphatic acid polyethenoxy ether, polyoxyethylene carboxylate, the fatty acid glyceride APEO.
Described solvent is any one or more mixed solvents formed with arbitrary proportion in dimethylbenzene or biodiesel, toluene, diesel oil, methyl alcohol, ethanol, n-butanol, isopropyl alcohol, turpentine oil, solvent naphtha, dimethyl formamide, dimethyl sulfoxide (DMSO), the water equal solvent.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, calcium dodecyl benzene sulfonate, Nekal BX, wetting and penetrating agent F, alkylnaphthalene sulfonate, alkylphenol ethoxylate, polyoxyethylene triphenylethylene phosphenylic acid salt, spaonin powder, silkworm excrement, the soapberry powder.
Described synergist is meant to have the medicament of enhancing penetration, wetting extended capability, knock down insect speed, improve the resistance of rainwater washing against power of agricultural chemicals, thereby improve a class safety, environmental protection of agricultural insecticide, bactericidal effect, the New-type adjuvant of nontoxic, noresidue, optional in organic silicon pesticide synergist ZC-650 or organic silicon pesticide bleeding agent spreading agent Agrowet810c, agricultural organic silicon pesticide synergist Silwet408, azone any.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, aluminium chloride, citric acid, succinic acid, the sodium bicarbonate.
Described thickener is selected from: one or more in xanthans, CMC, hydroxyethylcellulose, methylcellulose, Magnesiumaluminumsilicate, the polyvinyl alcohol.
Described antimicrobial is selected from: one or both in Sodium Benzoate, sodium salicylate, the sodium sorbate.
Described stabilizing agent is selected from: a kind of in sodium citrate, the resorcinol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, diethylene glycol (DEG), the triethylene glycol.
Described defoamer is selected from: silicone oil, silicone compound, C
10-20Saturated fat acid compounds, C
8-10In aliphatic alcohols compound and the polyoxyethylene glycerol ether one or more.
Described emulsifying dispersant comprises: wetting agent, dispersant, stabilizing agent, thickener, defoamer and antifreezing agent etc.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
The invention has the beneficial effects as follows:
1, the used mebenil of the present invention is based on protective effect, has more weak therapeutic action concurrently.Tricyclazole is the triazole bactericidal agent of strong interior absorption, has very strong treatment and protective effect, the two mechanism of action difference, and being mixed mutually can not produce conflict, but Synergistic reduces dosage, reduces cost.At present mebenil and tricyclazole composite do not have report as yet.
2, two kinds of composite bactericide have double action mechanism, delay the drug-fast generation of germ.
3, reduced the agricultural chemicals usage amount, strengthened friendly environment.
Application Example
Further the present invention is made an explanation by following examples, but can not limit the scope of the invention.
Example of formulations 1:
Mebenil 0.1g, tricyclazole 60g, lignosulfonates 15g, sodium citrate 0.5g, xanthans 0.3g, ethylene glycol 1g, Sodium Benzoate 0.6g, silicone oil 0.5g, water surplus.Make 60.1% mebenil tricyclazole suspending agent according to above-mentioned suspending agent preparation method.
Example of formulations 2:
Mebenil 5g, tricyclazole 50g, lignosulfonates 10g, sodium citrate 0.5g, xanthans 0.3g, ethylene glycol 1g, Sodium Benzoate 0.6g, silicone oil 0.5g, water surplus.Make 55% mebenil tricyclazole suspending agent according to above-mentioned suspending agent preparation method.
Example of formulations 3:
Mebenil 15g, tricyclazole 35g, lignosulfonates 7g, sodium citrate 0.5g, xanthans 0.3g, ethylene glycol 1g, Sodium Benzoate 0.6g, silicone oil 0.5g, water surplus.Make 50% mebenil tricyclazole suspending agent according to above-mentioned suspending agent preparation method.
Example of formulations 4:
Mebenil 25g, tricyclazole 20g, lignosulfonates 7g, sodium citrate 0.5g, xanthans 0.3g, ethylene glycol 1g, Sodium Benzoate 0.6g, silicone oil 0.5g, water surplus.Make 45% mebenil tricyclazole suspending agent according to above-mentioned suspending agent preparation method.
Example of formulations 5:
Mebenil 40g, tricyclazole 10g, lignosulfonates 10g, sodium citrate 0.5g, xanthans 0.3g, ethylene glycol 1g, Sodium Benzoate 0.6g, silicone oil 0.5g, water surplus.Make 50% mebenil tricyclazole suspending agent according to above-mentioned suspending agent preparation method.
Example of formulations 6:
Mebenil 50g, tricyclazole 0.1g, lignosulfonates 10g, sodium citrate 0.5g, xanthans 0.3g, ethylene glycol 1g, Sodium Benzoate 0.6g, silicone oil 0.5g, water surplus.Make 50.1% mebenil tricyclazole suspending agent according to above-mentioned suspending agent preparation method.
Example of formulations 7:
Mebenil 0.1g, tricyclazole 60g, polyoxyethylene nonylphenol ether 8g, n-butanol 10g, sodium citrate 0.5g, ethylene glycol 1g, silicone oil 0.5g, xanthans 0.3g, Sodium Benzoate 0.6g, water surplus.Make 60.1% mebenil tricyclazole aqueous emulsion according to above-mentioned method for producing aqueous emulsion.
Example of formulations 8:
Mebenil 5g, tricyclazole 50g, polyoxyethylene nonylphenol ether 5g, n-butanol 8g, sodium citrate 0.5g, ethylene glycol 1g, silicone oil 0.5g, xanthans 0.3g, Sodium Benzoate 0.6g, water surplus.Make 55% mebenil tricyclazole aqueous emulsion according to above-mentioned method for producing aqueous emulsion.
Example of formulations 9:
Mebenil 15g, tricyclazole 35g, polyoxyethylene nonylphenol ether 5g, n-butanol 8g, sodium citrate 0.5g, ethylene glycol 1g, silicone oil 0.5g, xanthans 0.3g, Sodium Benzoate 0.6g, water surplus.Make 50% mebenil tricyclazole aqueous emulsion according to above-mentioned method for producing aqueous emulsion.
Example of formulations 10:
Mebenil 25g, tricyclazole 20g, polyoxyethylene nonylphenol ether 5g, n-butanol 8g, sodium citrate 0.5g, ethylene glycol 1g, silicone oil 0.5g, xanthans 0.3g, Sodium Benzoate 0.6g, water surplus.Make 45% mebenil tricyclazole aqueous emulsion according to above-mentioned method for producing aqueous emulsion.
Example of formulations 11:
Mebenil 40g, tricyclazole 10g, polyoxyethylene nonylphenol ether 5g, n-butanol 8g, sodium citrate 0.5g, ethylene glycol 1g, silicone oil 0.5g, xanthans 0.3g, Sodium Benzoate 0.6g, water surplus.Make 50% mebenil tricyclazole aqueous emulsion according to above-mentioned method for producing aqueous emulsion.
Example of formulations 12:
Mebenil 50g, tricyclazole 0.1g, polyoxyethylene nonylphenol ether 5g, n-butanol 8g, sodium citrate 0.5g, ethylene glycol 1g, silicone oil 0.5g, xanthans 0.3g, Sodium Benzoate 0.6g, water surplus.Make 50.1% mebenil tricyclazole aqueous emulsion according to above-mentioned method for producing aqueous emulsion.
Example of formulations 13:
Mebenil 0.1g, tricyclazole 60g, dimethyl sulfoxide (DMSO) 10g, aliphatic acid polyethenoxy ether 5g, sodium citrate 2g, organosilicon auxiliary agent 2g, water surplus according to above-mentioned microemulsion processing way, makes 60.1% mebenil tricyclazole microemulsion.
Example of formulations 14:
Mebenil 5g, tricyclazole 50g, dimethyl sulfoxide (DMSO) 8g, aliphatic acid polyethenoxy ether 5g, sodium citrate 2g, organosilicon auxiliary agent 2g, water surplus according to above-mentioned microemulsion processing way, makes 55% mebenil tricyclazole microemulsion.
Example of formulations 15:
Mebenil 15g, tricyclazole 35g, dimethyl sulfoxide (DMSO) 10g, aliphatic acid polyethenoxy ether 5g, sodium citrate 2g, organosilicon auxiliary agent 2g, water surplus according to above-mentioned microemulsion processing way, makes 50% mebenil tricyclazole microemulsion.
Example of formulations 16:
Mebenil 25g, tricyclazole 20g, dimethyl sulfoxide (DMSO) 10g, aliphatic acid polyethenoxy ether 5g, sodium citrate 2g, organosilicon auxiliary agent 2g, water surplus according to above-mentioned microemulsion processing way, makes 45% mebenil tricyclazole microemulsion.
Example of formulations 17:
Mebenil 40g, tricyclazole 10g, dimethyl sulfoxide (DMSO) 10g, aliphatic acid polyethenoxy ether 5g, sodium citrate 2g, organosilicon auxiliary agent 2g, water surplus according to above-mentioned microemulsion processing way, makes 50% mebenil tricyclazole microemulsion.
Example of formulations 18:
Mebenil 0.1g, tricyclazole 60g, lignosulfonates 10g, calcium dodecyl benzene sulfonate 5g, Nekal BX 3g, the diatomite surplus according to above-mentioned wetting powder processing method, makes 60.1% mebenil tricyclazole wettable powder.
Example of formulations 19:
Mebenil 5g, tricyclazole 50g, lignosulfonates 6g, calcium dodecyl benzene sulfonate 5g, the diatomite surplus according to above-mentioned wetting powder processing method, makes 55% mebenil tricyclazole wettable powder.
Example of formulations 20:
Mebenil 15g, tricyclazole 35g, lignosulfonates 5g, calcium dodecyl benzene sulfonate 3g, Nekal BX 3g, the diatomite surplus according to above-mentioned wetting powder processing method, makes 50% mebenil tricyclazole wettable powder.
Example of formulations 21:
Mebenil 25g, tricyclazole 20g, lignosulfonates 6g, calcium dodecyl benzene sulfonate 3g, Nekal BX 3g, the diatomite surplus according to above-mentioned wetting powder processing method, makes 45% mebenil tricyclazole wettable powder.
Example of formulations 22:
Mebenil 40g, tricyclazole 10g, lignosulfonates 10g, calcium dodecyl benzene sulfonate 6g, Nekal BX 3g, the diatomite surplus according to above-mentioned wetting powder processing method, makes 50% mebenil tricyclazole wettable powder.
Example of formulations 23:
Mebenil 0.1g, tricyclazole 60g, sodium lignin sulfonate 10g, calcium dodecyl benzene sulfonate 8g, urea 3g, the bentonite surplus according to above-mentioned water dispersible granules processing method, makes 60.1% mebenil tricyclazole water dispersible granule.
Example of formulations 24:
Mebenil 5g, tricyclazole 50g, sodium lignin sulfonate 8g, calcium dodecyl benzene sulfonate 5g, urea 3g, the bentonite surplus according to above-mentioned water dispersible granules processing method, makes 55% mebenil tricyclazole water dispersible granule.
Example of formulations 25:
Mebenil 15g, tricyclazole 35g, sodium lignin sulfonate 5g, calcium dodecyl benzene sulfonate 5g, urea 3g, the bentonite surplus according to above-mentioned water dispersible granules processing method, makes 50% mebenil tricyclazole water dispersible granule.
Example of formulations 26:
Mebenil 25g, tricyclazole 20g, sodium lignin sulfonate 8g, calcium dodecyl benzene sulfonate 5g, urea 3g, the bentonite surplus according to above-mentioned water dispersible granules processing method, makes 45% mebenil tricyclazole water dispersible granule.
Example of formulations 27:
Mebenil 50g, tricyclazole 0.1g, sodium lignin sulfonate 10g, calcium dodecyl benzene sulfonate 3g, urea 3g, the bentonite surplus according to above-mentioned water dispersible granules processing method, makes 50.1% mebenil tricyclazole water dispersible granule.
Example of formulations 28:
Mebenil 0.1g, tricyclazole 60g,, urea 8g, formaldehyde 10g, lignosulfonates 5g, lauryl sodium sulfate 5g, ethylene glycol 5g, xanthans 1g, silicone oil 0.5g, water surplus makes 60.1% mebenil tricyclazole microcapsule formulations according to above-mentioned microcapsule formulations processing way.
Example of formulations 29:
Mebenil 5g, tricyclazole 50g,, urea 8g, formaldehyde 10g, lignosulfonates 5g, lauryl sodium sulfate 5g, ethylene glycol 5g, xanthans 1g, silicone oil 0.5g, water surplus makes 55% mebenil tricyclazole microcapsule formulations according to above-mentioned microcapsule formulations processing way.
Example of formulations 30:
Mebenil 15g, tricyclazole 35g,, urea 8g, formaldehyde 10g, lignosulfonates 5g, lauryl sodium sulfate 5g, ethylene glycol 5g, xanthans 1g, silicone oil 0.5g, water surplus makes 50% mebenil tricyclazole microcapsule formulations according to above-mentioned microcapsule formulations processing way.
Example of formulations 31:
Mebenil 25g, tricyclazole 20g,, urea 8g, formaldehyde 10g, lignosulfonates 5g, lauryl sodium sulfate 5g, ethylene glycol 5g, xanthans 1g, silicone oil 0.5g, water surplus makes 45% mebenil tricyclazole microcapsule formulations according to above-mentioned microcapsule formulations processing way.
Example of formulations 32:
Mebenil 40g, tricyclazole 10g,, urea 8g, formaldehyde 10g, lignosulfonates 5g, lauryl sodium sulfate 5g, ethylene glycol 5g, xanthans 1g, silicone oil 0.5g, water surplus makes 50% mebenil tricyclazole microcapsule formulations according to above-mentioned microcapsule formulations processing way.
Application Example
The different proportioning co-toxicities of tricyclazole with mebenil
1 materials and methods
The design 1.1 material and medicament are mixed
Test medicine is 90% tricyclazole, the former medicine of 95% mebenil; For the examination pathogen is rice blast.Examination is made as 50%, tricyclazole according to tricyclazole and mebenil total active constituent content that is mixed: it is that 5 ratios such as 25%+25%, 20%+30%, 12.5%+37.5%, 10%+40%, 83%+41.7% are mixed that mebenil is established 1: 1,1: 1.5,1: 3,1: 4,1: 5 in former medicine mass ratio.
1.2 experimental scheme
Take by weighing the combination that is mixed of an amount of mebenil, the former medicine of tricyclazole, 5 tricyclazole mebenils respectively, fully vibration makes its dissolving in the sterilization triangular flask that adds 3mL watery hydrochloric acid in advance, and adding an amount of sterile water, to make 500 each 50mL of μ g/mL mother liquor standby.On the basis of preliminary experiment, respectively be mixed combination and tricyclazole, mebenil of tricyclazole mebenil respectively to be established 5 concentration gradients such as 5,10,20,40 and 80 μ g/g, and make blank with the watery hydrochloric acid of same concentrations, each is handled and repeats 3 times.
1.3 synergistic effect is measured
The employing growth rate method is measured, and every processing repeats 3 times, calculates relative inhibition, virulence regression equation, EC that each is handled
50, obtain the coefficient of synergism (SR) that each is handled with the Wadley method, carry out the synergistic effect evaluation.Concrete data see Table 1.
The tricyclazole mebenil mixture of the different proportionings of table 1 suppresses virulence and synergistic effect to rice blast
2 results and analysis
Each mixture synergism coefficient that tricyclazole and mebenil are mixed is all greater than 1, but tricyclazole: 1: 3 combination S R value that is mixed of mebenil is up to 1.89, greater than 1.5, shows as synergistic function, remaining 4 be mixed combination S R value all less than 1.5 greater than 1, show as summation action.
3 field trials are measured
Handle chemical control rice sheath blight disease field control effectiveness test:
Control time, number of times and method:
Investigation state of an illness radix before the dispenser for the first time carried out the preventive effect investigation in 18 days behind the last medicine.According to rice leaf sheath and the classification of blade extent of injury, be unit with the strain during investigation, diagonal 5 samplings in every sub-district are investigated 2 clumps at every, look into 10 clumps altogether, write down total strain number, diseased plant number and sick progression.
Grade scale:
0 grade: complete stool is anosis;
1 grade: quaterfoil and following each leaf sheath thereof, blade morbidity (is first leaf with sword-like leave);
3 grades: the 3rd blade and following each leaf sheath thereof, blade morbidity;
5 grades: second blade and following each leaf sheath thereof, blade morbidity;
7 grades: sword-like leave blade and following each leaf sheath thereof, blade morbidity;
9 grades: the complete stool morbidity, withered ahead of time.
Computing formula:
Each handles control rice blast field control effectiveness test table as a result table 2
Interpretation of result:
As shown in Table 2, tricyclazole and mebenil are under 1: 3 proportioning, and be remarkable for the effect of rice sheath blight disease.The effect of its high concentration treatment region obviously is better than the low concentration treatment region under the same proportioning.Investigation in 18 days after the 2nd medication, the highest preventive effect can reach about 85%.Simultaneously, its complex preparation has obvious synergistic effect.Under recommended dose, use crop safety.
Each processing of table 3 prevents and treats stripe rust of wheat field control effectiveness test table as a result
Interpretation of result:
As shown in Table 3, tricyclazole and mebenil are under 1: 3 proportioning, and be remarkable for the effect of stripe rust of wheat.The effect of its high concentration treatment region obviously is better than the low concentration treatment region under the same proportioning.Investigation in 18 days behind its 2nd medicine, the highest preventive effect can reach about 87%.Simultaneously, its complex preparation has obvious synergistic effect.Under recommended dose, use, be suitable for promoting demonstration crop safety.At the stripe rust of wheat initial stage of origination, the control of dispenser in time can obtain ideal effect.Should avoid repeating excessive use in use, to delay the drug-fast generation of germ.
Claims (6)
1. bactericidal composition, it is characterized in that: contain two kinds of active components of mebenil and tricyclazole, wherein the weight ratio of mebenil and tricyclazole is 0.1～50: 0.1～60.
2. bactericidal composition according to claim 1 is characterized in that: the more excellent weight ratio of mebenil and tricyclazole is 5～50: 5～60.
3. bactericidal composition according to claim 1 is characterized in that: the percentage by weight that mebenil and tricyclazole are accumulated shared preparation is 10～83%.
4. bactericidal composition according to claim 1 is characterized in that: mebenil and tricyclazole and auxiliary agent and cosolvent are re-dubbed any one formulation that allows on the agricultural chemicals.
5. bactericidal composition according to claim 1 is characterized in that: the formulation that can be processed into is suspending agent, aqueous emulsion, microemulsion, wetting powder, water dispersible granules and microcapsule formulations etc.
6. bactericidal composition according to claim 1 is characterized in that: can be used for preventing and treating multiple fungal diseases such as sigatoka, rice sheath blight disease, rice blast, wheat powdery mildew, wheat rust, leaf spot of peanut.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010100015719A CN102113493A (en) | 2010-01-03 | 2010-01-03 | Sterilization composite containing mepronil and tricyclazole |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010100015719A CN102113493A (en) | 2010-01-03 | 2010-01-03 | Sterilization composite containing mepronil and tricyclazole |
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| Publication Number | Publication Date |
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| CN102113493A true CN102113493A (en) | 2011-07-06 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2010100015719A Pending CN102113493A (en) | 2010-01-03 | 2010-01-03 | Sterilization composite containing mepronil and tricyclazole |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103385242A (en) * | 2012-05-12 | 2013-11-13 | 陕西汤普森生物科技有限公司 | Insecticidal composition comprising dicyclanil biological source |
| CN108064869A (en) * | 2018-01-03 | 2018-05-25 | 佛山市盈辉作物科学有限公司 | A kind of composition pesticide containing ferimzone and tricyclazole |
| CN111869661A (en) * | 2020-08-20 | 2020-11-03 | 蚌埠格润生物科技有限公司 | High-concentration tricyclazole suspending agent and preparation method thereof |
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- 2010-01-03 CN CN2010100015719A patent/CN102113493A/en active Pending
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| 吕山: "日本使用的杀菌剂混剂", 《农药》 * |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103385242A (en) * | 2012-05-12 | 2013-11-13 | 陕西汤普森生物科技有限公司 | Insecticidal composition comprising dicyclanil biological source |
| CN103385242B (en) * | 2012-05-12 | 2016-02-17 | 陕西汤普森生物科技有限公司 | A kind of Pesticidal combination containing CGA 183893 and biogenic substances |
| CN108064869A (en) * | 2018-01-03 | 2018-05-25 | 佛山市盈辉作物科学有限公司 | A kind of composition pesticide containing ferimzone and tricyclazole |
| CN111869661A (en) * | 2020-08-20 | 2020-11-03 | 蚌埠格润生物科技有限公司 | High-concentration tricyclazole suspending agent and preparation method thereof |
| CN111869661B (en) * | 2020-08-20 | 2023-01-24 | 蚌埠格润生物科技有限公司 | High-concentration tricyclazole suspending agent and preparation method thereof |
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Application publication date: 20110706 |