CN104137850A - Nematode killing composition containing iprodione and clothianidin - Google Patents
Nematode killing composition containing iprodione and clothianidin Download PDFInfo
- Publication number
- CN104137850A CN104137850A CN201410372489.5A CN201410372489A CN104137850A CN 104137850 A CN104137850 A CN 104137850A CN 201410372489 A CN201410372489 A CN 201410372489A CN 104137850 A CN104137850 A CN 104137850A
- Authority
- CN
- China
- Prior art keywords
- clothianidin
- iprodione
- nematicidal composition
- killing composition
- nematode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention relates to a nematode killing composition containing iprodione and clothianidin. The mass ratio of effective constituents of the iprodione to the clothianidin in the nematode killing composition is 1 to 50:50 to 1. The total mass of effective constituents of the iprodione and the clothianidin in a preparation accounts for 1% to 80% of the mass of the whole preparation and the remaining constituents are auxiliary constituents allowed to be used and accepted in pesticide. The dosage form of the nematode killing composition is emulsifiable concentrate, a suspending agent, wettable powder, water dispersible granules, emulsion in water, microemulsion, granules, microcapsules and an aqueous solution, and the nematode killing composition is suitable for preventing and treating parasitic nematodes and soil insects harmful to plant root systems and especially for preventing and treating parasitic nematodes on cereals, fruits and vegetables.
Description
Technical field
The present invention relates to agriculture chemical compounding technical field, particularly relate to a kind of nematicidal composition that contains iprodione and clothianidin.
Background technology
Nemas is by plant nematode invasion and attack and parasitogenic plant disease.The plant that is injured can grow because nutrition in intrusion nematode absorber affects normally; Secretion in nematode metabolic process also can stimulate cell and the tissue of host plant, causes plant deformity, makes the agricultural product underproduction and Quality Down.The comparatively serious nemas of China has root knot nematode disease, soybean cyst nematode, wheat anguina disease, sweep stem nematode, aphelenchoides besseyi disease, grain nematodosis, pine nematode, the oranges and tangerines of the various crop such as the peanut nematodosis etc. that partly punctures.
(Iprodione, chemistry 1-isopropylamine base formoxyl-3-(3,5-dichlorophenyl) hydantoins by name, CAS:36734-19-7) is dicarboximide class high-efficiency broad spectrum, contact killing type bactericide to iprodione.Iprodione energy Profilin kinases, controls the thin intracellular signal of many cell functions, comprises that carbohydrate is in conjunction with the interference effect that enters fungal cell's component.Therefore, it gets final product sprouting and the generation of Antifungi spore, also can suppress mycelial growth.Be applicable to prevent and treat the diseases such as crop early defoliation disease, gray mold, early blight such as multiple fruit tree, vegetables, melon and fruit class.
Clothianidin (clothianidin; CAS: 210880-92-5; 205510-53-8; Chemical name: (2-chloro-1 for (E)-1-, 3-thiazole-5-ylmethyl)-3-methyl-2-2-nitroguanidine) the anabasine insecticide of Shi You Beyer Co., Ltd and Japanese Takeda Wu Tian company joint development, clothianidin is the novel pesticide of a class highly effective and safe, high selectivity, its effect is similar with nAChR, have tag, stomach toxicity and systemic activity.Be mainly used on paddy rice, vegetables, fruit tree and other crops anti-ly eliminating aphis, the insecticide of Semiptera, coleoptera, diptera and some Lepidoptera class pest such as leafhopper, thrips, plant hopper, there is efficient, wide spectrum, consumption is few, toxicity is low, the drug effect lasting period long, to crop without poisoning, use safety, with conventional pesticide without advantages such as cross resistances, having remarkable interior suction and osmosis, is the another kind that substitutes high malicious organophosphorous pesticide.Its novel structure, special, performance is compared more excellent with traditional nicotinic insecticide.Crops are the various diseases that caused by seed and Soil infection of easy infection in plantation and process of growth, such as bakanae disease of rice and banded sclerotial blight, wheat sharp eyespot, cotton seedling blight, Roots of Peanut maize ear rot, root rot, Causal Organism of Maize Basal Stalk etc.Seed-borne fungi is diseases induced first dip-dye source, and it can cause infecting, occur, spread and endangering of disease in the season of growth; And after seed-borne disease generation, the growth of crop, growth, yield and quality are all had a significant impact.
In the real process of agricultural production, using chemical agent is the most effectively means of control plant pest, but the problem the most easily producing by chemical control insect is the generation of pest resistance to insecticide.And long-term use single chemical insecticide continuously high dose, easily cause the series of problems such as residual, environmental pollution of medicament.We are on the basis of lab screening and field trial, filter out iprodione and clothianidin is composite, have improve control efficiency, extend the optimum period for applying fertilizer, reduce dosage, reduce poisoning, reduce residual, delay actively feature such as pest resistance and drug-fast generation and development etc., and about iprodione and the composite nematicidal composition of clothianidin and apply and there is no at present people and reported.
Summary of the invention
Based on above situation, the object of the invention is to provide a kind of new and effective agricultural chemicals nematicidal composition.Be applicable to parasitic nematode and soil insect, especially Cereal, the fruit of control harm root system of plant, the parasitic nematode on vegetables.
Technical scheme of the present invention realizes by following measures:
A kind of nematicidal composition that contains iprodione and clothianidin, in this nematicidal composition, the mass ratio of active ingredient iprodione and clothianidin is 1～50: 50～1, described nematicidal composition of the present invention is through toxicity test experimental verification, the mass ratio of iprodione and clothianidin is 1～10: 10～1 o'clock, synergistic effect was better.
The formulations of pesticide that described nematicidal composition of the present invention can be prepared are missible oil, suspending agent, wetting powder, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations, aqua.Iprodione and the clothianidin gross mass in preparation accounts for 1%～80% of the whole quality of the pharmaceutical preparations, while wherein accounting for 1%～50%, and toxicity and residually reach good balance, cost is also lower.
The specific embodiments of the formulations of pesticide that nematicidal composition of the present invention is mixed with is as follows:
Described nematicidal composition is cream preparation, and the mass fraction of component is: 1～50 part of clothianidin; 1～50 part of iprodione; 10～30 parts of conventional emulsifiers; 20～50 parts of conventional solvents; 1～5 part of conventional synergist.The concrete production stage of this cream preparation is for first adding active ingredient clothianidin and iprodione in solvent the oily liquids that becomes transparent and homogeneous after adding again emulsifier, synergist to stir after dissolving completely, filling, can be made into the cream preparation of the present composition.
Described nematicidal composition is suspending agent, and the mass fraction of component is: 1～50 part of clothianidin; 1～50 part of iprodione; 5～20 parts of dispersants; 1～5 part of antifreezing agent; 0.1～2 part of thickener; 0.1～0.8 part of defoamer; 0～10 part of penetrating agent; 0.1～5 part of pH value conditioning agent; Water, surplus.The concrete production stage of this suspending agent is for first mixing other auxiliary agents, through high speed shear, mix, add active ingredient clothianidin and iprodione, in ball crusher, abrading-ball is 2～3 hours, make a diameter all below 5mm, can be made into the suspending agent preparation of the present composition.
Described nematicidal composition is wetting powder, and the mass fraction of component is: 1～50 part of clothianidin; 1～50 part of iprodione; 3～10 parts of dispersants; 1～5 part of wetting agent; Filler, surplus.The concrete production stage of this wetting powder is: by above-mentioned formula, active ingredient clothianidin is mixed with iprodione and dispersant, wetting agent and filler, uniform stirring in stirred tank, after airslide disintegrating mill, mixing, can be made into the wetting powder of the present composition.
Described nematicidal composition is water dispersible granules, and the mass fraction of component is: 1～50 part of clothianidin; 1～50 part of iprodione; 3～10 parts of dispersants; 1～10 part of wetting agent; 1～5 part of disintegrant; Filler surplus.The concrete production stage of this water dispersible granules is: by above-mentioned formula, active ingredient clothianidin is mixed with iprodione and dispersant, wetting agent, disintegrant and filler, with micro jet, pulverize, through mediating, then add and in fluidized bed prilling dryer, carry out granulation, dry, screening by sample analysis, can be made into the water dispersible granules of the present composition.
Described nematicidal composition is aqueous emulsion, and the mass fraction of component is: 1～50 part of clothianidin; 1～50 part of iprodione; 3～30 parts of emulsifier; 5～15 parts of solvents; 2～15 parts of stabilizing agents; 1～5 part of antifreezing agent; 0.1～8 part of defoamer; 0.2～2 part of thickener; Water, surplus.The concrete production stage of this aqueous emulsion is: first clothianidin and iprodione, solvent and emulsifier, cosolvent are added together, make to be dissolved into uniform oil phase; By part water, antifreeze, other the insecticides adjuvant such as antimicrobial mixes into uniform water; When reactor high speed stirs, oil phase is added to water, slowly add water until reach phase inversion point, open clipper and carry out high speed shear, and add remaining water, shear about half an hour, form the aqueous emulsion of oil-in-water type, can be made into the aqueous emulsion of the present composition.
Described nematicidal composition is microemulsion, and the mass fraction of component is: 1～50 part of clothianidin; 1～50 part of iprodione; 10～30 parts of emulsifier, 1～8 part of antifreezing agent, 0.5～10 part of stabilizing agent, 20～50 parts of conventional solvent cosolvents.Clothianidin and iprodione are dissolved completely with cosolvent, then add other compositions such as emulsifier, antifreezing agent stabilizing agent, evenly mix, finally add water, after fully stirring, can be made into microemulsion.
Described nematicidal composition is granule, and the mass fraction of component is: 1～50 part of clothianidin; 1～50 part of iprodione; 1～10 part of wetting dispersing agent; 0.1～5 part of thickener; 0.1～5 part of defoamer; Castor oil, surplus is supplied.Each components such as active ingredient clothianidin and iprodione, dispersant, stabilizing agent, defoamer and solvent are mixed in the ratio of formula, put into after the grinding of sand milling still, send in mixer for well-distribution and mix and get product.
Described nematicidal composition is microcapsule formulations, and the mass fraction of component is: 1～50 part of clothianidin; 1～50 part of iprodione; 5～20 parts, urea; 5～20 parts, formaldehyde; 5～20 parts of emulsifying dispersants; 1～5 part of antifreezing agent; 0.1～2 part of thickener; 0.1～0.8 part of defoamer; Water, surplus.In being housed, the there-necked flask of agitating device adds urea and formaldehyde (amount of substance ratio is about l:1.5～2.0), left and right, pH value to 8～9 with sodium hydroxide solution regulator solution, then be warming up to 70～80 ℃, reaction obtains stable urea resin prepolymer.The former medicine of getting a certain amount of clothianidin and iprodione is dissolved in cyclohexane, and adds emulsifying dispersant in solution, follows vigorous stirring, the O/W type stable emulsion that to be made into the aqueous solution of take containing emulsifying dispersant be water.Above-mentioned urea resin prepolymer is added in emulsion, regulate pH value, polymerization reaction take place under acid catalysis condition, is wrapped oil phase substance, forms microcapsule granule.Slowly heat up, solidify, temperature is controlled at 40～50 ℃, hardening time 1h.Selection adds appropriate auxiliary agent, the microcapsules that gets final product stablely.
Described nematicidal composition is aqua, and the mass fraction of component is: 1～50 part of clothianidin; 1～50 part of iprodione; 0.1～30 part of wetting dispersing agent; 2～8 parts of antifreezing agents; 0.1～1 part of defoamer; 0.1～3 part of thickener; 5～15 parts of spreader-stickers; Water, surplus is supplied.By active ingredient clothianidin and iprodione, dissolve completely with cosolvent, then add other compositions such as dispersant, antifreezing agent, defoamer, evenly mix, finally add water, after fully stirring, get final product to obtain finished product.
Wherein above-described emulsifier is selected from calcium dodecyl benzene sulfonate and aliphatic acid polyethenoxy ether, alkylphenol polyoxyethylene sulfosuccinate, styrylphenol polyoxyethylene ether, polyoxyethylene nonylphenol ether, castor oil polyoxyethylene ether, aliphatic acid polyethenoxy base ester, any or more than one any mixtures than forming in polyoxyethylene aliphatic alcohol ether.
Described solvent is dimethylbenzene or biodiesel, toluene, diesel oil, methyl alcohol, ethanol, n-butanol, isopropyl alcohol, turpentine-based vegetable oil code name is ND-45, solvent naphtha, dimethyl formamide, dimethyl sulfoxide (DMSO), one or more in water equal solvent are arbitrarily than the mixture forming.
It is LG-3, GY-D1252, GY-D1256, SNWGF-01 that described dispersant is selected from polycarboxylate code name, lignosulfonates code name is 201107,201108, alkylphenol polyoxyethylene methyl ether condensate sulfate, alkylsulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, polyoxyethylene carboxylate, aliphatic amine polyoxyethylene ether, one or more in fatty acid glyceride APEO.
Described wetting agent is selected from lauryl sodium sulfate, calcium dodecyl benzene sulfonate, and Nekal BX, moistening bleeding agent F, alkylbenzenesulfonate polyoxyethylene triphen is phosphenylic acid salt dimly, spaonin powder, silkworm excrement, one or more in soapberry powder.
Described disintegrant is selected from bentonite, urea, ammonium sulfate, aluminium chloride, citric acid, succinic acid, one or more in sodium bicarbonate.
Described thickener is selected from xanthans, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose, Magnesiumaluminumsilicate, in polyvinyl alcohol one or more.
Described stabilizing agent is selected from sodium citrate, a kind of in resorcinol.
Described antifreezing agent is selected from ethylene glycol, propane diols, one or more in glycerine.
Described defoamer is selected from silicone oil, silicone compound, C
10-20saturated fat acid compounds, C
8-10one or more of fatty alcohol.
Described filler is selected from kaolin, diatomite, bentonite, attapulgite, white carbon, starch, one or more in precipitated calcium carbonate.
The present invention be take the composition that active ingredient is clothianidin and iprodione and is had obvious nematocidal effect, delays the drug-fast generation in key, and has reduced and become to produce cost and use cost.
Embodiment
For making technical scheme of the present invention, object and advantage are clearer, and the present invention describes with following specific embodiment, but the present invention is not limited to these examples.The mode that effect experiment of the present invention adopts indoor biometrics and field trial to combine, if no special instructions, the ratio of below mentioning is all ratio of quality and the number of copies.
Embodiment: clothianidin proportioning co-toxicity experiments different from iprodione.
Test target: cucumber root-knot nematode
Evaluation method is liquid infusion method.First use the former medicine of acetone solution, according to the result of preliminary experiment, appropriate active component is made into several different proportionings, then it is stand-by with acetone, each processing to be diluted to respectively to several concentration gradients.In each hole of 96 orifice plates, inject 100ul, then add equivalent root-knot nematode suspension, at 25 ℃, place after one week by nematode survival number and death toll in each hole of microscopic counting dark place.
Drug effect computational methods: lethality (%)=dead borer population/(survival number+dead borer population) * 100.
The expection effect of mixture of active principles (be theoretical control efficiency, %) use Colby formula determine and with the effect comparison of observing:
Colby formula: E=X+Y-X*Y/100
E: iprodione working concentration is a in composition, the expection effect of the composition that clothianidin working concentration is b;
X: the expection effect that iprodione working concentration is a;
Y: the expection effect that clothianidin working concentration is b;
When the preventive effect of observing surpasses expection preventive effect, explanation has synergistic effect.
Form 1 is iprodione and the clothianidin Toxicity Determination result to cucumber root-knot nematode separately
Form 2 is the composite Toxicity Determination result to cucumber root-knot nematode of iprodione and clothianidin
Result of the test shows, under indoor conditions, clothianidin and iprodione all have higher activity to root-knot nematode, and further field control effectiveness test is carried out in suggestion, to evaluate its field practical application effect.
3, field trial control cucumber root-knot nematode
3.1 test method
Test in Qingdao Jimo and move wind shop vegetable field, root-knot nematode harm is serious.9 processing are established in test altogether, and employing applies mode to be carried out, and after chemicals treatment, takes the method for random sampling, the sampling of 5 of every communities, and every some random searching 2 strains, amount to l0 strain cucumber seedling, and cucumber root is dug out, and root-knot nematode hazard level is recorded in investigation.Investigation method is undertaken by pesticide field efficacy medicine test criterion.
Eelworm harm classification adopts pulls out strain percentage:
0 grade: without visible root nodule or pieces of an egg;
1 grade: root nodule total length accounts for total with 1%-24% of length;
2 grades: root nodule total length accounts for total with 25%-49% of length;
3 grades: root nodule total length accounts for total with 50%-74% of length;
4 grades: root nodule total length accounts for total with 75%-100% of length.
Disease index=∑ (diseases at different levels are with number * relative level numerical value)/(investigating total strain number * 4) * 100;
Control efficiency (%)=(1-(processes disease index/contrast disease index) * 100.
3.2 results and analysis
As can be seen from Table 2, the Mixed Pharmacy of different proportion, by different consumptions, carry out field experiment, after medicine, its control efficiency to cucumber root-knot nematode is better than contrasting medicament, fast with clothianidin and iprodione control root-knot nematode effect, efficiency time is long, and control efficiency is good, and effect increases progressively along with the increase of consumption.Can effectively control the harm of root-knot nematode to host, to the raising of quality of vegetable with increase production significantly, have stronger popularizing value.
To sum up described in indoor biometrics and field experiment result, of the present inventionly take clothianidin and iprodione and carry out composite nematicidal composition as active ingredient, nematode is shown to good control efficiency, to target crop safety, compare with single dose, nematicidal composition of the present invention has mechanism of action uniqueness, unit consumption is few, quick-acting is good, the plurality of advantages such as the lasting period is long, so research and development of the present invention and promotion conference produce very large economic worth, to vast vegetables, the protection tool of the increasing both production and income of the peasant household in fruit tree producing region and local environment is of great significance.
Claims (4)
1. a nematicidal composition that contains iprodione and clothianidin, in this nematicidal composition, the mass ratio of active ingredient iprodione and clothianidin is 1～50: 50～1.
2. nematicidal composition according to claim 1, is characterized in that: iprodione and the clothianidin gross weight in preparation accounts for 1%～80% of the whole quality of the pharmaceutical preparations.
3. nematicidal composition according to claim 2, is characterized in that: iprodione and the clothianidin gross weight in preparation accounts for 1%～50% of the whole quality of the pharmaceutical preparations.
4. according to the nematicidal composition described in claim 1 or 2 or 3, it is characterized in that: the formulation of this Pesticidal combination is missible oil, suspending agent, wetting powder, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations, aqua.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410372489.5A CN104137850A (en) | 2014-07-31 | 2014-07-31 | Nematode killing composition containing iprodione and clothianidin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410372489.5A CN104137850A (en) | 2014-07-31 | 2014-07-31 | Nematode killing composition containing iprodione and clothianidin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104137850A true CN104137850A (en) | 2014-11-12 |
Family
ID=51847334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410372489.5A Pending CN104137850A (en) | 2014-07-31 | 2014-07-31 | Nematode killing composition containing iprodione and clothianidin |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104137850A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104621169A (en) * | 2015-03-04 | 2015-05-20 | 山东科大创业生物有限公司 | Compound preparation for killing nematodes |
| CN104757014A (en) * | 2015-04-16 | 2015-07-08 | 广东中迅农科股份有限公司 | Pesticide composition containing iprodione and thiamethoxam |
| CN104770389A (en) * | 2015-04-16 | 2015-07-15 | 广东中迅农科股份有限公司 | Pesticide composition for preventing and controlling meloidogyne |
| CN113647396A (en) * | 2021-09-07 | 2021-11-16 | 四川眉山凯尔化工有限公司 | Composition for killing nematodes and preparation method thereof |
-
2014
- 2014-07-31 CN CN201410372489.5A patent/CN104137850A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104621169A (en) * | 2015-03-04 | 2015-05-20 | 山东科大创业生物有限公司 | Compound preparation for killing nematodes |
| CN104621169B (en) * | 2015-03-04 | 2017-01-04 | 山东科大创业生物有限公司 | A kind of nematicide combination preparation |
| CN104757014A (en) * | 2015-04-16 | 2015-07-08 | 广东中迅农科股份有限公司 | Pesticide composition containing iprodione and thiamethoxam |
| CN104770389A (en) * | 2015-04-16 | 2015-07-15 | 广东中迅农科股份有限公司 | Pesticide composition for preventing and controlling meloidogyne |
| CN104770389B (en) * | 2015-04-16 | 2018-02-16 | 广东中迅农科股份有限公司 | A kind of composition pesticide for being used to prevent and treat root-knot nematode |
| CN104757014B (en) * | 2015-04-16 | 2018-05-18 | 广东中迅农科股份有限公司 | A kind of composition pesticide containing iprodione and Diacloden |
| CN113647396A (en) * | 2021-09-07 | 2021-11-16 | 四川眉山凯尔化工有限公司 | Composition for killing nematodes and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104585190A (en) | Nematicide composition containing abamectin and fluopyram | |
| CN107333790A (en) | A kind of Herbicidal combinations of killing combination containing thiencarbazone-methymesotrione and S-metolachlor | |
| CN103238618A (en) | Seed treating agent composition containing clothianidin | |
| CN102113496B (en) | Bactericidal composition containing dicyclanil and methomyl | |
| CN103636661A (en) | Insecticide composition containing bifenthrin and flonicamid | |
| CN104488921A (en) | Nematicidal composition containing fluensulfone and abamectin | |
| CN104522049A (en) | Nematicidal composition containing fluensulfone and fosthiazate | |
| CN104137850A (en) | Nematode killing composition containing iprodione and clothianidin | |
| CN103190433A (en) | Pesticide composition with spirotetramat and dinotefuran | |
| CN102972430A (en) | Insecticidal composition containing thiamethoxam and acetamiprid | |
| CN104054736A (en) | Insecticidal combination containing sulfoxaflor and spirotetramat | |
| CN104585230A (en) | Nematicidal composition containing fosthiazate and fluopyram | |
| CN104488941A (en) | Nematicidal composition containing fluensulfone and iprodione | |
| CN104137849A (en) | Nematode killing composition containing iprodione and dinotefuran | |
| CN103918693A (en) | Bactericidal composition containing prothioconazole and prochloraz | |
| CN104488890A (en) | Nematicidal compound containing fluensulfone and fludioxonil | |
| CN104488889A (en) | Nematicidal composition containing fluensulfone and fluopyram | |
| CN103719139A (en) | Insecticide composition containing dinotefuran and diafenthiuron | |
| CN103125488A (en) | Weedicide composition containing dimethenamid-p and pendimethalin | |
| CN103190407A (en) | Insecticide composition containing methoxyfenozide and chlorfenapyr | |
| CN104542619A (en) | Nematode killing composition containing fluensulfone and fluopyram | |
| CN104542674A (en) | Nematicidal compound containing fluensulfone and thiacloprid | |
| CN104542681A (en) | Nematicidal compound containing fluensulfone and dinotefuran | |
| CN104542683A (en) | Nematicidal compound containing fluensulfone and thiamethoxam | |
| CN104054743A (en) | Insecticidal combination containing sulfoxaflor and dinotefuran |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20141112 |