CN102091233B

CN102091233B - Traditional Chinese medicinal composition chilblain ointment for treating chilblain

Info

Publication number: CN102091233B
Application number: CN 201110022036
Authority: CN
Inventors: 张汉卿
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-01-14
Filing date: 2011-01-14
Publication date: 2013-03-13
Anticipated expiration: 2031-01-14
Also published as: CN102091233A

Abstract

The invention discloses traditional Chinese medicinal composition chilblain ointment for treating chilblain. In the chilblain ointment, aiming at the causes of the chilblain by external affection by pathogenic cold, stagnation of blood vessels and stagnation of main and collateral channels, traditional Chinese medicines such as eucommia bark, golden thread, platycodon root, tangerine peel, old radish, tuber bletillae and rhubarb are selected, and are blended to form paste with a proper amount of black sesame oil, and the paste is applied to wounds to nourish and strengthen body, strengthen body resistance and archaeus, warm meridian for activating yang, disperse cold for eliminating blood stasis, promote blood circulation, eliminate swelling, diminish inflammation and relieve pain. Clinical tests prove that the traditional Chinese medicinal composition chilblain ointment has quick response and obvious curative effect, does not have toxic or side effect, and is worthy of being popularized and used clinically.

Description

A kind of Chinese medicine composition kibe ointment for the treatment of chilblain

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicinal ointment for the treatment of chilblain.

Background technology

Chilblain is that body is subject to occurring in tip position localized erythema diseases associated with inflammation after the cold invasion and attack.Common infringement is the edematous erythema of limitation blood stasis mulberry protuberance, indefinite border, and vesicle can occur in severe patient, and break rear formation erosion or ulcer have pigmentation or atrophic scar after more, itch and are heated rear aggravation.Mainly with the back of the hand, finger, toes, instep, buccal, auricle, nose damaged.Chilblain is commonly encountered diseases, the frequently-occurring disease in clinically winter, brings the misery to the patient except pruritus pain, and skin lesion is mainly in acra, face, and severe patient can affect local function and beauty treatment.Though the medicine of existing treatment chilblain has certain curative effect on the market, onset is slower, and therapeutic effect is poor, and local excitation is larger.

Summary of the invention

The reason that motherland's medical evidence, chilblain form is to be subjected to the cold-evil outward, and blood vessels are not smooth, due to meridians stagnate, the objective of the invention is the cause of disease that forms for chilblain, provides a kind of onset very fast, the kibe ointment that is formed by traditional Chinese medicine that therapeutic effect is good.

The objective of the invention is to be achieved through the following technical solutions, the Chinese medicine composition kibe ointment of this treatment chilblain is made by the raw material of Chinese medicine of following weight fraction: Cortex Eucommiae 2-7 divides, Rhizoma Coptidis 3-9 divides, Radix Platycodonis 5-15 divides, Pericarpium Citri Reticulatae 5-15 divides, withered trailing plants 15-25 divide, Pseudobulbus Bletillae (Rhizoma Bletillae) 3-9 divides, Radix Et Rhizoma Rhei 5-15 divides, Semen Sesami Nigrum oil is an amount of.

The raw material of Chinese medicine that the Chinese medicine composition kibe ointment of this treatment chilblain is divided by following optimum weight is made: the Cortex Eucommiae 5 minutes, Rhizoma Coptidis 6 minutes, Radix Platycodonis 10 minutes, Pericarpium Citri Reticulatae 10 minutes, withered trailing plants 20 minutes, Pseudobulbus Bletillae (Rhizoma Bletillae) 6 minutes, Radix Et Rhizoma Rhei 10 minutes, Semen Sesami Nigrum oil an amount of.

Prepare routinely the unguentum method, above each raw material of Chinese medicine is made powder, be mixed into unguentum with Semen Sesami Nigrum oil.

The pharmacology of each crude drug: Cortex Eucommiae invigorating the liver and kidney, bone and muscle strengthening, invigorating the spleen and replenishing QI; The flat property of medicine of Radix Platycodonis, the pain of dispelling evacuation of pus; Pericarpium Citri Reticulatae is warm in nature, and bath is wet; The withered trailing plants diuresis detumescent in ground; Pseudobulbus Bletillae (Rhizoma Bletillae) astringing to arrest bleeding, detumescence and promoting granulation; Radix Et Rhizoma Rhei is let out fire detoxifcation, relieving constipation by what; The Rhizoma Coptidis heat-clearing and toxic substances removing is alleviated heart stomach upset and the preventing or arresting vomiting that causes because of pain with each medicine compatibility among the we; Semen Sesami Nigrum oil adjust each drug effect, nourish burn wound.

Clinical data

1, physical data

(1) to damage typical predilection site be buccal, auricle, ear-lobe, nose, finger, instep, heel to case inclusion criteria chilblain.The skin lesion characteristics: the edematous erythema of limitation blood stasis mulberry or red protuberance, indefinite border forms erosion or ulcer after serious generation vesicle is broken.Morbidity when temperature is low at the beginning of annual winter autumn Mo, spring.Get rid of that cardiorenal function is complete, the liver function infringement is heavier, lupus erythematosus, scleroderma etc., severe hypotension, anemia of pregnant woman, life-time service immunosuppressant and corticosteroid patient.

(2) MethodsThe cases enrolled is selected case 238 routine random packet treatments according to above case inclusion criteria.Treatment group 120 examples, male 65 examples, women 55 examples; Age is at 13～71 years old, average 35.5 years old; Red and swollen scope is less than 2cm person's 9 examples, and 2～8cm person, 92 examples are greater than 8cm person's 18 examples; 1～15 of red and swollen number, average 7.5, person's 10 examples that have the skin lesion.Matched group 118 examples, male 66 examples, women 52 examples; Age is at 14～75 years old, average 38.5 years old; Red and swollen scope is less than 2cm person's 8 examples, 2～8cm person, 92 examples, and greater than 8cm person's 14 examples, 1～16 of red and swollen number, average 7.5, person's 8 examples that have the skin lesion.Two group differences have comparability without significance (P＞0.05).

2, the Therapeutic Method treatment group is applied kibe ointment of the present invention, matched group external application 10% Camphora

Ointment, two groups of simultaneously whole body winter protection, warming, balanced nutritious, simultaneously conventional therapies such as oral nicotinic acid tablet, vitamin E ball.

3, observational technique two all rear observe the curative effect, it is to cure that redness is eliminated fully; Red and swollen decreased number or scope are reduced to effectively.Take the case of curing as radix, Second Year is added up relapse rate winter.

4, therapeutic effect treatment group 120 examples are cured 99 examples, effective 114 examples, and Second Year recurs 23 examples; Matched group 118 examples are cured 61 examples, effective 79 examples, and Second Year recurs 38 examples.Curative effect compares: treatment group cure rate 82.50%, effective percentage 95.00%, relapse rate 23.23%; Matched group cure rate 51.69%, effective percentage 66.39%, the second relapse rate 62.23%.Two groups relatively, and treatment group obviously is better than matched group, and significant difference (P＜0.05) is arranged

Model case

Case 1: Liu Hongmei, the woman does individual business, and both hands and two cheeks all belong to year after year habitual serious cold injury, have reached the more than ten years, the drug of topical application on January 12 in 2009, to crevasse in five days on the 17th healing, red and swollen pimple disappears and cures fully.

The specific embodiment

Embodiment one: get Cortex Eucommiae 5g, Rhizoma Coptidis 6g, Radix Platycodonis 10g, Pericarpium Citri Reticulatae 10g, withered trailing plants 18g, Pseudobulbus Bletillae (Rhizoma Bletillae) 6g, Radix Et Rhizoma Rhei 10g, be ground into separately powder, with an amount of Semen Sesami Nigrum oil furnishing paste.

Embodiment two: get Cortex Eucommiae 2g, Rhizoma Coptidis 3g, Radix Platycodonis 15g, Pericarpium Citri Reticulatae 15g, withered trailing plants 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 9g, Radix Et Rhizoma Rhei 5g, be ground into separately powder, with an amount of Semen Sesami Nigrum oil furnishing paste.

Embodiment three: get Cortex Eucommiae 7g, Rhizoma Coptidis 9g, Radix Platycodonis 5g, Pericarpium Citri Reticulatae 5g, withered trailing plants 23g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3g, Radix Et Rhizoma Rhei 15g, be ground into separately powder, with an amount of Semen Sesami Nigrum oil furnishing paste.

Claims

1. Chinese medicine composition for the treatment of chilblain is characterized in that being made by the raw material of Chinese medicine of following weight portion: Cortex Eucommiae 2-7 part, Rhizoma Coptidis 3-9 part, Radix Platycodonis 5-15 part, Pericarpium Citri Reticulatae 5-15 part, withered trailing plants 15-25 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 3-9 part, Radix Et Rhizoma Rhei 5-15 part, Semen Sesami Nigrum oil an amount of.

2. a kind of Chinese medicine composition for the treatment of chilblain according to claim 1 is characterized in that being made by the raw material of Chinese medicine of following weight portion: 5 parts of the Cortexs Eucommiae, 6 parts of Rhizoma Coptidis, 10 parts of Radix Platycodoniss, 10 parts of Pericarpium Citri Reticulataes, 20 parts of withered trailing plants, 6 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 10 parts of Radix Et Rhizoma Rhei, Semen Sesami Nigrum oil an amount of.