CN106390089A - Traditional Chinese medicinal preparation for treating chilblain, and preparation method thereof - Google Patents

Traditional Chinese medicinal preparation for treating chilblain, and preparation method thereof Download PDF

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CN106390089A
CN106390089A CN201611100842.XA CN201611100842A CN106390089A CN 106390089 A CN106390089 A CN 106390089A CN 201611100842 A CN201611100842 A CN 201611100842A CN 106390089 A CN106390089 A CN 106390089A
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李雪灵
李存好
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/235—Foeniculum (fennel)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
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    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The invention is a divisional application of the invention patent application with the application number of 201410156643.5. The invention discloses a traditional Chinese medicinal preparation for treating chilblain, and a preparation method thereof. The traditional Chinese medicinal preparation is mainly prepared from 30-50 g of radix paeoniae rubra, 30-50 g of Ligusticum wallichii, 50-100 g of Crocus sativus, 30-50 g of Salvia miltiorrhiza, 50-100 g of Chinese angelica root, 30-50 g of cassia twig, 30-50 g of Fructus Foeniculi, 50-100 g of Herba Speranskiae Tuberculatae, 30-50 g of camphor, 30-50 g of Radix Astragali, 20-50 g of licorice root, 30-50 g of cinnamon and 30-50 g of ginger. The traditional Chinese medicinal preparation belongs to a pure traditional Chinese medicinal infusion, has high curative effect and no toxic or side effects, can be rapidly absorbed after being smeared on an affected part, allows light frostbite to be cured 1 d later, allows severe frostbite to be cured 3-5 d later, is suitable for clinic large-scale promotion, and has an effective rate of 100% and a cure rate of 98%.

Description

A kind of treat Chinese medicine preparation of chilblain and preparation method thereof
The application is application number 201410156643.5, the applying date is on April 18th, 2014, invention entitled《One kind is controlled Treat Chinese medicine preparation of chilblain and preparation method thereof》Application for a patent for invention divisional application.
Technical field：
The present invention relates to field of medicaments, more particularly to a kind of Chinese medicine preparation treating chilblain.
Background technology：
Chilblain is a kind of obstinate seasonal prevalence disease, and it brings very big misery and the inconvenience of life to many patients. There is no the specific medicament for the treatment of chilblain at present, numerous medicines with regard to treating chilblain all have that effect is poor, cure rate on the market Low, treatment cycle length, the shortcomings of can not thoroughly cure.
Content of the invention：
The curative effect of medication that the purpose of the present invention is aiming at treating at present chilblain is poor, and treatment cycle is long, costly and use The deficiencies such as inconvenience, and provide a kind of Chinese medicine preparation treating chilblain, for achieving the above object, the present invention provide for treating The Chinese medicine preparation of chilblain, is by Radix Paeoniae Rubra, Rhizoma Chuanxiong, Stigma Croci, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Ramulus Cinnamomi, Fructus Foeniculi, Herba speranskiae tuberculatae, Camphora, the Radix Astragali, sweet The formula sealing by a certain percentage of the Chinese medicines such as grass, Cortex Cinnamomi and Rhizoma Zingiberis Recenss was soaked in certain density medical alcohol, through certain time Make after ageing.
The Chinese medicine preparation of the treatment chilblain that the present invention provides has following functions and feature：
1st, this Chinese medicine preparation system pure Chinese medicine preserved material, curative effect is high, have no toxic side effect, and can absorb rapidly, slightly after smearing affected part Cold injury can be fully recovered for 1 day, and severe patient can be cured for 3～5 days, also can prevent cold injury.
2nd, illing skin automatic heating can be made after this Chinese medicine preparation is smeared to reach more than 4 hours.
3rd, this Chinese medicine preparation is used for that small gap has spy because the cold injury red swelling of the skin causing, pain of itching, pimple, black rotten, brothers are big Effect, has dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, dredging the meridian, detumescence relieve the pain the effect of itch.
4th, non-relapse after healing, and leave no trace.
5th, this Chinese medicine preparation also can remove the pigmentation left because of cold injury and other Drug therapy.
The present invention provides the Chinese medicine preparation for the treatment of chilblain, is mainly made up of following medicine materials：30～50 grams of Radix Paeoniae Rubra, river 30～50 grams of rhizome of chuanxiong, 50～100 grams of Stigma Croci, 30～50 grams of Radix Salviae Miltiorrhizae, 50～100 grams of Radix Angelicae Sinensis, 30～50 grams of Ramulus Cinnamomi, Fructus Foeniculi 30～50 Gram, 50～100 grams of Herba speranskiae tuberculatae, 30～50 grams of Camphora, 30～50 grams of the Radix Astragali, 20～50 grams of Radix Glycyrrhizae, 30～50 grams of Cortex Cinnamomi and Rhizoma Zingiberis Recenss 30～50 grams.
The present invention provides the Chinese medicine preparation its preparation method for the treatment of chilblain as follows：
1) weigh each medicine material by formula, be broken into the following powder of 20 mesh with rustless steel pulverizer；
2) by the medicine material powder mix homogeneously in step 1, it is soaked in the glass drying oven filling 5L75% medical alcohol In, deposit ageing 2 weeks in shady place sealing, period is stirred 2 times with Glass rod；
3) filter, leach this ethanol leaching liquid and be Chinese medicine preparation of the present invention.
As needed, said medicine material rate can suitably be adjusted.
Each composition pharmacological action is as described below：
Radix Paeoniae Rubra：Promoting blood circulation and detumescence, has the effect of promoting blood circulation blood stasis expelling；
Rhizoma Chuanxiong：Blood circulation promoting and blood stasis dispelling；Activating QI to alleviate the depression；The effects such as wind-expelling pain-stopping；
Stigma Croci：Promoting blood circulation to remove obstruction in the collateral.Stasis-dispelling and pain-killing is used for because freezing congestion coagulability purpura；
Radix Salviae Miltiorrhizae：Blood circulation promoting and blood stasis dispelling, for stasis of blood stickiness pain；
Radix Angelicae Sinensis：Tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, removing obstruction in the collateral to relieve pain, removes blood stasis, tissue regeneration promoting blood；
Ramulus Cinnamomi：Expelling pathogenic factors from muscles relieving superficies and warmign meridians is promoted blood circulation, and can make cutaneous vasodilation, can promote body temperature；
Fructus Foeniculi：Dispelling cold by warming the meridian, pain relieving, it is used for the positive cold-evil that faints；
Herba speranskiae tuberculatae：Scattered wind damp eliminating, relieve internal heat pain relieving, for rheumatalgia, innominate toxic swelling；
Camphora：Can dehumidify, warming and odynolysis, for the stagnant pain of the scabies itching sore stasis of blood；
The Radix Astragali：Tonifying Qi and lifting yang, inducing diuresis to remove edema, torr sore myogenic；
Radix Glycyrrhizae：Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription, it is usually used in ulcer sores；
Cortex Cinnamomi：Warming the meridian benefit fire, pain relieving inducing diuresis to remove edema, is cold expelling key medicine；
Rhizoma Zingiberis Recenss：Warming spleen and stomach for dispelling cold, can make local blood circulation accelerate, excitor nerve, conscious localized warmth.
Using method：By affected part warm water wash clean, pick this Chinese medicine preparation uniform application 4 times with cotton balls；Smear daily Twice；
Specific embodiment：
With reference to more specifically embodiment, explanation is further spread out to the present invention, it is to be noted that the present invention The Chinese medicine preparation for the treatment of chilblain be not limited to this specific component or form.
Formula one：50 grams of Radix Paeoniae Rubra, 50 grams of Rhizoma Chuanxiong, 50 grams of Stigma Croci, 50 grams of Radix Salviae Miltiorrhizae, 50 grams of Radix Angelicae Sinensis, 50 grams of Ramulus Cinnamomi, Fructus Foeniculi 50 Gram, 50 grams of Herba speranskiae tuberculatae, 50 grams of Camphora, 50 grams of the Radix Astragali, 50 grams of Radix Glycyrrhizae, 50 grams of Cortex Cinnamomi, 50 grams
Formula two：30 grams of Radix Paeoniae Rubra, 30 grams of Rhizoma Chuanxiong, 100 grams of Stigma Croci, 30 grams of Radix Salviae Miltiorrhizae, 70 grams of Radix Angelicae Sinensis, 30 grams of Ramulus Cinnamomi, Fructus Foeniculi 30 grams, 50 grams of Herba speranskiae tuberculatae, 50 grams of Camphora, 50 grams of the Radix Astragali, 20 grams of Radix Glycyrrhizae, 50 grams of Cortex Cinnamomi, 50 grams of Rhizoma Zingiberis Recenss
Formula three：50 grams of Radix Paeoniae Rubra, 50 grams of Rhizoma Chuanxiong, 100 grams of Stigma Croci, 50 grams of Radix Salviae Miltiorrhizae, 80 grams of Radix Angelicae Sinensis, 50 grams of Ramulus Cinnamomi, Fructus Foeniculi 50 grams, 50 grams of Herba speranskiae tuberculatae, 50 grams of Camphora, 50 grams of the Radix Astragali, 50 grams of Radix Glycyrrhizae, 50 grams of Cortex Cinnamomi, 50 grams of Rhizoma Zingiberis Recenss
By the above-mentioned each medicine material weighing by formula, it is broken into the following powder of 20 mesh with rustless steel pulverizer, mixing is all Even, it is soaked in the glass drying oven filling 5L75% medical alcohol, deposit ageing 2 weeks, period Glass rod in shady place sealing Stirring 2 times, then leaches this ethanol leaching liquid and of the present invention Chinese medicine preparation is obtained, patient affected part warm water is cleaned up, uses cotton Ball picks this Chinese medicine preparation uniform application 4 times；Smear daily twice.
Embodiment 1
Patient：Sun, female, 32 years old
Using front symptom：Cold injury in winter both hands within 2013, and swelling phenomenon, have smeared other chilblain medicines several Cream all loses effect, and cold injury tends to serious.
The Chinese medicine preparation produced using above-mentioned formula one, after once, symptom disappears, recovery from illness.
Embodiment 2
Patient：King so-and-so, female, 65 years old
Using front symptom：The serious cold injury of both hands in 2011, every winter, both hands swelling serious it is impossible to stretch song, and with splitting Mouth flowing water, itches pain unbearably, has a strong impact on orthobiosiss, using other ointment Chinese medicine preparation of kind more than ten, all lose effect.
The Chinese medicine preparation produced using above-mentioned formula two, after 3 days, chilblain breach disappears, not red and swollen, does not itch, recovery from illness, Hereafter no recur again.
Embodiment 3
Patient：Lee so-and-so, female, 36 years old
Using front symptom：Both hands cold injury has had more than ten years history, every winter, and both hands swelling is festered, and in many ways seeks medical advice no Really, cold injury is recovered always to leave atropurpureuss scar in defensive position.
The Chinese medicine preparation produced using above-mentioned formula three, is disappeared using both hands swelling after 3 days and forms a scab, after being continuing with 2 days It is discontinued, after hindering crust and coming off, both hands recover normal, no any cold injury vestige, before eliminating, leave cicatrix simultaneously, and more no Recurrence.
From above-mentioned clinical case using effect, Chinese medicine preparation main component of the present invention is natural material, no Toxic and side effects, cure rate is high, and treatment cycle is short, is suitable to clinically large-scale promotion.Show through statistics, with the Chinese medicine of the present invention Preparation is tracked to 2000 chilblain patients treating, and through clinical observation in 3 years, this Chinese medicine preparation effective percentage was 100%, cures Rate reaches 98%.

Claims (5)

1. a kind of Chinese medicine preparation treating chilblain is it is characterised in that be mainly made up of following medicine materials：Radix Paeoniae Rubra 30～50 Gram, 30～50 grams of Rhizoma Chuanxiong, 50～100 grams of Stigma Croci, 30～50 grams of Radix Salviae Miltiorrhizae, 50～100 grams of Radix Angelicae Sinensis, 30～50 grams of Ramulus Cinnamomi, Fructus Foeniculi 30～50 grams, 50～100 grams of Herba speranskiae tuberculatae, 30～50 grams of Camphora, 30～50 grams of the Radix Astragali, 20～50 grams of Radix Glycyrrhizae, 30～50 grams of Cortex Cinnamomi With 30～50 grams of Rhizoma Zingiberis Recenss.
2. treat the Chinese medicine preparation of chilblain according to claim 1 it is characterised in that each medicine material consumption is：Radix Paeoniae Rubra 50 Gram, 50 grams of Rhizoma Chuanxiong, 50 grams of Stigma Croci, 50 grams of Radix Salviae Miltiorrhizae, 50 grams of Radix Angelicae Sinensis, 50 grams of Ramulus Cinnamomi, 50 grams of Fructus Foeniculi, 50 grams of Herba speranskiae tuberculatae, Camphora 50 Gram, 50 grams of the Radix Astragali, 50 grams of Radix Glycyrrhizae, 50 grams of Cortex Cinnamomi and 50 grams of Rhizoma Zingiberis Recenss.
3. treat the Chinese medicine preparation of chilblain according to claim 1 it is characterised in that each medicine material consumption is：Radix Paeoniae Rubra 30 Gram, 30 grams of Rhizoma Chuanxiong, 100 grams of Stigma Croci, 30 grams of Radix Salviae Miltiorrhizae, 70 grams of Radix Angelicae Sinensis, 30 grams of Ramulus Cinnamomi, 30 grams of Fructus Foeniculi, 50 grams of Herba speranskiae tuberculatae, Camphora 50 Gram, 50 grams of the Radix Astragali, 20 grams of Radix Glycyrrhizae, 50 grams of Cortex Cinnamomi and 50 grams of Rhizoma Zingiberis Recenss.
4. treat the Chinese medicine preparation of chilblain according to claim 1 it is characterised in that each medicine material consumption is：Radix Paeoniae Rubra 50 Gram, 50 grams of Rhizoma Chuanxiong, 100 grams of Stigma Croci, 50 grams of Radix Salviae Miltiorrhizae, 80 grams of Radix Angelicae Sinensis, 50 grams of Ramulus Cinnamomi, 50 grams of Fructus Foeniculi, 50 grams of Herba speranskiae tuberculatae, Camphora 50 Gram, 50 grams of the Radix Astragali, 50 grams of Radix Glycyrrhizae, 50 grams of Cortex Cinnamomi and 50 grams of Rhizoma Zingiberis Recenss.
5. according to claim 1, the preparation method of Chinese medicine preparation described in 2,3 or 4, comprise the following steps：
1) weigh each medicine material by formula, be broken into the following powder of 20 mesh with rustless steel pulverizer；
2) by the medicine material powder mix homogeneously in step 1, it is soaked in the glass drying oven filling 5L75% medical alcohol, in Ageing 2 weeks is deposited in shady place sealing, and period is stirred 2 times with Glass rod；
3) filter, leach this ethanol leaching liquid and be Chinese medicine preparation of the present invention.
CN201611100842.XA 2014-04-18 2014-04-18 Traditional Chinese medicinal preparation for treating chilblain, and preparation method thereof Pending CN106390089A (en)

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CN104524393A (en) * 2014-11-29 2015-04-22 王桂芝 Chinese medicinal preparation for treatment of recurrent chilblain
CN104548010A (en) * 2014-12-29 2015-04-29 西宁意格知识产权咨询服务有限公司 Traditional Chinese medicine composition for treating chilblain
CN104547180A (en) * 2014-12-29 2015-04-29 西宁意格知识产权咨询服务有限公司 Cream for treating chilblain and preparation method for cream
CN104740565A (en) * 2015-03-22 2015-07-01 张晓利 Traditional Chinese medicine composition for treating cold injury
CN106692918A (en) * 2016-12-05 2017-05-24 李存好 Traditional Chinese medicine preparation for treating chilblains and preparation method of traditional Chinese medicine preparation

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CN1839984A (en) * 2006-01-05 2006-10-04 袁安龙 Externally applied Chinese medicinal aqueous formulation for treating kibe

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