CN102091229A - Traditional Chinese medicine for treating diabetic coronary heart disease - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating diabetic coronary heart disease, belonging to the field of traditional Chinese medicines for treating diabetes. The traditional Chinese medicine is prepared from fragrant solomonseal rhizome, Chinese angelica, radix pseudo-ginseng, radix cynanchi atrati, lucid ganoderma, salvia miltiorrhiza bunge and other raw materials. The traditional Chinese medicine has the effects of supporting health energy, invigorating qi, nourishing blood, nourishing yin, clearing away heat, promoting blood circulation and dispersing blood stasis, and has the advantages of distinct effect, definite drug effect and quick action.

Description

A kind of Chinese medicine for the treatment of diabetic coronary heart disease

Technical field

The invention belongs to the field of Chinese medicines of treatment diabetes.

Background technology

Diabetic coronary heart disease is meant the coronary heart disease that diabetics is concurrent, is due to the cardiovascular injuries pathological changes and neuropathy that is taken place on the basis of metabolism disorders such as sugar, fat.Being the diabetes most common complication, also is the main cause of death of diabetics.According to statistics, diabetics 70% is died from diabetic coronary heart disease.The present Chinese medicine aspect that is intended to treat diabetic coronary heart disease, the deficiency of two aspects of existence: the one, effect is obvious inadequately, and the 2nd, it is slower to take effect.So that many diabetic coronary heart disease patients stand the torment of feeling of oppression and pain in the chest, cardiopalmus agitation for a long time owing to can not get the treatment of active drug, face the danger of myocardial infarction, patient and family members thereof are dissatisfied to this.

At problem set forth above, the invention provides a kind of Chinese medicine for the treatment of diabetic coronary heart disease, it can solve, and this type of Chinese medicine effect was obvious inadequately in the past, the slower problem that takes effect, effective, instant effect, it is remarkable to have effect, drug effect is definite, the advantage of quick result.

Summary of the invention

The present invention is achieved through the following technical solutions:

1, a kind of Chinese medicine for the treatment of diabetic coronary heart disease adopts the raw material of Chinese medicine preparation, and filling a prescription is (by weight):

Rhizoma Polygonati Odorati 5-15 part Radix Angelicae Sinensis 6-18 part Radix Notoginseng 3-9 part

Radix Cynanchi Atrati 5-15 part Ganoderma 6-18 part Radix Salviae Miltiorrhizae 6-18 part

The Chinese medicine of this treatment diabetic coronary heart disease is made by following method:

(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is as follows: Ganoderma is broken into graininess, cross 40 mesh sieves →, concentrate → mixed, leave standstill 10-12 hour, centrifugal → as to add 75% ethanol with 95% ethanol of 3 times of volumes with 1: 20 hot water (95 ℃) lixiviate → lixiviating solution decompression, precipitate polysaccharide → dry the ganoderan extract fine powder;

(2) by above-mentioned weight ratio, Rhizoma Polygonati Odorati, Radix Angelicae Sinensis, Radix Cynanchi Atrati, Radix Salviae Miltiorrhizae are extracted through conventional water extraction process, make extract extractum fine powder;

(3) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, make Chinese medicine granules, capsule, tablet with above-mentioned (1), (2) two kinds of extract fine powders.

The present invention is according to the folk tradition prescription, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling develops meticulously.We think in research, the general hypoimmunity of diabetics, and this disease is many by diabetes with the passing of time, scorching yin-damaging and Qi consuming, deficiency of both QI and YIN is due to the heart arteries and veins stasis of blood hinders.Morbific all multifactor in, hypoimmunity is the very corn of a subject and key.So the present invention attaches most importance to enhancing immunity, benefiting QI and nourishing blood, replenishing YIN and removing heat, blood circulation promoting and blood stasis dispelling is obtained good efficacy.At present, the Western medicine and the Chinese medicine of multiple treatment heart disease, coronary heart disease being arranged on the China market---the advantage of nitroglycerin, SUXIAO JIUXIN WAN is emergency when chest pain unexpected generation uncomfortable in chest, allows the patient avoid myocardial infarction; The advantage of Isosorbide fat sheet, Radix Salviae Miltiorrhizae drop pill is in 8～12 hours time, control chest pain slight generation uncomfortable in chest or not generation; And the advantage of Chinese medicine of the present invention is fundamentally to improve blood supply of cardiac muscle, allow chest pain uncomfortable in chest be not within 12 hours but in the long time, gradually reduce, alleviate, until not taking place.We can say that the present invention compares with above-mentioned four kinds of above the ordinary Chinese medicine and western medicine, the former stresses to control " mark ", and this medicine stresses to control " basis ", is each have their own advantage, each have their own purposes.Thus, this patient is many a kind of better optimize therapeutic scheme---" 1+1+1 ", promptly uses nitroglycerin (SUXIAO JIUXIN WAN) " emergency "; Do not show effect in 12 hours with Isosorbide fat sheet (Radix Salviae Miltiorrhizae drop pill) control; Reduce chest pain generation uncomfortable in chest with the present invention.Value of the present invention that Here it is.Ganoderma, Radix Angelicae Sinensis the body resistance strengthening and constitution consolidating among the we, benefiting QI and nourishing blood, tranquilizing by nourishing the heart, enhancing human body immunity power, " removing " effect of immunity makes blood clean, and is no longer sticky, but rich mobile, this is the basis of improving blood supply of cardiac muscle; Radix Salviae Miltiorrhizae, pseudo-ginseng blood-circulation-invigovating are promoted blood circulation, blood-activating analgetic, and Ganoderma, Radix Angelicae Sinensis and Radix Salviae Miltiorrhizae, Radix Notoginseng are share, the prosperous hemapodium of gas, tissue regeneration promoting blood and blood stasis removing blood, " reparation " effect of immunity, softening arteria coronaria blood vessel reduces stasis of blood resistance, makes blood supply of cardiac muscle full; Be aided with the Rhizoma Polygonati Odorati nourishing YIN to relieve dryness, heart tonifying and coronary artery dilating effect are arranged; The Radix Cynanchi Atrati heat clearing away, diuresis, the moon that nourishes heart is grown conception vessel.All medicine compatibilities bring out the best in each other, and play the body resistance strengthening and constitution consolidating altogether, benefiting QI and nourishing blood, replenishing YIN and removing heat, the merit of blood circulation promoting and blood stasis dispelling.Make a general survey of full side, the merit of existing element culturing fixed folder does not have the numbness that consumes impairment of QI the moon again, and residence is mended in logical, the good recipe that nourishes heart really and promote blood circulation.Effective, instant effect, it is remarkable to have effect, and drug effect is definite, the advantage of quick result.

The specific embodiment

By following embodiment the present invention is done and to specify:

1, get following prescription (weight is unit by gram):

Rhizoma Polygonati Odorati 60 gram Radix Angelicae Sinensis 70 gram Radix Notoginseng 30 grams

Radix Cynanchi Atrati 60 kairine sesames 70 gram Radix Salviae Miltiorrhizaes 70 grams

Weight is extracted Ganoderma with decoction and alcohol sedimentation technique in accordance with regulations; With conventional water extraction process Rhizoma Polygonati Odorati, Radix Angelicae Sinensis, Radix Cynanchi Atrati, Radix Salviae Miltiorrhizae are extracted, make extract fine powder 66 grams altogether, Radix Notoginseng is ground into fine powder, mix with said extracted thing fine powder, stir, make fine particle, the capsule of packing into No. 0, make 342 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

2, get following prescription (weight is unit by gram):

Rhizoma Polygonati Odorati 100 gram Radix Angelicae Sinensis 130 gram Radix Notoginseng 60 grams

Radix Cynanchi Atrati 100 kairine sesames 130 gram Radix Salviae Miltiorrhizaes 130 grams

By above-mentioned same method, make 635 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

3, get following prescription (weight is unit by gram):

Rhizoma Polygonati Odorati 150 gram Radix Angelicae Sinensis 180 gram Radix Notoginseng 80 grams

Radix Cynanchi Atrati 150 kairine sesames 180 gram Radix Salviae Miltiorrhizaes 180 grams

By above-mentioned same method, make 885 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

4, get following prescription (by weight):

3 parts of 6 portions of Radix Notoginseng of 5 parts of Radix Angelicae Sinensis of Rhizoma Polygonati Odorati

6 parts of 6 parts of Radix Salviae Miltiorrhizaes of 5 portions of Ganodermas of Radix Cynanchi Atrati

By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

5, get following prescription (by weight):

7 parts of 15 portions of Radix Notoginseng of 12 parts of Radix Angelicae Sinensis of Rhizoma Polygonati Odorati

15 parts of 15 parts of Radix Salviae Miltiorrhizaes of 12 portions of Ganodermas of Radix Cynanchi Atrati

By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

Clinical data:

The present invention is an example with traditional Chinese medical science diabetic coronary heart disease, through 7 routine clinical observations.Selecting the tcm diagnosis diabetic coronary heart disease is standard: diabetics has the inclination to distinguish malaise symptoms in work, excited, heavy meal or when catching cold the back---cardiopalmus agitation, limb soft weak, chest pain is uncomfortable in chest, dyspnea, have a rest or take nitroglycerin after alleviate.As above symptom can be made a definite diagnosis.In making a definite diagnosis the object of observation, male's 3 examples, women's 4 examples do not have other serious disease, and the age is 47 years old-81 years old, 63.7 years old mean age.

Efficacy determination:

1, produce effects: diabetics is equal under the batten spare cardiac distress symptom and obviously alleviates in work, excited, heavy meal or after catching cold---and the cardiopalmus agitation alleviates, and tachycardia disappears, pulse 60～90 times/minute; The soft weak alleviation of limb, on one's body energetically; Chest pain obvious improvement uncomfortable in chest, attack times reduces, and degree alleviates; Breathe smooth and easyly, heart district is comfortable; The visible blood supply of cardiac muscle of electrocardiogram improves.

2, effective: cardiac distresses such as cardiopalmus agitation, chest pain are uncomfortable in chest, dyspnea are alleviated to some extent.

3, invalid: the disease no change.

During clinical experiment, except that the antidiabetic drug that diabetics is necessary is taken (medicine is constant, amount is constant) as usual, withdraw other medicines and health nutrient.Taking Chinese medicinal capsule of the present invention, observed 6 months, is a course of treatment.Instructions of taking: every day 2 times, each 3 capsules, every capsules include Chinese medicine fine powder and extract 0.28 gram, warm water delivery service after meal, symptom promptly has alleviation after 1 month, take 6 months after, symptom is obviously improved.7 philtrums of clinical experiment, produce effects 3 people, effective 3 people, invalid 1 people, total effective rate 85.7%.

Claims (1)

1. Chinese medicine for the treatment of diabetic coronary heart disease, it is characterized in that: it is to make with the component of following weight ratio: Rhizoma Polygonati Odorati 5-15 part, Radix Angelicae Sinensis 6-18 part, Radix Notoginseng 3-9 part, Radix Cynanchi Atrati 5-15 part, Ganoderma 6-18 part, Radix Salviae Miltiorrhizae 6-18 part.