CN102091200A - Chinese medicinal preparation with effects of promoting blood circulation by removing blood stasis and coaptating bone and ligament - Google Patents
Chinese medicinal preparation with effects of promoting blood circulation by removing blood stasis and coaptating bone and ligament Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal preparation with the effects of promoting blood circulation by removing blood stasis and coaptating bones and ligaments. The Chinese medicinal preparation is a capsule prepared from the following Chinese medicinal herbs in parts by weight: 10-15 parts of pseudo-ginseng, 10-15 parts of drynaria rhizome, 10-15 parts of dogwood, 10-20 parts of root of red-rooted salvia, 5-15 parts of dragon's blood, 10-15 parts of safflowers, 5-15 parts of ground beetles, 10-20 parts of radix astragali, 10-20 parts of radix codonopsitis, 10-15 parts of angelica sinensis, 10-20 parts of prepared rehmannia roots, 10-20 parts of himalayan teasel root and 5-10 parts of native copper. The pseudo-ginseng for promoting blood circulation by removing blood stasis and relieving pains and the himalayan teasel root for tonifying liver and kidney and coaptating the ligaments and bones are taken as monarch medicines; and modern pharmacological researches prove that the himalayan teasel root has the effect of assisting tissue regeneration and has obvious effect on repairing a bone broken end. The angelica sinensis can promote the blood circulation and enrich the blood, and contains an effective component of ferulic acid which can improve microcirculation and dilate blood vessels, the dogwoods nourish liver and kidney and replenish essence and blood, the ground beetles promote the blood circulation by removing the blood stasis and coaptate the ligaments and bones, and the three Chinese medicinal herbs are ministerial medicines. The root of red-rooted salvia is bitter and cool in nature, promotes the blood circulation, cools and nourishes the blood and has functions similar to that of four substances, the radix astragali is sweet and slightly moderate in nature, tonifies qi and nourishes the blood, the native copper dissipates the stasis, relieves the pains and coaptates the bones and ligaments, and the three Chinese medicinal herbs are adjuvant medicines.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and production technology thereof that blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged.
Background technology
Fracture is modal orthopaedic disease.Although treatment means is brought in constant renewal in, treatment level also improves constantly, and the incidence rate of nonunion is still up to 8%～10%.Nonunion can cause ankylosis, and limb shortening and afunction are brought very big misery to the patient, and operating difficulty is big once more, complication many and recovery time is long, and surgical effect is also undesirable.
Nonunion does not still have the definition of generally acknowledging so far, the classification of fracture difference, and healing time is also different.It is generally acknowledged; it is delayed union that union of fracture surpasses normal healing required time; and fractured back 6～8 months; fracture end still has pain and abnormal movement; X-ray film shows that broken ends of fractured bone callus is few or does not have callus formation, broken ends of fractured bone sclerosis, atrophy, pulp cavity sealing; obvious gap is arranged between the broken ends of fractured bone, observe continuously through 3 months that still not to have healing sign person diagnosable be nonunion.On iconography, nonunion is divided into loose type, no callus type and atrophic type, the former mainly with fracture site between unstable relevant, the back both transport not good relevant with fracture end blood.Cause the reason of nonunion a lot, comprise local factor and systemic factor.Sex, age, nutrition of whole body situation and whether smoking etc. all union of fracture is had in various degree influence.Local factor such as high-energy damage, large tracts of land soft tissue defects around the fracture, and bony defect or infection, radiotherapy, the not good grade of the local blood fortune of fracturing all can cause nonunion.Iatrogenic factors also is a key factor.
Therefore, seek the reason of nonunion, reduce its incidence rate, improve cure rate; It is the common problem of paying close attention to of orthopaedics always.
Medicine curative effect of the prior art is also not fully up to expectations.Seek the better medicine of therapeutic effect and listed the agenda of orthopaedics in.
Summary of the invention:
The application's goal of the invention aims to provide a kind of Chinese medicine preparation and preparation method that blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged.
Another object of the present invention provides the application of above-mentioned Chinese medicine preparation in preparation treatment kainogenesis fracture or old fracture medicine.
The application's technical scheme is:
Develop a kind of Chinese medicine preparation that blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged, it is characterized in that the capsule of making by the Chinese crude drug of following weight ratio:
10～15 parts of Radix Notoginseng, 10～15 parts of Rhizoma Drynariae, 10～15 parts of Fructus Corni, 10～20 parts of Radix Salviae Miltiorrhizaes, 5～15 parts of Sanguis Draxonis, 10～15 parts on Flos Carthami, 5～15 parts of Eupolyphaga Seu Steleophagas, 10～20 parts of the Radixs Astragali, 10～20 parts of Radix Codonopsis, 10～15 parts of Radix Angelicae Sinensis, 10～20 parts of Radix Rehmanniae Preparata, 10～20 parts of Radix Dipsacis, 5～10 parts of Pyritums.
Above-mentioned a kind of Chinese medicine preparation that blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged is characterized in that the capsule of being made by the Chinese crude drug of following weight ratio:
12～15 parts of Radix Notoginseng, 12～15 parts of Rhizoma Drynariae, 12～15 parts of Fructus Corni, 17～20 parts of Radix Salviae Miltiorrhizaes, 12～15 parts of Sanguis Draxonis, 12～15 parts on Flos Carthami, 12～15 parts of Eupolyphaga Seu Steleophagas, 17～20 parts of the Radixs Astragali, 17～20 parts of Radix Codonopsis, 12～15 parts of Radix Angelicae Sinensis, 17～20 parts of Radix Rehmanniae Preparata, 17～20 parts of Radix Dipsacis, 8～10 parts of Pyritums.
Above-mentioned a kind of Chinese medicine preparation that blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged is characterized in that the capsule of being made by the Chinese crude drug of following weight ratio:
10～13 parts of Radix Notoginseng, 10～13 parts of Rhizoma Drynariae, 10～13 parts of Fructus Corni, 10～15 parts of Radix Salviae Miltiorrhizaes, 5～10 parts of Sanguis Draxonis, 10～13 parts on Flos Carthami, 5～10 parts of Eupolyphaga Seu Steleophagas, 10～15 parts of the Radixs Astragali, 10～15 parts of Radix Codonopsis, 10～13 parts of Radix Angelicae Sinensis, 10～15 parts of Radix Rehmanniae Preparata, 10～15 parts of Radix Dipsacis, 5～8 parts of Pyritums.
Above-mentioned a kind of preparation method that the Chinese medicine preparation of blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged, it is characterized in that each medical material make only in accordance with regulations, concoct the back:
(1) take by weighing each medical material by dosage, pulverize separately is to particle diameter 100～150 μ m fine powders, and is standby;
(2) each medical material fine powder of dosage mixes, and stirs evenly, and crosses 120 mesh sieves, and is standby;
(3) with 60 ℃ of oven dry of the medical material fine powder behind the mixing 1 hour, standby;
(4) with the medical material fine powder of oven dry, use ultraviolet radiation sterilization 2 hours, standby;
(5) the medical material fine powder after will sterilizing incapsulates in accordance with regulations; Stipulate down to be up to the standards by pharmacopeia capsule item, promptly get the Chinese medicinal capsule finished product of blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, replenishing QI and blood, reunion of bone.
Above-mentioned a kind of Chinese medicine preparation that blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged, the application in preparation treatment kainogenesis fracture or old fracture medicine.
The advantage of the technical program:
Pure Chinese medicinal preparation, function liver and kidney tonifying, blood circulation promoting and blood stasis dispelling, the cold-damp of dispeling the wind.Curative effect is obvious, onset is rapid and lasting; Do not find obvious toxic and side effects, medication is convenient; Medical material is inexpensive, be easy to get, and common people afford to use, and are fit to national conditions.
Efficacy analysis
The traditional Chinese medical science thinks and cures the disease earlier eliminating evilly that strengthening the body resistance recovers healthy energy, with just eliminating evil, and the recovery capability of enhancing body self.
Fracture is to have been destroyed the integrity and the seriality of bone by direct violence or indirect violence.The notion of fracture, ancients are familiar with very early to some extent, names of disease such as existing " disease bone ", " disease shin ", " disease elbow " in the inscriptions on bones or tortoise shells, " all gift heavenly officials " have put down in writing " fracture complicated with infection ", " the Ling Shu Miraculous Pivot or Divine Axis pathogen is hidden the sick shape in mansion " put down in writing " severe lumbago ", and this name of disease of fracturing comes from Tang Wangtao " medical secrets of official ".Old fracture is divided into: delayed union of fracture and nonunion.The agglutination of fracture is the process of " stasis of blood goes, newborn, bone close ", and whole process is continue progressive, generally can be divided into organization of hematoma phase, primary callus phase and callus and transform the phase.Under the normal condition, fracture can heal after reduction is fixing voluntarily.But under some factor affecting, delayed union of fracture or nonunion take place.The factor that influences union of fracture has: (1) age children's life is flourishing, blastoprolepsis, and the regeneration of tissue and plasticity ability are strong, and healing rate is fast, and old people then QI and blood is weak, and caused by liver and kidney deficiency is so it is slow to grow the speed of skeleton after the fracture.(2) body constitution: in vigorous health, then QI and blood is vigorous, and it is warm that muscles and bones is able to QI and blood, and healing rate is fast, plain body weakness, and deficiency of the liver and kindey, deficiency of qi and blood, healing rate is slow.(3) contact of section: the contact of section is big more, and it is fast more to heal, otherwise, then slow.(4) blood of fracture segment supplies situation: two kinds of situations are arranged, and one, after the fracture, the angiolysis of fracture segment is more serious, insufficiency of vital energy and blood, healing rate is slow.Its two, the blood of fracture segment own is for bad, fracture in addition, damage blood vessels, influence healing.As neck of femur, following 1/3 section of tibia, lunar and nut bone etc." element is asked the regulating menstruation opinion " points out " people's the owner, blood and gas ear.", " the passages through which vital energy circulates person, so promoting the circulation of blood arteries and veins and seek negative and positive moistens muscles and bones, sharp joint person also." point out in " the roman class is wanted preface " " and limbs decrease in outside, then QI and blood is hindered in interior, battalion defends does not to some extent pass through, internal organs by discord." liver governing tendons ", " kidney governing bones ", blood stored in the liver master muscle, liver blood is full, muscle get support, deficiency of liver-blood, the function of muscle will take place unusually.Kidney storing essence, the smart marrow of giving birth to, marrow nourishing bone is so the growth of bone, growth, reparation must rely on the nourishing and the promotion of kidney vital essence.Deficiency of kidney-essence, bone marrow lose supports, the healing of influence fracture.Sun Simiao has been enumerated kind surplus the medicine 50 of mending bone marrow, hard muscles and bones, longue meat in supplement to Thousand Golden Prescriptions, these medicines have the effect of invigorating the liver and kidney, strengthening the spleen and stomach and QI invigorating and blood producing mostly.Propose to promote bone marrow, muscle growth to repair this point from him with invigorating the liver and kidney, strengthening the spleen and stomach medicine, can illustrate, he has recognized that: the growth reparation and the movable function of bone, muscle and muscle, must pass through adjusting and reinforcing liver and kidney, thereby tonification bone marrow, by harmonizing the spleen and stomach, vital energy regualting and blood circulation-promoting and invigorating QI and blood just can reach.Its kidney invigorating is supported marrow and is repaired theory with short osteogenesis, becomes the basis of orthopedics department physiological and pathological later age.The old scholar of the Qing Dynasty selects at " the dialectical record of all kinds of diseases and ailments " medium cloud: " blood not reviver's stasis of blood does not go, and the stasis of blood does not go person's bone not connect yet." still treat nonunion and adopt Drug Capsule among blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, replenishing QI and blood, the reunion of bone, and obtain promising result.
During the technical solution of the present invention medicine was formed, with the Radix Notoginseng of promoting blood circulation, removing blood stasis and relieving pain, the Radix Dipsaci of invigorating the liver and kidney, reuniting the fractured tendons and bones was a monarch drug.Modern pharmacology research Radix Dipsaci helps the effect of tissue regeneration, and the reparation of fracture site is had obvious effect.Radix Angelicae Sinensis can be invigorated blood circulation, and can enrich blood its contained effective ingredient ferulic acid energy microcirculation improvement, blood vessel dilating again.Fructus Corni nourishing the liver and kidney, replenishing essence blood, Eupolyphaga Seu Steleophaga blood circulation promoting and blood stasis dispelling, reunion of fractured tendons and bones are ministerial drug altogether.The Radix Salviae Miltiorrhizae bitter in the mouth, cool in nature.Invigorate blood circulation, removing heat from blood nourishes blood, merit is with four things.Radix Astragali sweet in the mouth, slightly warm in nature, QI invigorating and blood producing.Pyritum eliminating stasis to stop pain, reunion of bone are adjuvant drug altogether.All medicines are played the merit of blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, replenishing QI and blood, reunion of bone altogether.
In the clinic trial, once carried out clinical verification, other related drugs of stopping using during the treatment with " Sun Shi blood circulation promoting and blood stasis dispelling capsule " title " hospital is cured in precious Central China ", oral Chinese medicine preparation, every day three times, consumption once is equivalent to the former powder 4.5g of medical material, is equivalent to the former powder 13.5g of medical material every day; One month is a course of treatment; Curative effect: generally take preparation of the present invention and get final product produce effects 1～2 course of treatment; Get final product clinical recovery 3～4 courses of treatment.
Curative effect determinate standard is:
Clinical cure: the subjective symptoms sign disappears, the training check result continuous 3 times in range of normal value, and can consolidate;
Produce effects: the subjective symptoms sign is most of to disappear, and the training check result is clearly better, basic normal or approaching normal:
Effectively: the subjective symptoms sign is obviously improved, and the training check result takes a turn for the better to some extent:
Invalid: symptom and sign and training check that numerical value does not have improvement substantially before and after the treatment.
Carry out between clinical probation effective percentage 100% in hospital; Obvious effective rate 95%; Clinical cure rate is greater than 90%.Meaning with further further investigation and popularization.
Model case:
1, Lee so-and-so, man, 32 years old, first visit on March 27 in 2005.Right shoulder wheel is hindered stiff 5 hours.Training is checked: the local swelling of right shoulder, and the inboard visible ecchymosis of upper arm, pain, tenderness, dysfunction, the inside protrusions angulation deformity can be touched bony crepitus and abnormal movement forward.Film making is shown: the right side fracture of the surgical neek of the humerus.Give manual reduction, the plintlet external fixation.Film making check para-position is good to line.Give Chinese medicinal capsule, every 0.45g, each 4.5g, every day three times, half an hour, warm water took after meal, took 10 days, and the further consultation film making: para-position is good to line, and fracture site is callus formation in a small amount.Continue and obeyed 15 days, film making is shown: measure callus formation in the fracture site, broken ends of fractured bone healing.Remove clamping plate, advise the patient to do the shoulder joint activity, and drug withdrawal.Follow up a case by regular visits to after 10 days, right shoulder activity is fully recovered freely.
2, Chen, woman, 65 years old, first visit on April 5 in 2005.Left side wrist is got injured by a fall swelling, stiff 3 hours.Training is checked: swelling around the left carpal joint, and pain, left forearm lower end deformity, tenderness is obvious, bracket movable function obstacle.Support or oppose side displacement of far-end, the forearm lower end is " table fork sample " deformity, the wrist dorsal part far-end apophysis of can laying one's hand on and fracture.Film making is shown: colles' fracture.Give manual reduction, the plintlet external fixation.Film making check para-position is good to line.Give Chinese medicinal capsule, every 0.45g, each 4.5g, every day three times, half an hour, warm water took after meal, took 10 days, and the further consultation film making: para-position is good to line, and fracture site is callus formation in a small amount.Continue and obeyed 20 days, film making is shown: broken ends of fractured bone healing.Remove clamping plate, advise the patient to do the carpal joint activity, and drug withdrawal.Follow up a case by regular visits to after 10 days, left wrist activity is fully recovered freely.
3, Zhang, man, 42 years old, left fracture of talus postoperative 7 months.The patient got injured by a fall left ankle before July, film making is shown: left fracture of talus.At city institute line-spacing bone internal fixation of fracture.Film making is shown before 10 days: fracture site does not have callus formation, border sclerosis.JIUYUE came me institute to go to a doctor on the 10th in 2005.Be diagnosed as left fracture of talus disunion.Give Chinese medicinal capsule, every 0.45g, each 4.5g, every day three times, half an hour, warm water took after meal, took 2 months, and the further consultation film making: fracture site is callus formation in a small amount.Continue and obeyed 2 months, film making is shown: a large amount of callus formation are arranged, broken ends of fractured bone healing.Drug withdrawal.Follow up a case by regular visits to after after half a year, removed internal fixation, recovery from illness.
4,, Dong so-and-so, man, 25 years old, right fracture of tibia postoperative 12 months.Patient's December cause traffic accident right leg of wounding, film making is shown: the left tibia comminuted fracture.At certain institute's row fracture of tibia internal fixation with steel plate.Before August, the patient falls down accidentally, the steel plate fracture, and capable again draw point internal fixation, film making is shown before March: fracture site does not have callus formation.Through treating 2 months with bone peptide injection, the commentaries on classics of not getting better of making film comes my institute to go to a doctor on March 5th, 2006.Be diagnosed as the left tibia nonunion.Give Chinese medicinal capsule, every 0.45g, each 4.5g, every day three times, half an hour, warm water took after meal, took 3 months, and the further consultation film making: fracture site is callus formation in a small amount.Continue and obeyed 2 months, broken ends of fractured bone healing is shown in film making.Drug withdrawal.Follow up a case by regular visits to after after 1 year, removed internal fixation, recovery from illness.
5, grandson so-and-so, the woman, 36 years old, pelvis was wounded, stiff 6 hours, on May 5th, 2005 income institute.The patient before 5 hours by the motorcycle pelvis of wounding, stiff, the training inspection: local swelling, pain, dysfunction has ecchymosis, defecation is unobstructed.The pelvic compression and separation test positive.Left ulnar fracture is shown in film making, and para-position can.Give Chinese medicinal capsule, every 0.45g, each 4.5g, every day three times, half an hour, warm water took after meal, advised and lay up, and took 20 days, and the further consultation film making: para-position is good to line, and fracture site is callus formation in a small amount.Continue and obeyed 20 days, film making is shown: broken ends of fractured bone healing.Advise the patient movable down, and drug withdrawal.Follow up a case by regular visits to after January, activity is fully recovered freely.
The specific embodiment:
Below in conjunction with embodiment invention is further elaborated.
Embodiment 1
Dosage:
Radix Notoginseng 15g, Rhizoma Drynariae 15g, Fructus Corni 15g, Radix Salviae Miltiorrhizae 20g, Sanguis Draxonis 15g, Flos Carthami 15g, Eupolyphaga Seu Steleophaga 15g, Radix Astragali 20g, Radix Codonopsis 20g, Radix Angelicae Sinensis 15g, Radix Rehmanniae Preparata 20g, Radix Dipsaci 20g, Pyritum 10g.
All medical materials are pharmacopeia and record medical material.
Preparation method is that the back is made, concocted to each medical material in accordance with regulations only:
(1) take by weighing each medical material by dosage, pulverize separately is to particle diameter 100～150 μ m fine powders, and is standby;
(2) each medical material fine powder of dosage mixes, and stirs evenly, and crosses 120 mesh sieves, and is standby;
(3) with 60 ℃ of oven dry of the medical material fine powder behind the mixing 1 hour, standby;
(4) with the medical material fine powder of oven dry, use ultraviolet radiation sterilization 2 hours, standby;
(5) the medical material fine powder after will sterilizing incapsulates in accordance with regulations; Stipulate down to be up to the standards by pharmacopeia capsule item, promptly get the Chinese medicinal capsule finished product of blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, replenishing QI and blood, reunion of bone.Make 1000 of capsules, every heavy 0.45g.
Application in this Chinese medicinal capsule preparation treatment kainogenesis fracture or the old fracture medicine, (once using trade name " Sun Shi bone-knitting capsule ") also obtains promising result.
Embodiment 2
Dosage: Radix Notoginseng 10g, Rhizoma Drynariae 10g, Fructus Corni 10g, Radix Salviae Miltiorrhizae 10g, Sanguis Draxonis 5g, Flos Carthami 10g, Eupolyphaga Seu Steleophaga 5g, Radix Astragali 10g, Radix Codonopsis 10g, Radix Angelicae Sinensis 10g, Radix Rehmanniae Preparata 10g, Radix Dipsaci 10g, Pyritum 5g.
All the other are with embodiment 1
Embodiment 3
Dosage: Radix Notoginseng 12g, Rhizoma Drynariae 12g, Fructus Corni 12g, Radix Salviae Miltiorrhizae 12g, Sanguis Draxonis 10g, Flos Carthami 12g, Eupolyphaga Seu Steleophaga 10g, Radix Astragali 12g, Radix Codonopsis 12g, Radix Angelicae Sinensis 12g, Radix Rehmanniae Preparata 12g, Radix Dipsaci 12g, Pyritum 10g.
All the other are with embodiment 1
Embodiment 4
Dosage: Radix Notoginseng 13g, Rhizoma Drynariae 13g, Fructus Corni 13g, Radix Salviae Miltiorrhizae 13g, Sanguis Draxonis 8g, Flos Carthami 13g, Eupolyphaga Seu Steleophaga 8g, Radix Astragali 13g, Radix Codonopsis 13g, Radix Angelicae Sinensis 13g, Radix Rehmanniae Preparata 13g, Radix Dipsaci 13g, Pyritum 8g.
All the other are with embodiment 1
Embodiment 5
Dosage: Radix Notoginseng 20g, Rhizoma Drynariae 15g, Fructus Corni 12g, Radix Salviae Miltiorrhizae 15g, Sanguis Draxonis 10g, Flos Carthami 15g, Eupolyphaga Seu Steleophaga 15g, Radix Astragali 15g, Radix Codonopsis 12g, Radix Angelicae Sinensis 12g, Radix Rehmanniae Preparata 12g, Radix Dipsaci 20g, Pyritum 10g.
All the other are with embodiment 1
Embodiment 6
Dosage: Radix Notoginseng 20g, Rhizoma Drynariae 10g, Fructus Corni 10g, Radix Salviae Miltiorrhizae 15g, Sanguis Draxonis 5g, Flos Carthami 15g, Eupolyphaga Seu Steleophaga 5g, Radix Astragali 15g, Radix Codonopsis 15g, Radix Angelicae Sinensis 10g, Radix Rehmanniae Preparata 10g, Radix Dipsaci 15g, Pyritum 5g.
All the other are with embodiment 1
Embodiment 7
Dosage: Radix Notoginseng 15g, Rhizoma Drynariae 13g, Fructus Corni 13g, Radix Salviae Miltiorrhizae 13g, Sanguis Draxonis 15g, Flos Carthami 12g, Eupolyphaga Seu Steleophaga 15g, Radix Astragali 12g, Radix Codonopsis 12g, Radix Angelicae Sinensis 12g, Radix Rehmanniae Preparata 12g, Radix Dipsaci 20g, Pyritum 10g.
All the other are with embodiment 1
Embodiment 8
Dosage: Radix Notoginseng 20g, Rhizoma Drynariae 10g, Fructus Corni 10g, Radix Salviae Miltiorrhizae 10g, Sanguis Draxonis 10g, Flos Carthami 10g, Eupolyphaga Seu Steleophaga 15g, Radix Astragali 15g, Radix Codonopsis 15g, Radix Angelicae Sinensis 15g, Radix Rehmanniae Preparata 15g, Radix Dipsaci 15g, Pyritum 5g.
All the other are with embodiment 1
Embodiment 9
Dosage: Radix Notoginseng 20g, Rhizoma Drynariae 15g, Fructus Corni 15g, Radix Salviae Miltiorrhizae 15g, Sanguis Draxonis 5g, Flos Carthami 20g, Eupolyphaga Seu Steleophaga 10g, Radix Astragali 20g, Radix Codonopsis 20g, Radix Angelicae Sinensis 20g, Radix Rehmanniae Preparata 10g, Radix Dipsaci 20g, Pyritum 10g.
All the other are with embodiment 1
Embodiment 10
Dosage: Radix Notoginseng 20g, Rhizoma Drynariae 15g, Fructus Corni 12g, Radix Salviae Miltiorrhizae 15g, Sanguis Draxonis 10g, Flos Carthami 15g, Eupolyphaga Seu Steleophaga 15g, Radix Astragali 20g, Radix Codonopsis 12g, Radix Angelicae Sinensis 20g, Radix Rehmanniae Preparata 20g, Radix Dipsaci 10g, Pyritum 10g.
All the other are with embodiment 1.
Claims (5)
1. Chinese medicine preparation that blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged is characterized in that the capsule of being made by the Chinese crude drug of following weight ratio:
10～15 parts of Radix Notoginseng, 10～15 parts of Rhizoma Drynariae, 10～15 parts of Fructus Corni, 10～20 parts of Radix Salviae Miltiorrhizaes, 5～15 parts of Sanguis Draxonis, 10～15 parts on Flos Carthami, 5～15 parts of Eupolyphaga Seu Steleophagas, 10～20 parts of the Radixs Astragali, 10～20 parts of Radix Codonopsis, 10～15 parts of Radix Angelicae Sinensis, 10～20 parts of Radix Rehmanniae Preparata, 10～20 parts of Radix Dipsacis, 5～10 parts of Pyritums.
2. according to the described a kind of Chinese medicine preparation that blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged of claim 1, it is characterized in that the capsule of making by the Chinese crude drug of following weight ratio:
12～15 parts of Radix Notoginseng, 12～15 parts of Rhizoma Drynariae, 12～15 parts of Fructus Corni, 17～20 parts of Radix Salviae Miltiorrhizaes, 12～15 parts of Sanguis Draxonis, 12～15 parts on Flos Carthami, 12～15 parts of Eupolyphaga Seu Steleophagas, 17～20 parts of the Radixs Astragali, 17～20 parts of Radix Codonopsis, 12～15 parts of Radix Angelicae Sinensis, 17～20 parts of Radix Rehmanniae Preparata, 17～20 parts of Radix Dipsacis, 8～10 parts of Pyritums.
3. according to the described a kind of Chinese medicine preparation that blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged of claim 1, it is characterized in that the capsule of making by the Chinese crude drug of following weight ratio:
10～13 parts of Radix Notoginseng, 10～13 parts of Rhizoma Drynariae, 10～13 parts of Fructus Corni, 10～15 parts of Radix Salviae Miltiorrhizaes, 5～10 parts of Sanguis Draxonis, 10～13 parts on Flos Carthami, 5～10 parts of Eupolyphaga Seu Steleophagas, 10～15 parts of the Radixs Astragali, 10～15 parts of Radix Codonopsis, 10～13 parts of Radix Angelicae Sinensis, 10～15 parts of Radix Rehmanniae Preparata, 10～15 parts of Radix Dipsacis, 5～8 parts of Pyritums.
4. according to the described a kind of preparation method that the Chinese medicine preparation of blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged of claim 1, it is characterized in that each medical material makes, concocts the back in accordance with regulations only:
(1) take by weighing each medical material by dosage, pulverize separately is to particle diameter 100～150 μ m fine powders, and is standby;
(2) each medical material fine powder of dosage mixes, and stirs evenly, and crosses 120 mesh sieves, and is standby;
(3) with 60 ℃ of oven dry of the medical material fine powder behind the mixing 1 hour, standby;
(4) with the medical material fine powder of oven dry, use ultraviolet radiation sterilization 2 hours, standby;
(5) the medical material fine powder after will sterilizing incapsulates in accordance with regulations; Stipulate down to be up to the standards by pharmacopeia capsule item, promptly get the Chinese medicinal capsule finished product of blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, replenishing QI and blood, reunion of bone.
5. according to claim 1,2 or 3 described a kind of Chinese medicine preparation that blood circulation promoting and blood stasis dispelling reunion of bone effect is arranged, preparing the application for the treatment of in kainogenesis fracture or the old fracture medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102885849A CN102091200B (en) | 2010-09-21 | 2010-09-21 | Chinese medicinal preparation for treating bone fracture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102885849A CN102091200B (en) | 2010-09-21 | 2010-09-21 | Chinese medicinal preparation for treating bone fracture |
Publications (2)
| Publication Number | Publication Date |
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| CN102091200A true CN102091200A (en) | 2011-06-15 |
| CN102091200B CN102091200B (en) | 2012-11-21 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110758A (en) * | 2013-02-04 | 2013-05-22 | 贾荣娟 | External traditional Chinese medicine composition for treating acute lumbar muscle sprain |
| CN103251761A (en) * | 2013-03-08 | 2013-08-21 | 翁捷 | Pharmaceutical composition for preventing and treating fracture nonunion and preparation method thereof |
| CN116211946A (en) * | 2023-03-22 | 2023-06-06 | 杨丽 | Application of traditional Chinese medicine composition in preparation of medicine for promoting fracture healing |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101161273A (en) * | 2007-09-21 | 2008-04-16 | 雷广福 | A Chinese patent medicine for treating catagmat |
| CN101623415A (en) * | 2009-08-07 | 2010-01-13 | 葛超顺 | Traditional Chinese medicine preparation for treating fractures and bone injuries |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101161273A (en) * | 2007-09-21 | 2008-04-16 | 雷广福 | A Chinese patent medicine for treating catagmat |
| CN101623415A (en) * | 2009-08-07 | 2010-01-13 | 葛超顺 | Traditional Chinese medicine preparation for treating fractures and bone injuries |
Non-Patent Citations (2)
| Title |
|---|
| 《中国中医骨伤科杂志》 20060630 龚志贤等 中医药治疗骨折的研究进展 第60-63页 1-5 第14卷, 第3期 2 * |
| 《福建中医药》 19880229 孙绍良 活血化瘀法在骨折上的应用 第40页 1-5 第19卷, 第1期 2 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110758A (en) * | 2013-02-04 | 2013-05-22 | 贾荣娟 | External traditional Chinese medicine composition for treating acute lumbar muscle sprain |
| CN103251761A (en) * | 2013-03-08 | 2013-08-21 | 翁捷 | Pharmaceutical composition for preventing and treating fracture nonunion and preparation method thereof |
| CN116211946A (en) * | 2023-03-22 | 2023-06-06 | 杨丽 | Application of traditional Chinese medicine composition in preparation of medicine for promoting fracture healing |
| CN116211946B (en) * | 2023-03-22 | 2023-09-26 | 杨丽 | Application of traditional Chinese medicine composition in preparation of medicine for promoting fracture healing |
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| CN102091200B (en) | 2012-11-21 |
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