CN102087172A - Quantitative biological sampling flocking swab - Google Patents
Quantitative biological sampling flocking swab Download PDFInfo
- Publication number
- CN102087172A CN102087172A CN2010106045830A CN201010604583A CN102087172A CN 102087172 A CN102087172 A CN 102087172A CN 2010106045830 A CN2010106045830 A CN 2010106045830A CN 201010604583 A CN201010604583 A CN 201010604583A CN 102087172 A CN102087172 A CN 102087172A
- Authority
- CN
- China
- Prior art keywords
- swab
- flocking
- annular support
- cashmere
- biological sampling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000005070 sampling Methods 0.000 title claims abstract description 51
- 239000000835 fiber Substances 0.000 claims description 28
- 239000000463 material Substances 0.000 claims description 11
- 239000004033 plastic Substances 0.000 claims description 6
- 229920003023 plastic Polymers 0.000 claims description 6
- 229920001778 nylon Polymers 0.000 claims description 5
- 239000004793 Polystyrene Substances 0.000 claims description 4
- 229920002223 polystyrene Polymers 0.000 claims description 4
- 239000000758 substrate Substances 0.000 claims description 4
- 229920001617 Vinyon Polymers 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- 239000002131 composite material Substances 0.000 claims description 3
- 229920006351 engineering plastic Polymers 0.000 claims description 3
- 150000003503 terephthalic acid derivatives Chemical class 0.000 claims description 3
- 239000007788 liquid Substances 0.000 abstract description 5
- 230000005540 biological transmission Effects 0.000 description 4
- 230000000274 adsorptive effect Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000005187 foaming Methods 0.000 description 2
- 238000004804 winding Methods 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000000892 gravimetry Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000012858 resilient material Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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Abstract
The invention provides a quantitative biological sampling flocking swab. The swab comprises a swab rod and a swab head, wherein the swab head is a flocking layer covered on the end part of the swab rod; an annular support structure is arranged on end part of one end or two ends of the swab rod; and the flocking layer is covered on the surface of the annular support. The quantitative biological sampling flocking swab can be used for realizing large sampling amount, and controlling l the volume of quantitatively adsorbed liquid to be a set value in a range of between 10 and 200mu l; and the swab head has less possibility of falling off, is convenient to use, and has good safety.
Description
Technical field
The present invention relates to a kind of biological experiment equipment, especially relate to a kind of quantitative biological sampling flocking swab.
Background technology
In field of biology, can the collection of biological specimen (comprising biological cell and biomolecule) and transmission be the most important condition that carry out effective laboratory examination, in numerous biological specimen collections and transmission technology, swab sampling is a kind of the most frequently used and Sampling techniques the most easily, and the swab of wherein sampling is the sampling equipment of most critical.Forming sampling transmission system equipment around the sampling swab can finish by the sampling position and reliably gather biological specimen and safe transfer to breadboard experimentation.
At present, the structure of biological sampling swab commonly used comprises swab handle and swab head.Swab handle is a bar-shaped cylinder, and by tool certain degree of hardness and resilient material, an end is a handgrip part, and one or both ends all can be used as the position that makes the swab head.The swab head is the part that can effectively adsorb biological specimen that is fixed on the swab handle one or both ends, is divided into winding, flocking and foaming three classes.Relatively comprehensive, there is following defective in existing three class biological sampling swabs: (1) winding, flocking or foaming swab head all are distributed in swab handle one end along the swab handle major axis, half of the not enough whole swab head of effective contact portion at swab head and sampling position when reality is used, effective collection liquid sample often causes effective adsorbance deficiency of swab; (2) by twining or the swab head of expanded material parcel combines insecurely with swab handle, the swab head takes place easily come off; (3) existing three class swabs can only saturated samplings and are not possessed the performance of quantitative collection biological specimen; The sampling position might be damaged in the right cylinder top of the swab handle of (4) three class swabs.
Summary of the invention
The objective of the invention is to solve traditional biological sampling swab can not quantitative sampling, the sample adsorbance is low, and solves the swab head and easily come off and unsafe problem.
To achieve these goals, the invention provides a kind of quantitative biological sampling flocking swab, comprise swab handle and swab head, the swab head is the cashmere-planted layer that covers the swab handle end, it is characterized in that: the end of the one or both ends of swab handle is set to the annular support structure, and cashmere-planted layer covers the surface of annular support.
Ring diameter is 1.25～10 mm in the annular support, and annular support cylinder cross-sectional diameter is 0.2～3 mm.
Annular support is 2.5～296 mm as effective flocking area of flocked substrates
2
Annular support is arranged to the above polygon annular in annular, oval ring, three side ring shapes or at least three limits, and annular support cylinder xsect is arranged to circle, ellipse or polygon.
The fibre length of cashmere-planted layer is 0.2～3.0 mm, and the fibre number of cashmere-planted layer is 0.33～7.0 dtex, and the fibre density of cashmere-planted layer is 1.5～350 μ g/mm
2
The material of swab handle is acrylic plastering, vinyon, poly terephthalic acid class plastics, polystyrene plastics or engineering plastics.
Cashmere-planted layer adopts natural fiber, perhaps man-made fiber, and perhaps the composite fibre of the two covers the surface of annular support.
Cashmere-planted layer adopts nylon fiber to cover the surface of annular support.
Swab handle is provided with the mouth that fractures of the swab handle of being convenient to fix a point to fracture, or does not establish the mouth that fractures on the swab handle that can the arbitrfary point fractures with the polystyrene modified plastic production.
Quantitatively ring diameter and annular support cylinder cross-sectional diameter are the effective flocking area of decision and then control collected specimens volume and the principal element that realizes the quantitative collection sample in the annular support of biological sampling flocking swab.In addition, the swab volume that can gather sample also is subjected to the influence of fibre length, fibre number and the fibre density of cashmere-planted layer.With common end is that columned traditional swab head is compared, and is long-pending the increasing of flocked surface of the base material that base material obtained with the annular support, has just increased the efficiently sampling amount by increasing effective flocking area.The present invention is by ring diameter and annular support cylinder cross-sectional diameter in the control annular support, the surface area of flocked substrates is implemented in control, further regulate the variation of fibre number, fibre length and the fibre density of cashmere-planted layer, finally make the swab head possess the quantitative sampling function.According to the swab that principle of the present invention is made, gravimetry (H absorbs water under 25 ℃ of environmental baselines
2O@25 ℃) detected may command quantitative sampling volume is a definite value of 10～200 μ l scopes.
Because the efficiently sampling position of the flocking that the present invention obtains sampling swab concentrates on the swab handle end, can contact fully with being sampled the position when implementing sampling, guarantees fully to gather sample; Owing to adopt the annular support structure, no longer adopt the simple column design of the swab handle end of following for many years, make the swab head both be difficult for coming off and also effectively eliminated the possibility that the swab of sampling causes the injury of sampling position.
The quantitative biological sampling flocking swab that the present invention obtains has the following advantages:
(1) can select the quantitative biological sampling flocking swab of different sampling quantities according to the needs of gathering sample.
(2) quantitatively the swab head active component of biological sampling flocking swab contacts fully with the sampling position, guarantees the sampling quantity maximization.
(3) quantitatively biological sampling flocking swab can the quantitative collection sample, helps to realize that experiment detects directly result of calculation of back.
(4) quantitatively biological sampling flocking swab has solved the loosening and problem that comes off of swab head effectively.
(5) quantitatively biological sampling flocking swab has overcome the problem that swab damages sampling position (as human body) fully.
Description of drawings
Fig. 1 is the structure cut-open view of the embodiment of the invention one.
Fig. 2 is the annular support cylinder cross sectional representation of the embodiment of the invention one.
Fig. 3 is the cut-open view of the annular support of the embodiment of the invention one.
The swab structure cut-open view that Fig. 4 produces for prior art.
Wherein: 1-swab handle, 2-cashmere-planted layer, the 3-mouth that fractures, 4-annular support.
Embodiment
Describe the preferred embodiments of the present invention below with reference to the accompanying drawings in detail.
Embodiment is just like Fig. 1, Fig. 2, shown in Figure 3, present embodiment provides a kind of quantitative biological sampling flocking swab, comprise swab handle 1 and swab head, annular support 4 is arranged in the end of one end of swab handle 1, perhaps also the end at swab handle 1 two ends can be arranged to annular support 4 respectively, the ring-type of the annular support 4 of present embodiment is arranged to annular, perhaps also can be arranged to the above polygon annular in oval ring, three side ring shapes or at least three limits; Annular support 4 cylinder xsects are arranged to circle, perhaps also can be arranged to ellipse or polygon.
Ring diameter can be arranged between 1.25～10 mm scopes in the annular support 4 of present embodiment, and present embodiment is set to 3.91 mm; Annular support 4 cylinder cross-sectional diameters can be arranged between 0.2～3 mm scope, and present embodiment is set to 1.19 mm; Swab handle 1 and annular support 4 can adopt vinyon, poly terephthalic acid class plastics or engineering plastics, present embodiment adopts the acrylic plastering material to make, and fracture mouthfuls 3 what swab handle 1 part was provided with the swab handle 1 of being convenient to fix a point to fracture as required, use with the transmission after the convenient sampling; Perhaps also can adopt the swab handle 1 of polystyrene modified made to fracture to be implemented in the arbitrfary point.
With annular support 4 is base material, makes cashmere-planted layer 2 cover the surface of annular support 4 base materials, and effective cashmere-planted layer area of annular support 4 substrate surfaces can be arranged on 2.5～296 mm
2Between the scope, present embodiment is 46 mm
2The fibre length of cashmere-planted layer 2 can be arranged between 0.2～3.0 mm scope, and present embodiment is 0.6 mm; The fibre number of cashmere-planted layer 2 can be arranged between 0.33～7.0 dtex scope, and present embodiment is 1.5 dtex; The fibre density of cashmere-planted layer 2 can be arranged on 1.5～350 μ g/mm
2Between the scope, present embodiment is 17 μ g/mm
2The material that swab head cashmere-planted layer 2 relates to is a natural fiber, perhaps man-made fiber, and the perhaps composite fibre of the two, present embodiment is a nylon fiber.
Compare with traditional swab shown in Figure 4, the advantage of present embodiment show as sampling quantity big, can determine that quantitatively the liquid volume of absorption is 55 μ l(H
2O@25 ℃), swab head difficult drop-off, easy to use and security good.
Embodiment two, ring diameter 5 mm in the annular support 4, and annular support 4 cylinder cross-sectional diameters 1.5 mm, the effective flocking area of the base material of annular support 4 is 74 mm
2, nylon fiber length 1.5 mm, fibre number 6.67 dtex, the fibre density 328 μ g/mm of cashmere-planted layer 2
2, adsorptive liquid volume 110 μ l(H
2O@25 ℃), all the other are with embodiment one.
Embodiment three, ring diameter 1.5 mm in the annular support 4, and annular support 4 cylinder cross-sectional diameters 0.5 mm, the effective flocking area of the base material of annular support 4 is 7.39 mm
2, nylon fiber length 1.0 mm, fibre number 1.5 dtex, the fibre density 109 μ g/mm of cashmere-planted layer 2
2, adsorptive liquid volume 20 μ l(H
2O@25 ℃), all the other are with embodiment one.
Claims (8)
1. quantitative biological sampling flocking swab, comprise swab handle (1) and swab head, the swab head is the cashmere-planted layer that covers the swab handle end, it is characterized in that: the end of the one or both ends of swab handle (1) is set to annular support (4) structure, and cashmere-planted layer (2) covers the surface of annular support (4).
2. quantitative biological sampling flocking swab according to claim 1 is characterized in that: the interior ring diameter of annular support (4) is 1.25～10 mm, and annular support (4) cylinder cross-sectional diameter is 0.2～3 mm.
3. quantitative biological sampling flocking swab according to claim 1 is characterized in that: annular support (4) is 2.5～296 mm as effective flocking area of flocked substrates
2
4. according to claim 1 or 2 or 3 described quantitative biological sampling flocking swabs, it is characterized in that: annular support (4) is arranged to the above polygon annular in annular, oval ring, three side ring shapes or at least three limits, and annular support (4) cylinder xsect is arranged to circle, ellipse or polygon.
5. according to claim 1 or 2 or 3 described quantitative biological sampling flocking swabs, it is characterized in that: the fibre length of cashmere-planted layer (2) is 0.2～3.0 mm, the fibre number of cashmere-planted layer (2) is 0.33～7.0 dtex, and the fibre density of cashmere-planted layer (2) is 1.5～350 μ g/mm
2
6. quantitative biological sampling flocking swab according to claim 1 is characterized in that: the material of swab handle (1) is acrylic plastering, vinyon, poly terephthalic acid class plastics, polystyrene plastics or engineering plastics.
7. quantitative biological sampling flocking swab according to claim 1 is characterized in that: cashmere-planted layer (2) adopts natural fiber, perhaps man-made fiber, and perhaps the composite fibre of the two covers the surface of annular support (4).
8. according to claim 1 or 7 described quantitative biological sampling flocking swabs, it is characterized in that: cashmere-planted layer (2) adopts nylon fiber to cover the surface of annular support (4).
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010604583.0A CN102087172B (en) | 2010-12-24 | 2010-12-24 | Quantitative biological sampling flocking swab |
| PCT/CN2011/000203 WO2012083572A1 (en) | 2010-12-24 | 2011-02-09 | Flocking swab for biological sampling quantitatively and method for making the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010604583.0A CN102087172B (en) | 2010-12-24 | 2010-12-24 | Quantitative biological sampling flocking swab |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102087172A true CN102087172A (en) | 2011-06-08 |
| CN102087172B CN102087172B (en) | 2016-09-07 |
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ID=44099070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201010604583.0A Active CN102087172B (en) | 2010-12-24 | 2010-12-24 | Quantitative biological sampling flocking swab |
Country Status (1)
| Country | Link |
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| CN (1) | CN102087172B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107249472A (en) * | 2015-02-19 | 2017-10-13 | 恩姆菲舍尔科技公司 | The assembly of sampling apparatus and sampling apparatus and sample container |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2460050Y (en) * | 2001-01-18 | 2001-11-21 | 江苏苏云医疗器材有限公司 | Medical sampling swab |
| CN1325287A (en) * | 1998-07-23 | 2001-12-05 | 奥乐斯堪/崔龙合资企业公司 | Apparatus and method for obtaining transepithelia L specimen of a body surface using a non-lacerating technique |
| CN201085636Y (en) * | 2007-09-25 | 2008-07-16 | 王学礼 | Disposal bone shaped neck of uterus flighter |
| CN101243982A (en) * | 2008-03-21 | 2008-08-20 | 周星 | Uterine cervix brush |
| CN201993241U (en) * | 2010-12-24 | 2011-09-28 | 江苏世泰实验器材有限公司 | Quantitative biological sampling flocked swab |
-
2010
- 2010-12-24 CN CN201010604583.0A patent/CN102087172B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1325287A (en) * | 1998-07-23 | 2001-12-05 | 奥乐斯堪/崔龙合资企业公司 | Apparatus and method for obtaining transepithelia L specimen of a body surface using a non-lacerating technique |
| CN2460050Y (en) * | 2001-01-18 | 2001-11-21 | 江苏苏云医疗器材有限公司 | Medical sampling swab |
| CN201085636Y (en) * | 2007-09-25 | 2008-07-16 | 王学礼 | Disposal bone shaped neck of uterus flighter |
| CN101243982A (en) * | 2008-03-21 | 2008-08-20 | 周星 | Uterine cervix brush |
| CN201993241U (en) * | 2010-12-24 | 2011-09-28 | 江苏世泰实验器材有限公司 | Quantitative biological sampling flocked swab |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107249472A (en) * | 2015-02-19 | 2017-10-13 | 恩姆菲舍尔科技公司 | The assembly of sampling apparatus and sampling apparatus and sample container |
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| Publication number | Publication date |
|---|---|
| CN102087172B (en) | 2016-09-07 |
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| TR01 | Transfer of patent right |
Effective date of registration: 20240102 Address after: 226100 No.48, Xinxiu Road, Haimen street, Haimen District, Nantong City, Jiangsu Province Patentee after: Jiangsu yingwotai Biotechnology Co.,Ltd. Address before: No. 48 Xinxiu Road, Haimen City, Nantong City, Jiangsu Province, 226100 Patentee before: CITOTEST LABWARE MANUFACTURING Co.,Ltd. |
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| TR01 | Transfer of patent right |