CN102085314B - Chinese medicine for treating drug-resistant staphylococcus aureus septicemia - Google Patents

Chinese medicine for treating drug-resistant staphylococcus aureus septicemia Download PDF

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CN102085314B
CN102085314B CN 201010623393 CN201010623393A CN102085314B CN 102085314 B CN102085314 B CN 102085314B CN 201010623393 CN201010623393 CN 201010623393 CN 201010623393 A CN201010623393 A CN 201010623393A CN 102085314 B CN102085314 B CN 102085314B
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medicinal liquid
radix
staphylococcus aureus
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chinese medicine
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CN102085314A (en
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屈凤星
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Abstract

The invention discloses a Chinese medicine for treating drug-resistant staphylococcus aureus septicemia and relates to the field of Chinese patent drugs, solving the problems of toxic and side effects, long treatment course, poor curative effect, high cost, and the like of medicaments frequently used for treating the drug-resistant staphylococcus aureus septicemia by people at present. The Chinese medicine is prepared by the following steps of: respectively screening raw material medicines of Polygonum cuspidatum, raw rhizoma rehmanniae, chrysanthemums, herba violae, and the like, removing impurities, washing clean, and cutting up; adding a proper quantity of water into a ceramic utensil and soaking the raw materials for 20-30 minutes; boiling the raw materials to 100 DEG C and then continuing to decoct for 20-30 minutes; filtering out liquid medicine to obtain first liquid medicine; decocting residual dregs to obtain second liquid medicine; decocting residual dregs to obtain third liquid medicine; and mixing the three liquid medicines to obtain the Chinese medicine for treating drug-resistant staphylococcus aureus septicemia. The Chinese medicine for treating the drug-resistant staphylococcus aureus septicemia has the advantages of short treatment course, no toxic and side effects, difficult recurrence, rich medicine source and low cost.

Description

A kind of Chinese medicine for the treatment of the drug resistance staphylococcus aureus septicemia
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of the fastbacteria septicemia, particularly relate to a kind of Chinese medicine of drug resistance staphylococcus aureus septicemia.
Background technology
In medical practice, the part patient of some patient, particularly acute leukemia, chronic leukemia, aplastic anemia and hypoimmunity is taken place by drug resistance infection of staphylococcus aureus and heating, severe patient even the septicemia symptom occurs.Modern doctor trained in Western medicine adopts the medicine of antibiotic aspects such as some erythromycin, safe energy, vancomycin or cephalosporins to treat more, and clinical effectiveness is also very undesirable, also can show effect repeatedly, but these medicines is taken for a long time and can be caused damage to liver, kidney and other organs.Though also there is the Chinese patent medicine of some treatment antibacterials traditional Chinese medical science aspect, weak curative effect does not reach desirable effect.
Summary of the invention
The objective of the invention is provides a kind of cost low in order to overcome deficiency of the prior art, and curative effect is obvious, the Chinese medicine of short treating period, the treatment drug resistance staphylococcus aureus septicemia that has no side effect.
For achieving the above object, the invention provides a kind of Chinese medicine for the treatment of the drug resistance staphylococcus aureus septicemia, made by following material medicine, its weight portion is:
Figure GSB00000923297000011
The composition by weight of each material medicine of optimum formula of the present invention is:
Figure GSB00000923297000022
The preparation method of Chinese medicine for the treatment of drug resistance staphylococcus aureus septicemia comprises the steps:
(1) with arrangement after impurity is removed in screening, the chopping respectively of Rhizoma Polygoni Cuspidati, Radix Rehmanniae, Flos Chrysanthemi, Herba Violae, Herba Taraxaci, Herba Epimedii, Poria, Rhizoma Phragmitis, Rhizoma Coptidis, Cortex Phellodendri, Radix Sophorae Flavescentis, Herba Houttuyniae, Herba Hedyotidis Diffusae, Radix Scrophulariae, Rhizoma Atractylodis, Radix Salviae Miltiorrhizae, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Radix Glehniae, Radix Polygalae, Radix Ophiopogonis, Rhizoma Polygonati Odorati material medicine;
(2) material medicine after above-mentioned arrangement, the chopping is placed in described ratio adds suitable quantity of water in the pottery and soaked 20~30 minutes;
(3) Gypsum Fibrosum of described ratio is ground to form that powdery adds suitable quantity of water and it is boiled to continue to decoct after 100 ℃ be added to above-mentioned being placed with in the pottery that is soaked 20~30 minutes material medicines after 20~30 minutes, again it is boiled and continue after 100 ℃ to decoct 20~30 minutes, leach the medicinal liquid juice medicinal liquid of namely winning;
(4) the described recrement that leaches behind the first juice medicinal liquid is added suitable quantity of water, again it is boiled after 100 ℃ and continue to decoct 20~30 minutes, leach medicinal liquid and namely get the second juice medicinal liquid;
(5) the described recrement that leaches behind the second juice medicinal liquid is added suitable quantity of water, again it is boiled after 100 ℃ and continue to decoct 20~30 minutes, leach medicinal liquid and namely get the 3rd juice medicinal liquid;
(6) the described first juice medicinal liquid, the second juice medicinal liquid and the 3rd juice medicinal liquid are mixed the Chinese medicine that namely gets treatment drug resistance staphylococcus aureus septicemia.
During with herb liquid of the present invention, natural gift take for three times, and seven days is a course for the treatment of, and medication is decided on state of an illness weight, generally take after three days body temperature and are down to normally, and weight person can fully recover one or two course for the treatment of.
The material medicine mechanism that the present invention adopts is as follows:
Gypsum Fibrosum acrid in the mouth, sweet, cold nature, clearing away heat-fire, relieving restlessness is quenched the thirst, and skin ulcer is held back in heat clearing away; The Rhizoma Polygoni Cuspidati mildly bitter flavor, cold nature, promoting the function of the gallbladder to alleviate jaundice, heat-clearing and toxic substances removing, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, expelling phlegm for arresting cough; Radix Rehmanniae sweet in the mouth, hardship, cold in nature, clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; Flos Chrysanthemi acrid in the mouth, sweet, bitter, cold nature, the vegetables wind heat of loosing, suppressing liver-YANG, liver heat removing and eyesight improving, heat-clearing and toxic substances removing; Herba Violae bitter in the mouth, suffering, cold in nature, heat-clearing and toxic substances removing, removing heat from blood detumescence; Herba Taraxaci sweet in the mouth, little hardship, cold in nature, heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, eliminating damp-heat; Herba Epimedii acrid in the mouth, sweet, warm in nature, kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Poria sweet in the mouth, light, property is flat, promoting diuresis to eliminate damp pathogen, spleen-benefiting mind-tranquilizing, heat-clearing and toxic substances removing; The Rhizoma Phragmitis sweet in the mouth, cold in nature, clearing away heat and promoting production of body fluid, clearing stomach preventing or arresting vomiting, lung heat clearing evacuation of pus, diuresis; The Rhizoma Coptidis bitter in the mouth, cold, heat clearing and damp drying, eliminating fire and detoxication; The Cortex Phellodendri bitter in the mouth, cold in nature, heat clearing and damp drying, eliminating fire and detoxication, reducing the asthenic fever; The Radix Sophorae Flavescentis bitter in the mouth, cold in nature, heat clearing and damp drying, wind dispelling insecticide, diuresis; The Herba Houttuyniae bitter in the mouth, cold nature, heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome; Herba Hedyotidis Diffusae bitter in the mouth, sweet, cold in nature, heat clearing away, the pain that disappears, dampness removing is treating stranguria; The Radix Scrophulariae sweet in the mouth, bitter, one-tenth, cold nature, clearing away heat and cooling blood, nourishing YIN to lower pathogenic fire, eliminating fire and detoxication; Rhizoma Atractylodis acrid in the mouth, hardship, warm in nature, drying damp and strengthening spleen, wind-damp dispelling, detoxifcation; The Radix Salviae Miltiorrhizae bitter in the mouth, cold nature, blood circulation promoting and blood stasis dispelling, cool seroma, clearing away heart-fire for tranquillization; Radix Astragali sweet in the mouth, slightly warm in nature, invigorating the spleen and replenishing QI, benefiting QI for strengthening the superficies, diuretic detumescent, toxin expelling granulation promoting; Rhizoma Atractylodis Macrocephalae bitter in the mouth, sweet, warm in nature, invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive; The Radix Glycyrrhizae sweet in the mouth, property is flat, invigorating the spleen and replenishing QI, expelling phlegm for arresting cough, relieving spasm to stop pain, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription; Radix Glehniae sweet in the mouth, little hardship, cold nature, nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid; Radix Polygalae bitter in the mouth, suffering, slightly warm in nature, the Fructus Alpiniae Oxyphyllae of calming the nerves is eliminated the phlegm, detumescence; Radix Ophiopogonis sweet in the mouth, little hardship, cold nature, YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire; The Rhizoma Polygonati Odorati sweet in the mouth, property is flat, nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
Therefore 1, because the present invention has adopted the above-mentioned raw materials medicine to carry out compatibility, it is obvious to treat drug resistance staphylococcus aureus septicemia curative effect, short treating period, has alleviated patient's misery.
2, herb liquid property of medicine moderate notoxic of the present invention side effect can not cause damage to liver, kidney.
3, medicine of the present invention source is abundant, manufacture method is simple and easy to do, uses safety, and is with low cost.
The present invention through 1976 so far the application examples of 516 routine patient's clinical treatments further specify Chinese medicine of the present invention to the therapeutic effect for the treatment of drug resistance staphylococcus aureus septicemia.
Patient's 230 examples of septicemia symptom appear in acute leukemia, male's 120 examples wherein, and women's 110 examples, the age, the course of disease was 20 days~80 days at 28~67 years old, after the Chinese medicine with treatment drug resistance staphylococcus aureus septicemia, wherein recurrence is not seen in 217 recoveries from illness.
Patient's 65 examples of septicemia symptom appear in chronic myelocytic leukemia, male's 34 examples wherein, women's 31 examples, the age, the course of disease was 1 month~3 months at 34~60 years old, with behind this medicine wherein 57 people recovery from illness do not see recurrence so far.
Patient's 188 examples of septicemia symptom appear in aplastic anemia, male's 102 examples wherein, women's 86 examples, the age was at 5 years old~60 years old, the course of disease is 1 month~70 days, recovers normally not see so far recurrence with 171 example examples behind the Chinese medicine for the treatment of drug resistance staphylococcus aureus septicemia.
Patient's 33 examples of septicemia symptom appear in hypoimmunity, male's 25 examples wherein, women's 8 examples, the age is at 11~78 years old, the course of disease is two weeks~80 day, with behind this medicine wherein 28 examples recover normally not see so far recurrence.
The clinical data summary sheet:
Title Case Recovery from illness Cure rate
The concurrent septicemia of acute leukemia 230 217 94%
The concurrent septicemia of chronic myelocytic leukemia 65 57 88%
The concurrent septicemia of aplastic anemia 188 171 91%
The concurrent septicemia of hypoimmunity 33 28 85%
The specific embodiment
Embodiment one: put in order after will removing impurity, Rhizoma Polygoni Cuspidati 10 grams of chopping, Radix Rehmanniae 10 grams, Flos Chrysanthemi 7 grams, Herba Violae 15 grams, Herba Taraxaci 10 grams, Herba Epimedii 5 grams, Poria 7 grams, Rhizoma Phragmitis 10 grams, Rhizoma Coptidis 1 gram, Cortex Phellodendri 7 grams, Radix Sophorae Flavescentis 3 grams, Herba Houttuyniae 15 grams, Herba Hedyotidis Diffusae 10 grams, Radix Scrophulariae 15 grams, Rhizoma Atractylodis 10 grams, Radix Salviae Miltiorrhizae 10 grams, the Radix Astragali 15 grams, the Rhizoma Atractylodis Macrocephalae 7 grams, Radix Glycyrrhizae 1 gram, Radix Glehniae 3 grams, Radix Polygalae 3 grams, restrain Radix Ophiopogonis 7, Rhizoma Polygonati Odorati 7 grams are placed on and add suitable quantity of water immersion 20~30 minutes in the pottery; Gypsum Fibrosum 15 gram ground to form that powdery adds suitable quantity of water and it is boiled to continue to decoct after 100 ℃ and be added to above-mentioned being placed with in the pottery that is soaked 20~30 minutes material medicines after 20~30 minutes, again it is boiled and continue after 100 ℃ to decoct 20 minutes, leach the medicinal liquid juice medicinal liquid of namely winning; The described recrement that leaches behind the first juice medicinal liquid is added suitable quantity of water, again it is boiled after 100 ℃ and continue to decoct 30 minutes, leach medicinal liquid and namely get the second juice medicinal liquid; The described recrement that leaches behind the second juice medicinal liquid is added suitable quantity of water, again it is boiled after 100 ℃ and continue to decoct 25 minutes, leach medicinal liquid and namely get the 3rd juice medicinal liquid; The described first juice medicinal liquid, the second juice medicinal liquid and the 3rd juice medicinal liquid are mixed the Chinese medicine that namely gets treatment drug resistance staphylococcus aureus septicemia.
Embodiment two: put in order after will removing impurity, Rhizoma Polygoni Cuspidati 15 grams of chopping, Radix Rehmanniae 15 grams, Flos Chrysanthemi 12 grams, Herba Violae 20 grams, Herba Taraxaci 15 grams, Herba Epimedii 10 grams, Poria 12 grams, Rhizoma Phragmitis 15 grams, Rhizoma Coptidis 5 grams, Cortex Phellodendri 12 grams, Radix Sophorae Flavescentis 8 grams, Herba Houttuyniae 20 grams, Herba Hedyotidis Diffusae 15 grams, Radix Scrophulariae 20 grams, Rhizoma Atractylodis 15 grams, Radix Salviae Miltiorrhizae 15 grams, the Radix Astragali 20 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Radix Glycyrrhizae 6 grams, Radix Glehniae 8 grams, Radix Polygalae 8 grams, restrain Radix Ophiopogonis 12, Rhizoma Polygonati Odorati 12 grams are placed on and add suitable quantity of water immersion 20~30 minutes in the pottery; Gypsum Fibrosum 20 gram ground to form that powdery adds suitable quantity of water and it is boiled to continue to decoct after 100 ℃ and be added to above-mentioned being placed with in the pottery that is soaked 20~30 minutes material medicines after 20~30 minutes, again it is boiled and continue after 100 ℃ to decoct 25 minutes, leach the medicinal liquid juice medicinal liquid of namely winning; The described recrement that leaches behind the first juice medicinal liquid is added suitable quantity of water, again it is boiled after 100 ℃ and continue to decoct 30 minutes, leach medicinal liquid and namely get the second juice medicinal liquid; The described recrement that leaches behind the second juice medicinal liquid is added suitable quantity of water, again it is boiled after 100 ℃ and continue to decoct 30 minutes, leach medicinal liquid and namely get the 3rd juice medicinal liquid; The described first juice medicinal liquid, the second juice medicinal liquid and the 3rd juice medicinal liquid are mixed the Chinese medicine that namely gets treatment drug resistance staphylococcus aureus septicemia.
Embodiment three: put in order after will removing impurity, Rhizoma Polygoni Cuspidati 20 grams of chopping, Radix Rehmanniae 20 grams, Flos Chrysanthemi 17 grams, Herba Violae 25 grams, Herba Taraxaci 20 grams, Herba Epimedii 15 grams, Poria 17 grams, Rhizoma Phragmitis 20 grams, Rhizoma Coptidis 10 grams, Cortex Phellodendri 17 grams, Radix Sophorae Flavescentis 13 grams, Herba Houttuyniae 25 grams, Herba Hedyotidis Diffusae 20 grams, Radix Scrophulariae 25 grams, Rhizoma Atractylodis 20 grams, Radix Salviae Miltiorrhizae 20 grams, the Radix Astragali 25 grams, the Rhizoma Atractylodis Macrocephalae 17 grams, Radix Glycyrrhizae 11 grams, Radix Glehniae 13 grams, Radix Polygalae 13 grams, restrain Radix Ophiopogonis 17, Rhizoma Polygonati Odorati 17 grams are placed on and add suitable quantity of water immersion 20~30 minutes in the pottery; Gypsum Fibrosum 2 gram ground to form that powdery adds suitable quantity of water and it is boiled to continue to decoct after 100 ℃ and be added to above-mentioned being placed with in the pottery that is soaked 20~30 minutes material medicines after 20~30 minutes, again it is boiled and continue after 100 ℃ to decoct 25 minutes, leach the medicinal liquid juice medicinal liquid of namely winning; The described recrement that leaches behind the first juice medicinal liquid is added suitable quantity of water, again it is boiled after 100 ℃ and continue to decoct 30 minutes, leach medicinal liquid and namely get the second juice medicinal liquid; The described recrement that leaches behind the second juice medicinal liquid is added suitable quantity of water, again it is boiled after 100 ℃ and continue to decoct 30 minutes, leach medicinal liquid and namely get the 3rd juice medicinal liquid; The described first juice medicinal liquid, the second juice medicinal liquid and the 3rd juice medicinal liquid are mixed the Chinese medicine that namely gets treatment drug resistance staphylococcus aureus septicemia.

Claims (3)

1. a Chinese medicine for the treatment of the drug resistance staphylococcus aureus septicemia is characterized in that, is made by following material medicine, and its weight portion is:
Figure FSB00000923296800011
2. the Chinese medicine for the treatment of drug resistance staphylococcus aureus septicemia according to claim 1 is characterized in that, the composition by weight of described material medicine is:
Figure FSB00000923296800012
3. the preparation method of Chinese medicine for the treatment of drug resistance staphylococcus aureus septicemia according to claim 1 is characterized in that, comprises the steps:
(1) with arrangement after impurity is removed in screening, the chopping respectively of Rhizoma Polygoni Cuspidati, Radix Rehmanniae, Flos Chrysanthemi, Herba Violae, Herba Taraxaci, Herba Epimedii, Poria, Rhizoma Phragmitis, Rhizoma Coptidis, Cortex Phellodendri, Radix Sophorae Flavescentis, Herba Houttuyniae, Herba Hedyotidis Diffusae, Radix Scrophulariae, Rhizoma Atractylodis, Radix Salviae Miltiorrhizae, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Radix Glehniae, Radix Polygalae, Radix Ophiopogonis, Rhizoma Polygonati Odorati material medicine;
(2) material medicine after above-mentioned arrangement, the chopping is placed in described ratio adds suitable quantity of water in the pottery and soaked 20~30 minutes;
(3) Gypsum Fibrosum of described ratio is ground to form that powdery adds suitable quantity of water and it is boiled to continue to decoct after 100 ℃ be added to above-mentioned being placed with in the pottery that is soaked 20~30 minutes material medicines after 20~30 minutes, again it is boiled and continue after 100 ℃ to decoct 20~30 minutes, leach the medicinal liquid juice medicinal liquid of namely winning;
(4) the described recrement that leaches behind the first juice medicinal liquid is added suitable quantity of water, again it is boiled after 100 ℃ and continue to decoct 20~30 minutes, leach medicinal liquid and namely get the second juice medicinal liquid;
(5) the described recrement that leaches behind the second juice medicinal liquid is added suitable quantity of water, again it is boiled after 100 ℃ and continue to decoct 20~30 minutes, leach medicinal liquid and namely get the 3rd juice medicinal liquid;
(6) the described first juice medicinal liquid, the second juice medicinal liquid and the 3rd juice medicinal liquid are mixed the Chinese medicine that namely gets treatment drug resistance staphylococcus aureus septicemia.
CN 201010623393 2010-12-27 2010-12-27 Chinese medicine for treating drug-resistant staphylococcus aureus septicemia Expired - Fee Related CN102085314B (en)

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CN103610984B (en) * 2013-12-04 2015-10-14 辛荣 A kind of oral liquid and preparation method for the treatment of septicemia

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
宋金涛等.变应性亚败血症治验及讨论.《天津中医药》.1986,(第06期),15,16,19. *
薛仁民等.中西医配合治疗重症金黄色葡萄状球菌败血症一例.《福建中医药》.1960,(第03期),18. *
顾庆华.防风通圣散治变应性亚败血症.《福建中医药》.1991,第22卷(第05期),55. *

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