CN102078525A - Medicine combination for treating wind-heat type common cold - Google Patents

Medicine combination for treating wind-heat type common cold Download PDF

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Publication number
CN102078525A
CN102078525A CN2009102520014A CN200910252001A CN102078525A CN 102078525 A CN102078525 A CN 102078525A CN 2009102520014 A CN2009102520014 A CN 2009102520014A CN 200910252001 A CN200910252001 A CN 200910252001A CN 102078525 A CN102078525 A CN 102078525A
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parts
radix
medicine combination
wind
anemopyretic cold
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CN2009102520014A
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王小华
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Abstract

The invention relates to a medicine combination, in particular to a medicine combination for treating wind-heat type common cold which comprises the following active pharmaceutical ingredients in parts by weight: 40-80 parts of mulberry leaf, 20-40 parts of chrysanthemum, 10-18 parts of mint, 10-30 parts of radix bupleuri, 10-24 parts of reed rhizome, 10-24 parts of radix isatidis, 10-20 parts of honeysuckles, 10-20 parts of weeping forsythia, 10-20 parts of duckweed, 10-20 parts of radix saposhnikoviae, 10-20 parts of almond and 3-9 parts of liquorice. The medicine combination has the strong effects of relieving the exterior syndrome because the medicine combination is pungent in flavor and cool in property and clearing away the heat and toxic materials, is used for diseases caused by wind-heat type common cold, such as fever with ill wind, headache and body pain, cough with dry throat, swollen sore throat and the like and has obvious curative effect.

Description

A kind of pharmaceutical composition for the treatment of anemopyretic cold
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of pharmaceutical composition for the treatment of anemopyretic cold.
Background technology
Flu is common exterior syndromes of the four seasons, sees with winter and spring especially more, and the flu onset is more anxious, and early symptom has pharyngeal dried itching or burning sensation, sneeze, nasal obstruction, watery nasal discharge, can be with pharyngalgia, and flu also is a kind of acute infection rhinitis, is commonly called as " cold ".The traditional Chinese medical science thinks that flu generally can be divided into anemofrigid cold and anemopyretic cold two big classes.These two kinds flu etiology and pathogenesis, symptom, Therapeutic Principle and medication difference are very big.Anemopyretic cold, be the heresy invasion and attack human body of wind heat caused with generate heat heavily, aversion to cold is light or sweating not smooth etc. be the common exterior syndrome of main clinical manifestation.
The wind heat diseases caused by exogenous pathogenic factor, pilosity is born in spring.Spring is windy, and weather changes temperature, so wind and warm heterogeneous double the causing a disease of heresy.Anemopyretic cold is that the heresy invasion and attack lung of wind heat is defended, and causes and defends the table discord, impairment of purifying function of the lung and the syndrome that occurs.Its clinical manifestation is: onset is anxious, it is fast to change, aversion to cold is light, heating is heavy, headache, cough expectorant Huang, laryngopharynx swelling and pain, thirsty, yellowish urine, red tip of the tongue, floating and rapid pulse, should be fundamentum with relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, heat-clearing and toxic substances removing in treatment.
The purpose that though the Chinese patent medicine side effect is little, can reach treating both the principal and secondary aspects of a disease, because there is very big-difference in Chinese patent medicine in choosing side, different prescribed treatment effects have very large difference.So give full play to the Chinese medicine characteristics,, prepare Chinese medicine composition evident in efficacy and be necessary in conjunction with modern formulation process method.
Summary of the invention
Purpose of the present invention provides the pharmaceutical composition of a kind of determined curative effect, cure rate height, treatment anemopyretic cold that relapse rate is low.
To achieve these goals, the invention provides following technical scheme:
A kind of pharmaceutical composition for the treatment of anemopyretic cold, it is the medicament of being made by following bulk drugs thing:
Folium Mori 40-80 part, Flos Chrysanthemi 20-40 part, Herba Menthae 10-18 part, Radix Bupleuri 10-30 part, Rhizoma Phragmitis 10-24 part, Radix Isatidis 10-24 part, Flos Lonicerae 10-20 part, Fructus Forsythiae 10-20 part, Herba Spirodelae 10-20 part, Radix Saposhnikoviae 10-20, Semen Armeniacae Amarum 10-20 part, Radix Glycyrrhizae 3-9 part.
Preferably, the Chinese medicine composition of treatment anemopyretic cold of the present invention is made by following bulk drugs thing:
Folium Mori 30-60 part, Flos Chrysanthemi 30-35 part, Herba Menthae 12-15 part, Radix Bupleuri 12-25 part, Rhizoma Phragmitis 12-18 part, Radix Isatidis 12-18 part, Flos Lonicerae 12-18 part, Fructus Forsythiae 12-18 part, Herba Spirodelae 12-18 part, Radix Saposhnikoviae 12-18, Semen Armeniacae Amarum 12-18 part, Radix Glycyrrhizae 5-7 part.
Preferably, the Chinese medicine composition of treatment anemopyretic cold of the present invention is made by following bulk drugs thing:
45 parts on Folium Mori, 32 parts of Flos Chrysanthemis, 14 parts of Herba Menthaes, 18 parts of Radix Bupleuri, 15 parts of Rhizoma Phragmitiss, 15 parts of Radix Isatidis, 15 parts of Flos Loniceraes, 15 parts of Fructus Forsythiaes, 15 parts in Herba Spirodelae, Radix Saposhnikoviae 15,15 parts in Semen Armeniacae Amarum, 15 parts in Radix Glycyrrhizae.
Pharmaceutical composition of the present invention, can be according to the pharmaceutics preparation technology of routine, be prepared into any pharmaceutical dosage form that is suitable for using clinically, as decoction, tablet, teabag, oral solutions, pill, powder, capsule, drop pill, mixture, drink agent, granule etc.
Anemopyretic cold all can take place throughout the year, and more to see spring more.How by abrupt change of climate, cold warm imbalance, the heresy of wind heat seizes the opportunity to worm one's way into human body, attacks lung and violates and defend, and Wei Yangyu holds back, and battalion defends and becomes estranged, struggle between vital QI and pathogen, and see Table the card of defending.Wind is first of the six climate exopathogens, and is though convict and causing a disease separately clinically sees that combined pathogens is a trouble more, more common with the wind heat combined pathogens especially.The people of essence and blood body fluid void and deficiency of YIN body constitution in clinical, susceptible is subjected to the heresy of wind heat.Wind is master's gas in spring, and anemopyretic cold whenever is easy to illly in spring, be the characteristics in its season.
The Chinese medicine composition of treatment anemopyretic cold of the present invention is based on understanding and the Therapeutic Principle of traditional traditional Chinese medical science to anemopyretic cold, achieve with reference to modern pharmacological research, from motherland's medicine and pharmacology treasure-house, filter out the medicine that has wind and heat dispersing, moistens dryness and relieve cough, form according to the theory of Chinese medical science prescription.
In the pharmaceutical composition of the present invention, pharmaceutical composition Folium Mori of the present invention, Flos Chrysanthemi, Herba Menthae have the effect of wind-dispelling heat-dissipating, clearing away lung-heat and moistening for dryness; The Radix Bupleuri reconciling superficies and interior, soothing the liver, yang invigorating; Rhizoma Phragmitis has the lung heat clearing gastric heat, promoting the production of body fluid to quench thirst, and it is thirsty to be used for the epidemic febrile disease hyperpyrexia, gastropyretic vomiting, and the cough due to lung-heat, expectorant is thick and diseases such as Huang; Radix Isatidis has heat-clearing and toxic substances removing, removing heat from blood, is used for warm heating, sends out speckle, anemopyretic cold; Semen Armeniacae Amarum has antitussive and antiasthmatic, clear and rich lung relieves inflammation or internal heat, the effect of catharsis and toxin expelling.The Fructus Forsythiae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Be used for affection due to external wind and heat, laryngopharynx swelling and pain.Behind each components compatibility of Chinese medicine compositions of the present invention antipyretic and antidote functions is preferably arranged, can bring down a fever rapidly, mitigation symptoms shortens the course of disease.Herba Spirodelae, Radix Saposhnikoviae dispelling wind and heat pathogens assistant, Radix Glycyrrhizae detoxifcation and coordinating the actions of various ingredients in a prescription.
Take the present invention of above-mentioned measure, have stronger relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, heat-clearing toxin-expelling functions is used for the disease such as fever and aversion to wind, head-body-pain, cough dry pharynx, laryngopharynx swelling and pain due to the anemopyretic cold, determined curative effect.Show through results of pharmacodynamic test: pharmaceutical composition decocting liquid gastric infusion of the present invention all has certain refrigeration function to the fever in rabbits due to rat fever due to the yeast and the bacterial endotoxin, can strengthen the Turnover of Mouse Peritoneal Macrophages phagocytic function; The cough that mice sulfur dioxide is caused has certain antitussive action; Staphylococcus aureus and escherichia coli there is certain external bacteriostasis; Chick embryo method examination face has been observed the effect of resisiting influenza virus of the present invention, and the result shows that the present invention infects Embryo Gallus domesticus to Influenza B virus preventive effect is also arranged, and shows certain therapeutical effect trend.
The specific embodiment
Further describe the medicine that the present invention treats anemopyretic cold below in conjunction with specific embodiment.
Embodiment 1
The pharmaceutical composition of the treatment anemopyretic cold of present embodiment, it is the medicament of being made by the material medicine of following weight:
80 parts on Folium Mori, 40 parts of Flos Chrysanthemis, 18 parts of Herba Menthaes, 30 parts of Radix Bupleuri, 24 parts of Rhizoma Phragmitiss, 24 parts of Radix Isatidis, 20 parts of Flos Loniceraes, 10 parts of Fructus Forsythiaes, 20 parts in Herba Spirodelae, Radix Saposhnikoviae 20,20 parts in Semen Armeniacae Amarum, 9 parts in Radix Glycyrrhizae.
The Chinese medicine composition of the described treatment anemopyretic cold of present embodiment is prepared in accordance with the following methods:
(1) weighting raw materials thing is by weight ratio pulverized together, crosses 80 mesh sieves, with 60% soak with ethanol of 5 times of injection volumes 30 minutes, and reflux, extract, effective ingredient 3 times, each 1 hour, merge extractive liquid,, filtration;
(2) step (1) effective ingredient of carrying is merged, adds starch, dextrin is made graininess, through screening, dry to moisture be not more than 9%, sterilization, packing get concentrated pill, the heavy 1g of every 7-8 ball.The instructions of taking of this concentrated pill is: oral, and a 1g, 3 times on the one.
Embodiment 2
The pharmaceutical composition of the treatment anemopyretic cold of present embodiment, it is the medicament of being made by the material medicine of following weight:
Folium Mori 30,35 parts of Flos Chrysanthemis, 15 parts of Herba Menthaes, 25 parts of Radix Bupleuri, 18 parts of Rhizoma Phragmitiss, 18 parts of Radix Isatidis, 12 parts of Flos Loniceraes, 12 parts of Fructus Forsythiaes, 18 parts in Herba Spirodelae, Radix Saposhnikoviae 18,18 parts in Semen Armeniacae Amarum, 7 parts in Radix Glycyrrhizae.
The pharmaceutical composition of the described treatment anemopyretic cold of present embodiment is prepared in accordance with the following methods:
(1) weighting raw materials thing is by weight ratio pulverized together, crosses 100 mesh sieves, with 60% soak with ethanol of 5 times of injection volumes 30 minutes, and reflux, extract, effective ingredient 3 times, each 1 hour, merge extractive liquid,, filtration;
(2) step (1) effective ingredient of carrying is merged, be condensed into thick paste, add starch, dextrin is made tablet, drying to moisture is not more than 9%, sterilization, packing get tablet, and every contains dry extract 0.5g.The instructions of taking of this tablet is: oral, and a 1g, 3 times on the one.
Embodiment 3
The pharmaceutical composition of the treatment anemopyretic cold of present embodiment, it is the medicament of being made by the material medicine of following weight:
45 parts on Folium Mori, 32 parts of Flos Chrysanthemis, 14 parts of Herba Menthaes, 18 parts of Radix Bupleuri, 15 parts of Rhizoma Phragmitiss, 15 parts of Radix Isatidis, 15 parts of Flos Loniceraes, 15 parts of Fructus Forsythiaes, 15 parts in Herba Spirodelae, Radix Saposhnikoviae 15,15 parts in Semen Armeniacae Amarum, 15 parts in Radix Glycyrrhizae.The pharmaceutical composition of the described treatment anemopyretic cold of present embodiment is prepared in accordance with the following methods:
(1) weighting raw materials thing is by weight ratio pulverized together, crosses 120 mesh sieves, with the water logging bubble of 8 times of injection volumes 30 minutes, and reflux, extract, effective ingredient 3 times, each 1 hour, merge extractive liquid,, filtration;
(2) step (1) effective ingredient of carrying is merged, is condensed into thick paste, dry to moisture be not more than 9%, sterilization, fill capsule, packing get capsule, every contains dry extract 0.5g.The instructions of taking of this capsule is: oral, and a 1g, 3 times on the one.

Claims (4)

1. pharmaceutical composition for the treatment of anemopyretic cold, it is the medicament of being made by following bulk drugs thing:
Folium Mori 40-80 part, Flos Chrysanthemi 20-40 part, Herba Menthae 10-18 part, Radix Bupleuri 10-30 part, Rhizoma Phragmitis 10-24 part, Radix Isatidis 10-24 part, Flos Lonicerae 10-20 part, Fructus Forsythiae 10-20 part, Herba Spirodelae 10-20 part, Radix Saposhnikoviae 10-20, Semen Armeniacae Amarum 10-20 part, Radix Glycyrrhizae 3-9 part.
2. the pharmaceutical composition of treatment anemopyretic cold according to claim 1 is characterized in that it is the medicament of being made by following bulk drugs thing:
Folium Mori 30-60 part, Flos Chrysanthemi 30-35 part, Herba Menthae 12-15 part, Radix Bupleuri 12-25 part, Rhizoma Phragmitis 12-18 part, Radix Isatidis 12-18 part, Flos Lonicerae 12-18 part, Fructus Forsythiae 12-18 part, Herba Spirodelae 12-18 part, Radix Saposhnikoviae 12-18, Semen Armeniacae Amarum 12-18 part, Radix Glycyrrhizae 5-7 part.
3. the pharmaceutical composition of treatment anemopyretic cold according to claim 2 is characterized in that it is the medicament of being made by following bulk drugs thing:
45 parts on Folium Mori, 32 parts of Flos Chrysanthemis, 14 parts of Herba Menthaes, 18 parts of Radix Bupleuri, 15 parts of Rhizoma Phragmitiss, 15 parts of Radix Isatidis, 15 parts of Flos Loniceraes, 15 parts of Fructus Forsythiaes, 15 parts in Herba Spirodelae, Radix Saposhnikoviae 15,15 parts in Semen Armeniacae Amarum, 15 parts in Radix Glycyrrhizae.
4. the pharmaceutical composition of treatment anemopyretic cold according to claim 1 is characterized in that described medicament is capsule, pill, electuary or tablet.
CN2009102520014A 2009-12-01 2009-12-01 Medicine combination for treating wind-heat type common cold Pending CN102078525A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102327441A (en) * 2011-09-23 2012-01-25 朱来清 Medicinal preparation for treating cold
CN102550782A (en) * 2012-01-16 2012-07-11 徐州韩氏食品有限公司 Herbaceous cool throat smoothing candy and making method thereof
CN105012377A (en) * 2014-04-28 2015-11-04 匡晔 Plant antibiotic capsule
CN105267718A (en) * 2014-06-26 2016-01-27 济南舜景医药科技有限公司 Cold prevention tea
CN108310299A (en) * 2018-05-11 2018-07-24 耿全好 A kind of Chinese medicine preparation for treating sphagitis
CN108578478A (en) * 2018-07-16 2018-09-28 刘洋 The Lonicera and Forsythia cream and preparation method thereof massaged for children's wind-heat cold

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102327441A (en) * 2011-09-23 2012-01-25 朱来清 Medicinal preparation for treating cold
CN102327441B (en) * 2011-09-23 2013-02-20 朱来清 Medicinal preparation for treating cold
CN102550782A (en) * 2012-01-16 2012-07-11 徐州韩氏食品有限公司 Herbaceous cool throat smoothing candy and making method thereof
CN105012377A (en) * 2014-04-28 2015-11-04 匡晔 Plant antibiotic capsule
CN105267718A (en) * 2014-06-26 2016-01-27 济南舜景医药科技有限公司 Cold prevention tea
CN108310299A (en) * 2018-05-11 2018-07-24 耿全好 A kind of Chinese medicine preparation for treating sphagitis
CN108578478A (en) * 2018-07-16 2018-09-28 刘洋 The Lonicera and Forsythia cream and preparation method thereof massaged for children's wind-heat cold

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Application publication date: 20110601