CN102078441B - Pharmaceutical composition for treating hemiplegia - Google Patents
Pharmaceutical composition for treating hemiplegia Download PDFInfo
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- CN102078441B CN102078441B CN2010105980741A CN201010598074A CN102078441B CN 102078441 B CN102078441 B CN 102078441B CN 2010105980741 A CN2010105980741 A CN 2010105980741A CN 201010598074 A CN201010598074 A CN 201010598074A CN 102078441 B CN102078441 B CN 102078441B
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Abstract
The invention relates to a pharmaceutical composition for treating hemiplegia, which is characterized by comprising the following raw medicines in parts by weight: 5-7 parts of radix angelicae pubescentis, 5-7 parts of mistletoe, 5-7 parts of radix sileris, 5-7 parts of gentiana macrophylla, 8-10 parts of angelica, 3-6 parts of licorice, 7-10 parts of pawpaw, 5-8 parts of Chinese wolfberry, 6-8 parts of teasel root, 5-7 parts of cassia twig, 5-7 parts of radix achyranthis bidentatae, 7-9 parts of radix cyathulae, 3-5 parts of spina gleditsiae and 5-9 parts of pepper. The pharmaceutical composition provided by the invention can take a good effect in a short time after being taken by a patient with acute apoplexy; the pharmaceutical composition provided by the invention has the advantages of small dose and cheap price and can be taken by patients conveniently; and the pharmaceutical composition provided by the invention not only takes an effect on hemiplegia caused by apoplexy involving the channels and collaterals, but also has an obvious effect on treating osseous rheumatism, ostealgia and joint tuberculosis.
Description
(1) technical field
The present invention relates to a kind of pharmaceutical composition, specifically is the pharmaceutical composition that is used to treat hemiplegia.
(2) background technology
Apoplexy is the general designation of Chinese medicine to acute cerebrovascular disease.Doctor trained in Western medicine is divided into the different type of two attributes, i.e. hemorrhagic apoplexy and cerebral infarction again to the explanation of this type disease.Hemorrhagic apoplexy comprises cerebral hemorrhage and subarachnoid hemorrhage, and cerebral infarction comprises cerebral thrombosis, cerebral embolism, lacunar infarction and transient ischemic attack.It is suddenly fainting for an apoplexy, syncope, the distortion of commissure that occurs together, dysphonia and one type of disease that hemiplegia is a cardinal symptom occurs.Because the primary disease sickness rate is high, mortality rate is high, disability rate is high, relapse rate is high and complication is many, so medical circle is listed as its same coronary heart disease, cancer one of three big diseases that threaten human health.
Hemiplegia is that wind apoplex involving the channels and collaterals or wind apoplexy involving FU-organ are dirty through treatment, conscious after, the sequela that stays, like hemiplegia, dysphonia, deviation of the eye and mouth etc. are difficult to for the moment recover, very the person can become lifelong trouble.The morbidity back is acute stage in initial 2 weeks generally speaking, and 2 weeks got into convalescent period later, then were sequela stage more than half a year.Rehabilitation for the hemiplegia sequela has following several kinds: the motor function training of science, acupuncture～massage rehabilitation, Chinese medicine rehabilitation, other methods of rehabilitation.The motor function training of science belongs to rehabilitation medicine, how could realize that in bigger hospital the doctor that can grasp and use is also few in number at present, and the time that needs is also long.Because mostly this sick patient is aged people, after the apoplexy, internal organs are deficient, functional disorder, and with the passing of time pathogenic factor is delaied, the healthy energy consume.And rehabilitation training needs willpower, patience and persistency, and therefore many patients are difficult to adhere to.Acupuncture or massage rehabilitation equally also need be by professional doctor operation, the time that needs equally is long, patient and patient's family members are along with the continuity of time, easy abandoning cure.The Chinese medicine rehabilitation such as the patent No. are that " 200710054777.7 ", name are called the patent application of " century health preserving magical wine "; Wherein not only used such as rare Chinese medicines such as Radix Ginseng, Cornu Cervi Pantotrichums; And dose is big, and to dissimilar patients, the plus-minus of dose should not be grasped.
(3) summary of the invention
The objective of the invention is to, overcome above-mentioned in some defectives that exist aspect the hemiplegia that causes of treatment apoplexy.Carry a kind of altogether pharmaceutical composition that is used to treat hemiplegia.
In order to realize above-mentioned purpose, the present invention is according to following technical scheme.Said composition is made up of following bulk drugs: 5～7 parts of Radix Angelicae Pubescentiss, 5～7 parts of Herba Taxillis, windproof 5～7 parts, 5～7 parts of Radix Gentianae Macrophyllae, 8～10 parts of Radix Angelicae Sinensis, 7～10 parts of Fructus Chaenomeliss, 5～8 parts of Fructus Lyciis, 3～6 parts in Radix Glycyrrhizae, 6～8 parts of Radix Dipsacis, 5～7 parts of Ramulus Cinnamomi, 5～7 parts of Radix Achyranthis Bidentataes, 7～9 parts of Radix Cyathulaes, 3～5 parts of Spina Gleditsiaes, 5～9 parts in red wedge angle Fructus Capsici.
Method for preparing of the present invention be with the above-mentioned raw materials medicine to going in the marmite, adding an amount of decocting of water three times, be divided into three times after the mixing and take.It is better in addition above-mentioned former medicine to be prepared into the medicated wine effect.
Superiority of the present invention is just ability onset at short notice after patients during acute stage is taken in the wind, and effect is good; Dose of the present invention is few, and patient's clothes have conveniently, low price; The present invention is not only to being produced effect by the hemiplegia that causes after the apoplex involving the channels and collaterals type apoplexy, also to the rheumatism bone is swollen, muscles and bones is ached, crane knee joint disease also has very significantly curative effect.
Because the pathogeny of apoplexy has with following factor: 1, basic pathogenesis is an imbalance of YIN and YANG, and QI and blood is disorderly contrary.Sick position is at heart and brain, and is relevant with Liver and kidney.2, pathological factor has void, fire, gas, blood, wind, expectorant six ends.Empty (hepatic and renal YIN deficiency, the deficiency of vital energy); Fire (liver-fire, heart-fire); Expectorant (wind-phlegm, damp-phlegm); Wind (liver-wind); Gas (QI rising in reverse order); Blood (blood stasis) 3, pathology character belong to deficiency in origin and excess in superficiality more.4, histological type is divided apoplex involving the channels and collaterals and middle internal organs.Therefore will start with targetedly from above-mentioned several respects in the treatment.
What the present invention was primarily aimed at is the hemiplegia that causes by after the apoplex involving the channels and collaterals type apoplexy.In the passages through which vital energy circulates person, do not have the six channels exterior syndrome outward, interior no constipation interior syndrome is can not nourishing muscle and tendon a little less than the blood, so brothers can not move, stiff tongue is felt embarrassed to mention, mouthful eye tiltedly should tonifying the blood and stretching the tendon.The medicine that the present invention is used: Radix Angelicae Pubescentis is gone into liver, kidney, urinary bladder channel.Its effect is to dispel the wind, and wins and wets, cold expelling, pain relieving.Cure mainly anemofrigid-damp arthralgia, soreness of waist and knee joint, trick spasm and pain etc., especially with diseases such as the arthralgia pain of bottom, soreness of waist and knee joint, two flaccidity of the lower limbs numbness, joint stuffiness for suitable.Herba Taxilli is gone into liver, kidney, urinary bladder channel.Its effect is invigorating the liver and kidney, bone and muscle strengthening, remove rheumatism, the meridian dredging, beneficial blood.Cure mainly that soreness of waist and knee joint, muscles and bones flaccidity are weak, limbs are hemiplegia, anemofrigid-damp arthralgia etc.Windproofly go into to return bladder, lung, spleen, Liver Channel.Its effect is an expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.Be applicable to anemofrigid-damp arthralgia, arthrodynia of extremities, muscle arteries and veins contraction urgency person.Radix Gentianae Macrophyllae is gone into liver, stomach, gallbladder meridian.Its effect is a wind-damp dispelling; The Shujin network; Clearind deficient heat; The dampness removing jaundice eliminating.Cure mainly the logical pain of rheumatism numbness, the muscles and bones contracture, hands and feet caused by paralysis, joint are ached etc.When being included into liver, the heart, spleen channel.Its effect is to enrich blood to invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be mainly used in all cards of blood deficiency, numbness of the skin, flaccidity syndrome and arthralgia syndrome etc.Fructus Chaenomelis goes into liver, lung, kidney channel, spleen channel.Its effect is a relaxing muscles and tendons and activating QI and blood in the collateral, the stomach function regulating removing dampness.Be mainly used in rheumatic arthralgia, vague aching of limbs, muscle arteries and veins contracture etc.Fructus Lycii goes into liver, kidney, lung meridian.Its effect is nourishing the liver, nourishing kidney, lung moistening.Be mainly used in caused by liver and kidney deficiency, have a dizzy spell, soreness of the waist and knees, remove wind, tonification muscles and bones can benefit be gone into, and removes asthenia etc.Radix Dipsaci is gone into liver, kidney channel.Its effect is invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, continuous folding wound, ends metrorrhagia.Be mainly used in aching pain in waist and back; The podomere flaccidity syndrome and arthralgia syndrome.Ramulus Cinnamomi is gone into bladder, the heart, lung meridian.Its effect is an expelling cold and relieving exterior syndrome; Promoting the flow of QI-blood by warming the meridian.Be mainly used in and control exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention etc.Radix Achyranthis Bidentatae is gone into liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, ignite descending.Its effect is treatment soreness of waist and knee joint, flaccidity and weakness of the lower limbs.Radix Cyathulae goes into liver, kidney two warps.Blood circulation promoting and blood stasis dispelling; Be mainly used in and control cold-damp waist thigh bone pain, the flaccidity of the lower limbs clonic spasm of the muscle, hematuria, mistake is excessive etc.Though ben is that Radix Cyathulae, Radix Achyranthis Bidentatae all are called Radix Achyranthis Bidentatae for two kinds, property should be distinguished with slightly different, and the promoting the circulation of blood arteries and veins is then used the river person, and the bosom person is then used in invigorating the liver and kidney.Fructus Gleditsia thrusts liver, lung meridian.Invigorate blood circulation, dispel the wind.Cure mainly leprosy, inducing vomiting pertinacious phlegm, control pertinacious phlegm etc.
The patient that the present invention treated is from each general hospital patient, mainly comprises the hemiplegia that causes after the apoplex involving the channels and collaterals type apoplexy that the traditional Chinese medical science says.Clinical manifestation mainly contains a side surface part and limb adynamia, dyskinesia or can not move fully; One side numb limbs and tense tendons; One side view field is damaged; Part patient can have aphasis, if can understand others and speak, but oneself can not be expressed; Though or can speak, do not understand the meaning that others speaks, or the two haves both at the same time.
Therapeutic Method: get the compositions of above-mentioned parts by weight, or decocting or wine bubble, a bu is taken for three times.To taking effect in general 7～15 days in acute stage or convalescent patient.Generally need take the patient who is in chronic phase and can take effect in 1～3 month.
Criterion of cure: 10 days is a course of treatment.Wherein cure and be: the patient need not lean on battle fully and can independently walk about, and walks with firm steps, can more clear dialogue, and memory is recovered better, and upper limb is strong, and the hand held object ability strengthens greatly, and life reaches self-care fully.Effectively be: took for 3 courses of treatment: the state of an illness is recovered as before, walks, speaks, obstacle such as affective interaction disappears basically, basically no longer has sequela, can be engaged in simple housework.
Therapeutic outcome: in 376 routine patients, the patient that curative effect can reach healing reaches 75%.Effectively standard reaches 20%.Invalid 5%.The patient's cure rate that is in acute stage can reach about 95%.
Patent of the present invention is also swollen to the rheumatism bone simultaneously, and muscles and bones is ached, and crane knee joint disease has very significantly curative effect.
(4) specific embodiment
A kind of pharmaceutical composition that is used to treat hemiplegia of the present invention; Form by the former medicine of the plant of following portions by weight, wherein 5～7 parts of Radix Angelicae Pubescentiss, 5～7 parts of Herba Taxillis, windproof 5～7 parts, 5～7 parts of Radix Gentianae Macrophyllae, 8～10 parts of Radix Angelicae Sinensis, 3～6 parts in Radix Glycyrrhizae, 7～10 parts of Fructus Chaenomeliss, 5～8 parts of Fructus Lyciis, 6～8 parts of Radix Dipsacis, 5～7 parts of Ramulus Cinnamomi, 5～7 parts of Radix Achyranthis Bidentataes, 7～9 parts of Radix Cyathulaes, 3～5 parts of Spina Gleditsiaes, 5～9 parts in red wedge angle Fructus Capsici.
Wherein can also select 6 parts of Radix Angelicae Pubescentiss, 6 parts of Herba Taxillis, windproof 6 parts, 7 parts of Radix Gentianae Macrophyllae, 9 parts of Radix Angelicae Sinensis, 3 parts in Radix Glycyrrhizae, 8 parts of Fructus Chaenomeliss, 7 parts of Fructus Lyciis, 7 parts of Radix Dipsacis, 6 parts of Ramulus Cinnamomi, 6 parts of Radix Achyranthis Bidentataes, 8 parts of Radix Cyathulaes, 4 parts of Spina Gleditsiaes, 8 parts in red wedge angle Fructus Capsici for use.
The above-mentioned raw materials medicine is placed in the marmite, add an amount of decocting of water three times, mix the back branch and take for three times/day.10 days is a course of treatment.It is better in addition above-mentioned former medicine to be prepared into the medicated wine effect.
Claims (2)
1. pharmaceutical composition that is used to treat hemiplegia is characterized in that being made up of following bulk drugs: 5～7 parts of Radix Angelicae Pubescentiss, 5～7 parts of Herba Taxillis, windproof 5～7 parts, 5～7 parts of Radix Gentianae Macrophyllae, 8～10 parts of Radix Angelicae Sinensis, 3～6 parts in Radix Glycyrrhizae, 7～10 parts of Fructus Chaenomeliss, 5～8 parts of Fructus Lyciis, 6～8 parts of Radix Dipsacis, 5～7 parts of Ramulus Cinnamomi, 5～7 parts of Radix Achyranthis Bidentataes, 7～9 parts of Radix Cyathulaes, 3～5 parts of Spina Gleditsiaes, 5～9 parts in red wedge angle Fructus Capsici.
2. a kind of pharmaceutical composition that is used to treat hemiplegia according to claim 1 is characterized in that being made up of following bulk drugs: 6 parts of Radix Angelicae Pubescentiss, 6 parts of Herba Taxillis, windproof 6 parts, 7 parts of Radix Gentianae Macrophyllae, 9 parts of Radix Angelicae Sinensis, 3 parts in Radix Glycyrrhizae, 8 parts of Fructus Chaenomeliss, 7 parts of Fructus Lyciis, 7 parts of Radix Dipsacis, 6 parts of Ramulus Cinnamomi, 6 parts of Radix Achyranthis Bidentataes, 8 parts of Radix Cyathulaes, 4 parts of Spina Gleditsiaes, 8 parts in red wedge angle Fructus Capsici.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010105980741A CN102078441B (en) | 2010-12-21 | 2010-12-21 | Pharmaceutical composition for treating hemiplegia |
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| CN2010105980741A CN102078441B (en) | 2010-12-21 | 2010-12-21 | Pharmaceutical composition for treating hemiplegia |
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| CN102078441A CN102078441A (en) | 2011-06-01 |
| CN102078441B true CN102078441B (en) | 2012-01-04 |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1182604A (en) * | 1996-11-20 | 1998-05-27 | 甘肃省中医院 | Ointment for treating apoplexy |
| CN1286108A (en) * | 1999-09-01 | 2001-03-07 | 陈大明 | Chinese medicine for treating apoplexy |
| CN1365819A (en) * | 2001-01-16 | 2002-08-28 | 李君� | Medicine for treating apoplexy |
| CN1947790A (en) * | 2006-05-31 | 2007-04-18 | 胡成章 | Medicine for treating paralysis and its prepn. method |
-
2010
- 2010-12-21 CN CN2010105980741A patent/CN102078441B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1182604A (en) * | 1996-11-20 | 1998-05-27 | 甘肃省中医院 | Ointment for treating apoplexy |
| CN1286108A (en) * | 1999-09-01 | 2001-03-07 | 陈大明 | Chinese medicine for treating apoplexy |
| CN1365819A (en) * | 2001-01-16 | 2002-08-28 | 李君� | Medicine for treating apoplexy |
| CN1947790A (en) * | 2006-05-31 | 2007-04-18 | 胡成章 | Medicine for treating paralysis and its prepn. method |
Non-Patent Citations (4)
| Title |
|---|
| 姜坤.中医治疗类风湿关节炎(RA)研究进展.《中国社区医师(综合版)》.2007,第09卷(第08期), * |
| 彭燮.验案两则.《四川中医》.1983,(第06期), * |
| 李谱智.《脾胃论》中风燥升阳药物运用特点.《广西中医药》.1987,(第02期), * |
| 裴秀娥.补益肝肾法治疗中风后遗症.《中国民间疗法》.1996,(第04期), * |
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