CN102058656A - Oral traditional Chinese medicine preparation for treatment of hydrophobia - Google Patents

Oral traditional Chinese medicine preparation for treatment of hydrophobia Download PDF

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Publication number
CN102058656A
CN102058656A CN2009102282798A CN200910228279A CN102058656A CN 102058656 A CN102058656 A CN 102058656A CN 2009102282798 A CN2009102282798 A CN 2009102282798A CN 200910228279 A CN200910228279 A CN 200910228279A CN 102058656 A CN102058656 A CN 102058656A
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China
Prior art keywords
mylabris
treatment
traditional chinese
chinese medicine
hydrophobia
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CN2009102282798A
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Chinese (zh)
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范培柱
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TIANJIN BIJIA PHARMACEUTICAL GROUP CO Ltd
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TIANJIN BIJIA PHARMACEUTICAL GROUP CO Ltd
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Priority to CN2009102282798A priority Critical patent/CN102058656A/en
Publication of CN102058656A publication Critical patent/CN102058656A/en
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Abstract

The invention discloses an oral traditional Chinese medicine preparation for the treatment of hydrophobia, which is prepared from 0.5 to 1g septemlobate kalopanax root, 0.5 to 0.7g honeysuckle, 0.5 to 0.7g liquorice and 0.2 to 0.8g mylabris. The preparation method comprises the following steps: decocting the mylabris, then grinding to powder, sieving, and mixing the powder with other traditional Chinese medicines to prepare various oral preparations. As proved by clinical practices, the oral traditional Chinese medicine preparation has a remarkable effect on hydrophobia with the effective rate up to 90%. The traditional Chinese medicine for the prevention and treatment of hydrophobia provided by the invention contains the ingredients with moderate nature and small toxicity. The actual application effect is extremely satisfactory.

Description

The rabic oral preparation of Chinese traditional medicinal of a kind of treatment
Technical field
The invention belongs to the Chinese medicine preparation technical field, relate to the rabic oral preparation of Chinese traditional medicinal of treatment, say so more specifically rabic Chinese medicinal capsule of a kind of treatment or tablet.
Background technology
In recent years, not enough to popularizing of rabies preventive treatment knowledge in addition along with supporting increasing and lacking strict control of Canis familiaris L. and domestic pets quantity to house pets such as dog and cats, make the rise in continuous 5 years of China's rabies sickness rate.According to the Ministry of Public Health statistics, occupy first of all kinds of infectious disease to rabies case fatality rate in 2003.The fact in the face of this sternness, should give full play to the intervention effect of nurse in prevention work, from community to clinical, need integrate propagandist, urger, consultant, at high-risk group and the foster big rural area of dog density, carry out the prevention propaganda, popularize rabic preventive treatment knowledge, reduce rabic sickness rate.Because being in rabies, China continues the stage occurred frequently of rising, healthy animal band poison has become the serious hidden danger of ours at one's side, so threatening human life security and health. after being bitten by animal, it is to take precautions against rabies requisite three big steps that wound, injecting immune serum and vaccination are handled in flushing in time.Five pin therapies are usually adopted in rabies immune vaccination, and the immunity time is zero, three, seven, 14,28 days.Seriously injured person also need inject rabies antiserum or rabies immune globulin before vaccination.
Ancients have had preliminary understanding to rabies very early, but that make a breakthrough aspect preventing and treating in rabies is the modern science man, and wherein the contribution of being done with French microbiologist's Pasteur especially is in the majority.Pasteur finds that the aerial oxidization time of pathogenic bacteria is long more, and toxicity will be weak more.If the pathogenic bacteria behind the perform toxic attenuation is placed on the environment that helps their growths, in the humans and animals body, they can be bred again once again in a large number.But, the pathogenic bacteria toxicity of breeding out in this case is very weak, is not enough to fatally, can stimulate intravital immuning system generating antibody on the contrary, reaches the effect of immunity, " artificial attenuation method " (being called artificial immunization afterwards) of Here it is Pasteur.The people that significant proportion arranged at present not by the specification handles wound, does not inoculate rabies vaccine after being stung, scratch by dog.Investigation of Jiangsu Prov. Disease Preventing and Controlling Center shows, in 59 routine rabies humans, carries out 33 examples of having only of treatment of wounds after injured, accounts for 55.93%.The expert reminds, citizen in case by animal bites such as Canis familiaris L., cats, scratch, can't deposit any lucky heart, be in time to section hospital's wound that cleans and sterilize, be preferably in to inoculate rabies vaccine in 24 hours or add and use antiserum; During epidemic prevention, also can not act on one's own, reduce the inferior and administrated method of medication pin, otherwise can lead to disastrous effect.
Summary of the invention
The objective of the invention is to, overcome above-mentioned shortcoming with not enough, provide a kind of cheap, method is simple, the rabic Chinese medicine secret prescription handed down in the family from generation to generation of treatment evident in efficacy.
The inventor is engaged in rabic Chinese medicine development work for many years, a large amount of Chinese medicines have been read about treating rabic books, but how can from numerous medical materials, filter out the medical material of therapeutic effect, how the medical material that screens is made up, how selecting reasonable proportioning is arduous, a careful job.The inventor gropes to be surprised to find through secular test: with a certain amount of root of Semen Caesalpiniae, Flos Lonicerae, Radix Glycyrrhizae, Mylabris mixes has peculiar curative effect to the treatment rabies, the inventor has carried out a large amount of trial tests for this reason, guaranteeing under the prerequisite of curative effect that the further perfect proportioning of four flavor Chinese medicines has been finished experiment work of the present invention finally.
Technical scheme of the present invention is as follows:
The rabic oral preparation of Chinese traditional medicinal of a kind of treatment is characterized in that said preparation by root of Semen Caesalpiniae, Flos Lonicerae, and Radix Glycyrrhizae, Mylabris is formulated, and each component raw material weight proportion is as follows:
Root of Semen Caesalpiniae 0.5-1g, Flos Lonicerae 0.5-0.7g, Radix Glycyrrhizae 0.5-0.7g, Mylabris 0.2-0.8g.
Oral preparation of Chinese traditional medicinal of the present invention refers to: tablet, capsule or pill.
The preparation method of oral preparation of Chinese traditional medicinal of the present invention is: Mylabris is fried in shallow oil dry grinding, sieve then and other medical material mix homogeneously, incapsulate; The Mel mf mass pil that maybe will mix back medical material and 3-5%; Or the starch ethanol solution that adds 30-50% is made tablet.
The present invention treats rabic oral preparation of Chinese traditional medicinal, has to form simply, and taking convenience, the curative effect height, raw material is easy to get, lower-price characteristic.Take through 1000 many cases patients, clinical practice proves: effective percentage reaches 100%, and cure rate reaches 100%.Cured thousands of routine hydrophobes for many years, none example is dead.
Rabies oral preparation of Chinese traditional medicinal of the present invention (capsule or pill), the patient both can take immediately, also can in 5-7, take, but can not surpass 7 days the latest, this medicine is once taking, and effect is obvious, behind the transference cure, method is particularly suitable for the patient by dog bite no longer again, leaks the injection rabies vaccine but surpass 7 days patient to take.
Tablet of the present invention, capsule or pill are generally taken by the dosage of a course of treatment.The dosage of a described course of treatment (potion just) refers to tablet, pill, the capsule that the disclosed composition of embodiment 1-8 and proportioning are made.Special situation can suitable being regulated according to patient's the state of an illness.What this need be illustrated especially again is, because oral preparation of Chinese traditional medicinal of the present invention has certain toxicity, so anemia of pregnant woman's forbidding, heart disease, nephrotic's forbidding.
Take the actual effect that the present invention treats rabic Chinese medicine preparation in order more clearly to illustrate, existing with the in addition detailed description of typical actual case.
In May, (1) 2000, live the Sun Xiaobao in Shuangcheng City money village, boy 15 years old plays in the village because of carelessness by the right lower limb of dog bite, do not mind at that time, found to occur the patient having a fever in the 3rd day 38 ℃, appetite disappear, headache, symptom such as feel sick, take this capsule after the prescription on individual diagnosis, divide 3 clothes down with dose, patient's readme has slight stomachache sense; the urine number of times significantly increases, and the transference cure of discomfort is followed up a case by regular visits to and do not seen recurrence after 2 days.
In January, (2) 2003, live the Zhao Xiaohua that the core village is educated in the Changchun, woman 45 years old, in the village,, do not mind at that time, found in the 4th day that chest pain, wind can cause the bottleneck throat muscle spasm when facial by the dog bite left hand, wound location has pain, keep in dark place, be afraid of noise, be afraid of drinking-water, hyperhidrosis, take this potion (incapsulating) after the prescription on individual diagnosis, patient's readme has slight stomachache sense; the urine number of times significantly increases, and has the blood streak, accidental clot in the urine, the pain relief of wound location after 2 days.Add half agent according to the state of an illness, symptom complete obiteration after 3 days is followed up a case by regular visits to and is not seen recurrence.
In August, (3) 2004, live the Liang Suofang in Shuangcheng City money village, woman 70 years old, in the village,, only handled wound at that time, and found fever, tired uneasiness in the 6th day, be snapped position pain with local method by dog bite left side lower limb, keep in dark place, the bottleneck throat spasm is taken this potion (incapsulating) after the prescription on individual diagnosis, dose is divided 3 clothes down at every turn, patient's readme has slight stomachache sense; the urine number of times significantly increases, and has clot in the urine, and the posterior phraynx laryngeal spasm obviously alleviated in 2 days.Add potion again according to the state of an illness, readme urine increased frequency has the bubble end in the urine, and symptom complete obiteration after 3 days is followed up a case by regular visits to and do not seen recurrence.
In October, (4) 2005,3 pupils of Shuangcheng City unity township money primary school, when break, very do not scratched by the Canis familiaris L. in the school, wherein one by dog bite, there was not the rabies vaccine entry needle at that time, all taken Chinese medicine preparation of the present invention (capsule) potion, in the date afterwards, do not seen that malaise symptoms appears in a student.
The present invention treats rabic oral preparation of Chinese traditional medicinal, has used for many years, has successively cured 1000 many cases hydrophobes, and none example is dead.Most of patient's symptom characteristic is consistent basically, within 5-7 days, after taking this medicine, can prove at once whether this Canis familiaris L. carries the rabies vaccine pathogenic bacteria after by dog bite.If after being carried the dog bite of pathogenic bacteria, taking this medicine in 5-7 days has slight stomachache, and it is diligent urine to occur, and urine retention has the blood streak in the urine, has clot in the severe patient urine.If, take this medicine, as normal, can not damage human body without any reaction by behind the common dog bite.
What need be illustrated especially is that oral preparation of Chinese traditional medicinal of the present invention needs to take in by the 5-7 of dog bite days, and the side effectively can not take this medicine if surpass 7 days again.
The specific embodiment:
The following examples can help those skilled in the art more fully to understand the present invention.But do not limit the present invention in any way.
Embodiment 1
Root of Semen Caesalpiniae 0.5g, Flos Lonicerae 0.5g, Radix Glycyrrhizae 0.5g, Mylabris 0.7g (southern mylabris phalerata).Mylabris is fried in shallow oil dry grinding, sieve then and other medical material mix homogeneously, incapsulate, form potion.
Embodiment 2
Root of Semen Caesalpiniae 1g, Flos Lonicerae 0.5g, Radix Glycyrrhizae 0.8g, Mylabris (yellow black mylabris cichorii) 0.7g fries in shallow oil dry grinding with Mylabris, sieves then and other medical material mix homogeneously, adds 5% Mel then and makes pill, forms potion.
Embodiment 3
Root of Semen Caesalpiniae 1g, Flos Lonicerae 0.5g, Radix Glycyrrhizae 0.3g, Mylabris (southern mylabris phalerata) 0.5g.Mylabris is fried in shallow oil dry grinding, sieve then and other medical material mix homogeneously, add amylum pregelatinisatum 10g, dextrin 2.5g, microcrystalline Cellulose 2g, magnesium stearate 2.5g, mix homogeneously, 40% ethanol pelletize, tabletting, bag film-coat.
Embodiment 4
Root of Semen Caesalpiniae 0.5g, Flos Lonicerae 0.7g, Radix Glycyrrhizae 0.8g, Mylabris (yellow black mylabris cichorii) 0.2g.Mylabris is fried in shallow oil dry grinding, sieve then and other medical material mix homogeneously, incapsulate, form potion.
Embodiment 5
Root of Semen Caesalpiniae 1g, Flos Lonicerae 0.7g, Radix Glycyrrhizae 0.3g, Mylabris (southern mylabris phalerata) 0.5g.Mylabris is fried in shallow oil dry grinding, sieve then and other medical material mix homogeneously, incapsulate, form potion.
Embodiment 6
Root of Semen Caesalpiniae 0.7g, Flos Lonicerae 0.5g, Radix Glycyrrhizae 0.8g, Mylabris (yellow black mylabris cichorii) 0.5g.Mylabris is fried in shallow oil dry grinding, sieve then and other medical material mix homogeneously, incapsulate, form potion.
Embodiment 7
Root of Semen Caesalpiniae 1g, Flos Lonicerae 0.5g, Radix Glycyrrhizae 0.5g, Mylabris (yellow black mylabris cichorii) 0.2g.Mylabris is fried in shallow oil dry grinding, sieve then and other medical material mix homogeneously, incapsulate, form potion.
Embodiment 8
Root of Semen Caesalpiniae 0.5g, Flos Lonicerae 0.7g, Radix Glycyrrhizae 0.5g, Mylabris (southern mylabris phalerata) 0.3g.Mylabris is fried in shallow oil dry grinding, sieve then and other medical material mix homogeneously, add amylum pregelatinisatum 3g, magnesium stearate 2.5g, mix homogeneously, 40% ethanol pelletize, tabletting bag film-coat.

Claims (3)

1. the rabic oral preparation of Chinese traditional medicinal of treatment is characterized in that said preparation by root of Semen Caesalpiniae, Flos Lonicerae, and Radix Glycyrrhizae, Mylabris is formulated, and each component raw material weight proportion is as follows:
Root of Semen Caesalpiniae 0.5-1g, Flos Lonicerae 0.5-0.7g, Radix Glycyrrhizae 0.5-0.7g, Mylabris 0.2-0.8g.
2. the described oral preparation of Chinese traditional medicinal of claim 1, preparation wherein is tablet, capsule or pill.
3. method for preparing claim 1 or 2 described oral preparation of Chinese traditional medicinal is characterized in that: Mylabris is fried in shallow oil dry grinding, sieve then and other medical material mix homogeneously, incapsulate; The Mel mf mass pil that maybe will mix back medical material and 3-5%; Or the starch ethanol solution that adds 30-50% is made tablet.
CN2009102282798A 2009-11-16 2009-11-16 Oral traditional Chinese medicine preparation for treatment of hydrophobia Pending CN102058656A (en)

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Application Number Priority Date Filing Date Title
CN2009102282798A CN102058656A (en) 2009-11-16 2009-11-16 Oral traditional Chinese medicine preparation for treatment of hydrophobia

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Application Number Priority Date Filing Date Title
CN2009102282798A CN102058656A (en) 2009-11-16 2009-11-16 Oral traditional Chinese medicine preparation for treatment of hydrophobia

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CN102058656A true CN102058656A (en) 2011-05-18

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104367785A (en) * 2014-04-29 2015-02-25 宁同喜 Medicine treating rabies

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104367785A (en) * 2014-04-29 2015-02-25 宁同喜 Medicine treating rabies

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Application publication date: 20110518