CN102048839A - External Chinese medicinal preparation for treating scald and burn and preparation method thereof - Google Patents

External Chinese medicinal preparation for treating scald and burn and preparation method thereof Download PDF

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Publication number
CN102048839A
CN102048839A CN2009100711869A CN200910071186A CN102048839A CN 102048839 A CN102048839 A CN 102048839A CN 2009100711869 A CN2009100711869 A CN 2009100711869A CN 200910071186 A CN200910071186 A CN 200910071186A CN 102048839 A CN102048839 A CN 102048839A
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burn
radix
borax
parts
carapax
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CN2009100711869A
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宋德成
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Tianjin Pacific Pharmaceutical Co Ltd
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Tianjin Pacific Pharmaceutical Co Ltd
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Priority to CN2009100711869A priority Critical patent/CN102048839A/en
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Abstract

The invention relates to an external Chinese medicinal preparation for treating scald and burn and a preparation method thereof. The preparation consists of the following components in part by weight: 1 to 50 parts of tortoise plastron, 1 to 20 parts of Chinese coriaria root bark, 0.3 to 5 parts of rhubarb, 0.1 to 3 parts of amur corktree bark, 0.05 to 2 parts of borax, 0.1 to 2 parts of sesame husk and 1 to 30 parts of chestnut leaf. Compared with medicines of the same kind, the external Chinese medicinal preparation (plaster or paste) has quick response, is short in treatment course, does not have any toxic or side effect, is not required to be changed for patients with slight scald and burn, has an anti-infection effect, ensures that scars cannot be left after the scald and the burn are cured, can promote the growth of new skin, and has the effects of eliminating putridity and engendering flesh.

Description

A kind of Chinese medicine for outer use for the treatment of scald, burn and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, relate to Chinese medicine for outer use that is used for the treatment of scald, burn and preparation method thereof, in particular, is that a kind of quick treatment handed down from one's ancestors is scalded, the external cataplasm of tcm or the unguentum of burn.
Background technology
In actual life through regular meeting take place because of because of carelessness by boiled water or steam scald, by the situation of fire burn;, foaming red and swollen rapidly this moment on the surface of skin; serious skin festers; usually pain is unbearably in wounded body; treat untimely meeting and cause skin infection; cause various inflammation, tend on skin, form the crust trace.The wound surface early treatment as hereinbefore, the treatment principle of liquefaction phase is the pharmacological action that tincture is scalded in performance, makes downright bad epithelium connective tissue recover gradually, regenerate, after this this class roughly after wound 7-16 days enters the wound repair phase.At this moment wound surface substrate is uniform ruddy color; in the environment of the protecting film of scalding tincture formation; the newborn epithelial tissue that epidermal stem cells duplicated that in-situ regeneration is new; at this moment to pay special attention to keep wound surface to have medicine to supply with all the time; and the translucent fiber isolating membrane of the one deck that forms on the protection wound surface; the dry pressure dressing etc. that adopts is must guard against in not damage.As covering the formation dry crusts because of lacking the medicine film, then wound surface is dark red, aubergine, even the restock medicine is also deepened the wound surface damage unavoidably, causes treatment time to prolong and the formation cicatrix.Wound healing is ruddy color in early days, a little more than surface, at this moment enters the convalescence treatment; should continue outer spray and scald tincture; at this moment the regenerative healing of wound surface is based on skin corium, and epidermal area does not also have the holomorphosis reparation, still need replace epidermis function and protecting wound surface to scald the tincture film.Pass through left and right sides epidermal layer cells ability holomorphosis reparation in about 16 days again, left and right sides keratinization of epidermis basically formed in 25 days.Behind wound healing, occur being dispersed in or intensive white point on most patient's wound surface, this is the regenerated performance of sebaceous gland, because in scalding the film formed physiological environment of tincture, epithelial tissue and adnexa not degree can in-situ regeneration and reparation, and the reproduction speed of sebaceous gland will be later than epithelial tissue and collagen tissue.The recovery explanation of sebaceous gland, sweat gland function is used the treatment of scalding tincture and is produced a desired effect.If the wound surface of healing does not have sebaceous gland to occur fully, illustrate that the degree of depth of burn has reached whole damages of holostrome skin.
Epidermis dermis is organized holostrome liquefaction coagulation necrosis, forms wax or brown eschar, and palpation adds leather firmly, and is nonelastic, and skin temperature is low, hypalgesia or disappearance.
Shallow III degree most of subcutaneus adipose tissue of burning remains work, need to implement early " the skin ploughing and weeding subtracts an art ", use special ploughing and weeding cutter on wound surface, to make the cut that spacing and the degree of depth are 1mm, no ploughing and weeding cutter can replace with knife blade or roller bearing blade, purpose is to make the decompression of loosening of downright bad epithelial tissue, thereby make the circulation of veins beneath the skin network recovery, the drug effect of the inner performance of the wound surface of infiltration as early as possible of favourable scald tincture simultaneously. above wound surface is handled more early good more, in wound is after back 6 hours is Best Times, then not ideal as surpassing 24 hours curative effects, epithelial tissue tension force after subtracting obviously reduces, change into from pale leather sample and to show slightly ruddy, softness also has a small amount of what is said or talked about red liquid to ooze out, can carry out decompression treatment at 24 hours repeatedly with interior, up to wound surface have ooze out till.Patient does not need anesthesia when implementing above surgical procedure, and feels pain not, illustrates then that if any pain wound surface is the II degree.The wound surface of epidermis and the damage of corium holostrome generally can reach the physiological Regeneration and Repair through the treatment of scalding tincture, its histological basis be remain in sweat gland epithelium basal cell in the subcutaneus adipose tissue, fat every in undifferentiated mesenchymal cell etc. scalding and starting, activating stem cell under the tincture effect, make the new epithelial cell of in-situ regeneration and reach the effect of wound repairing.
The clinical use of Shao Shang Chinese medicine in recent years is extensive, dosage form is abundant, the development of leap has been arranged after the length that has absorbed doctor trained in Western medicine and modern science and technology, but the Chinese medicine burn still needs to solve following several problems: the clinical report that (1) is repeated, level is lower is many, cause the waste of human and material resources, how on higher technical merit, to carry out the quantification unification of traditional Chinese medical science medication and dosage form and still wait to study.(2) the Chinese medicine advantage still in, burn below the small size II °, how under the auxiliary treatment of Western medicine, treatment to serious burn has breakthrough, be still and treat research topic. (3) Chinese medicine determination of active ingredients, especially the action component of compound recipe, these need combining closely of tradition and modernity science and technology just to be expected to break through, and still there is the difficult problem on technology and the method in the research of this respect at present.(4) treatment by Chinese herbs burn evaluation criteria clinical and experimental effect is formulated and standard, this is the basis of reasonable assessment drug effect, because the disunity of standard causes many researchs repeatable poor, also have most reports to rest on experienced case summary, difficult architectonical at present; The MEBT that China medical science man Xu Rongxiang professor founded in the eighties in 20th century, to create burn wound's physiology moist environment, the burn slough is got rid of in liquefaction with no damage, activate potency regeneration cell and be converted into stem cell, provide the stem cells hyperplasia division required life fertile absorber and nutritional labeling, realize the physiological Regeneration and Repair of burn trauma wound surface at last by stem cell new life's histiocytic connection, along with going deep into of research, not only realized the in-situ regeneration of skin organ in burn wound, the while is at the in-situ regeneration (severed finger regeneration) of other many histoorgans, create infections class disease and in the treatment of malignant tumor, also obtained gratifying progress.MBT/MEBO is the revolution of a field technology in burn treating field.
Summary of the invention
The invention discloses a kind of Chinese medicine for outer use that is used for the treatment of scald, burn and preparation method thereof.
Prescription disclosed in this invention is thing handed down from one's ancestors for many years, for repaying society, this side is contributed to society, for the patient who scalds, burn provides more Therapeutic Method of a kind of curative effect.
The present invention is pure Chinese medicine preparation, and it is made up of Carapax et Plastrum Testudinis, Coriaria sinica root bark, Radix Et Rhizoma Rhei, Borax, Pericarpium Sesami indici, chestnut leaves.
Wherein the ratio of weight and number of each Chinese crude drug is:
Carapax et Plastrum Testudinis 1-50 part, Coriaria sinica root bark 1-20 part, Radix Et Rhizoma Rhei 0.3-5 part, Cortex Phellodendri 0.1-3 part, Borax 0.05-2 part, Pericarpium Sesami indici 0.1-2 part, chestnut leaves 1-30 part.
Comparatively preferred Chinese medicine preparation consists of:
Carapax et Plastrum Testudinis 1-25 part, Coriaria sinica root bark 1.5-15 part, Radix Et Rhizoma Rhei 0.3-2.5 part, Cortex Phellodendri 0.1-1.5 part, Borax 0.25-1 part, Pericarpium Sesami indici 0.5-1.5 part, chestnut leaves 5-30 part.
More preferred Chinese medicine preparation consists of:
Carapax et Plastrum Testudinis 1-5 part, Coriaria sinica root bark 2.5-8 part, Radix Et Rhizoma Rhei 0.3-0.5 part, Cortex Phellodendri 0.1-0.3 part, Borax 0.5-1 part, Pericarpium Sesami indici 0.5-1 part, chestnut leaves 10-30 part.
Best Chinese medicine preparation consists of:
3 parts of Carapax et Plastrum Testudiniss, 8 parts of Coriaria sinica root bark, 0.5 part of Radix Et Rhizoma Rhei, 0.3 part of Cortex Phellodendri, 0.5 part of Borax, 0.5 part of Pericarpium Sesami indici, 3 parts of chestnut leaves.
Chinese medicine preparation of the present invention is unguentum or paste, and it prepares preparation method, carries out as follows:
(1) respectively Carapax et Plastrum Testudinis, Coriaria sinica root bark, Radix Et Rhizoma Rhei, Borax, Pericarpium Sesami indici are done stir-fry, grind to form fine powder, it is standby to cross 200 mesh sieves.
(2) take by weighing Carapax et Plastrum Testudinis, Coriaria sinica root bark, Radix Et Rhizoma Rhei, Borax, Pericarpium Sesami indici according to the above ratio, mix homogeneously adds a certain amount of chestnut leaves, fries in shallow oil to stir in 10-60 minute and makes unguentum or paste.
The principles of formulating prescriptions of Chinese medicine for outer use of the present invention are: reducing swelling and alleviating pain, and removing the necrotic tissue and promoting granulation, blood circulation promoting and blood stasis dispelling pulls out dried removing dampness, arresting hemostasia and suppuration, more the back does not have the crust trace.
Selected Radix Et Rhizoma Rhei nature and flavor hardship among the present invention, cold.Has purging heat and dredging bowels, the effect of removing pathogenic heat from blood and toxic substance from the body, external treatment burn due to hot liquid or fire.Wherein selected Radix Et Rhizoma Rhei comprises Radix Et Rhizoma Rhei or Radix Et Rhizoma Rhei, and experimentation shows that Radix Et Rhizoma Rhei has antibacterial action, and is all effective to gram-positive bacterium and some gram negative bacteria.
Burn and scald: Radix Et Rhizoma Rhei, grind to the powder, Ovum Gallus domesticus album is transferred and is applied, or the vinegar accent is deposited still better altogether with Oleum Verniciae fordii Mel.(ten thousand sick proved recipes, secretly hand down odd-prescription) burn and scald: the Coriaria sinica root bark, remove rough bark, levigation is transferred and is applied, and inferior water from washing rice washing morning is applied again.(Shaanxi Chinese herbal medicine) burn and scald: Pericarpium Sesami indici, the ashing sustainability is ground into powder, dried spread or Oleum Sesami is transferred and to be put on the skin.(Yang Chunhuai is through proved recipe) burn: chestnut leaves, decocting cools, and uses the foliar application affected part, soup leaves moisting pain relieving, speed is more.
The Chinese medicine for outer use that the present invention scalds, burns with existing treatment is compared, and has following remarkable result:
1. Chinese medicine for outer use of the present invention (unguentum or paste) is compared instant effect with similar medicine, and curative effect is short, has no side effect.Patient for slight scald, burn need not change dressings, and the anti-infective effect is arranged, and does not stay the crust trace after the healing, can promote the growth of new skin, and the effect of removing the necrotic tissue and promoting granulation is arranged.This prescription is the secret recipe of passing on from generation to generation, and has cured countless cases, and is evident in efficacy.
2. Chinese crude drug wide material sources of the present invention, low price, the preparation method simple possible is easy to promote.
Below by concrete for many years clinical experiment data, further instruction in addition:
Externally used paste of the present invention or paste had carried out the clinical practice in 1 year once in County Hospital, community hospital, treat patient's 100 examples altogether, boiling water burn 40 examples wherein, and steam is scalded 20 examples, burn 40 examples of the damage of skin and pain of flesh that the fire combustion is caused.
Patient for slight scald (mainly be meant and do not get blister) directly is applied to the affected part with pasty medicament, can play alleviating pain, the purpose that disease controlling further worsens.
For the patient who scalds (getting blister), blister surface dead bark is removed back (noting sterilization) ointment is spread upon the affected part uniformly, bear pods in general 24 hours, under the state that keeps dry in the affected part, can fully recover in general 3-5 days.
Therapeutic effect: this medicine was once cured hundreds of people, and overall therapeutic effect is very good, and cure rate reaches 95%, and effective percentage reaches 100%.Its model case is taken passages as follows earlier:
Case is selected:
Open * *, the woman, 18 years old, scald left arm because of pressure cooker steam, red swelling of the skin, pain apply this unguentum unbearably, and skin pain disappears, and scalds left arm after 3 days and recovers fully normally not stay any vestige on the skin.
The king * *, the man, because treatment is untimely, festering had appearred in skin, applied this medicine 3 times because of flame burn in 30 years old, and wound surface is existing to be repaired, and the skin of visible new growth was fully recovered in 7 days, did not see and left the crust trace.
Single * *, the man, 22 years old, scald because of boiled water, get blister, blister surface dead bark is removed back (noting sterilization) ointment is spread upon the affected part uniformly, bear pods in 24 hours, under the state that keeps dry in the affected part, i.e. recovery from illness in 3 days.
Recklessly * *, the woman, 48 years old, scald because of oil, get blister, festering appears in the part, after blister surface dead bark is removed, ointment is spread upon the affected part uniformly, bear pods in 24 hours, under the state that keeps dry in the affected part, i.e. recovery from illness in 5 days.
The specific embodiment
Following examples are with helping understand the present invention, and are not used in and also should be interpreted as the restriction to inventing in the listed claim by any way.The method preparation that wherein raw material can reference example or buying on the market.
Embodiment 1
With Carapax et Plastrum Testudinis 10g, Coriaria sinica root bark 4g, Radix Et Rhizoma Rhei 2g, Cortex Phellodendri 0.5g, Borax 0.25g, Pericarpium Sesami indici 0.5g part grinds to form fine powder, crosses 200 mesh sieves respectively, and mix homogeneously adds chestnut leaves 20g then, fries in shallow oil to stir in 60 minutes and makes unguentum.
Embodiment 2
With Carapax et Plastrum Testudinis 30g, Coriaria sinica root bark 10g, Radix Et Rhizoma Rhei 5g, Cortex Phellodendri 0.3g, Borax 0.25g, Pericarpium Sesami indici 1g part grinds to form fine powder, crosses 200 mesh sieves respectively, and mix homogeneously adds chestnut leaves 30g then, fries in shallow oil to stir in 30 minutes and makes paste.
Embodiment 3
With Carapax et Plastrum Testudinis 25g, Coriaria sinica root bark 15g, Radix Et Rhizoma Rhei 0.5g, Cortex Phellodendri 1.5g, Borax 0.25g, Pericarpium Sesami indici 0.5g part grinds to form fine powder, crosses 200 mesh sieves respectively, and mix homogeneously adds chestnut leaves 20g then, fries in shallow oil to stir in 50 minutes and makes unguentum.
Embodiment 4
With Carapax et Plastrum Testudinis 3g, Coriaria sinica root bark 8g, Radix Et Rhizoma Rhei 0.5g, Cortex Phellodendri 0.3g, Borax 0.5g, Pericarpium Sesami indici 0.5g part grinds to form fine powder, crosses 200 mesh sieves respectively, and mix homogeneously adds chestnut leaves 3g then, fries in shallow oil to stir in 40 minutes and makes paste.

Claims (6)

  1. One kind treat scald, the burn Chinese medicine for outer use, it is made up of Carapax et Plastrum Testudinis, Coriaria sinica root bark, Radix Et Rhizoma Rhei, Borax, Pericarpium Sesami indici, chestnut leaves, its weight consists of Carapax et Plastrum Testudinis 1-50 part, Coriaria sinica root bark 1-20 part, Radix Et Rhizoma Rhei 0.3-5 part, Cortex Phellodendri 0.1-3 part, Borax 0.05-2 part, Pericarpium Sesami indici 0.1-2 part, chestnut leaves 1-30 part.
  2. 2. Chinese medicine for outer use as claimed in claim 1 is characterized in that its weight consists of Carapax et Plastrum Testudinis 1-25 part, Coriaria sinica root bark 1.5-15 part, Radix Et Rhizoma Rhei 0.3-2.5 part, Cortex Phellodendri 0.1-1.5 part, Borax 0.25-1 part, Pericarpium Sesami indici 0.5-1.5 part, chestnut leaves 5-30 part.
  3. 3. Chinese medicine for outer use as claimed in claim 1 is characterized in that its weight composition Carapax et Plastrum Testudinis 1-5 part, Coriaria sinica root bark 2.5-8 part, Radix Et Rhizoma Rhei 0.3-0.5 part, Cortex Phellodendri 0.1-0.3 part, Borax 0.5-1 part, Pericarpium Sesami indici 0.5-1 part, chestnut leaves 10-30 part.
  4. 4. Chinese medicine for outer use as claimed in claim 1 is characterized in that its weight composition: 3 parts of Carapax et Plastrum Testudiniss, 8 parts of Coriaria sinica root bark, 0.5 part of Radix Et Rhizoma Rhei, 0.3 part of Cortex Phellodendri, 0.5 part of Borax, 0.5 part of Pericarpium Sesami indici, 3 parts of chestnut leaves.
  5. 5. as the described Chinese medicine for outer use of claim 1-4, it is characterized in that described Chinese medicine preparation is unguentum or paste.
  6. The defined treatment of claim 1 scald, the preparation method of the Chinese medicine for outer use of burn, carry out as follows: (1) is done Carapax et Plastrum Testudinis, Coriaria sinica root bark, Radix Et Rhizoma Rhei, Borax, Pericarpium Sesami indici respectively and is fried, and grinds to form fine powder, and it is standby to cross 200 mesh sieves; (2) take by weighing Carapax et Plastrum Testudinis, Coriaria sinica root bark, Radix Et Rhizoma Rhei, Borax, Pericarpium Sesami indici according to the above ratio, mix homogeneously adds a certain amount of chestnut leaves, fries in shallow oil to stir in 10-60 minute and makes unguentum or paste.
CN2009100711869A 2009-11-05 2009-11-05 External Chinese medicinal preparation for treating scald and burn and preparation method thereof Pending CN102048839A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019080114A1 (en) * 2017-10-27 2019-05-02 江苏奇力康皮肤药业有限公司 Tcm patch for softening scars

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019080114A1 (en) * 2017-10-27 2019-05-02 江苏奇力康皮肤药业有限公司 Tcm patch for softening scars

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Application publication date: 20110511