CN102048224A - Red jujube health-care beverage capable of removing chloasma, beautifying features and improving skin, and production technology thereof - Google Patents
Red jujube health-care beverage capable of removing chloasma, beautifying features and improving skin, and production technology thereof Download PDFInfo
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Abstract
The invention relates to a red jujube health-care beverage, which can remove chloasma, beautify features and improve skin, and also relates to the production technology thereof. The invention combines the traditional Chinese medical science theory and the modern science theory, uses natural Chinese herbal medicine like red jujube as the main raw material, and prepares the red jujube health-care beverage, which can remove chloasma and delay senility. The raw materials used in the invention are common food materials and Chinese medicine homologous food materials, and the product provided by the invention is safe and efficient and is a real non-toxic product suitable for long-term drinking. People drinks the red jujube health-care beverage for a long time can efficiently improve face skin, remove chloasma, efficiently delay senility, and improve immunity of the organism. In the invention, the formula is scientific, the technology is advanced, the process is simple and convenient, and the standard, normalized and industrialized production is easy to realize.
Description
Technical field
The present invention relates to a kind of functions of removing chloasma beautifying face and moistering lotion red jujube health drink and production technology thereof.
Background technology
Red date has another name called date.Just be listed in one of " five fruits " (peach, Lee, plum, apricot, jujube) since ancient times, with a long history.The most outstanding characteristics of date are vitamin content height, and modern pharmacology is found, contains abundant nutrition such as protein, fat, carbohydrate, organic acid, vitamin A, vitamin C, micro-calcium several amino acids in the red date, has good beauty treatment health care efficacy.Along with the development of society, people's quality of the life improves constantly, and numerous women also improve day by day to the demand of beauty and health care health aspect, beautifying face and moistering lotion how, and the enhancing body immunity that delays senility becomes the problem of their special concern.Chloasma is the excessive heavy property disease of a kind of skin pigment, shows as the brown spot shape pigmentation at two cheeks and forehead position, is the common multiple skin disease of influence beauty treatment, also is the problem that makes women's headache most.The present invention utilizes multiple Chinese herbal medicines with beauty and health care functions such as red date to be base stock, prepares a kind of red jujube health drink, and this beverage has functions of removing chloasma, beautifying face and moistering lotion, and multi-efficiency such as delay senility.
Summary of the invention
The object of the invention provides a kind of red jujube health drink and production technology thereof with functions of removing chloasma effect.
It is to contain in every 1000ml beverage that red date of the present invention is supported formula for health beverage:
Red date 10～40g, black fungus 3～15g, Chinese yam 5～30g, American Ginseng 1～4g, the fruit of Chinese wolfberry 5～20g, the Radix Astragali 5～30g, rhodiola root 3～18g, grape seed extract 400～900mg, Pine Bark 20～100mg, glutathione 100～400mg, isoflavones 50～200mg, Tea Polyphenols 100～300mg, vitamin E 10～40mg, sucrose 5～30g, citric acid 5～20g, surplus is a pure water;
Described prescription is preferably in every 1000ml beverage and contains:
Red date 20～30g, black fungus 3～10g, Chinese yam 10～25g, American Ginseng 1～3g, the fruit of Chinese wolfberry 5～15g, the Radix Astragali 10～25g, rhodiola root 5～15g, grape seed extract 500～800mg, Pine Bark 30～60mg, glutathione 150～350mg, isoflavones 150～200mg, Tea Polyphenols 100～200mg, vitamin E 15～35mg, sucrose 10～25g, citric acid 5～15g, surplus is a pure water;
Contain in the more preferably every 1000ml beverage of described prescription:
Red date 20～25g, black fungus 5～10g, Chinese yam 15～20g, American Ginseng 1～2g, the fruit of Chinese wolfberry 10～15g, the Radix Astragali 15～20g, rhodiola root 5～10g, grape seed extract 600～700mg, Pine Bark 40～50mg, glutathione 200～300mg, isoflavones 150～200mg, Tea Polyphenols 150～200mg, vitamin E 20～30mg, sucrose 15～20g, citric acid 10～15g, surplus is a pure water;
Red jujube health drink production technology of the present invention is as follows:
Take by weighing red date by prescription, black fungus, Chinese yam, American Ginseng, the fruit of Chinese wolfberry, the Radix Astragali, rhodiola root, the deionized water that adds 1～2 times of medicinal material weight, 100～110 ℃ of steam treatment 30min replenish amount of purified water to 3～5 times of medicinal material weight, under current strength 0.6A/25w～1.5A/275w, carry out ultrasonic processing 10～30min with the probe type ultrasonic extraction apparatus, 85 ℃ then～100 ℃, decoct 60～120min, I filters to get filtrate; After the filtration dregs of a decoction are carried out secondary and decoct, the time is 60～90min, and II filters to get filtrate; Filtrate I and filtrate II are merged, add the pectase of filtrate weight 5～8%, stir, the control temperature is 40～60 ℃ of enzymolysis 1～3h; Filter behind the enzymolysis, add 0.3～0.6% shitosan in the filtrate and carry out clarifying treatment, the processing time is 2～6h, and then filters to get filtrate;
Take by weighing grape seed extract by prescription, Pine Bark, glutathione, isoflavones, Tea Polyphenols, vitamin E adds in the above-mentioned filtrate, and stirring fully dissolves it, take by weighing a certain amount of sucrose and citric acid by prescription then, the filtrate mouthfeel is adjusted, filtered once more after the adjustment, use the pure water constant volume; Decide quantities of beverage if surpass prescription institute before the constant volume, then carry out suitably concentrated, be concentrated into fill a prescription decide quantities of beverage;
Above-mentioned filtrate is carried out high-pressure homogeneous processing, and controlled pressure is 40～60Mpa, and temperature is 50～80 ℃, homogeneous 2～3 times; Carry out vacuum outgas behind the homogeneous, control vacuum is 30～40KPa, and temperature is 30～40 ℃; High temperature sterilization, sterilization temperature are 115～130 ℃, and sterilizing time is 6～15s; Can, check, packing gets product.
Red date distinguish the flavor of sweet warm in nature, return the taste warp, the function of tonifying middle-Jiao and Qi, blood-enriching face-nourishing, the mitigation property of medicine is arranged.Modern study finds that red date contains abundant nutrition such as protein, fat, carbohydrate, organic acid, vitamin A, vitamin C, micro-calcium several amino acids.Red date can improve body immunity, reduces serum cholesterol, improves seralbumin, the protection liver; Be rich in calcium and iron in the jujube, they play an important role to preventing and treating osteoporosis product anaemia; Red date also has good tonic effect to the people of body void after being ill; The rutin that jujube is contained is a kind of angiomalasia that makes, thereby the material that blood pressure is reduced has prophylactic-therapeutic effect to high blood pressure; Jujube can also antiallergy, remove stench strange taste, antitoxic heart-soothing and sedative, brain healthy, whet the appetite.
The black fungus flavor is sweet, property flat, returns stomach, large intestine channel; Have beneficial gas, moistening lung, benefit brain, make light of one's life by commiting suicide, cool blood, hemostasis, puckery intestines, invigorate blood circulation, strong will, support effect such as appearance; The content of iron is very abundant in the auricularia auriculajudae, can nourish blood and preserves youthful looks so often eat auricularia auriculajudae, and it is ruddy, radiant to make us skin, and can prevent and treat hypoferric anemia; Auricularia auriculajudae contains vitamin K, can reduce blood clotting, and the generation of prevention DVT has the effect of atherosclerotic of preventing and treating and coronary heart disease; Colloid in the auricularia auriculajudae can put together and excretes remaining in dust, impurity absorption in the digestion, thereby plays the effect that intestines are washed in clearing stomach; It also has endogenous foreign matters such as gall stone, kidney stones dissolves function more significantly; Its fiber substance function that helps digest in addition has dissolving and molten effect to foreign matters such as the hair that is difficult to digest eaten unintentionally, husk, wooden slag, sand, metal fillings, and therefore, it is the indispensable health food of mine, chemical industry and textile worker; Auricularia auriculajudae contains anti-tumor active substance, can strengthen immunity of organisms, but often edible cancer-resisting.
Chinese yam is sweet, warm, flat, nontoxic.The main nutritive value of Chinese yam: 1. invigorating spleen and reinforcing stomach, aid digestion: Chinese yam contains materials such as amylase, polyphenol oxidase, helps the taste digestion and absorption function, is the product of the medicine-food two-purpose of flat tonifying spleen and stomach simply.No matter the spleen sun loses or stomach-Yin deficiency, all edible.Use always clinically and control illnesss such as weakness of the spleen and the stomach, that the few body of food is tired, have loose bowels; 2. nourishing kidney and replenishing pneuma: Chinese yam contains various nutrients, and strong body is arranged, the effect of nourishing kidney and replenishing pneuma.Generally deficiency of the kidney seminal emission, diseases such as the women leukorrhea is many, frequent urination all can be obeyed it; 3. beneficial lung cough-relieving: Chinese yam contains saponin, lymphatic temperament, have lubricated, the effect of moistening, thus can beneficial lung qi, support lung yin, treat the deficiency syndrome of the lung phlegm disease of chronic cough of coughing; 4. reduction blood sugar: Chinese yam contains mucus protein, and the effect that reduces blood sugar is arranged, and can be used for treating diabetes, is diabetes patient's dietotherapy good merchantable brand; 5. promote longevity: Chinese yam contains a large amount of mucus albumen, vitamin and trace element, can effectively stop the precipitation of blood fat at vascular wall, and prevention painstaking effort disease obtains that beneficial will is calmed the nerves, effect of prolonging life; 6. anti-hepatic coma: discover that in recent years Chinese yam has sedation, can come anti-hepatic coma.
Sweet, the little hardship of American Ginseng, cold, the thoughts of returning home, lung, kidney channel.Saponin in the American Ginseng can effectively strengthen nervous centralis, reach with all worries set aside with fixed attention, eliminate tired, strengthen effects such as memory, applicable to insomnia, irritated, be losing one's memory and symptom such as senile dementia; The informal dress American Ginseng can anti-arrhythmia, resist myocardial ischemia, anti-myocardium oxidation, strengthen cardiac contractility ability, and the patients with coronary heart disease symptom shows as deficiency of both qi and yin, nervously breathes hard and can take American Ginseng for a long time, and is evident in efficacy.Efficacy of American ginseng also is to regulate blood pressure, can effectively reduce temporary and the persistence blood pressure, helps the recovery of diseases such as hypertension, arrhythmia cordis, coronary heart disease, acute myocardial infarction, cerebral thrombus; American Ginseng is as the first-selected medicinal material of qi-tonifying health-care, can promote that haemocyanin is synthetic, bone marrow protein is synthetic, organ albumen is synthetic etc., improves immunity of organisms, suppresses growth of cancer cells, effectively resists cancer.
Fruit of Chinese wolfberry flavor is sweet, property is put down has the effect of liver-kidney tonifying, and " obey hard muscles and bones for a long time, it is not old to make light of one's life by commiting suicide, cold-resistant heat in the Compendium of Material Medica record." traditional Chinese medical science commonly used it treat liver-kidney Yin deficiency, soreness and weakness of waist and knees, dizziness, forgetful, dizzy, many tears of blurred vision, quench one's thirst, illness such as seminal emission.Modern pharmacology studies confirm that the fruit of Chinese wolfberry can regulate body's immunity, have and strengthen the nospecific immunity effect; Can effectively suppress tumor growth and cell mutation; Can improve blood two-story valley peptide peroxidase (GSH-Px) vigor and erythrocyte superoxide dismutase (SOD) vigor, have delaying senility function; Have the effect to Green Tea Extract, nephridial tissue MDA level is descended, the prevention mitochondria is aging, and its function is made moderate progress; Hepatic injury is had repair, and its mechanism may be by stoping the damage of endoplasmic reticulum, promote the synthetic and detoxication of protein, recovering hepatocellular function, and promote hepatocellular regeneration; Regulate the effect of blood fat and aspects such as blood sugar, promotion hematopoiesis function.
Grape seed extract is that the effective active nutrition of extracting from natural grape seed is equipped with the refining nutraceutical that form of primary raw material such as vitamin E.Grape seed extract is the new and effective natural material that can not synthesize in a kind of human body that extracts from grape pip.It is anti-oxidant, the strongest material of removing free radical ability that present occurring in nature is found, its antioxidation activity is 50 times, ascorbic 20 times of the plain E of dimension, it can effectively remove unnecessary free radical in the human body, has the superpower effect that delays senility and strengthen immunity.Anti-oxidant, antiallergy, antifatigue are built up health, are improved sub-health state and delay senility, improve symptoms such as irritated irritability, dizzy weak, failure of memory.
Pine Bark is a class material that extracts from pine bark.Wherein contain the compound that is called OPCs (OPC oligomer) in a large number.OPCs is as the effectively stranglehold base effect of famous antioxidant, and free radical is at DD, angiocardiopathy, and eye-blurred, aspects such as sunburn and early ageing play an important role.
Tea Polyphenols (Tea Polyphenols) is the general name of polyphenols in the tealeaves, comprises flavanol compound, anthocyanin class, flavonoids, flavonols and phenolic acid class etc.Wherein important with flavanol compound material (catechin).Tea Polyphenols claims tea to tan or tea tannin again, is one of Main Ingredients and Appearance that forms the tealeaves color, smell and taste, also is one of Main Ingredients and Appearance that has in the tealeaves health care.Effect with the harmful free radical of very strong elimination; Anti-aging effects; Radiation resistance; Inhibitory action to cancer cell; Antibiotic, bactericidal action; Inhibitory action to AIDS virus; Beneficial to the smoker, can clean lung's nicotine.
The major physiological function of glutathione is a Green Tea Extract, and is anti-ageing, anti-oxidant.The polyradical excessively that organism metabolism produces can damage biomembrane, and the invasion and attack life macromolecule promotes body aging, and induced tumor or arteriosclerotic generation, and glutathione can be eliminated free radical, can play strong protective effect, can also improve body immunity; Glutathione has strong protective effect for symptoms such as radioactive ray, the caused leucocyte minimizings of radiopharmaceutical; Glutathione can stop oxygenated haemoglobin, in the protection sulfydryl enzyme molecule-the SH base, helps the performance of enzymatic activity, and can recover in the disrupted enzyme molecule-active function of SH base, makes enzyme recover activity again; Glutathione can also suppress the ethanol infringement fatty liver that liver produced; The chemical, biological defense system of glutathione in human body plays an important role, and has many-sided physiological function; Glutathione can be used as the main component of treatment cataract medicament.
Isoflavones is a kind of in the flavone compound, mainly is present in the legume, and isoflavones is a class secondary metabolite that forms in the soybeans they grow.Isoflavones has antioxidation; Isoflavones is typical phytoestrogen, isoflavones can replace estrogen to combine the performance estrogen-like action with ER, can disturb estrogen to combine again with ER, show as the effect of antiestrogenic sample, the estrogen-like action of isoflavones is withdrawn relevant disease such as blood fat rising, atherosclerotic and osteoporosis etc. to elderly woman is many with hormone, and certain prevention and therapeutic action are arranged; The isoflavones compound can improve the myocardial ischemia symptom by different approach, and hemangiectasis, inhibition platelet aggregation reduce blood cholesterol and content of triglyceride, and anti-arrhythmia cordis effect is arranged; Isoflavones also has anti-cancer and anticancer effect.
The rhodiola root flavor is sweet, and hardship is flat.Return lung, the heart channel of Hang-Shaoyin.Qi and activate blood circulation is promoted blood circulation and is relievingd asthma, and is used for qi deficiency to blood stasis, chest impediment and cardialgia, hemiplegia, burnout asthma.Rhodiola root has various health-care: 1. anti-anoxic, antifatigue: can improve the binding ability of hemoglobin and oxygen rapidly, improve blood oxygen saturation, reduce the oxygen demand of body, increase exercise tolerance, the back of recovering to move is tired.2. antibacterial action: rhodiola root contains volume hyoscine, kaempferol etc. and has the anti-inflammation composition; Content of tannin is also maximum, and Bearberry Extract shields at mucomembranous surface, prevent too much secretion, stop excessive hemorrhage, effective in cure to cough, expectoration and women's leucorrhea increasing that lung inflammation causes.3. analgesic activity: [experiment] adopts mouse to tremble the cage method, gets mouse adjustable shelf and lever, starts the note line and rouses soon, to trace the mouse activity.Lumbar injection rhodioside (400mg/kg) and physiological saline (control group).The result shows that the medication group has the effect (p＜0.001) of obvious inhibition mouse mobility.4. radiation resistance: obviously suppress the generation of the radiation-induced heart and liver L PO (lipid peroxide), lipid and cell membrane are played a protective role.5. delaying senility function: significantly improve the activity of body SOD (superoxide dismutase), remove free radical, suppress lipid peroxide and generate.6. to the dual regulation of internal system: the secretion of bidirectional modulation adrenal hormone, sex hormone etc.
The present invention is in conjunction with traditional Chinese medicine theory and modern scientific theory, with natural Chinese medicinal herb such as red dates is primary raw material, prepare and have eliminating chloasma, the red jujube health drink of function of delaying senility, the present invention is raw materials used to be bread and cheese raw material and integration of drinking and medicinal herbs raw material, product safety of the present invention is effective, and the nontoxic product in true border is fit to long-term drinking.Long-term drinking can effectively be improved facial skin, eliminating chloasma, and effectively delay senility, improve immunity of organisms.Scientific formulation of the present invention, advanced technology, technology is easy, is easy to realize standardization, standardization, batch production production.
The specific embodiment
The present invention is further illustrated for following examples.
Embodiment 1
Present embodiment red jujube health drink prescription is to contain in every 1000ml beverage:
Red date 40g, black fungus 15g, Chinese yam 20g, American Ginseng 3g, fruit of Chinese wolfberry 15g, Radix Astragali 20g, rhodiola root 15g, grape seed extract 500mg, Pine Bark 30mg, glutathione 200mg, isoflavones 100mg, Tea Polyphenols 120mg, vitamin E 15mg, sucrose 15g, citric acid 5g, surplus is a pure water;
Present embodiment red jujube health drink production technology is as follows:
Take by weighing red date by prescription, black fungus, Chinese yam, American Ginseng, the fruit of Chinese wolfberry, the Radix Astragali, rhodiola root, the deionized water that adds 1 times of medicinal material weight, 100 ℃ of steam treatment 30min replenish amount of purified water to 3 times of medicinal material weight, under current strength 1.5A/275w, carry out ultrasonic processing 10min with the probe type ultrasonic extraction apparatus, 100 ℃ then, decoct 60min, I filters to get filtrate; After the filtration dregs of a decoction are carried out secondary and decoct, the time is 60, and II filters to get filtrate; Filtrate I and filtrate II are merged, add the pectase of filtrate weight 5%, stir, the control temperature is 60 ℃ of enzymolysis 3h; Filter behind the enzymolysis, the shitosan of adding 0.3% carries out clarifying treatment in the filtrate, and the processing time is 6h, and then filters to get filtrate;
Take by weighing grape seed extract by prescription, Pine Bark, glutathione, isoflavones, Tea Polyphenols, vitamin E adds in the above-mentioned filtrate, and stirring fully dissolves it, take by weighing a certain amount of sucrose and citric acid by prescription then, the filtrate mouthfeel is adjusted, filtered once more after the adjustment, use the pure water constant volume; Decide quantities of beverage if surpass prescription institute before the constant volume, then carry out suitably concentrated, be concentrated into fill a prescription decide quantities of beverage;
Above-mentioned filtrate is carried out high-pressure homogeneous processing, and controlled pressure is 40Mpa, and temperature is 80 ℃, homogeneous 3 times; Carry out vacuum outgas behind the homogeneous, control vacuum is 30KPa, and temperature is 40 ℃; High temperature sterilization, sterilization temperature are 115 ℃, and sterilizing time is 15s; Can, check, packing gets product.
Embodiment 2
Present embodiment red jujube health drink prescription is to contain in every 1000ml beverage:
Red date 25g, black fungus 10g, Chinese yam 18g, American Ginseng 2g, fruit of Chinese wolfberry 12g, Radix Astragali 18g, rhodiola root 8g, grape seed extract 650mg, Pine Bark 45mg, glutathione 280mg, isoflavones 160mg, Tea Polyphenols 150mg, vitamin E 25mg, sucrose 25g, citric acid 10g, surplus is a pure water;
Present embodiment red jujube health drink production technology is as follows:
Take by weighing red date by prescription, black fungus, Chinese yam, American Ginseng, the fruit of Chinese wolfberry, the Radix Astragali, rhodiola root, the deionized water that adds 2 times of medicinal material weight, 100 ℃ of steam treatment 30min replenish amount of purified water to 4 times of medicinal material weight, under current strength 0.6A/25w, carry out ultrasonic processing 20min with the probe type ultrasonic extraction apparatus, 100 ℃ then, decoct 120min, I filters to get filtrate; After the filtration dregs of a decoction are carried out secondary and decoct, the time is 80min, and II filters to get filtrate; Filtrate I and filtrate II are merged, add the pectase of filtrate weight 8%, stir, the control temperature is 40 ℃ of enzymolysis 3h; Filter behind the enzymolysis, the shitosan of adding 0.5% carries out clarifying treatment in the filtrate, and the processing time is 5h, and then filters to get filtrate;
Take by weighing grape seed extract by prescription, Pine Bark, glutathione, isoflavones, Tea Polyphenols, vitamin E adds in the above-mentioned filtrate, and stirring fully dissolves it, take by weighing a certain amount of sucrose and citric acid by prescription then, the filtrate mouthfeel is adjusted, filtered once more after the adjustment, use the pure water constant volume; Decide quantities of beverage if surpass prescription institute before the constant volume, then carry out suitably concentrated, be concentrated into fill a prescription decide quantities of beverage;
Above-mentioned filtrate is carried out high-pressure homogeneous processing, and controlled pressure is 60Mpa, and temperature is 50 ℃, homogeneous 3 times; Carry out vacuum outgas behind the homogeneous, control vacuum is 30KPa, and temperature is 40 ℃; High temperature sterilization, sterilization temperature are 120 ℃, and sterilizing time is 12s; Can, check, packing gets product.
Embodiment 3
Present embodiment red jujube health drink prescription is to contain in every 1000ml beverage:
Red date 30g, black fungus 10g, Chinese yam 20g, American Ginseng 2g, fruit of Chinese wolfberry 10g, Radix Astragali 20g, rhodiola root 10g, grape seed extract 600mg, Pine Bark 50mg, glutathione 300mg, isoflavones 150mg, Tea Polyphenols 120mg, vitamin E 25mg, sucrose 18g, citric acid 12g, surplus is a pure water;
Present embodiment red jujube health drink production technology is as follows:
Take by weighing red date by prescription, black fungus, Chinese yam, American Ginseng, the fruit of Chinese wolfberry, the Radix Astragali, rhodiola root, the deionized water that adds 2 times of medicinal material amounts, 110 ℃ of steam treatment 30min replenish amount of purified water to 5 times of medicinal material weight, under current strength 0.9A/75w, carry out ultrasonic processing 20min with the probe type ultrasonic extraction apparatus, 100 ℃ then, decoct 120min, I filters to get filtrate; After the filtration dregs of a decoction are carried out secondary and decoct, the time is 90min, and II filters to get filtrate; Filtrate I and filtrate II are merged, add the pectase of filtrate weight 6%, stir, the control temperature is 50 ℃ of enzymolysis 3h; Filter behind the enzymolysis, the shitosan of adding 0.5% carries out clarifying treatment in the filtrate, and the processing time is 4h, and then filters to get filtrate;
Take by weighing grape seed extract by prescription, Pine Bark, glutathione, isoflavones, Tea Polyphenols, vitamin E adds in the above-mentioned filtrate, and stirring fully dissolves it, take by weighing a certain amount of sucrose and citric acid by prescription then, the filtrate mouthfeel is adjusted, filtered once more after the adjustment, use the pure water constant volume; Decide quantities of beverage if surpass prescription institute before the constant volume, then carry out suitably concentrated, be concentrated into fill a prescription decide quantities of beverage;
Above-mentioned filtrate is carried out high-pressure homogeneous processing, and controlled pressure is 50Mpa, and temperature is 60 ℃, homogeneous 3 times; Carry out vacuum outgas behind the homogeneous, control vacuum is 35KPa, and temperature is 35 ℃; High temperature sterilization, sterilization temperature are 120 ℃, and sterilizing time is 12s; Can, check, packing gets product.
Embodiment 4
Present embodiment red jujube health drink prescription is to contain in every 1000L beverage:
Red date 30kg, black fungus 8kg, Chinese yam 20kg, American Ginseng 3kg, fruit of Chinese wolfberry 15kg, Radix Astragali 15kg, rhodiola root 10kg, grape seed extract 600g, Pine Bark 50g, glutathione 300g, isoflavones 200g, Tea Polyphenols 180g, vitamin E 30g, sucrose 15kg, citric acid 10kg, surplus is a pure water;
Present embodiment red jujube health drink production technology is as follows:
Take by weighing red date by prescription, black fungus, Chinese yam, American Ginseng, the fruit of Chinese wolfberry, the Radix Astragali, rhodiola root, the deionized water that adds 2 times of medicinal material weight, 110 ℃ of steam treatment 30min replenish amount of purified water to 5 times of medicinal material weight, under current strength 0.9A/75w, carry out ultrasonic processing 20min with the probe type ultrasonic extraction apparatus, 100 ℃ then, decoct 100min, I filters to get filtrate; After the filtration dregs of a decoction are carried out secondary and decoct, the time is 80min, and II filters to get filtrate; Filtrate I and filtrate II are merged, add the pectase of filtrate weight 8%, stir, the control temperature is 50 ℃ of enzymolysis 2.5h; Filter behind the enzymolysis, the shitosan of adding 0.6% carries out clarifying treatment in the filtrate, and the processing time is 5h, and then filters to get filtrate;
Take by weighing grape seed extract by prescription, Pine Bark, glutathione, isoflavones, Tea Polyphenols, vitamin E adds in the above-mentioned filtrate, and stirring fully dissolves it, take by weighing a certain amount of sucrose and citric acid by prescription then, the filtrate mouthfeel is adjusted, filtered once more after the adjustment, use the pure water constant volume; Decide quantities of beverage if surpass prescription institute before the constant volume, then carry out suitably concentrated, be concentrated into fill a prescription decide quantities of beverage;
Above-mentioned filtrate is carried out high-pressure homogeneous processing, and controlled pressure is 50Mpa, and temperature is 65 ℃, homogeneous 2 times; Carry out vacuum outgas behind the homogeneous, control vacuum is 35KPa, and temperature is 40 ℃; High temperature sterilization, sterilization temperature are 120 ℃, and sterilizing time is 12s; Can, check, packing gets product.
Health drink chloasma-dispelling function human feeding trial of the present invention
1 material and method
1.1 sample: given the test agent " red jujube health drink " is a brown liquid.
1.2 the experimenter includes standard in
1.2.1 study subject: press the principle of voluntariness and select the age at the chloasma adult patient between 18-65 year.
1.2.2 the person's of including in standard:
Facial filbert to dark brown, well-defined patch, symmetry distributes usually, the no inflammatory performance and the scales of skin that peel off.
There is not obvious subjective symptoms;
After mainly occurring in puberty, women's pilosity;
The state of an illness has certain seasonality, and Xia Chongdong is light;
Do not have obvious endocrine system disease, and get rid of the pigmentation that other disease causes.
1.3 experimenter's exclusion standard:
1.3.1 the age is under-18s or over-65s person, gestation or women breast-feeding their children, allergic constitution and to this health food allergy sufferers;
1.3.2 merge to have the inclination, serious disease and endocrine system diseases such as the cerebrovascular, liver, kidney and hemopoietic system the mental patient;
1.3.3 wine-head or smoker;
1.3.4 take the article relevant in a short time, have influence on judgement person to the result with being tried function;
1.3.5 do not take given the test agent in accordance with regulations, can't judge effect or data not umbra sound curative effect or security judgement person.
1.4 experimental design and grouping require: adopt two kinds of control design between self and group.110 experimenters are divided into test-meal group and control group at random, consider influence result's principal element such as sex, age, economic situation etc. as far as possible, carry out harmony to check, with the comparativity between the assurance group.Positive controls 55 examples, test-meal group 55 examples.
1.5 the dosage of given the test agent and using method: the test-meal group is taken red jujube health drink, every day 1 time, each 500ml, continuous 45 days.Control group is taken glutathione 100mg, vitamin C 200mg, equal every day 2 times, continuous 45 days.The experimenter stops using other articles for use oral and the relevant face-beautifying and spot-removing of external application at duration of test.Duration of test does not change original eating habit, normal diet.
2 observation index:
2.1 safety indexes:
2.1.1 general situation comprises spirit, sleep, diet, stool and urine, blood pressure etc.;
2.1.2 blood, urine, just routine inspection:
2.1.3 liver, kidney function test
2.1.4 Chest X-rays, electrocardiogram, Abdominal B type ultrasonography inspection (once) in pretest inspection;
2.1.5 bad reaction is observed;
2.2 symptom is observed: poor appetite, weak, irritated, dizzy, dim eyesight, distraction, have palpitation, breathe hard etc.
2.3 effect index:
2.3.1 facial area chloasma area size detection: the area (mm that is tried the whole facial area chloasma in front and back with tape measure
2)
2.3.2 facial area chloasma shade detects: according to Institute of Geography, Academia Sinica's development and design, brown (Y+M+BK i.e. Huang+magenta+black folded look) colour atla in " practical standard colour atla " (front page) that Mapping Press published in 1992 is the criterion of the chloasma depth: I degree (15,20,5), II degree (30,40,10), III (40,60,15)
3 data are handled and the result judges
Chloasma color integration before and after the test-meal and area change are added up, calculated efficient simultaneously.Colour atla I degree, II degree and III degree were counted respectively 1 minute, 2 minutes and 3 minutes.
Effect criterion
Effectively: chloasma color decline I degree, area reduces greater than 10%, and does not produce new chloasma.
Invalid: chloasma color and area do not have significant change
Test data is a measurement data, and available t check is analyzed.All own control data can have been adopted paired t-test, two groups of means relatively adopt t check in groups, and the latter need carry out homogeneity test of variance, and the data of Non-Gaussian Distribution or heterogeneity of variance are carried out suitable variable conversion, wait to satisfy the normal state variance neat after, carry out the t check with data converted; If translation data still can not satisfy the neat requirement of normal state variance, use t ' check or rank test instead; But the coefficient of variation too data of big (as CV＞50%) is used rank test.
Efficient employing X
2Check is tested.The total routine number of four fold table is less than 40, or total routine number is equal to or greater than 40 but theoretical value occurs and be equal to or less than at 1 o'clock, should use definite probabilistic method instead.Efficient employing X
2Check.
The result judges
Test-meal group chloasma area decreased average, and more than or equal to 10%, the color integration obviously descends, and relatively reaches before and after self with control group to compare, and difference all has conspicuousness, and does not produce new chloasma, and this given the test agent of decidable has the effect of chloasma-dispelling function.
4 result of the tests:
4.1 general situation:
Observing experimenter's 110 examples altogether, is the women entirely, effective case 100 examples, test-meal group 50 examples, the oldest 50 years old, minimum 22 years old, the course of disease 5～152 months; Control group 50 examples, the oldest 52 years old, minimum 23 years old, the course of disease 6～144 months.Two groups of patients all suffer from symptoms such as in various degree insomnia, palpitaition, constipation, dysphoria, irregular menstruation.The many symmetries of symptom betide face, especially are mainly in cheek, bridge of the nose, mouthful week, forehead, plate multidigit butterfly wing, yellowish-brown or crineous.All took the beauty treatment and eliminating spot medicine before both patients test, effect is undesirable.Two groups of patient's physical data differences do not have conspicuousness, have comparativity, the results are shown in Table 1.
Situation relatively as the test-meal of table 1. red jujube health drink was last
| Group | The example number | Age (year) | Chloasma color (integration) | Chloasma area (mm 2) |
| The test-meal group | 50 | 42.62±13.09 | 2.38±0.56 | ?3327±1851 |
| Control group | 50 | 44.12±16.89 | 2.29±0.73 | ?3351±1983 |
4.2 safety indexes detects before and after the red jujube health drink test-meal
Safety indexes detects before and after the test-meal of table 2. red jujube health drink
Every index is substantially in normal range (NR) before and after the experiment
By table 2 as seen, took red jujube health drink continuously 45 days, the every detection index of all experimenters is all in normal range (NR).Object Selection met the requirements before test was described, red jujube health drink does not have any damage to experimenter's body health.
4.3 chloasma change color before and after the red jujube health drink test-meal:
Chloasma change color (integration) before and after the test-meal of table 3. red jujube health drink
By table 3 as seen, test-meal group chloasma color integral mean decline 0.54 degree on average decreases by 22.7%, with poor heteropole before the test-meal remarkable (P＜0.01), does not have conspicuousness with the control group comparing difference.The result shows that red jujube health drink is very obvious to the chloasma color effect that goes down.
4.4 chloasma area change before and after the red jujube health drink test-meal
Chloasma area change (mm before and after the test-meal of table 4 red jujube health drink
2)
By table 4 as seen, test-meal group chloasma area decreased average 325mm
2, reach utmost point significance (P＜0.01) with comparing difference before the test-meal, there is not conspicuousness with the control group comparing difference.It is remarkable that the result shows that red date health care reduces effect to the chloasma area.
4.6 effect is relatively:
By table 5 as seen, after the test-meal of test-meal group in functions of removing chloasma 50 examples 35 examples effectively, efficient is 70%.The result shows that red jujube health drink functions of removing chloasma effect is remarkable.
Table 5. effect relatively
Compare P=0.33 (difference not statistically significant) between the # group
4.7 doing well,improving situation after the red jujube health drink test-meal:
Doing well,improving situation after the test-meal of table 6. red jujube health drink
() is control group
By table 6 as seen, poor appetite, weak, irritated, dizzy, dim eyesight, distraction after the test-meal group test-meal, symptom such as have palpitation, breathe hard all have improvement.
4.8 test-meal preabdomen B ultrasonic (liver, courage, pancreas, spleen, two kidney), electrocardiogram, Chest X-rays show no obvious abnormalities.Test-meal group and control group are not all observed tangible bad reaction and allergic reaction.
5 conclusions:
110 experimenters are divided into test-meal group and control group at random, and the test-meal group is taken red jujube health drink, every day 1 time, each 500ml, continuous 45 days.Control group is taken glutathione 100mg, vitamin C 200mg, equal every day 2 times, continuous 45 days.Test-meal group chloasma color integral mean decline 0.54 degree on average decreases by 22.7%, with poor heteropole before the test-meal remarkable (P＜0.01), does not have conspicuousness with the control group comparing difference.Test-meal group chloasma area decreased average 325mm
2, reach utmost point significance (P＜0.01) with comparing difference before the test-meal, there is not conspicuousness with the control group comparing difference.The test-meal group is efficient to be 70%, does not have conspicuousness with the positive controls comparing difference.Red jujube health drink to alimentary anemia experimenter's poor appetite, weak, irritated, dizzy, dim eyesight, distraction, having palpitation, breathe hard etc. has the improvement effect.Blood, urine, just routine inspection before and after test-meal group and the control group test-meal, liver, kidney function test show no obvious abnormalities, and all do not observe tangible bad reaction and allergic reaction during the test-meal.Test-meal group and control group test preabdomen B ultrasonic, electrocardiogram, Chest X-rays show no obvious abnormalities.The result shows that red jujube health drink has the function of functions of removing chloasma.
Claims (9)
1. red jujube health drink with functions of removing chloasma effect, it is characterized in that, prescription is for containing in every 1000ml beverage: red date 10～40g, black fungus 3～15g, Chinese yam 5～30g, American Ginseng 1～～4g, the fruit of Chinese wolfberry 5～20g, the Radix Astragali 5～30g, rhodiola root 3～18g, grape seed extract 400～900mg, Pine Bark 20～100mg, glutathione 100～400mg, isoflavones 50～200mg, Tea Polyphenols 100～300mg, vitamin E 10～40mg, sucrose 5～30g, citric acid 5～20g, surplus is a pure water.
2. red jujube health drink according to claim 1, it is characterized in that, described prescription is preferably in every 1000ml beverage and contains: red date 20～30g, black fungus 3～10g, Chinese yam 10～25g, American Ginseng 1～3g, the fruit of Chinese wolfberry 5～15g, the Radix Astragali 10～25g, rhodiola root 5～15g, grape seed extract 500～800mg, Pine Bark 30～60mg, glutathione 150～350mg, isoflavones 150～200mg, Tea Polyphenols 100～200mg, vitamin E 15～35mg, sucrose 10～25g, citric acid 5～15g, surplus is a pure water.
3. red jujube health drink according to claim 1, it is characterized in that, contain in the more preferably every 1000ml beverage of described prescription: red date 20～25g, black fungus 5～10g, Chinese yam 15～20g, American Ginseng 1～2g, the fruit of Chinese wolfberry 10～15g, the Radix Astragali 15～20g, rhodiola root 5～10g, grape seed extract 600～700mg, Pine Bark 40～50mg, glutathione 200～300mg, isoflavones 150～200mg, Tea Polyphenols 150～200mg, vitamin E 20～30mg, sucrose 15～20g, citric acid 10～15g, surplus is a pure water.
4. red jujube health drink production technology with functions of removing chloasma effect is characterized in that production technology is:
Take by weighing red date by prescription, black fungus, Chinese yam, American Ginseng, the fruit of Chinese wolfberry, the Radix Astragali, rhodiola root, the deionized water that adds 1～2 times of medicinal material weight, 100～110 ℃ of steam treatment 30min replenish amount of purified water to 3～5 times of medicinal material weight, under current strength 0.6A/25w～1.5A/275w, carry out ultrasonic processing 10～30min with the probe type ultrasonic extraction apparatus, 85 ℃ then～100 ℃, decoct 60～120min, I filters to get filtrate; After the filtration dregs of a decoction are carried out secondary and decoct, the time is 60～90min, and II filters to get filtrate; Filtrate I and filtrate II are merged, add the pectase of filtrate weight 5～8%, stir, the control temperature is 40～60 ℃ of enzymolysis 1～3h; Filter behind the enzymolysis, add 0.3～0.6% shitosan in the filtrate and carry out clarifying treatment, the processing time is 2～6h, and then filters to get filtrate;
Take by weighing grape seed extract by prescription, Pine Bark, glutathione, isoflavones, Tea Polyphenols, vitamin E adds in the above-mentioned filtrate, and stirring fully dissolves it, take by weighing a certain amount of sucrose and citric acid by prescription then, the filtrate mouthfeel is adjusted, filtered once more after the adjustment, use the pure water constant volume; Decide quantities of beverage if surpass prescription institute before the constant volume, then carry out suitably concentrated, be concentrated into fill a prescription decide quantities of beverage;
Above-mentioned filtrate is carried out high-pressure homogeneous processing, and controlled pressure is 40～60Mpa, and temperature is 50～80 ℃, homogeneous 2～3 times; Carry out vacuum outgas behind the homogeneous, control vacuum is 30～40KPa, and temperature is 30～40 ℃; High temperature sterilization, sterilization temperature are 115～130 ℃, and sterilizing time is 6～15s; Can, check, packing gets product;
Described prescription is to contain in every 1000ml beverage: red date 10～40g, black fungus 3～15g, Chinese yam 5～30g, American Ginseng 1～4g, the fruit of Chinese wolfberry 5～20g, the Radix Astragali 5～30g, rhodiola root 3～18g, grape seed extract 400～900mg, Pine Bark 20～100mg, glutathione 100～400mg, isoflavones 50～200mg, Tea Polyphenols 100～300mg, vitamin E 10～40mg, sucrose 5～30g, citric acid 5～20g, surplus is a pure water.
5. red jujube health drink production technology according to claim 4 is characterized in that, production technology is:
Take by weighing red date by prescription, black fungus, Chinese yam, American Ginseng, the fruit of Chinese wolfberry, the Radix Astragali, rhodiola root, the deionized water that adds 1 times of medicinal material weight, 100 ℃ of steam treatment 30min replenish amount of purified water to 3 times of medicinal material weight, under current strength 1.5A/275w, carry out ultrasonic processing 10min with the probe type ultrasonic extraction apparatus, 100 ℃ then, decoct 60min, I filters to get filtrate; After the filtration dregs of a decoction are carried out secondary and decoct, the time is 60, and II filters to get filtrate; Filtrate I and filtrate II are merged, add the pectase of filtrate weight 5%, stir, the control temperature is 60 ℃ of enzymolysis 3h; Filter behind the enzymolysis, the shitosan of adding 0.3% carries out clarifying treatment in the filtrate, and the processing time is 6h, and then filters to get filtrate;
Take by weighing grape seed extract by prescription, Pine Bark, glutathione, isoflavones, Tea Polyphenols, vitamin E adds in the above-mentioned filtrate, and stirring fully dissolves it, take by weighing a certain amount of sucrose and citric acid by prescription then, the filtrate mouthfeel is adjusted, filtered once more after the adjustment, use the pure water constant volume; Decide quantities of beverage if surpass prescription institute before the constant volume, then carry out suitably concentrated, be concentrated into fill a prescription decide quantities of beverage;
Above-mentioned filtrate is carried out high-pressure homogeneous processing, and controlled pressure is 40Mpa, and temperature is 80 ℃, homogeneous 3 times; Carry out vacuum outgas behind the homogeneous, control vacuum is 30KPa, and temperature is 40 ℃; High temperature sterilization, sterilization temperature are 115 ℃, and sterilizing time is 15s; Can, check, packing gets product;
Described prescription is to contain in every 1000ml beverage:
Red date 40g, black fungus 15g, Chinese yam 20g, American Ginseng 3g, fruit of Chinese wolfberry 15g, Radix Astragali 20g, rhodiola root 15g, grape seed extract 500mg, Pine Bark 30mg, glutathione 200mg, isoflavones 100mg, Tea Polyphenols 120mg, vitamin E 15mg, sucrose 15g, citric acid 5g, surplus is a pure water.
6. red jujube health drink production technology according to claim 4 is characterized in that, production technology is:
Take by weighing red date by prescription, black fungus, Chinese yam, American Ginseng, the fruit of Chinese wolfberry, the Radix Astragali, rhodiola root, the deionized water that adds 2 times of medicinal material weight, 100 ℃ of steam treatment 30min replenish amount of purified water to 4 times of medicinal material weight, under current strength 0.6A/25w, carry out ultrasonic processing 20min with the probe type ultrasonic extraction apparatus, 100 ℃ then, decoct 120min, I filters to get filtrate; After the filtration dregs of a decoction are carried out secondary and decoct, the time is 80min, and II filters to get filtrate; Filtrate I and filtrate II are merged, add the pectase of filtrate weight 8%, stir, the control temperature is 40 ℃ of enzymolysis 3h; Filter behind the enzymolysis, the shitosan of adding 0.5% carries out clarifying treatment in the filtrate, and the processing time is 5h, and then filters to get filtrate;
Take by weighing grape seed extract by prescription, Pine Bark, glutathione, isoflavones, Tea Polyphenols, vitamin E adds in the above-mentioned filtrate, and stirring fully dissolves it, take by weighing a certain amount of sucrose and citric acid by prescription then, the filtrate mouthfeel is adjusted, filtered once more after the adjustment, use the pure water constant volume; Decide quantities of beverage if surpass prescription institute before the constant volume, then carry out suitably concentrated, be concentrated into fill a prescription decide quantities of beverage;
Above-mentioned filtrate is carried out high-pressure homogeneous processing, and controlled pressure is 60Mpa, and temperature is 50 ℃, homogeneous 3 times; Carry out vacuum outgas behind the homogeneous, control vacuum is 30KPa, and temperature is 40 ℃; High temperature sterilization, sterilization temperature are 120 ℃, and sterilizing time is 12s; Can, check, packing gets product;
Described prescription is to contain in every 1000ml beverage:
Red date 25g, black fungus 10g, Chinese yam 18g, American Ginseng 2g, fruit of Chinese wolfberry 12g, Radix Astragali 18g, rhodiola root 8g, grape seed extract 650mg, Pine Bark 45mg, glutathione 280mg, isoflavones 160mg, Tea Polyphenols 150mg, vitamin E 25mg, sucrose 25g, citric acid 10g, surplus is a pure water.
7. red jujube health drink production technology according to claim 4 is characterized in that, production technology is:
Take by weighing red date by prescription, black fungus, Chinese yam, American Ginseng, the fruit of Chinese wolfberry, the Radix Astragali, rhodiola root, the deionized water that adds 2 times of medicinal material amounts, 110 ℃ of steam treatment 30min replenish amount of purified water to 5 times of medicinal material weight, under current strength 0.9A/75w, carry out ultrasonic processing 20min with the probe type ultrasonic extraction apparatus, 100 ℃ then, decoct 120min, I filters to get filtrate; After the filtration dregs of a decoction are carried out secondary and decoct, the time is 90min, and II filters to get filtrate; Filtrate I and filtrate II are merged, add the pectase of filtrate weight 6%, stir, the control temperature is 50 ℃ of enzymolysis 3h; Filter behind the enzymolysis, the shitosan of adding 0.5% carries out clarifying treatment in the filtrate, and the processing time is 4h, and then filters to get filtrate;
Take by weighing grape seed extract by prescription, Pine Bark, glutathione, isoflavones, Tea Polyphenols, vitamin E adds in the above-mentioned filtrate, and stirring fully dissolves it, take by weighing a certain amount of sucrose and citric acid by prescription then, the filtrate mouthfeel is adjusted, filtered once more after the adjustment, use the pure water constant volume; Decide quantities of beverage if surpass prescription institute before the constant volume, then carry out suitably concentrated, be concentrated into fill a prescription decide quantities of beverage;
Above-mentioned filtrate is carried out high-pressure homogeneous processing, and controlled pressure is 50Mpa, and temperature is 60 ℃, homogeneous 3 times; Carry out vacuum outgas behind the homogeneous, control vacuum is 35KPa, and temperature is 35 ℃; High temperature sterilization, sterilization temperature are 120 ℃, and sterilizing time is 12s; Can, check, packing gets product;
Described prescription is to contain in every 1000ml beverage:
Red date 30g, black fungus 10g, Chinese yam 20g, American Ginseng 2g, fruit of Chinese wolfberry 10g, Radix Astragali 20g, rhodiola root 10g, grape seed extract 600mg, Pine Bark 50mg, glutathione 300mg, isoflavones 150mg, Tea Polyphenols 120mg, vitamin E 25mg, sucrose 18g, citric acid 12g, surplus is a pure water.
8. red jujube health drink production technology according to claim 4 is characterized in that, production technology is:
Take by weighing red date by prescription, black fungus, Chinese yam, American Ginseng, the fruit of Chinese wolfberry, the Radix Astragali, rhodiola root, the deionized water that adds 2 times of medicinal material weight, 110 ℃ of steam treatment 30min replenish amount of purified water to 5 times of medicinal material weight, under current strength 0.9A/75w, carry out ultrasonic processing 20min with the probe type ultrasonic extraction apparatus, 100 ℃ then, decoct 100min, I filters to get filtrate; After the filtration dregs of a decoction are carried out secondary and decoct, the time is 80min, and II filters to get filtrate; Filtrate I and filtrate II are merged, add the pectase of filtrate weight 8%, stir, the control temperature is 50 ℃ of enzymolysis 2.5h; Filter behind the enzymolysis, the shitosan of adding 0.6% carries out clarifying treatment in the filtrate, and the processing time is 5h, and then filters to get filtrate;
Take by weighing grape seed extract by prescription, Pine Bark, glutathione, isoflavones, Tea Polyphenols, vitamin E, add in the above-mentioned filtrate, stirring fully dissolves it, takes by weighing a certain amount of sucrose and citric acid by prescription then, and the filtrate mouthfeel is adjusted, filter once more after the adjustment, if decide quantities of beverage with surpassing prescription institute before the pure water constant volume constant volume, then carry out suitably concentrated, be concentrated into fill a prescription decide quantities of beverage;
Above-mentioned filtrate is carried out high-pressure homogeneous processing, and controlled pressure is 50Mpa, and temperature is 65 ℃, homogeneous 2 times; Carry out vacuum outgas behind the homogeneous, control vacuum is 35KPa, and temperature is 40 ℃; High temperature sterilization, sterilization temperature are 120 ℃, and sterilizing time is 12s; Can, check, packing gets product;
Described prescription is to contain in every 1000L beverage:
Red date 30kg, black fungus 8kg, Chinese yam 20kg, American Ginseng 3kg, fruit of Chinese wolfberry 15kg, Radix Astragali 15kg, rhodiola root 10kg, grape seed extract 600g, Pine Bark 50g, glutathione 300g, isoflavones 200g, Tea Polyphenols 180g, vitamin E 30g, sucrose 15kg, citric acid 10kg, surplus is a pure water.
9. the red jujube health drink with functions of removing chloasma effect is characterized in that, makes according to the arbitrary described technology of claim 4～8.
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| CN102488262A (en) * | 2011-11-22 | 2012-06-13 | 杨军 | Manufacturing method of beverage for strengthening immunities of children |
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| CN102488262A (en) * | 2011-11-22 | 2012-06-13 | 杨军 | Manufacturing method of beverage for strengthening immunities of children |
| CN102511879A (en) * | 2011-12-29 | 2012-06-27 | 山西汉波食品股份有限公司 | Thickened red jujube guiling jelly pulp |
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| CN104012839A (en) * | 2014-05-19 | 2014-09-03 | 中国人民解放军军事医学科学院基础医学研究所 | Chitosan-polypeptide complex for preparing health products and preparation method for compound |
| CN104012839B (en) * | 2014-05-19 | 2016-04-06 | 中国人民解放军军事医学科学院基础医学研究所 | Healthcare products preparation chitosan-polypeptide complex and preparation method thereof |
| CN104606669A (en) * | 2015-03-05 | 2015-05-13 | 高霞 | Rotula for promoting skeleton development of children and preparation method of rotula |
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| CN109601982A (en) * | 2018-12-14 | 2019-04-12 | 华南理工大学 | A kind of health food and the preparation method and application thereof with eliminate chloasma function |
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Owner name: SHANXI HANBO FOOD CO., LTD. Free format text: FORMER OWNER: TAIYUAN HANBO FOODS CO., LTD. Effective date: 20120209 |
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Effective date of registration: 20120209 Address after: 030100, Shanxi Province, Yangqu County, Taiyuan Town, Huang Village, Dallas station Applicant after: Shanxi Hanbo Food Co., Ltd. Address before: 030002 Shanxi city of Taiyuan province No. 38 West Xinghualing District Applicant before: Taiyuan Hanbo Foods Co., Ltd. |
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