CN101999368A - Propiconazole-containing bactericidal composition - Google Patents
Propiconazole-containing bactericidal composition Download PDFInfo
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- CN101999368A CN101999368A CN2010105772772A CN201010577277A CN101999368A CN 101999368 A CN101999368 A CN 101999368A CN 2010105772772 A CN2010105772772 A CN 2010105772772A CN 201010577277 A CN201010577277 A CN 201010577277A CN 101999368 A CN101999368 A CN 101999368A
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- propiconazole
- cyproconazole
- penconazole
- bactericidal composition
- flutriafol
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Abstract
The invention discloses a propiconazole-containing bactericidal composition. The bactericidal composition contains components A and B, wherein A is selected from propiconazole; and B is selected from any one of the following bactericides: flutriafol, penconazole, triflumizole or cyproconazole, and the ratio of weight parts of the two active components A to B is 2-78:2-78. The bactericidal composition can be used for prevent various diseases of crops, such as powdery mildew, rust disease, leaf spot, anthracnose, and the like, and has the advantages of obvious synergistic effect, favorable safety on the crops, rain wash resistance, long-lasting pesticide effect, and the like.
Description
Technical field
The invention belongs to the agriculture chemicals fungicide field, relate to a kind of preparation and application that contains the bactericidal composition of two active components.
Background technology
Propiconazole (propiconazol), chemical name: 1-[2-(2,4 dichloro benzene base)-4-propyl group-1,3-dioxolanes-Alpha-Methyl]-1-hydrogen-1,2,4-triazole, molecular formula: C
15H
17O
2N
3Cl
2, structural formula:
Flutriafol (flutriafol), chemical name: α-(2-fluorophenyl)-α-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol, molecular formula: C
16H
13F
2N
30, Flutriafol has interior absorption, conducts in plant corpus, and disease is had protection and therapeutic action.Can prevent and treat the cereal crop powdery mildew, Helminthosporium, Puccinia, shell pin Pseudomonas pathogen also can be cooked seed treatment, prevents and treats soil-borne disease and seed-borne disease.The cereal powdery mildew there is special efficacy.
Penconazole (penconazole), chemical name: 1-[2-(2,4 dichloro benzene base)-4-propyl group-1,3-dioxolanes-2-methyl]-1-hydrogen-1,2,4-triazole, molecular formula: C
13H
15Cl
2N
3, penconazole belongs to three nitrogen heterocycles bactericide, is sterol demethylation inhibitor.Root, stem, leaf isoreactivity tissue by crop absorb, and can upwards conduct with body fluid in the plant body soon.
Fluorine bacterium azoles (triflumizole), chemical name: (E)-and 4-chloro-α, α, α-three fluoro-N-(1-imidazoles-1-base-α-third oxygen ethylidene) neighbour-toluidines fluorine bacterium azoles, molecular formula: C
15H
15N
3F
3ClO, fluorine bacterium azoles sterol demethylation inhibitor has the protection and the systemic fungicide of therapeutic action.
Cyproconazole (Cyproconazole), chemical name: 2-(4-chlorphenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl) fourth-2-alcohol, molecular formula: C
15H
18ClN
3O, cyproconazole belongs to triazole bactericidal agent.Be sterol demethylation inhibitor, have prevention and therapeutic action.All effective to the Erysiphales on cereal crop, coffee, beet, fruit tree and the grape, Uredinales, the mould genus of genus spore, Rhynchosporium spp, Septoria, Venturia bacterium.Use with other bactericide, can fine cereal eye spot disease, leaf spot and the net blotch of preventing and treating.The control wheat rust lasting period was 4～6 weeks, and preventing and treating powdery mildew was 3～4 weeks.Cereal, fruit tree and grape powdery mildew, peanut, beet tops pinta, apple scab and peanut white rot.
Summary of the invention
The long-term use of propiconazole list agent may bring degradation problem under resistance generation, the drug effect.The bactericidal composition that the present invention proposes contains two kinds of active components of A, B, and an amount of surfactant and carrier.Effective active composition A, effective active composition B percentage by weight are 2～78: 2～78.
Described a kind of bactericidal composition that contains propiconazole is characterized in that: the percentage by weight of A, two kinds of active components of B is 5～65: 5～65.
Active component A is selected from propiconazole, and active component B is Flutriafol, penconazole, fluorine bacterium azoles or cyproconazole.
The described bactericidal composition that contains propiconazole is characterized in that: the percentage by weight of propiconazole and Flutriafol is 10～35: 10～35.
The described bactericidal composition that contains propiconazole is characterized in that: the percentage by weight of propiconazole and penconazole is 10～35: 10～35.
The described bactericidal composition that contains propiconazole is characterized in that: the percentage by weight of propiconazole and fluorine bacterium azoles is 10～35: 10～35.
The described bactericidal composition that contains propiconazole is characterized in that: the percentage by weight of propiconazole and cyproconazole is 10～35: 10～35.
Amount of application when the content of active component depends on independent use in the present composition also depends on the mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target fungi.Usually active weight percentage is 0.5～90% of a gross weight in the composition, and preferable is 5%～85%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～70% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, preferably is 10～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of a total formulation weight amount, and surplus is a liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, solvent, wetting agent, thickener or the defoamer one or more.According to different dosage form, can also contain stabilizing agent known in those skilled in the art, antifreeze etc. in the preparation.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described thickener is selected from: one or more in gum Arabic, xanthans, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, the polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described emulsifier is selected from: agricultural newborn 500# (alkyl benzene calcium sulfonate), OP series phosphate (polyoxyethylene nonylphenol ether phosphate), 600# phosphate (phenyl phenol polyoxy ethyl ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, farming newborn 400# (benzyl dimethyl phenol polyoxy ethyl ether), farming newborn 600# (phenyl phenol polyoxy ethyl ether), Nongru-700 # (alkylphenol-formaldehyde resin polyoxy ethyl ether), farming newborn 36# (phenethyl fluosite polyoxy ethyl ether), farming newborn 1600# (phenethyl phenol polyoxy ethyl polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP series (polyoxyethylene nonylphenol ether), By series (castor oil polyoxyethylene ether), farming newborn 33# (alkylaryl polyoxyethylene polyoxypropylene ether), farming newborn 34# (alkylaryl polyoxyethylene poly-oxygen propylene aether), sapn series (sorbitan monostearate), tween series (sorbitan fatty acid ester APEO), in the AEO series (the pure APEO of fat) one or more.
Described solvent is selected from: N, dinethylformamide, 3-methyl cyclohexanol ketenes, N-octylpyrrolidone, N-pyrrolidones, toluene, propyl alcohol, cyclohexanone, acetone, methyl alcohol, ethanol, butanols, ethylene glycol monomethyl ether, butyl ether, ethyl acetate, vegetable oil, acetonitrile one or more.
Described stabilizing agent is selected from: one or more in BHT, triphenyl phosphite, epoxychloropropane, tributyl phosphate, triethanolamine, diethanol amine, the monoethanolamine.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by the preparation of common processing method, is about to active substance and after liquid flux or solid carrier mix, and adds in surfactant such as dispersant, stabilizing agent, wetting agent, adhesive, defoamer, stabilizing agent, the solvent etc. one or more again.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein comparatively preferably propiconazole and Flutriafol are processed into wetting powder, water dispersible granules, suspension emulsion; Propiconazole and penconazole are processed into wetting powder, water dispersible granules, suspension emulsion, aqueous emulsion, microemulsion; Propiconazole and fluorine bacterium azoles are processed into wetting powder, water dispersible granules, aqueous emulsion, microemulsion; Propiconazole and cyproconazole are processed into wetting powder, water dispersible granules, suspension emulsion, aqueous emulsion, microemulsion.
The described bactericidal composition that contains propiconazole and active component B is used for preventing and treating disease due to the germ of child Gammaproteobacteria, Basidiomycetes and Fungi Imperfecti, available and many kind of crop is for example: fruit tree, wheat, tomato, grape, vegetables and flowers and paddy rice, preventing and treating Basidiomycetes, Ascomycetes and the microbial plant disease of deuteromycetes pathogeny especially has good preventive effect to the microbial disease of basidiomycetes, imperfect fungus and ascus such as powdery mildew, fallen leaves spot disease, yellow rust, leaf spot, rust, banded sclerotial blight, anthracnose, scab etc.
Beneficial effect of the present invention: (1) is owing to the mechanism of action difference of single agent in the said composition, the problem that does not have cross resistance, so, the application of said composition can reach and delay drug-fast generation of pathogen and development, help to prolong the result of use of this medicament, reduce the purpose that pesticide resistance produces probability; (2) present composition has good synergistic effect within the specific limits, and preventive effect is higher than single agent, and dosage is little; (3) with an organic solvent dosage is few in the present invention, is difficult for producing poisoning, is convenient to transportation and storage, has improved safety, and being mixed will be lower to the influence of environment, safer; (4) present composition has enlarged fungicidal spectrum, and powdery mildew, fallen leaves spot disease, yellow rust, leaf spot, rust, banded sclerotial blight, anthracnose, scab etc. are had special efficacy.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Application Example one
Example 165% propiconazole Flutriafol wetting powder
Propiconazole 40%, Flutriafol 25%, lignosulfonates 5%, soapberry powder 2%, spaonin powder 3%, white carbon 8%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 65% propiconazole Flutriafol wetting powder.
Example 240% propiconazole Flutriafol wetting powder
Propiconazole 8%, Flutriafol 32%, lignosulfonates 4%, lauryl sodium sulfate 4%, white carbon 12%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 40% propiconazole Flutriafol wetting powder.
Example 345% propiconazole Flutriafol water dispersible granules
Propiconazole 20%, Flutriafol 25%, tea are withered 3%, lignosulfonates 3%, lauryl sodium sulfate 4%, ammonium sulfate 2%, white carbon 15%, starch 12%, diatomite add to 100%, mixed 45% propiconazole Flutriafol water dispersible granules.
Example 457% propiconazole Flutriafol water dispersible granules
Propiconazole 40%, Flutriafol 17%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 3%, polyoxyethylene carboxylate 3%, soapberry powder 4%, sodium bicarbonate 4%, white carbon 12%, starch 15%, bentonite add to 100%, the mixed 57% propiconazole Flutriafol water dispersible granules that gets.
Example 515% propiconazole Flutriafol suspension emulsion
Propiconazole 10%, Flutriafol 5%, alkylbenzenesulfonate 4%, sodium lignin sulfonate 5%, SDS 5%, xanthans 0.8%, polyethylene glycol 3%, 600# phosphate 7%, lauric acid 1%, water add to 100%, through the mixed 15% propiconazole Flutriafol suspension emulsion that gets.
Example 632% propiconazole Flutriafol suspension emulsion
Propiconazole 24%, Flutriafol 8%, alkylphenol polyoxyethylene class 3%, lignosulfonates 5%, neopelex 3%, glycerine 2%, melon glue 2%, tween series 3%, water add to 100%, the mixed 32% propiconazole Flutriafol suspension emulsion that gets.
Example 748% propiconazole Flutriafol suspension emulsion
Propiconazole 42%, Flutriafol 6%, alkyl benzene sulfonate calcium salt 5%, alkylphenol-polyethenoxy are phonetic 5%, lauryl sodium sulfate 3%, polyvinyl alcohol 2%, phosphite ester 2%, alkyl biphenyl ether disulfonic acid magnesium salts 2%, water add to 100%, mixed 48% propiconazole Flutriafol suspension emulsion.
Example 820% propiconazole penconazole wetting powder
Propiconazole 16%, penconazole 4%, alkyl benzene sulfonate calcium salt 4%, wetting and penetrating agent F 4%, white carbon 22%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 20% propiconazole penconazole wetting powder.
Example 955% propiconazole penconazole wetting powder
Propiconazole 15%, penconazole 40%, alkylaryl APEO 3%, sldium lauryl sulfate 2%, white carbon 20%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 55% propiconazole penconazole wetting powder.
Example 1025% propiconazole penconazole water dispersible granules
Propiconazole 18%, penconazole 7%, alkyl benzene sulfonate calcium salt 5%, Nekal BX 4%, citric acid 1%, starch 10%, white carbon 20%, bentonite add to 100%, the mixed 25% propiconazole penconazole water dispersible granules that gets.
Example 1160% propiconazole penconazole water dispersible granules
Propiconazole 48%, penconazole 12%, alkylphenol-polyethenoxy are phonetic 5%, DBSA 2%, calcium chloride 1%, starch 20%, diatomite add to 100%, mixed 60% propiconazole penconazole water dispersible granules.
Example 1220% propiconazole penconazole suspension emulsion
Propiconazole 16%, penconazole 4%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, ethylnaphthalene sodium sulfonate 3%, gum Arabic 2%, silicone oil 1%, polyethylene glycol 6%, agricultural newborn 500#6%, water add to 100%, the aforementioned formula material is mixed, promptly make 20% propiconazole penconazole suspension emulsion.
Example 1350% propiconazole penconazole suspension emulsion
Propiconazole 48%, penconazole 2%, neopelex 8%, ethylnaphthalene sodium sulfonate 5%, lauric acid 1%, xanthans 2%, propane diols 8%, By series 4%, water add to 100%, the aforementioned formula material is mixed, promptly make 50% propiconazole penconazole suspension emulsion.
Example 1445% propiconazole penconazole suspension emulsion
Propiconazole 10%, penconazole 35%, alkylbenzenesulfonate 3%, draw back powder 2%, polyvinyl alcohol 2%, agricultural newborn 400#8%, water and add to 100% sodium lignin sulfonate 5%, mixed 45% propiconazole penconazole suspension emulsion.
Example 1536% propiconazole penconazole microemulsion
With propiconazole 9%, penconazole 27%, propyl alcohol 10%, toluene 4%, ethylene glycol monomethyl ether 4%, ethyl acetate 4%, farming breast 34
#6%, triethanolamine salt 6%, ethylene glycol 2%, silicone oil 0.4%, deionized water supplies 100%, makes 36% propiconazole penconazole microemulsion.
Example 1650% propiconazole penconazole microemulsion
With propiconazole 2%, penconazole 48%, toluene 17%, methyl alcohol 6%, tween 4%, farming breast 600
#2%, Nongru-700
#6%, propane diols 1%, silicone oil 0.4%, deionized water are supplied 100%, 50% propiconazole penconazole microemulsion.
Example 1725% propiconazole penconazole microemulsion
With propiconazole 20%, penconazole 5%, toluene 12%, N-pyrrolidones 4%, tween 4%, farming breast 600
#3%, triethanolamine salt 5%, ethylene glycol 2%, silicone compound 0.5%, deionized water are supplied 100%, 25% propiconazole penconazole microemulsion.
Example 1835% propiconazole penconazole aqueous emulsion
With propiconazole 30%, penconazole 5%, cyclohexanone 20%, N-pyrrolidones 12%, deionization farming breast 1600
#3%, the farming breast 500
#4%, ethylene glycol 4%, polyethylene glycol 1%, silicone oil 0.4%, deionized water supplies 100%, makes 35% propiconazole penconazole aqueous emulsion.
Example 1930% propiconazole penconazole aqueous emulsion
With propiconazole 24%, penconazole 6%, acetonitrile 18%, ethyl acetate 15%, farming breast 400
#4%, 600
#Phosphate 4%, propane diols 2%, polyvinyl alcohol 1%, silicone oil 0.5%, deionized water supplies 100%, makes 30% propiconazole penconazole aqueous emulsion.
Example 2036% propiconazole penconazole aqueous emulsion
With propiconazole 24%, penconazole 12%, vegetable oil 10%, butyl ether 4%, farming breast 33
#4%, OP series 2%, glycerine 4%, polyethylene glycol 0.5%, silicone oil 0.4%, deionized water supplies 100%, makes 36% propiconazole penconazole aqueous emulsion.
Example 2130% propiconazole cyproconazole wetting powder
Propiconazole 20%, cyproconazole 10%, lignosulfonates 5%, soapberry powder 2%, spaonin powder 3%, white carbon 15%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 30% propiconazole cyproconazole wetting powder.
Example 2260% propiconazole cyproconazole wetting powder
Propiconazole 40%, cyproconazole 20%, lignosulfonates 4%, lauryl sodium sulfate 4%, white carbon 12%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 60% propiconazole cyproconazole wetting powder.
Example 2327% propiconazole cyproconazole water dispersible granules
Propiconazole 18%, cyproconazole 9%, tea are withered 3%, lignosulfonates 3%, lauryl sodium sulfate 4%, ammonium sulfate 2%, bentonite add to 100%,, mixed 27% propiconazole cyproconazole water dispersible granules.
Example 2445% propiconazole cyproconazole water dispersible granules
Propiconazole 15%, cyproconazole 30%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 3%, polyoxyethylene carboxylate 3%, soapberry powder 4%, sodium bicarbonate 4%, white carbon 8%, starch 15%, kaolin add to 100%, the mixed 45% propiconazole cyproconazole water dispersible granules that gets.
Example 2530% propiconazole cyproconazole suspension emulsion
Propiconazole 20%, cyproconazole 10%, alkylphenol polyoxyethylene 6%, lignosulfonates 8%, xanthans 2%, ethylene glycol 1%, lauric acid 2%, OP series phosphate 3%, water add to 100%, the mixed 30% propiconazole cyproconazole suspension emulsion that gets.
Example 2645% propiconazole cyproconazole suspension emulsion
Propiconazole 40%, cyproconazole 5%, ethylnaphthalene sodium sulfonate 3%, polycarboxylate 4%, starch 1%, polyethylene glycol 5%, polyalcohol 2%, Nongru-700 #4%, water add to 100%, the mixed 45% propiconazole cyproconazole suspension emulsion that gets.
Example 2748% propiconazole cyproconazole suspension emulsion
Propiconazole 38%, cyproconazole 10%, alkylphenol polyoxyethylene class 3%, lignosulfonates 5%, neopelex 3%, glycerine 2%, melon glue 2%, agricultural newborn 400#6%, water add to 100%, the mixed 48% propiconazole cyproconazole suspension emulsion that gets.
Example 2824% propiconazole cyproconazole microemulsion
Propiconazole 16%, cyproconazole 8%, ethanol 10%, N-pyrrolidones 5%, tween 4%, farming breast 600
#3%, triethanolamine salt 3%, ethylene glycol 3%, lauric acid 0.3%, deionized water are supplied 100%, 24% propiconazole cyproconazole microemulsion.
Example 2910% propiconazole cyproconazole microemulsion
Propiconazole 5%, cyproconazole 5%, ethyl acetate 10%, acetone 6%, sapn series 8%, styrene polyoxyethylene ether ammonium sulfate salt 7%, propane diols 3%, silicone oil 0.4%, deionized water are supplied 100%, 10% propiconazole cyproconazole microemulsion.
Example 3038% propiconazole cyproconazole microemulsion
Propiconazole 3%, cyproconazole 35%, ethanol 15%, acetone 5%, farming breast 400
#7%, glycerin ether 1%, sldium lauryl sulfate 2%, ethylene glycol 5%, sodium sorbate 1%, deionized water add to 100%, make 38% propiconazole cyproconazole microemulsion.
Example 3128% propiconazole cyproconazole aqueous emulsion
Propiconazole 15%, cyproconazole 13%, acetone 12%, N-octylpyrrolidone 5%, farming breast 500
#4%, OP series 2%, glycerine 4%, polyethylene glycol 0.5%, silicone oil 0.4%, deionized water supplies 100%, makes 28% propiconazole cyproconazole aqueous emulsion.
Example 3236% propiconazole cyproconazole aqueous emulsion
Propiconazole 12%, cyproconazole 24%, vegetable oil 10%, butyl ether 4%, farming breast 33
#4%, tween 4%, polyethylene glycol 0.5%, silicone oil 0.5%, deionized water supplies 100%, makes 36% propiconazole cyproconazole aqueous emulsion.
Example 3314% propiconazole cyproconazole aqueous emulsion
Propiconazole 10%, cyproconazole 4%, farming breast 500
#5%, acetone 15%, Tween 80 8%, xanthans 1%, propane diols 2%, isobutanol 2%, deionized water add to 100%, make 14% propiconazole cyproconazole aqueous emulsion.
Example 3455% propiconazole triflumizole wettable powder
Propiconazole 5%, fluorine bacterium azoles 50%, alkyl benzene sulfonate calcium salt 4%, wetting and penetrating agent F 4%, white carbon 17%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 55% propiconazole triflumizole wettable powder.
Example 3542% propiconazole triflumizole wettable powder
Propiconazole 2%, fluorine bacterium azoles 40%, alkylaryl APEO 3%, sldium lauryl sulfate 2%, white carbon 20%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 42% propiconazole triflumizole wettable powder.
Example 3630% propiconazole triflumizole water dispersant
Propiconazole 20%, fluorine bacterium azoles 10%, alkyl benzene sulfonate calcium salt 5%, Nekal BX 4%, citric acid 1%, starch 10%, white carbon 20%, bentonite add to 100%, the mixed 30% propiconazole triflumizole water dispersant that gets.
Example 3720% propiconazole triflumizole water dispersant
Propiconazole 10%, fluorine bacterium azoles 10%, alkylphenol-polyethenoxy are phonetic 5%, DBSA 2%, calcium chloride 1%, starch 20%, diatomite add to 100%, mixed 20% propiconazole triflumizole water dispersant.
Example 3826% propiconazole triflumizole microemulsion
With propiconazole 20%, fluorine bacterium azoles 6%, N, dinethylformamide 17%, methyl alcohol 8%, N-pyrrolidones 4%, tween 4%, farming breast 600
#3%, Nongru-700
#5%, propane diols 3%, silicone oil 0.4%, deionized water supplies 100%, makes 26% propiconazole triflumizole microemulsion.
Example 3928% propiconazole triflumizole microemulsion
With propiconazole 18%, fluorine bacterium azoles 10%, methyl alcohol 15%, ethyl acetate 5%, N, dinethylformamide 2%, agricultural newborn 34#6%, farming breast 600
#5%, OP series 3%, polyethylene glycol 2%, silicone oil 0.6%, deionized water supplies 100%, makes 28% propiconazole triflumizole microemulsion.
Example 4020% propiconazole triflumizole microemulsion
With propiconazole 10%, fluorine bacterium azoles 10%, ethyl acetate 10%, vegetable oil 10%, sapn series 8%, styrene polyoxyethylene ether ammonium sulfate salt 7%, propane diols 3%, silicone oil 0.4%, deionized water supplies 100%, makes 20% propiconazole triflumizole microemulsion.
Example 4145% propiconazole fluorine bacterium azoles aqueous emulsion
With propiconazole 25%, fluorine bacterium azoles 20%, cyclohexanone 20%, N-pyrrolidones 12%, triethanolamine salt 6%, agricultural newborn 34#5%, ethylene glycol 4%, polyethylene glycol 1%, silicone oil 0.4%, deionized water supplies 100%, makes 45% propiconazole fluorine bacterium azoles aqueous emulsion.
Example 4230% propiconazole fluorine bacterium azoles aqueous emulsion
With propiconazole 12%, fluorine bacterium azoles 18%, acetone 15%, ethyl acetate 15%, farming breast 400
#4%, 600
#Phosphate 4%, propane diols 4%, polyvinyl alcohol 1%, silicone oil 0.4%, deionized water supplies 100%, makes 30% propiconazole fluorine bacterium azoles aqueous emulsion.
Example 4328% propiconazole fluorine bacterium azoles aqueous emulsion
With propiconazole 14%, fluorine bacterium azoles 14%, ethanol 16%, toluene 6%, 600# phosphate 4%, tween series 4%, polyethylene glycol 0.5%, silicone compound 0.5%, deionized water supplies 100%, makes 28% propiconazole fluorine bacterium azoles aqueous emulsion.
Propiconazole and active component B (B is selected from a kind of of Flutriafol, penconazole, cyproconazole, fluorine bacterium azoles) are composite to the crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the crop germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component propiconazole and B (Flutriafol, penconazole, fluorine bacterium azoles, cyproconazole) shared ratio in combination;
A is a propiconazole;
B is a kind of in Flutriafol, penconazole, cyproconazole, the fluorine bacterium azoles.
Implementation of an application example two:
Propiconazole and Flutriafol are composite to the stripe rust of wheat Toxicity Determination
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining propiconazole, the former medicine of Flutriafol and the two different proportioning mixture through preliminary experiment.
Toxicity test result
It is as shown in the table for result of the test:
Table 1 propiconazole, Flutriafol and composite toxicity test analysis of results table thereof to stripe rust of wheat
As shown in Table 1, the EC of propiconazole, Flutriafol stripe rust of wheat
50Be respectively 2.61mg/L and 1.45mg/L.The virulence of Flutriafol is lower than the virulence of propiconazole.39: 1,24: 1,8: 1,4: 1,2: 1,1: 2,1: 4,1: 24,1: 39 synergy ratio of propiconazole and Flutriafol proportioning is respectively 1.56,1.62,1.74,1.80,2.15,1.74,1.68,1.57,1.53, illustrating that propiconazole and Flutriafol were mixed in the scope at 39: 1 to 1: 39 all shows synergistic effect, synergy ratio SR maximum when propiconazole and Flutriafol weight ratio are 2: 1 wherein, synergistic effect is the most obvious.
Implementation of an application example three
Propiconazole and penconazole are composite to the wheat powdery mildew Toxicity Determination
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining propiconazole, the former medicine of penconazole and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 2 propiconazole, penconazole and composite toxicity test analysis of results table thereof to wheat powdery mildew
As shown in Table 2, propiconazole, penconazole are to the EC of wheat powdery mildew
50Be respectively 2.54mg/L and 0.83mg/L.The virulence of penconazole is lower than the virulence of propiconazole.39: 1,24: 1,12: 1,8: 1,4: 1,1: 1,1: 4,1: 24,1: 39 synergy ratio of propiconazole and penconazole proportioning difference: 1.59,1.64,1.74,1.83,2.19,1.87,1.71,1.67,1.56, illustrating that propiconazole and penconazole were mixed in the scope at 39: 1 to 1: 39 all shows synergistic effect, synergy ratio SR maximum when propiconazole and penconazole weight ratio are 4: 1 wherein, synergistic effect is the most obvious.
Implementation of an application example four
Propiconazole and fluorine bacterium azoles are composite to the apple anthracnose Toxicity Determination
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining propiconazole, the former medicine of fluorine bacterium azoles and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 3 propiconazole, fluorine bacterium azoles and composite toxicity test analysis of results table thereof to apple anthracnose
As shown in Table 3, propiconazole, fluorine bacterium azoles are to the EC of apple anthracnose
50Be respectively 2.72mg/L and 2.35mg/L.The virulence of fluorine bacterium azoles is lower than the virulence of propiconazole.Propiconazole and 39: 1,24: 1,9: 1,3: 1,1: 1,1: 3,1: 9,1: 24,1: 39 synergy ratio of fluorine bacterium azoles proportioning difference: 1.52,1.57,1.77,1.83,2.17,1.96,1.73,1.62,1.56, illustrating that propiconazole and fluorine bacterium azoles were mixed in the scope at 39: 1 to 1: 39 all shows synergistic effect, synergy ratio SR maximum when propiconazole and fluorine bacterium azoles weight ratio are 1: 1 wherein, synergistic effect is the most obvious.
Implementation of an application example five
Propiconazole and cyproconazole are composite to the pear scab Toxicity Determination
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining propiconazole, the former medicine of cyproconazole and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 4 propiconazole, cyproconazole and composite toxicity test analysis of results table thereof to pear scab
As shown in Table 4, propiconazole, cyproconazole are to the EC of pear scab
50Be respectively 2.38mg/L and 1.21mg/L.The virulence of cyproconazole is lower than the virulence of propiconazole.39: 1,24: 1,8: 1,4: 1,2: 1,1: 2,1: 4,1: 24,1: 39 synergy ratio of propiconazole and cyproconazole proportioning is respectively 1.53,1.61,1.82,1.90,2.12,1.90,1.72,1.56,1.53, illustrating that propiconazole and cyproconazole were mixed in the scope at 39: 1 to 1: 39 all shows synergistic effect, synergy ratio SR maximum when propiconazole and cyproconazole weight ratio are 2: 1 wherein, synergistic effect is the most obvious.
Embodiment uses six propiconazoles and the Flutriafol and the composite stripe rust of wheat test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is at the Xian City, Shanxi Province Changan District, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 250 grams per liter propiconazole emulsifiable concentrates (commercial), 125 grams per liter Flutriafol suspending agents (commercial).
The preceding investigation of medicine stripe rust of wheat disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 15 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 5 propiconazole, Flutriafol and the composite stripe rust of wheat test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 5, can effectively prevent and treat stripe rust of wheat after propiconazole and Flutriafol are composite, control efficiency all is better than contrasting medicament, and the lasting period is long.In the test scope of medication, the target crop is had no adverse effects, and wheat powdery mildew is had preventive effect preferably.
Implementation of an application example seven propiconazoles, penconazole and the composite control grape powdery mildew test of pesticide effectiveness thereof
This experimental establishment is at Shaanxi Province's Weinan City Linwei District, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 250 grams per liter propiconazole emulsifiable concentrates (commercial), 10% penconazole missible oil (commercial).
Investigation grape powdery mildew state of an illness radix, total number of sheets, the sick number of sheets and sick leaf-size class number before the medicine, in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively and calculates preventive effect in 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 6 propiconazole, penconazole and the composite control grape powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 6, can effectively prevent and treat grape powdery mildew after propiconazole and penconazole are composite and take place, control efficiency all is better than contrasting medicament, in this test scope of medication the target crop is had no adverse effects.
Embodiment uses eight propiconazoles and the fluorine bacterium azoles and the composite control apple anthracnose test of pesticide effectiveness thereof
This experimental establishment is at Shaanxi Province's Weinan City Baishui County, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 250 grams per liter propiconazole emulsifiable concentrates (commercial), 30% triflumizole wettable powder (commercial).
The preceding investigation of medicine apple anthracnose disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 15 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 7 propiconazole, fluorine bacterium azoles and the composite control apple anthracnose test of pesticide effectiveness thereof
As can be seen from Table 7, can effectively prevent and treat apple anthracnose after propiconazole and fluorine bacterium azoles are composite, control efficiency all is better than contrasting medicament, and the lasting period is long.In the test scope of medication, the target crop is had no adverse effects, and alternaria leaf spot of apple is also had preventive effect.
Implementation of an application example nine propiconazoles and cyproconazole and the composite pear scab test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in Fan Jia town, Dali County, Shaanxi Province, and test medicine is researched and developed, provided by Wei Erqi crop protection Co., Ltd, contrast medicament 250 grams per liter propiconazole emulsifiable concentrates (commercial), 40% cyproconazole wetting powder (commercial).
In the dispenser of pear scab their early stage, dispenser in per 7 days once is total to dispenser 2 times, and the investigation disease index was investigated disease index respectively in 7 days, 15 days after the 2nd dispenser before the dispenser, and the calculation correction preventive effect, and result of the test is as follows:
Table 8 propiconazole and cyproconazole and the composite pear scab test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 8, propiconazole, cyproconazole energy effectively preventing pear scab, control efficiency all is better than contrasting medicament, in the test scope of medication target crop is not had harm.
Claims (8)
1. bactericidal composition that contains propiconazole, it is characterized in that: the ratio of weight and number of A, two kinds of active components of B is 2～78: 2～78, and described A component is a propiconazole, and B is selected from Flutriafol, penconazole, fluorine bacterium azoles or cyproconazole.
2. the bactericidal composition that contains propiconazole according to claim 1 is characterized in that: the ratio of weight and number of A, two kinds of active components of B is 5～65: 5～65.
3. according to the described bactericidal composition that contains propiconazole of claim 2, it is characterized in that: the percentage by weight of propiconazole and Flutriafol is 10～35: 10～35.
4. according to the described bactericidal composition that contains propiconazole of claim 2, it is characterized in that: the percentage by weight of propiconazole and penconazole is 10～35: 10～35.
5. according to the described bactericidal composition that contains propiconazole of claim 2, it is characterized in that: the percentage by weight of propiconazole and fluorine bacterium azoles is 10～35: 10～35.
6. according to the described bactericidal composition that contains propiconazole of claim 2, it is characterized in that: the percentage by weight of propiconazole and cyproconazole is 10～35: 10～35.
7. the bactericidal composition that contains propiconazole according to claim 1 is characterized in that: composition is made wetting powder, water dispersible granules, suspension emulsion, microemulsion or aqueous emulsion.
8. the bactericidal composition that contains propiconazole according to claim 1 is characterized in that: bactericidal composition is used for control control basidiole Gammaproteobacteria, Ascomycetes and the microbial plant disease of deuteromycetes pathogeny.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104872140A (en) * | 2015-04-07 | 2015-09-02 | 河南中天恒信生物化学科技有限公司 | Wheat paddock composite bactericide containing flusilazole, propiconazole and azoxystrobin, and application thereof |
| CN110622963A (en) * | 2019-09-30 | 2019-12-31 | 江苏七洲绿色化工股份有限公司 | Emulsifiable granules containing propiconazole and cyproconazole as well as preparation method and application of emulsifiable granules |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE930160A1 (en) * | 1992-03-05 | 1993-09-08 | Sandoz Ltd | Fungicidal compositions |
| CN101588718A (en) * | 2006-12-15 | 2009-11-25 | 先正达有限公司 | Formulation |
-
2010
- 2010-12-07 CN CN 201010577277 patent/CN101999368B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE930160A1 (en) * | 1992-03-05 | 1993-09-08 | Sandoz Ltd | Fungicidal compositions |
| CN101588718A (en) * | 2006-12-15 | 2009-11-25 | 先正达有限公司 | Formulation |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104872140A (en) * | 2015-04-07 | 2015-09-02 | 河南中天恒信生物化学科技有限公司 | Wheat paddock composite bactericide containing flusilazole, propiconazole and azoxystrobin, and application thereof |
| CN110622963A (en) * | 2019-09-30 | 2019-12-31 | 江苏七洲绿色化工股份有限公司 | Emulsifiable granules containing propiconazole and cyproconazole as well as preparation method and application of emulsifiable granules |
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Address after: 715500 Pucheng County of Shaanxi Province agricultural base industrial park Patentee after: Shaanxi Welch Crop Protection Co., Ltd. Address before: 710075, C, 15 floor, Jinqiao International Plaza, science and technology road, hi tech Zone, Shaanxi, Xi'an Patentee before: Shaanxi Welch Crop Protection Co., Ltd. |
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