CN101991681A - Traditional Chinese medicine for treating benign prostatic hyperplasia - Google Patents
Traditional Chinese medicine for treating benign prostatic hyperplasia Download PDFInfo
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- CN101991681A CN101991681A CN2010105429299A CN201010542929A CN101991681A CN 101991681 A CN101991681 A CN 101991681A CN 2010105429299 A CN2010105429299 A CN 2010105429299A CN 201010542929 A CN201010542929 A CN 201010542929A CN 101991681 A CN101991681 A CN 101991681A
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Abstract
Description
技术领域technical field
本发明属于治疗泌尿系统疾病的中药领域。The invention belongs to the field of traditional Chinese medicine for treating urinary system diseases.
背景技术Background technique
目前的用于治疗男性前列腺增生的中药方面,存在两个方面的不足:一是效果不够明显,二是见效比较迟缓,以致于大批前列腺增生患者因长期得不到有效药物的治疗,经常尿频、尿急、尿痛、尿无力、尿不尽,尿失禁,迁延不愈,非常痛苦,并常并发尿潴留、血尿、会阴部疼痛等症状。患者及其家属很不满意。There are two deficiencies in the current traditional Chinese medicine for treating male benign prostatic hyperplasia: one is that the effect is not obvious enough, and the other is that the effect is relatively slow, so that a large number of benign prostatic hyperplasia patients often suffer from frequent urination, Urinary urgency, painful urination, weak urination, endless urination, urinary incontinence, protracted healing, very painful, and often accompanied by symptoms such as urinary retention, hematuria, and perineal pain. Patients and their families are very dissatisfied.
针对以上提出的问题,本发明提供一种治疗前列腺增生的中药,它能解决以往此类中药效果不够明显,见效比较迟缓的问题,效果好,见效快,具有效果显著,药效确切,见效较快的优点。In view of the problems raised above, the present invention provides a traditional Chinese medicine for the treatment of benign prostatic hyperplasia, which can solve the problem that the effect of such traditional Chinese medicines is not obvious enough in the past, and the effect is relatively slow. The effect is good, the effect is fast, and the effect is remarkable. The advantage of being fast.
发明内容Contents of the invention
本发明是通过以下技术方案来实现的:The present invention is achieved through the following technical solutions:
1、一种治疗前列腺增生的中药,采用中药原料制备,配方为(按重量比):1, a kind of Chinese medicine for the treatment of prostatic hyperplasia, adopts Chinese medicine raw material to prepare, and formula is (by weight):
黄芩5-15份 当归6-18份 灵芝6-18份Scutellaria baicalensis 5-15 parts Angelica 6-18 parts Ganoderma lucidum 6-18 parts
丹参6-18份 三七3-9份 瞿麦5-15份6-18 parts of Danshen, 3-9 parts of Panax notoginseng, 5-15 parts of Qumai
栀子5-15份Gardenia 5-15 parts
这种治疗前列腺增生的中药是由下列方法制成的:This traditional Chinese medicine for benign prostatic hyperplasia is made by the following methods:
(1)按上述重量比,将灵芝用水提醇沉法提取灵芝多糖,工艺流程如下:将灵芝破碎成颗粒状,过40目筛→用1∶20的热水(95℃)浸提→浸提液减压、浓缩→用3倍体积的95%乙醇混合、静置10-12小时、离心→加75%的乙醇,沉淀多糖→烘干得灵芝多糖提取物细粉;(1) According to the above weight ratio, extract Ganoderma lucidum polysaccharides from Ganoderma lucidum with water extraction and alcohol precipitation method, the process is as follows: crush Ganoderma lucidum into granules, pass through a 40-mesh sieve → leaching with 1:20 hot water (95°C) → leaching Extract the liquid under reduced pressure, concentrate → mix with 3 times the volume of 95% ethanol, let stand for 10-12 hours, centrifuge → add 75% ethanol, precipitate polysaccharide → dry to obtain fine powder of Ganoderma lucidum polysaccharide extract;
(2)按上述重量比,将黄芩、当归、丹参、瞿麦、栀子经常规水提取工艺提取,制成提取物浸膏细粉;(2) According to the above weight ratio, Scutellaria baicalensis, Angelica sinensis, Salvia miltiorrhiza, Qumae, and Gardenia are extracted through a conventional water extraction process to make extract extract fine powder;
(3)按上述重量比,将三七研成细粉,与上述(1)、(2)两种提取物细粉混合,搅拌均匀,制成中药颗粒剂、胶囊剂、片剂。(3) According to the above weight ratio, grind Radix Notoginseng into a fine powder, mix with the fine powder of the above two kinds of extracts (1) and (2), stir evenly, and make traditional Chinese medicine granules, capsules, and tablets.
本发明根据民间传统配方,根据中医扶正培本、活血化瘀的理论,精心研制而成。方中灵芝、当归扶正培本,益气养血,增强机体免疫力;丹参、三七养血活血、化瘀止痛;辅以黄芩清热燥湿,泻火解毒;瞿麦、栀子利尿通淋,瞿麦清热通淋凉血,栀子凉血清热利尿,二者相伍为用,凉血清热通淋作用增强,用于治疗小便不通、淋漓涩痛效果卓著。诸药配伍,相得益彰,共奏扶正培本,益气养血,活血化瘀,利水消肿,渗湿通淋之功,效果好,见效快,具有效果显著,药效确切,见效较快的优点。The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. In the prescription, Ganoderma lucidum and Angelica Fuzheng Peiben can nourish qi and blood and enhance the body's immunity; Salvia miltiorrhiza and Panax notoginseng nourish blood and activate blood circulation, remove blood stasis and relieve pain; supplemented with Scutellaria baicalensis to clear away heat and dampness, purify fire and detoxify; Qumai and gardenia diuresis and relieve stranguria Qumai clears away heat, relieves stranguria and cools blood, and Gardenia jasminoides cools blood to relieve heat and diuresis. When the two are used together, the effect of cooling serum to relieve stranguria is enhanced, and it is effective in treating obstructed urination, dripping and astringent pain. All the medicines are compatible and complement each other. They play the role of strengthening the body, nourishing qi and nourishing blood, promoting blood circulation and removing blood stasis, diuresis and swelling, and eliminating dampness and treating stranguria. The effect is good and quick. advantage.
具体实施方式Detailed ways
通过以下实施方式对本发明做具体说明:The present invention is specifically described through the following embodiments:
1、取以下配方(重量按克为单位):1. Take the following formula (weight is in grams):
黄芩60克 当归70克 灵芝70克Scutellaria baicalensis 60g Angelica 70g Ganoderma lucidum 70g
丹参70克 三七30克 瞿麦60克Danshen 70g Sanqi 30g Qumai 60g
栀子60克Gardenia 60g
按规定重量,用水提醇沉法将灵芝进行提取;用常规水提取工艺将黄芩、当归、丹参、瞿麦、栀子提取,共制成提取物细粉78克,将三七研成细粉,与上述提取物细粉混合,搅拌均匀,制成细小颗粒,装入0号胶囊,制成中药胶囊385粒,每粒胶囊内含中药细粉及提取物0.28克。Extract Ganoderma lucidum by water extraction and alcohol precipitation method according to the specified weight; extract Scutellaria baicalensis, Angelica sinensis, Salvia miltiorrhiza, Qumai and Gardenia with conventional water extraction process, and make a total of 78 grams of extract fine powder, and grind Panax notoginseng into fine powder, Mix with the above extract fine powder, stir evenly, make fine particles, pack into No. 0 capsules, make 385 Chinese medicine capsules, each capsule contains Chinese medicine fine powder and 0.28 grams of extract.
2、取以下配方(重量按克为单位):2. Take the following formula (weight is in grams):
黄芩100克 当归120克 灵芝120克Scutellaria baicalensis 100g Angelica 120g Ganoderma lucidum 120g
丹参120克 三七50克 瞿麦100克Salvia 120g Sanqi 50g Qumai 100g
栀子100克Gardenia 100g
按上述同样的方法,制成中药胶囊650粒,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, make 650 Chinese medicine capsules, each capsule contains Chinese medicine fine powder and extract 0.28 gram.
3、取以下配方(重量按克为单位):3. Take the following formula (the weight is in grams):
黄芩150克 当归180克 灵芝180克Scutellaria baicalensis 150g Angelica 180g Ganoderma lucidum 180g
丹参180克 三七80克 瞿麦150克Salvia 180g Sanqi 80g Qumai 150g
栀子150克Gardenia 150g
按上述同样的方法,制成中药胶囊992粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 992 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.
4、取以下配方(按重量比):4. Take the following formula (by weight):
黄芩6份 当归7份 灵芝7份6 parts of skullcap, 7 parts of angelica, 7 parts of Ganoderma lucidum
丹参7份 三七3份 瞿麦6份7 parts of Danshen, 3 parts of Panax notoginseng, 6 parts of Qumai
栀子6份6 parts gardenia
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.
5、取以下配方(按重量比):5. Take the following formula (by weight):
黄芩12份 当归15份 灵芝15份12 parts of skullcap, 15 parts of angelica, 15 parts of Ganoderma lucidum
丹参15份 三七7份 瞿麦12份15 parts of Danshen, 7 parts of Panax notoginseng, 12 parts of Qumai
栀子12份Gardenia 12 parts
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.
临床资料:clinical information:
本发明以前列腺增生为例,经7例临床观察。选择中医诊断前列腺增生为标准:男性肢软乏力,身体虚弱,小便不畅——尿频、尿急、尿痛、尿无力、尿不尽、尿踌躇、尿潴留;临床直肠指诊,可触到增大的前列腺。如上症状,即可确诊。在确诊观察的对象中,全部为男性,无其它严重疾病,年龄为49岁-81岁,平均年龄71.2岁。The present invention takes benign prostatic hyperplasia as an example, through clinical observation of 7 cases. Choose TCM diagnosis of benign prostatic hyperplasia as the standard: male limbs are weak and weak, weak, difficulty urinating - frequent urination, urgency, painful urination, weak urination, incomplete urination, urinary hesitation, urinary retention; clinical digital rectal examination, palpable Enlarged prostate. The above symptoms can be diagnosed. Among the confirmed observation objects, all of them were male, without other serious diseases, aged from 49 to 81 years old, with an average age of 71.2 years old.
疗效判定:Judgment of curative effect:
1、显效:体质增强,身上有劲;尿频、尿急、尿痛明显缓解;尿潴留、尿踌躇、尿不尽明显减轻;直肠指诊可见前列腺增大(前列腺两侧页扩大)减轻。1. Significant effect: physical fitness is enhanced, and the body is strong; frequent urination, urgency, and painful urination are significantly relieved; urinary retention, urinary hesitation, and urinary incontinence are significantly reduced; digital rectal examination shows that the enlargement of the prostate (enlargement of both sides of the prostate) is relieved.
2、有效:体质增强,身上有劲;尿频、尿急、尿痛有所缓解;尿踌躇、尿不尽有所减轻。2. Effective: Physical fitness is strengthened, and the body is strong; frequent urination, urgency, and painful urination are relieved; urinary hesitancy and incomplete urination are relieved.
3、无效:病症无变化。3. Ineffective: no change in symptoms.
临床实验时,停服其它药物和保健营养品。服用本发明中药胶囊,观察3个月,为一个疗程。服用方法:每日2次,每次4粒胶囊,每粒胶囊内含中药细粉及提取物0.28克,饭后温开水送服,30天后症状即有缓解,服用3个月后,症状明显改善。临床实验的7人中,显效4人,有效2人,无效1人,总有效率85.7%。During the clinical trial, stop taking other medicines and health nutrition products. Take Chinese medicine capsule of the present invention, observe 3 months, be a course of treatment. Dosing method: 2 times a day, 4 capsules each time, each capsule contains 0.28g of fine powder and extract of traditional Chinese medicine, take it with warm water after meals, the symptoms will be relieved after 30 days, and the symptoms will be obvious after taking it for 3 months improve. Among the 7 people in the clinical trial, 4 people were markedly effective, 2 people were effective, and 1 person was ineffective, and the total effective rate was 85.7%.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112826881A (en) * | 2021-01-29 | 2021-05-25 | 广东德鑫制药有限公司 | A pharmaceutical composition for treating prostatic hyperplasia, and its preparation method |
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| CN1478538A (en) * | 2002-08-26 | 2004-03-03 | 上海中耀生物科技有限公司 | Chinese medicinal composition for treating prostate cancer, its preparation method and its application in the preparation of medicine for treating prostate cancer |
| CN101843804A (en) * | 2009-10-22 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating benign prostatic hyperplasiabrain |
| CN101843699A (en) * | 2009-10-16 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating benign prostatic hyperplasiabrain |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1478538A (en) * | 2002-08-26 | 2004-03-03 | 上海中耀生物科技有限公司 | Chinese medicinal composition for treating prostate cancer, its preparation method and its application in the preparation of medicine for treating prostate cancer |
| CN101843699A (en) * | 2009-10-16 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating benign prostatic hyperplasiabrain |
| CN101843804A (en) * | 2009-10-22 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating benign prostatic hyperplasiabrain |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112826881A (en) * | 2021-01-29 | 2021-05-25 | 广东德鑫制药有限公司 | A pharmaceutical composition for treating prostatic hyperplasia, and its preparation method |
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Application publication date: 20110330 |