CN101988887A - Full-automatic blood rheometer with sampling needle protecting mechanism - Google Patents
Full-automatic blood rheometer with sampling needle protecting mechanism Download PDFInfo
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- CN101988887A CN101988887A CN2009101610723A CN200910161072A CN101988887A CN 101988887 A CN101988887 A CN 101988887A CN 2009101610723 A CN2009101610723 A CN 2009101610723A CN 200910161072 A CN200910161072 A CN 200910161072A CN 101988887 A CN101988887 A CN 101988887A
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Abstract
The invention relates to a full-automatic blood rheometer with a sampling needle protecting mechanism, comprising a machine base. The machine base is provided with a sampling needle device, a stirring needle device, a rotatable-transposition sample disc device, a capillary tube viscosity measuring device, a rotary blood rheology measuring device, an automatic control circuit and a matching program. A vertical capillary tube type sampling needle is fixed on the sampling needle device, a well type protecting device is arranged on the machine base corresponding to the sampling needle and comprises a dipping tube containing the sampling needle, the top end opening of the dipping tube is communicated with an overflow liquid collecting tank, and a discharging opening is arranged at the bottom of the overflow liquid collecting tank. The sampling needle device comprises a sampling needle height regulating mechanism and a sampling needle rotary contraposition mechanism. When stopping, the sampling needle and a stirring needle extend into the dipping tube so as to prevent the sampling needle and the stirring needle from damaging or bending when the machine moves at the stopping state or due to man-made contact; in addition, the set coordinate positions of the sampling needle and the stirring needle are also protected.
Description
Technical field
The present invention relates to a kind of full-automatic hemorheology instrument that has the application of sample needle protection structure; this hemorheology instrument is provided with well formula protective device; comprise the immersion pipe that holds sample needle, the immersion pipe that holds mixing needle; prevent when off-mode moves instrument; perhaps artificial touching and cause sample needle, mixing needle damage or crooked; simultaneously, the coordinate position of also having protected sample needle, mixing needle to set.
Background technology
Chinese patent 200520104155.6 discloses a kind of fluid viscosity measurement mechanism based on the application of sample capillary pipeline, a frame is arranged, this frame is provided with the sample needle device, fix a capillary type sample needle on the described sample needle device, this sample needle is communicated with a sample-adding pump by an application of sample pipeline, on described application of sample needle body or described application of sample pipeline, a pressure transducer is set, this pressure transducer resolves processor and is electrically connected with one by data line, the described processor that resolves is electrically connected with described sample-adding pump input end by control line, below described capillary type sample needle, the sample tube fixator is set, is provided with tested liquid sample tube and test solution sample pipe in the described sample tube fixator.The utlity model has online detection, can obtain testing result, data advantage accurately and reliably immediately.This patent exists defective as follows: 1, instrument is stopped using for a long time, and sample needle is in drying regime, and the protein matter that does not wherein clean up and other foreign matters are dry and hard, thereby causes sample needle inside rough, even stops up; 2, instrument is when off-mode moves, and easy generation is artificially touched and caused sample needle to damage or bending; 3, instrument is when off-mode moves, and the coordinate position of having set might change, and influence is used next time.Therefore, need to propose a kind of new full-automatic hemorheology instrument that has the application of sample needle protection structure.
Summary of the invention
The object of the present invention is to provide a kind of full-automatic hemorheology instrument that has the application of sample needle protection structure; this hemorheology instrument is provided with well formula protective device; comprise the immersion pipe that holds sample needle, the immersion pipe that holds mixing needle; sample needle, mixing needle stretch into and soak in the pipe during instrument shutdown; sample needle, mixing needle are protected; prevent when off-mode moves instrument; perhaps artificial touching and cause sample needle, mixing needle damage or crooked; simultaneously, the coordinate position of also having protected sample needle, mixing needle to set.
The objective of the invention is to realize: a kind of full-automatic hemorheology instrument that has the application of sample needle protection structure by following technical proposals, a support is arranged, and this support is provided with sample disk device, capillary viscosity measurement mechanism, rotary blood rheology measurement device, automatic control circuit and the matcher of sample needle device, mixing needle device, rotatable transposition; Fix a vertical capillary type sample needle on the described sample needle device, be provided with well formula protective device with described sample needle correspondence position on the described support, this device comprises an immersion pipe that holds sample needle, this immersion pipe top mouth of pipe is communicated with an overflowing liquid collecting pit, and this overflowing liquid collecting pit bottom is provided with floss hole; Described sample needle device comprises sample needle height adjustment mechanism and sample needle rotation contraposition mechanism.
Compared with the prior art the present invention has following advantage:
1, the present invention adopts the immersion tubular construction that holds sample needle, when instrument is carried out cleaning procedure, sample needle is inserted into and soaks the pipe bottom, cleaning fluid injects from sample needle and soaks pipe, and constantly flow into the overflowing liquid collecting pit from soaking the pipe top mouth of pipe, both improve the cleaning performance of sample needle inwall, also improved the cleaning performance of sample needle outer wall.
2, the present invention adopts the immersion tubular construction that holds mixing needle, and when instrument was carried out cleaning procedure, mixing needle was inserted into and soaks the pipe bottom, and cleaning fluid injects and soaks pipe, and constantly flows into the overflowing liquid collecting pit from soaking the pipe top mouth of pipe, has improved the cleaning performance of mixing needle.
3, the present invention adopts the immersion tubular construction that holds sample needle, mixing needle; when instrument is in standby or off-mode; sample needle descends to being positioned at and soaks in the pipe; mixing needle descends to being positioned at and soaks in the pipe, and instrument enters guard mode, when preventing mobile instrument; perhaps artificial touching and cause sample needle damage or crooked; simultaneously, the displacement that produces does not take place not wish because of external force in the coordinate position of yet having protected sample needle, mixing needle to set.
4, since the present invention when standby or off-mode, sample needle descends to being positioned at and soaks in the pipe, use the inside and outside sample needle that soaks of cleaning fluid, all the time make sample needle keep moistening clean conditions, overcome that the protein matter that do not clean up and other foreign matters are dry and hard to cause the situation that sample needle is inner rough even stop up.
Description of drawings
The invention will be further described below in conjunction with drawings and Examples.
Fig. 1 is structural representation of the present invention (vertical view)
Fig. 2 is sectional structure synoptic diagram of the present invention (the A-A cut-open view of Fig. 1)
Fig. 3 is a sample needle apparatus structure synoptic diagram of the present invention
Fig. 4 is a sample needle apparatus structure synoptic diagram of the present invention (right view of Fig. 3)
Fig. 5 is a mixing needle apparatus structure synoptic diagram of the present invention
Fig. 6 is a mixing needle apparatus structure synoptic diagram of the present invention (right view of Fig. 5)
Fig. 7 is a pipeline structure synoptic diagram of the present invention
Embodiment
Embodiment one:
Referring to Fig. 1, Fig. 2, full-automatic hemorheology instrument of the present invention, a box support 1 is arranged, and this support is provided with sample disk device 3, capillary viscosity measurement mechanism, rotary blood rheology measurement device 5, automatic control circuit and the matcher of sample needle device 4, mixing needle device 7, rotatable transposition; Fix a vertical capillary type sample needle 401 on the described sample needle device, be provided with well formula protective device 6 with described sample needle correspondence position on the described support, this device comprises an immersion pipe that holds sample needle, this immersion pipe top mouth of pipe is communicated with an overflowing liquid collecting pit, and this overflowing liquid collecting pit bottom is provided with floss hole; Described sample needle device comprises sample needle height adjustment mechanism and sample needle rotation contraposition mechanism.
Referring to Fig. 3, Fig. 4, the sample needle device in the present embodiment comprises: top crossbearer 402, supporting upright post 403, sample needle height adjustment mechanism, sample needle rotation contraposition mechanism.Drive motor 404, synchronous belt mechanism 405, sliding track mechanism 406, crane 407 are set in the sample needle height adjustment mechanism, crane is installed on the sliding track mechanism and with synchronous belt mechanism and is connected, crane top mounting support column, the top crossbearer is installed at the supporting upright post top, and sample needle 401 is installed on the crossbearer of top.Crane can be made lifting moving along sliding track mechanism under the control of control circuit, and sample needle is done to rise or descended with the top crossbearer and moves.In the sample needle rotation contraposition mechanism drive motor 408 is set, rotates vertical pivot 409, drive motor and rotation vertical pivot are installed on the crane, rotating the vertical pivot bottom is connected with the drive motor output shaft, top and top crossbearer are in transmission connection, at the control next top of control circuit crossbearer can supporting upright post be that rotate in the axle center, makes the sample needle accurate in locating in needed working position.Described drive motor can be selected stepper motor for use.
In the present embodiment; the immersion pipe and the overflowing liquid collecting pit of sample needle well formula protective device are designed to integrative-structure; the overflowing liquid collecting pit is sleeved on and soaks pipe top; overflowing liquid collecting pit 603 is sleeved on and soaks pipe 601 outsides; overflowing liquid collecting pit bottom is provided with floss hole 604, soaks the pipe bottom and also floss hole 602 can be set, and also floss hole can be set; the purpose that floss hole is set is the emptying of being convenient to clean waste liquid, and present embodiment selects not to be provided with floss hole.It is suitable with the sample needle height to soak the pipe degree of depth, when instrument is in standby or off-mode, sample needle descends to being positioned at and soaks in the pipe, use the inside and outside sample needle that soaks of cleaning fluid, all the time make sample needle keep moistening clean conditions, overcome that the protein matter that do not clean up and other foreign matters are dry and hard to cause the situation that sample needle is inner rough even stop up.When instrument enters duty, all to clean once behind the every suction one-time detection of the sample needle sample, during cleaning, sample needle is inserted into and soaks in the pipe, cleaning fluid injects from sample needle and soaks pipe, be full of and soak Guan Houcong immersion pipe top inflow overflowing liquid collecting pit,, improved the cleaning performance of sample needle outer wall by the effluent discharge of overflowing liquid collecting pit floss hole.
When instrument was started shooting once more, sample needle carried out cleaning operation one time after finishing reset (sample needle is reset to sample needle well formula protective device top), pipe is soaked in the cleaning fluid injection of sample needle inside, soaks the cleaning fluid that retains in the pipe and is updated.
Sample needle well formula protective device characteristics are to prevent when off-mode moves instrument, perhaps artificial touching and cause sample needle damage or crooked, and simultaneously, the displacement that produces does not take place not wish because of external force in the coordinate position of yet having protected sample needle to set.
Referring to Fig. 1, Fig. 5, Fig. 6, the mixing needle device in the present embodiment comprises: oar blade type mixing needle 701, gyratory shaker structure, mixing needle height adjustment mechanism, mixing needle rotation contraposition mechanism; Be provided with well formula protective device 2 with described mixing needle correspondence position on the described support, this device comprises an immersion pipe that holds mixing needle, and this soaks the pipe top mouth of pipe and is communicated with an overflowing liquid collecting pit.Drive motor 704, synchronous belt mechanism 705, sliding track mechanism 706, crane 707 are set in the agitated height governor motion, crane is installed on the sliding track mechanism and with synchronous belt mechanism and is connected, crane top mounting support column 703, top crossbearer 702 is installed at the supporting upright post top, and mixing needle 701 is installed on the crossbearer of top.Crane can be made lifting moving along sliding track mechanism under the control of control circuit, and mixing needle is done to rise or descended with the top crossbearer and moves.In the mixing needle rotation contraposition mechanism drive motor 708 is set, rotates vertical pivot 709, drive motor and rotation vertical pivot are installed on the crane, rotating the vertical pivot bottom is connected with the drive motor output shaft, its top and top crossbearer are in transmission connection, at the control next top of control circuit crossbearer can supporting upright post be that rotate in the axle center, makes the mixing needle accurate in locating in needed working position; Drive motor 710 is set in the gyratory shaker structure, and this drive motor is arranged on the crossbearer of top, drives mixing needle forward or reverse rotation, realizes the stirring task.Described drive motor can be selected stepper motor for use.
In the present embodiment; the immersion pipe and the overflowing liquid collecting pit of mixing needle well formula protective device 2 are designed to integrative-structure; the overflowing liquid collecting pit is sleeved on and soaks pipe top; overflowing liquid collecting pit 203 is sleeved on and soaks pipe 201 outsides; overflowing liquid collecting pit bottom is provided with floss hole 204; soak the pipe bottom inlet 202 is set, the floss hole of the overflowing liquid collecting pit bottom in this inlet and the sample needle well formula protective device is communicated with, and it is suitable with the mixing needle height that the degree of depth is managed in immersion.When instrument was in standby or off-mode, mixing needle descended to being positioned at and soaks in the pipe, uses the inside and outside soaking and stirring pin of cleaning fluid, has improved the cleaning performance of mixing needle.
Mixing needle well formula protective device characteristics are to prevent when off-mode moves instrument, perhaps artificial touching and cause mixing needle damage or crooked, and simultaneously, the displacement that produces does not take place not wish because of external force in the coordinate position of yet having protected mixing needle to set.
Referring to Fig. 1, Fig. 2, the sample disk device of the rotatable transposition in the present embodiment comprises: circular sample disk 304, sample tube 303 is set in the sample disk, and turning axle 301 and drive motor 302 are set below the sample disk.Drive sample disk and rotate under the control of control circuit, the sample tube that needs are detected is transported to the detection position, and described detection position is the mixing needle or the working position of sample needle.
The function that automatic control circuit in the present embodiment is realized comprises: the control of the control of the control of sample needle adjustable height, sample needle rotation contraposition, the control of mixing needle adjustable height, mixing needle rotation stirring, mixing needle rotation contraposition control, the control of sample disk device rotation transposition, the control of capillary viscosity measurement mechanism, the control of rotary blood rheology measurement device.Comprise a computer control system in the automatic control circuit, belong to prior art, be not described in detail.
Capillary viscosity measurement mechanism in the present embodiment comprises: application of sample pipeline, sample-adding pump, pressure transducer; This pressure transducer resolves processor and is electrically connected with one by data line, and the described processor that resolves is electrically connected with described sample-adding pump input end by control line.
The more detailed structure of the related capillary viscosity measurement mechanism of present embodiment, rotary blood rheology measurement device can be with reference to China Patent No. 200510092821.3 disclosed contents, also can be with reference to the LBY-N6C fully automatic blood flow graph of selling on the market.
Comprise automatic cleaning system (belonging to the prior art category) in the full-automatic hemorheology instrument of present embodiment, referring to Fig. 7, in pipeline structure figure, cleaning fluid tank 906, strong washing lotion jar 907 provide cleaning fluid by pipeline, electric control valve 908, peristaltic pump 902 and sample needle device pipeline connection to sample needle device 4; Also comprise electric control valve 909, injection device 912 in the sample needle device pipeline.Have a positive pressure pump 904 to be communicated with rotary hemorheology measurement mechanism by pipeline, the discard solution discharge port of rotary hemorheology measurement mechanism 5 is communicated with waste collection jar 905 by pipeline, electric control valve 911, negative pressure pump 903; The overflowing liquid collecting pit floss hole of sample needle well formula protective device 6 is communicated with the immersion pipe bottom inlet of mixing needle well formula protective device 2 by pipeline, peristaltic pump 901, and its overflowing liquid collecting pit floss hole is communicated with the waste collection jar by pipeline, electric control valve 910, negative pressure pump 903.
Principle of work of the present invention is as follows:
A, the anti-freezing of collection patient venous samples can are handled in the injecting sample pipe, and this sample tube mark is handled; Normally from the about 5ml of vein venous blood samples, put into anti-coagulants in the sample tube in advance, shake up anti-freezing then, patient's numbering is marked on the sample tube;
B, use hydro-extractor make haemocyte separate fully with blood plasma to described blood sample centrifugal treating;
Sample tube after c, the centrifugal treating is put into the testing tube position of the sample disk device of described full-automatic hemorheology instrument, set the testing tube item of described sample tube, start the sample needle device, extract the plasma sample in the described sample tube, use the capillary viscosity measurement mechanism to measure described plasma sample viscosity; Again used plasma sample is recycled in the sample tube; The testing tube item of described setting sample tube is meant the residing coordinate position of above-mentioned sample tube, numbering, patient information input computing machine;
Mixing needle device in d, the described full-automatic hemorheology instrument of startup, blood sample in the described sample tube is carried out mixing, blood sample is mixed into the whole blood state, start the sample needle device and from sample tube, draw whole blood, inject described rotary hemorheology measurement mechanism, measure described whole blood sample viscosity.
E, utilization are resolved processor the data of being measured are handled, and generate to measure report.
In the above-mentioned course of work, utilize sample needle well formula protective device, mixing needle well formula protective device to clean sample needle and mixing needle at any time.
Claims (4)
1. full-automatic hemorheology instrument that has the application of sample needle protection structure, a support is arranged, and this support is provided with sample disk device, capillary viscosity measurement mechanism, rotary blood rheology measurement device, automatic control circuit and the matcher of sample needle device, mixing needle device, rotatable transposition; Fix a vertical capillary type sample needle on the described sample needle device, it is characterized in that: be provided with well formula protective device with described sample needle correspondence position on the described support, this device comprises an immersion pipe that holds sample needle, this immersion pipe top mouth of pipe is communicated with an overflowing liquid collecting pit, and this overflowing liquid collecting pit bottom is provided with floss hole; Described sample needle device comprises sample needle height adjustment mechanism and sample needle rotation contraposition mechanism.
2. full-automatic hemorheology instrument according to claim 1 is characterized in that: described mixing needle device comprises mixing needle, gyratory shaker structure, mixing needle height adjustment mechanism, mixing needle rotation contraposition mechanism; Be provided with well formula protective device with described mixing needle correspondence position on the described support, this device comprises an immersion pipe that holds mixing needle, and this immersion pipe top mouth of pipe is communicated with an overflowing liquid collecting pit, and this overflowing liquid collecting pit bottom is provided with floss hole.
3. full-automatic hemorheology instrument according to claim 1 is characterized in that: described immersion pipe bottom is provided with floss hole, and this floss hole is communicated with the waste collection jar by discharge pipe; The floss hole of described overflowing liquid collecting pit bottom is communicated with the waste collection jar by discharge pipe.
4. full-automatic hemorheology instrument according to claim 2; it is characterized in that: the described overflowing liquid collecting pit that is used for the well formula protective device of sample needle device is provided with floss hole; this floss hole is communicated with the immersion pipe bottom inlet of the well formula protective device that is used for the mixing needle device by pipeline, and the floss hole of the overflowing liquid collecting pit of this well formula protective device is communicated with the waste collection jar by discharge pipe.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009101610723A CN101988887B (en) | 2009-08-07 | 2009-08-07 | Full-automatic blood rheometer with sampling needle protecting mechanism |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009101610723A CN101988887B (en) | 2009-08-07 | 2009-08-07 | Full-automatic blood rheometer with sampling needle protecting mechanism |
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| CN101988887A true CN101988887A (en) | 2011-03-23 |
| CN101988887B CN101988887B (en) | 2012-05-30 |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103390962A (en) * | 2013-07-08 | 2013-11-13 | 宁波市鄞州欣佳电机厂 | Multifunctional double-speed series excitation motor |
| CN103710329A (en) * | 2013-12-24 | 2014-04-09 | 山西天骄食业有限公司 | Method for preparation of co-expressed recombinase with genetic engineering technology |
| CN104931460A (en) * | 2014-03-18 | 2015-09-23 | 北京泰利康信科技有限公司 | Method for improving stability of platelet aggregation index |
| CN107340172A (en) * | 2017-08-14 | 2017-11-10 | 中生（苏州）医疗科技有限公司 | A kind of integrated sample preprocessing system |
| CN108169502A (en) * | 2017-12-22 | 2018-06-15 | 深圳市普康电子有限公司 | Contained structure, the method and Biochemical Analyzer for accommodating probe |
| CN108931629A (en) * | 2012-02-07 | 2018-12-04 | 奥索临床诊断有限公司 | The situation in centrifugal blood is determined using measurement pressure |
| CN109589847A (en) * | 2018-12-26 | 2019-04-09 | 佛山科学技术学院 | A kind of multi-functional shaker |
| CN113820513A (en) * | 2021-09-18 | 2021-12-21 | 浙江盛域医疗技术有限公司 | Arm group module for sample adding |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR100533598B1 (en) * | 2003-06-24 | 2005-12-07 | (주) 세원메디텍 | Blood cell rheometer |
| CN2840922Y (en) * | 2005-08-01 | 2006-11-29 | 卢新 | Fully-automatic blood rheological instrument |
| CN1920526B (en) * | 2005-08-22 | 2012-01-11 | 北京普利生仪器有限公司 | Method and equipment for measuring fluid viscosity of capillary pipeline |
| GB0703004D0 (en) * | 2007-02-15 | 2007-03-28 | Uws Ventures Ltd | Apparatus and method for measuring rheological properties of blood |
| CN201438188U (en) * | 2009-08-07 | 2010-04-14 | 北京普利生仪器有限公司 | Sample injection needle protection device used for full-automatic blood rheometer |
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2009
- 2009-08-07 CN CN2009101610723A patent/CN101988887B/en active Active
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108931629A (en) * | 2012-02-07 | 2018-12-04 | 奥索临床诊断有限公司 | The situation in centrifugal blood is determined using measurement pressure |
| CN103390962A (en) * | 2013-07-08 | 2013-11-13 | 宁波市鄞州欣佳电机厂 | Multifunctional double-speed series excitation motor |
| CN103390962B (en) * | 2013-07-08 | 2015-11-25 | 宁波市胜源技术转移有限公司 | A kind of multi-functional double speed series excited machine |
| CN103710329A (en) * | 2013-12-24 | 2014-04-09 | 山西天骄食业有限公司 | Method for preparation of co-expressed recombinase with genetic engineering technology |
| CN104931460A (en) * | 2014-03-18 | 2015-09-23 | 北京泰利康信科技有限公司 | Method for improving stability of platelet aggregation index |
| CN107340172A (en) * | 2017-08-14 | 2017-11-10 | 中生（苏州）医疗科技有限公司 | A kind of integrated sample preprocessing system |
| CN108169502A (en) * | 2017-12-22 | 2018-06-15 | 深圳市普康电子有限公司 | Contained structure, the method and Biochemical Analyzer for accommodating probe |
| CN109589847A (en) * | 2018-12-26 | 2019-04-09 | 佛山科学技术学院 | A kind of multi-functional shaker |
| CN109589847B (en) * | 2018-12-26 | 2021-06-01 | 佛山科学技术学院 | Multifunctional oscillator |
| CN113820513A (en) * | 2021-09-18 | 2021-12-21 | 浙江盛域医疗技术有限公司 | Arm group module for sample adding |
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Address after: 102200 1st, 2nd, 4th and 5th floors, building 3, No. 18, kekeyuan Road, Life Science Park, Changping District, Beijing Patentee after: Beijing Mindray Medical Instrument Co.,Ltd. Address before: 100085 Beijing city Haidian District Qunying Science Park Building 5, two floor East Patentee before: BEIJING PRECIL INSTRUMENT Co.,Ltd. |
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