CN101961398A - Chinese medicinal oral liquid for treating cardiovascular and cerebrovascular diseases - Google Patents

Chinese medicinal oral liquid for treating cardiovascular and cerebrovascular diseases Download PDF

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Publication number
CN101961398A
CN101961398A CN2010101844485A CN201010184448A CN101961398A CN 101961398 A CN101961398 A CN 101961398A CN 2010101844485 A CN2010101844485 A CN 2010101844485A CN 201010184448 A CN201010184448 A CN 201010184448A CN 101961398 A CN101961398 A CN 101961398A
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China
Prior art keywords
oral liquid
blood
chinese medicine
radix
rhizoma chuanxiong
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CN2010101844485A
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Chinese (zh)
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周跃群
初金芝
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LIAONING ORIENTAL PHARMACEUTICAL CO Ltd
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LIAONING ORIENTAL PHARMACEUTICAL CO Ltd
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Abstract

The invention relates to Chinese medicinal oral liquid for treating cardiovascular and cerebrovascular diseases, which comprises the following raw material medicaments: Chinese angelica, peach seed, szechuan lovage rhizome and red paeony root. The Chinese medicinal oral liquid has the function of promoting blood circulation by removing blood stasis, can treat and prevent stroke and high blood viscosity syndromes.

Description

The Chinese medicine oral liquid that is used for the treatment of cardiovascular and cerebrovascular disease
Technical field
The present invention relates to a kind of Chinese medicine oral liquid that is used for the treatment of cardiovascular and cerebrovascular disease.
Background technology
The cause of disease of cardiovascular and cerebrovascular disease mainly is an arteriosclerosis, and arteriosclerosis promptly is wall thickening hardening and following the string in the arteries, makes that lumen of vessels is dwindled, blood flow is obstructed, thereby causes a series of vascular system diseases.Hyperlipidemia and angiopathy are closely related, and lipid too much on the cholesterol in the blood, triglyceride and the blood vessel wall forms the lipid peroxy material easily by free-radical oxidation, and the deposition back forms atherosclerosis on blood vessel wall.But hyperlipidemia is again a kind of stubborn disease, and the hypertensive disease of western medical treatment mainly is " captopril " and medicines such as " nitrendipines " at present, but this type of Western medicine side effect is bigger, and drug dependence is more intense, is unfavorable for taking for a long time.A lot of for this reason traditional Chinese medical science research workers are devoted to adopt Chinese medicine that this type of disease is treated.Modern Chinese medicine is divided into four types to hyperlipidemia, promptly phlegm resistance, liver and gall prefecture stagnate, the hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, the Chinese medicine of its treatment uses medicines such as Semen Cassiae, the Radix Polygoni Multiflori and Fructus Crataegi usually.Though can functions such as these medicines have blood fat reducing, invigorate blood circulation, blood pressure lowering, diuretic thoroughly cure and not recur for a long time and await further to inquire into.
Chinese patent 100490879C discloses the technology that a kind of name is called " treating hypertensive Chinese patent medicine soft gelatin capsule and preparation method ".This invention is made up of following ingredients, full toad, Fel Sus domestica, Hirudo, Agkistrodon halys, Radix Notoginseng, living Radix Salviae Miltiorrhizae, baked polygonum capitatum, Fructus Crataegi, the Radix Astragali, Herba Lycopodii, Rhizoma Chuanxiong, Rhizoma Corydalis, gold hair Fructus Lycii, Radix Adenophorae (Radix Glehniae) gram, Radix Angelicae Sinensis, Radix Ophiopogonis, Cortex Lycii, Cortex Moutan, Poria, Radix Angelicae Sinensis, the Cortex Eucommiae, Herba Dendrobii, Caulis Spatholobi, Radix Ginseng, Fructus Ligustri Lucidi, Herba Pteridis Multifidae, Radix Gentianae, Borneolum Syntheticum; Its preparation method is, medical material is worn into 120 order fine powders, makes soft gelatin capsule and is Chinese Traditional Medicines.Though some medicine has the function of alleviating hypertension symptom in this Chinese medicine composition, the composition of this Chinese medicine composition is too much, wherein the price comparison costliness of some Chinese medicine.
In addition, the name of 1179741C Granted publication is called " a kind of herbal mixture for the treatment of cerebrovascular disease " and provides another kind of solution.This kind herbal mixture is made of Radix Scutellariae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Cortex Moutan, Flos Carthami, Semen Persicae, the Radix Astragali, Radix Glycyrrhizae, Rhizoma Zingiberis Recens and Ramulus Cinnamomi.This herbal mixture is used for the treatment of cerebral anoxia ischemia, cerebral hemorrhage and senile dementia and treats disease of brain.Wherein, the Radix Scutellariae heat clearing and damp drying is used for the various disease conditions due to damp and hot, also has the effect of eliminating fire and detoxication, hemostasis; Radix Astragali tonifying Qi and lifting yang is received the antiperspirant consolidating superficial resistance, diuresis poison holding, invigorating the spleen and replenishing QI, evacuation of pus expelling pus and promoting granulation; The Cortex Moutan clearing away heat and cooling blood is used for maculae caused by violent heat pathogen, the haematemesis due to the pathogenic heat attacking blood system in febrile diseases and send out macule, bleeding due to blood-heat, and epistaxis, and leukemia, hepatocarcinoma has heat in blood, bleeding tendency; The Radix Glycyrrhizae invigorating the spleen and benefiting QI is used for the treatment of weakness of the spleen and stomach, deficiency of QI in middle-JIAO, diseases such as fatigue and weakness.As seen, this kind herbal mixture adds some and has hemostasis and invigorating the spleen and benefiting QI, and the medicine of function such as clearing away heat and cooling blood, and whether these medicines have inhibitory action to gas medicine in the blood with blood circulation promoting and blood stasis dispelling, await further to inquire into, but these medicines that added can not increase the function of Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling, and can improve its cost.
Summary of the invention
The purpose of this invention is to provide a kind of mode of utilizing blood circulation promoting and blood stasis dispelling and nourishing blood to enrich blood and treat the Chinese medicine oral liquid of cardiovascular and cerebrovascular disease.
The Chinese medicine oral liquid of the treatment cardiovascular and cerebrovascular disease that the present invention proposes comprises following raw materials by weight percent medicine: Radix Angelicae Sinensis 10-40%, Semen Persicae 10-25%, Rhizoma Chuanxiong 15-50%, Radix Paeoniae Rubra 5-30%.Wherein, the Rhizoma Chuanxiong acrid in the mouth is warm in nature, and treating blood disorders is invigorated blood circulation, and the function of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain is arranged, and can rise to fall, and has the effect of current blood vessels, promoting the circulation of QI to relieve pain.Ancient times, well-known doctor's Zhang Yuansu was called: Rhizoma Chuanxiong " the up head, the descending sea of blood ".The Li Shizhen (1518-1593 A.D.) Compendium of Material Medica is called it: " gas medicine in the blood ".Clinical each section has congestion retardance or all available its treatment of each section's pain disease of stagnation of QI and blood generally.In the side is monarch drug; Radix Angelicae Sinensis sweet in the mouth suffering is warm in nature, and Gan Wen can nourish blood and enrich blood, and the promoting blood circulation and stopping pain of again can suffering wandering away assists Rhizoma Chuanxiong that filled unobstructed, the stasis of blood of vim and vigour is stagnated to dissipate, pain disappears and be ministerial drug; The Semen Persicae bitter in the mouth is apt to into the conscience blood system, energy promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing; The Radix Paeoniae Rubra bitter cold, the master goes into Liver Channel and is apt to away blood system, has promoting blood circulation to restore menstrual flow, the dissipating blood stasis function that relieves the pain, the Fang Zhongwei adjuvant drug can be helped principal drug assistance, can increase our promoting blood circulation, removing blood stasis and relieving pain effect, this product bitter cold simultaneously again can clearing away liver-fire, to remove blood system hot and suffocating, helps Rhizoma Chuanxiong, Radix Angelicae Sinensis acrid in the mouth temperature compensation warm in nature and causes hot and suffocating anxiety so can help.
The Flos Carthami that also comprises 5-20% in the crude drug in this Chinese medicine oral liquid.Flos Carthami Xin Wentong looses, and specially goes into the Liver Channel blood system, kind can blood circulation promoting and blood stasis dispelling, the meridian dredging pain that relieves the pain, Flos Carthami be ministerial drug in the side, blood circulation promoting and blood stasis dispelling, the meridian dredging that the strengthens we effect bitterly that relieves the pain.
The percentage by weight of each crude drug is in the said composition: Radix Angelicae Sinensis 10-40%, Semen Persicae 10-25%, Radix Paeoniae Rubra 5-20%, Flos Carthami 5-20%, Rhizoma Chuanxiong 15-40%.
The Chinese medicine oral liquid of using treatment cardiovascular and cerebrovascular disease proposed by the invention is treatment premonitory apoplexy patient 491 examples clinically, wherein uses Tokyo gauge EL500 type rotation cone-plate formula viscosity apparatus in the whole blood viscosity and detects the low rate 0.5mpa.s that cuts -1Treat preceding 17.6 ± 3.1 and drop to treatment back 14.6 ± 2.4; The cerebral blood supply amount is used Kawasaki brain ultrasonic blood flow instrument QFM-1000 type and is detected cerebral blood flow by the preceding 4.9 ± 0.2ml/s of treatment, rises to 7.1 ± 0.4ml/s after the treatment; The microcirculation inspection has erythrocyte aggregation 454 examples, and 428 examples disappear after treating, and effective percentage reaches 94.27%; Clinical symptoms headache recovery from illness 375 examples account for 76.37%, and dizzy recovery from illness 279 examples account for 56.82%, observe 5 years none examples through treatment apoplexy (cerebral infarction) takes place.
Treat migraine (blood stasis headache) 64 examples simultaneously,, account for 46.9% through treatment back recovery from illness 15 examples; Produce effects 8 examples account for 25%, and effective 5 examples account for 15.6%.
The Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease proposed by the invention has the blood circulation promoting and blood stasis dispelling function, energy treatment and prevention of stroke, the thick disease of high blood viscosity; This oral liquid taking convenience.
The specific embodiment
Embodiment 1
Get Radix Angelicae Sinensis 40g, Semen Persicae 10g, Rhizoma Chuanxiong 20g, Radix Paeoniae Rubra 30g puts into container, in this container, add 0.8-1.2Kg water, preferred 1Kg water decocted preferred 1 hour then 2.5-3.5 hour, in container, add 0.6-1Kg water again after taking out supernatant, preferred 0.8Kg water decocted 1.5-2.5 hour then, preferred 2 hours taking-up supernatant, the supernatant that merges twice decoction, after filtering it is concentrated into 230-280ml, in concentrated solution, adds sodium benzoate and stir, be the Chinese medicine oral liquid of described treatment cardiovascular and cerebrovascular disease.
Embodiment 2
Get Radix Angelicae Sinensis 10g, Semen Persicae 25g, Rhizoma Chuanxiong 50g, Radix Paeoniae Rubra 15g makes the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease of the present invention according to the method for embodiment 1.
Embodiment 3
Get Radix Angelicae Sinensis 20g, Semen Persicae 15g, Rhizoma Chuanxiong 40g, Radix Paeoniae Rubra 25g makes the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease of the present invention according to the method for embodiment 1.
Embodiment 4
Get Radix Angelicae Sinensis 30g, Semen Persicae 20g, Rhizoma Chuanxiong 20g, Radix Paeoniae Rubra 30g makes the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease of the present invention according to the method for embodiment 1.
Embodiment 5
Get Radix Angelicae Sinensis 35g, Semen Persicae 13g, Rhizoma Chuanxiong 47g, Radix Paeoniae Rubra 5g makes the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease of the present invention according to the method for embodiment 1.
Embodiment 6
Get Radix Angelicae Sinensis 10g, Semen Persicae 15g, Rhizoma Chuanxiong 40g, Radix Paeoniae Rubra 20g, Flos Carthami 15g makes the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease of the present invention according to the method for embodiment 1.
Embodiment 7
Get Radix Angelicae Sinensis 40g, Semen Persicae 10g, Rhizoma Chuanxiong 15g, Radix Paeoniae Rubra 15g, Flos Carthami 20g makes the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease of the present invention according to the method for embodiment 1.
Embodiment 8
Get Radix Angelicae Sinensis, Semen Persicae, Rhizoma Chuanxiong, Radix Paeoniae Rubra, each 20g of Flos Carthami, grind to form fine powder, make the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease of the present invention according to the method for embodiment 1.
Embodiment 9
Get Radix Angelicae Sinensis 30g, Semen Persicae 25g, Rhizoma Chuanxiong 15g, Radix Paeoniae Rubra 10g, Flos Carthami 20g makes the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease of the present invention according to the method for embodiment 1.
Embodiment 10
Get Radix Angelicae Sinensis 25g, Semen Persicae 20g, Rhizoma Chuanxiong 40g, Radix Paeoniae Rubra 10g, Flos Carthami 5g makes the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease of the present invention according to the method for embodiment 1.
Embodiment 11
Get Radix Angelicae Sinensis 35g, Semen Persicae 17g, Rhizoma Chuanxiong 25g, Radix Paeoniae Rubra 13g, Flos Carthami 10g makes the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease of the present invention according to the method for embodiment 1.
The sodium benzoate that is added among the embodiment 1-11 is 7-8Kg, preferred 7-7.5Kg.
With resulting Chinese medicine oral liquid among the embodiment 1-11, the patient takes three every day, each 10ml, and the patient of cardiovascular and cerebrovascular disease takes after 30 days and can take effect.

Claims (3)

1. the Chinese medicine oral liquid of treatment cardiovascular and cerebrovascular disease is characterized in that comprising following raw materials by weight percent medicine: Radix Angelicae Sinensis 10-40%, Semen Persicae 10-25%, Rhizoma Chuanxiong 15-50%, Radix Paeoniae Rubra 5-30%.
2. Chinese medicine oral liquid according to claim 1 is characterized in that also comprising in the crude drug of said composition the Flos Carthami of 5-20%.
3. Chinese medicine oral liquid according to claim 2 is characterized in that: the percentage by weight of each crude drug is in the said composition: Radix Angelicae Sinensis 10-40%, Semen Persicae 10-25%, Flos Carthami 5-20%, Radix Paeoniae Rubra 5-20%, Rhizoma Chuanxiong 15-40%.
CN2010101844485A 2010-05-27 2010-05-27 Chinese medicinal oral liquid for treating cardiovascular and cerebrovascular diseases Pending CN101961398A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103285275A (en) * 2013-06-18 2013-09-11 冯宇伟 Medicament for preventing and treating atherosclerosis and preparation method thereof
CN103393805A (en) * 2013-07-31 2013-11-20 山东省立医院 Chinese medicinal composition
CN105054149A (en) * 2015-09-06 2015-11-18 汕头市伊家汤药品有限公司 Medicined diet soup material and preparation method thereof
CN107184818A (en) * 2017-06-15 2017-09-22 率秀冰 Blood-circulation and removing blood stasis ointment
CN111588814A (en) * 2020-06-20 2020-08-28 合肥市第三人民医院 Traditional Chinese medicine composition for treating scar uterine pregnancy and application thereof
CN113893299A (en) * 2021-10-20 2022-01-07 河南中医药大学第三附属医院 Method for treating MAS and SAS of patient suffering from apoplexy by combining liver soothing and tendon relaxing prescription with spastic muscle and application

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103285275A (en) * 2013-06-18 2013-09-11 冯宇伟 Medicament for preventing and treating atherosclerosis and preparation method thereof
CN103393805A (en) * 2013-07-31 2013-11-20 山东省立医院 Chinese medicinal composition
CN103393805B (en) * 2013-07-31 2015-01-07 山东省立医院 Chinese medicinal composition
CN105054149A (en) * 2015-09-06 2015-11-18 汕头市伊家汤药品有限公司 Medicined diet soup material and preparation method thereof
CN107184818A (en) * 2017-06-15 2017-09-22 率秀冰 Blood-circulation and removing blood stasis ointment
CN111588814A (en) * 2020-06-20 2020-08-28 合肥市第三人民医院 Traditional Chinese medicine composition for treating scar uterine pregnancy and application thereof
CN111588814B (en) * 2020-06-20 2022-05-20 合肥市第三人民医院 Traditional Chinese medicine composition for treating scar uterine pregnancy and application thereof
CN113893299A (en) * 2021-10-20 2022-01-07 河南中医药大学第三附属医院 Method for treating MAS and SAS of patient suffering from apoplexy by combining liver soothing and tendon relaxing prescription with spastic muscle and application

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Application publication date: 20110202