CN101955440A - 一种阿戈美拉汀新晶型及其制备方法 - Google Patents
一种阿戈美拉汀新晶型及其制备方法 Download PDFInfo
- Publication number
- CN101955440A CN101955440A CN 200910089360 CN200910089360A CN101955440A CN 101955440 A CN101955440 A CN 101955440A CN 200910089360 CN200910089360 CN 200910089360 CN 200910089360 A CN200910089360 A CN 200910089360A CN 101955440 A CN101955440 A CN 101955440A
- Authority
- CN
- China
- Prior art keywords
- agomelatine
- crystal
- preparation
- crystal formation
- isopropyl ether
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200910089360.2A CN101955440B (zh) | 2009-07-17 | 2009-07-17 | 一种阿戈美拉汀新晶型及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200910089360.2A CN101955440B (zh) | 2009-07-17 | 2009-07-17 | 一种阿戈美拉汀新晶型及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101955440A true CN101955440A (zh) | 2011-01-26 |
CN101955440B CN101955440B (zh) | 2014-04-09 |
Family
ID=43483061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200910089360.2A Active CN101955440B (zh) | 2009-07-17 | 2009-07-17 | 一种阿戈美拉汀新晶型及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101955440B (zh) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102050756A (zh) * | 2009-11-09 | 2011-05-11 | 北京利乐生制药科技有限公司 | 阿戈美拉汀新晶型及其制备方法 |
CN102557979A (zh) * | 2010-12-16 | 2012-07-11 | 北大方正集团有限公司 | 一种阿戈美拉汀的晶型、其制备方法、用途及药物组合物 |
CN102690209A (zh) * | 2011-03-23 | 2012-09-26 | 上海医药工业研究院 | 阿戈美拉汀的混晶(形式-ⅷ)、其制备方法、应用和包含其的药物组合物 |
WO2013021139A1 (fr) | 2011-08-10 | 2013-02-14 | Les Laboratoires Servier | Composition pharmaceutique solide pour administration buccale d'agomelatine |
WO2013082302A1 (en) | 2011-11-30 | 2013-06-06 | Ratiopharm Gmbh | Agomelatine-urea complex and crystalline forms thereof |
WO2014122405A1 (fr) | 2013-02-08 | 2014-08-14 | Les Laboratoires Servier | Composition pharmaceutique solide pour l'administration buccale d'agomélatine |
EP3075724A1 (en) | 2015-03-31 | 2016-10-05 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Solid form of agomelatine |
EP3087976A4 (en) * | 2013-12-23 | 2017-08-02 | Tianjin Taipu Pharmaceutical Science & Technology Development Co., Ltd. | Stable crystal x-form agomelatine tablet and preparation method thereof |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3466923A1 (en) * | 2017-10-09 | 2019-04-10 | KRKA, d.d., Novo mesto | Process for the preparation of agomelatine in crystalline form |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2658818B1 (fr) * | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
FR2923482B1 (fr) * | 2007-11-09 | 2010-01-29 | Servier Lab | Nouvelle forme cristalline vi de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
CN101585779B (zh) * | 2009-03-10 | 2014-04-02 | 上海医药工业研究院 | 阿戈美拉汀的晶型vi及其制备方法和应用 |
-
2009
- 2009-07-17 CN CN200910089360.2A patent/CN101955440B/zh active Active
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102050756A (zh) * | 2009-11-09 | 2011-05-11 | 北京利乐生制药科技有限公司 | 阿戈美拉汀新晶型及其制备方法 |
CN102557979A (zh) * | 2010-12-16 | 2012-07-11 | 北大方正集团有限公司 | 一种阿戈美拉汀的晶型、其制备方法、用途及药物组合物 |
CN102557979B (zh) * | 2010-12-16 | 2014-11-26 | 北大方正集团有限公司 | 一种阿戈美拉汀的晶型、其制备方法、用途及药物组合物 |
CN102690209A (zh) * | 2011-03-23 | 2012-09-26 | 上海医药工业研究院 | 阿戈美拉汀的混晶(形式-ⅷ)、其制备方法、应用和包含其的药物组合物 |
WO2012126386A1 (zh) * | 2011-03-23 | 2012-09-27 | 上海医药工业研究院 | 阿戈美拉汀的混晶(形式-ⅷ)、其制备方法、应用和包含其的药物组合物 |
EA023278B1 (ru) * | 2011-03-23 | 2016-05-31 | Шанхай Инститьют Оф Фармасьютикл Индастри | Кристаллический агомелатин (форма-viii), способ его получения, применение и содержащая его фармацевтическая композиция |
MD4484C1 (ro) * | 2011-03-23 | 2017-12-31 | Hanghai Institute Of Pharmaceutical Industry | Forma cristalină VIII a agomelatinei, procedeu de preparare, utilizarea acesteia şi compoziţie farmaceutică care o conţine |
WO2013021139A1 (fr) | 2011-08-10 | 2013-02-14 | Les Laboratoires Servier | Composition pharmaceutique solide pour administration buccale d'agomelatine |
WO2013082302A1 (en) | 2011-11-30 | 2013-06-06 | Ratiopharm Gmbh | Agomelatine-urea complex and crystalline forms thereof |
WO2014122405A1 (fr) | 2013-02-08 | 2014-08-14 | Les Laboratoires Servier | Composition pharmaceutique solide pour l'administration buccale d'agomélatine |
EP3087976A4 (en) * | 2013-12-23 | 2017-08-02 | Tianjin Taipu Pharmaceutical Science & Technology Development Co., Ltd. | Stable crystal x-form agomelatine tablet and preparation method thereof |
EP3075724A1 (en) | 2015-03-31 | 2016-10-05 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Solid form of agomelatine |
Also Published As
Publication number | Publication date |
---|---|
CN101955440B (zh) | 2014-04-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101955440B (zh) | 一种阿戈美拉汀新晶型及其制备方法 | |
CN102351857B (zh) | 盐酸托烷司琼化合物 | |
KR101536023B1 (ko) | 조합된 sert, 5-ht3 및 5-ht1a 활성을 가진 화합물의 치료 용도 | |
AU2020204286B2 (en) | Compositions comprising 2-((1-(2(4-Fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one for treating schizophrenia | |
EP2474522B1 (en) | Agomelatine and pharmaceutical compositions thereof | |
TW200800222A (en) | δ-crystalline form of Ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it | |
JP2005535698A5 (zh) | ||
TW200800221A (en) | δD-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it | |
CN112142679B (zh) | 一种吉非替尼与香草酸共晶甲醇溶剂合物及其制备方法 | |
CN102367252A (zh) | 一种盐酸托烷司琼化合物 | |
CN102219783A (zh) | 盐酸维拉佐酮及其组合物 | |
CN101805289A (zh) | 伊伐布雷定盐酸盐的ω-晶型、其制备方法和药物组合物 | |
CN110063952A (zh) | 二氢杨梅素衍生物在治疗改善睡眠中的用途 | |
WO2014056396A1 (zh) | 甲磺酸氟马替尼晶型及其制备方法和用途 | |
CN104447682A (zh) | 比拉斯汀化合物 | |
CN104447770A (zh) | 阿塞那平化合物 | |
CN111683934B (zh) | (r)-3-(1-(2,3-二氯-4-(吡嗪-2-基)苯基)-2,2,2-三氟乙基)-1-甲基-1-(1-甲基哌啶-4-基)脲的延胡索酸盐、制备方法及其用途 | |
CN101768117A (zh) | 一种盐酸伊伐布雷定新晶形及其制备方法 | |
CN102317261B (zh) | 三重再摄取抑制剂及其应用方法 | |
TW200938194A (en) | Therapeutic uses of compounds having affinity to the serotonin transporter, serotonin receptors and noradrenalin transporter | |
WO2012055163A1 (zh) | 来曲唑i型结晶及其制备方法 | |
CN101774937A (zh) | N-[2-(7-甲氧基-1-萘基)乙基]乙酰胺及其组合物 | |
WO2020011257A1 (zh) | 一种稠合三环γ-氨基酸衍生物的组合物及其制备 | |
CN112933070A (zh) | 一种激酶抑制剂及其在制备防治TrkA/B/C激酶异常活化导致疾病药物的用途 | |
CN112691102A (zh) | 黄芩素在防治帕金森病/帕金森综合征抑郁症状中的应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
ASS | Succession or assignment of patent right |
Owner name: JIANGSU AVENTIS PHARMA. CO., LTD. Free format text: FORMER OWNER: DEZHONG WANQUAN PHARMACEUTICALS TECH. DEV. CO., LTD., BEIJING Effective date: 20120530 |
|
C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 100097 HAIDIAN, BEIJING TO: 225300 TAIZHOU, JIANGSU PROVINCE |
|
TA01 | Transfer of patent application right |
Effective date of registration: 20120530 Address after: 225300 Taizhou City, Jiangsu Province medicine City Avenue, No. 1 Applicant after: Aventis Pharmaceutical (Jiangsu) Co., Ltd. Address before: 100097 Beijing city Haidian District Sijiqing Wanquan Zhuang 3 Building Applicant before: Dezhong Wanquan Pharmaceuticals Tech. Dev. Co., Ltd., Beijing |
|
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee | ||
CP01 | Change in the name or title of a patent holder |
Address after: 225300 Taizhou City, Jiangsu Province medicine City Avenue, No. 1 Patentee after: WANQUAN WANTE PHARMACEUTICAL JIANGSU CO., LTD. Address before: 225300 Taizhou City, Jiangsu Province medicine City Avenue, No. 1 Patentee before: Aventis Pharmaceutical (Jiangsu) Co., Ltd. |