CN101947136A - Miniature impact device for injuring experimental animals - Google Patents

Miniature impact device for injuring experimental animals Download PDF

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Publication number
CN101947136A
CN101947136A CN2010105129345A CN201010512934A CN101947136A CN 101947136 A CN101947136 A CN 101947136A CN 2010105129345 A CN2010105129345 A CN 2010105129345A CN 201010512934 A CN201010512934 A CN 201010512934A CN 101947136 A CN101947136 A CN 101947136A
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China
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guide
horizontal stand
impact
bump
injuring
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CN2010105129345A
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CN101947136B (en
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麻晓林
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Third Military Medical University TMMU
Third Affiliated Hospital of TMMU
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Third Affiliated Hospital of TMMU
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Abstract

The invention discloses a miniature impact device for injuring experimental animals. The device comprises a rectangular platform, an upright post and a first horizontal bracket, wherein the upright post is connected to the edge of the rectangular platform; one end of the horizontal bracket is connected to the upper part of the uptight post in a matched mode. The device is characterized in that: an upper guiding cylinder which is vertically downward is connected with the other end of the horizontal bracket in the matched mode; an impact head is arranged in the upper end part of the upper guiding cylinder; and the upper part of a lower guiding cylinder which is vertically downward is sleeved outside the lower part of the upper guiding cylinder. The miniature impact device for injuring the experimental animals has a compact structure and is light; the construction of the combined impact head can be randomly loaded or unloaded; quality data is reliable and can fully meet requirements of impact injury experimental researches; and pathologies, types and traumatic conditions of injured visceral organs are similar to those in clinic study, so that reference can be provided for clinic diagnosis, treatment and medicament experiments. The miniature impact device for injuring the experimental animals has the advantages of convenient operation, easy control of physical parameters, accurate impact parts, high repeatability and the like.

Description

A kind of small-sized percussion device that causes injury of laboratory animal
Technical field
The present invention relates to animal experiment device capable, is specifically related to a kind of small-sized percussion device that causes injury of laboratory animal.
Background technology
At present, the vertical impact machine that is used for animal impact damage experiment mainly is the biological impact machine of BIM-I type, and this impact machine is formed about 6 tons of gross weight by bump tower, buffer table and animal three parts of frame of causing injury.The bump tower is welded by angle steel, and outsourcing Radix Saposhnikoviae thin plate forms enclosed construction.The impact hammer biggest quality is 50kg, and height of drop is between 0.5~36.5m.Can trigger releasing device automatically when impact hammer is elevated to predetermined altitude, impact hammer is fallen and bump secondary hammer along the steel wire of vertically-guided.Buffer table is made up of column, buffer board and the secondary hammer of heavily about 1 ton table top, supporting bable tops, and major function is control bump amplitude and absorbs the huge energy that produces when clashing into.The maximum stroke speed of this impact machine is 26m/s, can the mimic bump moment speed of a motor vehicle be 90km/h.Animal cause injury frame can be neatly fixing animal, by adjusting, can realize accurate control to impact site and bump suppressed range to its level and vertical direction position.When implementing the animal striking experiment, control physical parameter by vertical biological impact machine controller.But because the biological impact machine of BIM-I type is a fixture, can not move,, mainly be applicable to bump large animal (dog, pig, sheep) so can only under the particular environment technical conditions, carry out bump test, the cost height, complicated operation, experiment needs many people to cooperate.Therefore, need to develop other laboratory animal percussion device.
Summary of the invention
The purpose of this invention is to provide a kind of small-sized percussion device that causes injury of laboratory animal, its volume is little, in light weight, be convenient to move, dismantle and install, easy and simple to handle, can fully be satisfied with toy, as the experiment of causing injury of the bump of head, breast, abdominal part and the extremity of rabbit, rat, mice, for clinical diagnosis, treatment and drug study provide reference frame.
A kind of small-sized percussion device that causes injury of laboratory animal of the present invention, the column, the end that comprise rectangular platform, are vertically connected on the rectangular platform edge are connected at first horizontal stand on column top, it is characterized in that:
One vertically downward last guide and the other end of first horizontal stand be connected, a bump head is located in the upper end of guide; One lateral pin passes the hole of guide one sidewall, the hole of a bump shank and the hole of last another sidewall of guide successively is positioned in the guide bump head;
One vertically downward the top of following guide is enclosed within the outside, bottom of guide, and an end of the middle part of following guide and second horizontal stand is connected, and the other end of second horizontal stand and the middle and lower part of column are connected.
Described a kind of small-sized percussion device that causes injury of laboratory animal also comprises the wooden platform that contacts with ground across four feet on rectangular platform.
Described a kind of small-sized percussion device that causes injury of laboratory animal, its described bump head is a fabricated structure, forms by the semicircle ball of a band shank with the nut that shank threads is connected; On the shank between semicircle ball and the nut, be provided with 0 or be provided with a slice quality adjustment ring at least.Like this, just can regulate the quality of bump head easily according to the experiment needs.
Described a kind of small-sized percussion device that causes injury of laboratory animal, cooperation position of the guide and first horizontal stand can up-down adjustment on it; The cooperation position of the following guide and second horizontal stand also can up-down adjustment.
Described a kind of small-sized percussion device that causes injury of laboratory animal, the cooperation position of its described first horizontal stand and second horizontal stand and column can up-down adjustment.
The present invention compares with prior art and has the following advantages:
(1) compact conformation, light, the structure of combination type bump head can load arbitrarily or off-load, qualitative data is reliable, have easy and simple to handle, physical parameter is easy to control, impact site accurately reaches advantages such as favorable repeatability;
(2), can carry out forward bump and lateral impact respectively as rabbit, rat and mice to the experiment toy.Pathology, type, the traumatic condition and clinical comparatively approaching of damage internal organs;
(3) the bump head can cause fracture of skull, brain contusion, intracranial hemorrhage etc.; Chest can cause the damage of fracture of rib, the heart, lung; The bump abdominal part when causing hepar damnification, can merge have the inclination, the damage of lung, kidney; The bump extremity can cause dissimilar fracture, can fully satisfy the needs of impact injury experimentation.
(4) can on the model of causing injury, carry out the detection of mechanics factor analysis and multinomial experimental index.
Description of drawings
Fig. 1 is a structural representation of the present invention.
Fig. 2 is the A-A view of Fig. 1.
Fig. 3 is the structural representation of combination type bump head.
The specific embodiment
The present invention is further illustrated below in conjunction with accompanying drawing.
Referring to Fig. 1, Fig. 2 and a kind of small-sized percussion device that causes injury of laboratory animal shown in Figure 3, the column 2, the end that comprise rectangular platform 1, are vertically connected on the rectangular platform edge are connected at first horizontal stand 3 on column top;
One vertically downward last guide 4 and the other end of first horizontal stand 3 be connected, a bump 5 is located in the upper end of guide 4; The hole that one lateral pin 6 passes hole, the bump hole of a shank and last another sidewall of guide of guide one sidewall successively makes clashes into 5 and is positioned in the guide 4;
One vertically downward the top of following guide 7 is enclosed within the outside, bottom of guide 4, and an end of the middle part of following guide 4 and second horizontal stand 8 is connected, and the middle and lower part of the other end of second horizontal stand and column 2 is connected;
Also comprise the wooden platform 9 that contacts with ground across four feet on rectangular platform 1.
Described bump 5 is a fabricated structure, forms by the semicircle ball 5-1 of a band shank with nut 5-2 that shank threads is connected; On the shank between semicircle ball and the nut, be provided with 0 or be provided with a slice quality adjustment ring 10 at least.Like this, just can regulate the quality of bump head easily according to the experiment needs.
The cooperation position of the last guide 4 and first horizontal stand 3 can up-down adjustment; The cooperation position of the following guide 4 and second horizontal stand 8 also can up-down adjustment.
Described first horizontal stand 3 and second horizontal stand 8 can up-down adjustment with the cooperation position of column 2.
A bump quality and guide length and height can the selected quickly and replacings according to requirement of experiment.Operation principle is to rely on the bump head from differing heights free-falling bump animal, is applicable to that head, breast, abdominal part and the extremity bump to rabbit, rat, mice caused injury.Wherein, can reach the traumatic condition requirement of impact injury according to the experiment needs by loading or off-load adjustment quality in the bullet-shaped bump head.Weight and height are can be according to requirement of experiment selected quickly and easily and change, and the animal platform of causing injury can be adjusted the animal position of causing injury arbitrarily neatly.
Now the abdominal part with the bump rabbit is an example: during experiment, earlier with rabbit anesthesia, and rabbit is placed on the abdominal part that makes rabbit on the wooden platform aims at guide down, select the quality adjustment ring to be contained on the bump head by the quality of setting again, the guide height of setting extremely adjustings in, the bump head that the quality adjustment ring will be housed with lateral pin is located by connecting on the upper end of guide, then, extract lateral pin out, make the bump head that the quality adjustment ring is housed freely fall the abdominal part of bump rabbit, promptly finish striking experiment along upper and lower guide.

Claims (5)

1. small-sized percussion device that causes injury of laboratory animal, the column (2), the end that comprise rectangular platform (1), are vertically connected on the rectangular platform edge are connected at first horizontal stand (3) on column top, it is characterized in that: vertically downward the other end of last guide (4) and first horizontal stand (3) is connected, and a bump head (5) is located in the upper end of guide (4); One lateral pin (6) passes the hole of guide one sidewall, the hole of a bump shank and the hole of last another sidewall of guide successively is positioned in the guide (4) bump head (5); One vertically downward the top of following guide (7) is enclosed within the outside, bottom of guide (4), and an end of the middle part of following guide (4) and second horizontal stand (8) is connected, and the middle and lower part of the other end of second horizontal stand and column (2) is connected.
2. a kind of small-sized percussion device that causes injury of laboratory animal according to claim 1 is characterized in that: also comprise the wooden platform (9) that contacts with ground across four feet on rectangular platform (1).
3. a kind of small-sized percussion device that causes injury of laboratory animal according to claim 1 and 2, it is characterized in that: described bump head (5) is a fabricated structure, is made up of the semicircle ball (5-1) of a band shank and the nut (5-2) that is connected with shank threads; On the shank between semicircle ball and the nut, be provided with 0 or be provided with a slice quality adjustment ring (10) at least.
4. a kind of small-sized percussion device that causes injury of laboratory animal according to claim 1 and 2 is characterized in that: the cooperation position of going up guide (4) and first horizontal stand (3) can up-down adjustment; Following guide (4) also can up-down adjustment with the cooperation position of second horizontal stand (8).
5. a kind of small-sized percussion device that causes injury of laboratory animal according to claim 1 and 2 is characterized in that: described first horizontal stand (3) and second horizontal stand (8) can up-down adjustment with the cooperation position of column (2).
CN2010105129345A 2010-10-20 2010-10-20 Miniature impact device for injuring experimental animals Expired - Fee Related CN101947136B (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103471800A (en) * 2013-09-10 2013-12-25 中国人民解放军第三军医大学第三附属医院 Portable multifunctional biology impacting machine and method for obtaining impacting energy based on same
CN103743637A (en) * 2014-01-23 2014-04-23 中国人民解放军总医院 Impact head and impactor using impact head
CN105796204A (en) * 2016-05-23 2016-07-27 戴睿武 Multifunctional experimental animal impacting machine
CN106073930A (en) * 2016-06-15 2016-11-09 中国人民解放军第三军医大学第三附属医院 Pneumatic type biological impact machine
CN108652776A (en) * 2018-05-08 2018-10-16 上海交通大学医学院附属第九人民医院 Diffuse axonal damages injury device and experimental method
CN113893057A (en) * 2021-09-30 2022-01-07 中国人民解放军陆军特色医学中心 Animal injury device capable of switching different impact means

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Publication number Priority date Publication date Assignee Title
CN101185589A (en) * 2007-12-04 2008-05-28 中山大学 Novel electric-controlled multi-use spinal cord beating device
CN101390777A (en) * 2008-10-23 2009-03-25 上海交通大学 Injury device of diffusibility axon injury experiment
CN201341952Y (en) * 2009-02-11 2009-11-11 天津医科大学总医院 Free falling type small-sized biological trauma machine
CN201414851Y (en) * 2009-06-25 2010-03-03 中国人民解放军第四军医大学 Animal closed brain injury falling body hitting device
CN101756752A (en) * 2010-01-08 2010-06-30 山西医科大学 Molding method of standardized spinal cord injury animal model

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101185589A (en) * 2007-12-04 2008-05-28 中山大学 Novel electric-controlled multi-use spinal cord beating device
CN101390777A (en) * 2008-10-23 2009-03-25 上海交通大学 Injury device of diffusibility axon injury experiment
CN201341952Y (en) * 2009-02-11 2009-11-11 天津医科大学总医院 Free falling type small-sized biological trauma machine
CN201414851Y (en) * 2009-06-25 2010-03-03 中国人民解放军第四军医大学 Animal closed brain injury falling body hitting device
CN101756752A (en) * 2010-01-08 2010-06-30 山西医科大学 Molding method of standardized spinal cord injury animal model

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103471800A (en) * 2013-09-10 2013-12-25 中国人民解放军第三军医大学第三附属医院 Portable multifunctional biology impacting machine and method for obtaining impacting energy based on same
CN103471800B (en) * 2013-09-10 2015-08-19 中国人民解放军第三军医大学第三附属医院 Portable multi-function biological impact machine and the method based on this impact machine acquisition Impact energy
CN103743637A (en) * 2014-01-23 2014-04-23 中国人民解放军总医院 Impact head and impactor using impact head
CN103743637B (en) * 2014-01-23 2016-02-03 中国人民解放军总医院 A kind of impact head and apply its ram
CN105796204A (en) * 2016-05-23 2016-07-27 戴睿武 Multifunctional experimental animal impacting machine
CN106073930A (en) * 2016-06-15 2016-11-09 中国人民解放军第三军医大学第三附属医院 Pneumatic type biological impact machine
CN106073930B (en) * 2016-06-15 2017-11-17 中国人民解放军第三军医大学第三附属医院 Pneumatic type biological impact machine
CN108652776A (en) * 2018-05-08 2018-10-16 上海交通大学医学院附属第九人民医院 Diffuse axonal damages injury device and experimental method
CN108652776B (en) * 2018-05-08 2023-12-01 上海交通大学医学院附属第九人民医院 Diffuse axonal injury device and experimental method
CN113893057A (en) * 2021-09-30 2022-01-07 中国人民解放军陆军特色医学中心 Animal injury device capable of switching different impact means
CN113893057B (en) * 2021-09-30 2023-12-01 中国人民解放军陆军特色医学中心 Animal injury device capable of switching different striking means

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