CN101926935B - Wound anti-inflammation irrigant and preparation method thereof - Google Patents
Wound anti-inflammation irrigant and preparation method thereof Download PDFInfo
- Publication number
- CN101926935B CN101926935B CN2010102474644A CN201010247464A CN101926935B CN 101926935 B CN101926935 B CN 101926935B CN 2010102474644 A CN2010102474644 A CN 2010102474644A CN 201010247464 A CN201010247464 A CN 201010247464A CN 101926935 B CN101926935 B CN 101926935B
- Authority
- CN
- China
- Prior art keywords
- wound
- herba senecionis
- parts
- irrigant
- rhizoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 206010061218 Inflammation Diseases 0.000 title abstract description 6
- 238000002360 preparation method Methods 0.000 title description 3
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 62
- 206010052428 Wound Diseases 0.000 claims abstract description 56
- 230000003467 diminishing effect Effects 0.000 claims abstract description 38
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 27
- 206010017553 Furuncle Diseases 0.000 claims abstract description 11
- 230000001737 promoting effect Effects 0.000 claims abstract description 10
- 206010048038 Wound infection Diseases 0.000 claims abstract description 9
- 206010053615 Thermal burn Diseases 0.000 claims abstract description 8
- 208000025865 Ulcer Diseases 0.000 claims abstract description 7
- 231100000397 ulcer Toxicity 0.000 claims abstract description 7
- 239000003814 drug Substances 0.000 claims description 44
- 206010054923 Inflammation of wound Diseases 0.000 claims description 37
- 238000000034 method Methods 0.000 claims description 14
- 238000004806 packaging method and process Methods 0.000 claims description 13
- 239000002985 plastic film Substances 0.000 claims description 13
- 229920006255 plastic film Polymers 0.000 claims description 13
- 230000002262 irrigation Effects 0.000 claims description 8
- 238000003973 irrigation Methods 0.000 claims description 8
- 238000009958 sewing Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 22
- 230000035876 healing Effects 0.000 abstract description 9
- 241000411851 herbal medicine Species 0.000 abstract description 8
- 238000005469 granulation Methods 0.000 abstract description 6
- 230000003179 granulation Effects 0.000 abstract description 6
- 239000002994 raw material Substances 0.000 abstract description 5
- 238000005406 washing Methods 0.000 abstract description 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 241001313857 Bletilla striata Species 0.000 abstract 1
- 241000244987 Daiswa polyphylla Species 0.000 abstract 1
- 240000003705 Senecio vulgaris Species 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 230000009194 climbing Effects 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 description 26
- 230000036407 pain Effects 0.000 description 12
- 238000002560 therapeutic procedure Methods 0.000 description 11
- 238000006243 chemical reaction Methods 0.000 description 9
- 230000003203 everyday effect Effects 0.000 description 9
- 231100000331 toxic Toxicity 0.000 description 9
- 230000002588 toxic effect Effects 0.000 description 9
- 238000011010 flushing procedure Methods 0.000 description 8
- 206010025482 malaise Diseases 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 8
- 230000006378 damage Effects 0.000 description 7
- 208000014674 injury Diseases 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 229940079593 drug Drugs 0.000 description 6
- 210000000589 cicatrix Anatomy 0.000 description 5
- 230000003340 mental effect Effects 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 238000011084 recovery Methods 0.000 description 5
- 201000004624 Dermatitis Diseases 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 238000005485 electric heating Methods 0.000 description 4
- 238000004900 laundering Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000012946 outsourcing Methods 0.000 description 4
- 238000012856 packing Methods 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 229940126534 drug product Drugs 0.000 description 3
- 230000008030 elimination Effects 0.000 description 3
- 238000003379 elimination reaction Methods 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000000825 pharmaceutical preparation Substances 0.000 description 3
- 210000000689 upper leg Anatomy 0.000 description 3
- 206010010741 Conjunctivitis Diseases 0.000 description 2
- 206010010904 Convulsion Diseases 0.000 description 2
- 206010012335 Dependence Diseases 0.000 description 2
- 240000008042 Zea mays Species 0.000 description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- 206010000269 abscess Diseases 0.000 description 2
- 201000004484 acute conjunctivitis Diseases 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000002260 anti-inflammatory agent Substances 0.000 description 2
- 229940124599 anti-inflammatory drug Drugs 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 235000005822 corn Nutrition 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 230000000474 nursing effect Effects 0.000 description 2
- 239000000955 prescription drug Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 230000000472 traumatic effect Effects 0.000 description 2
- 235000001405 Artemisia annua Nutrition 0.000 description 1
- 240000000011 Artemisia annua Species 0.000 description 1
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 206010004053 Bacterial toxaemia Diseases 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 241000201295 Euphrasia Species 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
- 208000006877 Insect Bites and Stings Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 208000032923 Lobar pneumonia Diseases 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 206010031252 Osteomyelitis Diseases 0.000 description 1
- 235000003143 Panax notoginseng Nutrition 0.000 description 1
- 241000180649 Panax notoginseng Species 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 208000028017 Psychotic disease Diseases 0.000 description 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000004078 Snake Bites Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 208000013222 Toxemia Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 230000000561 anti-psychotic effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000003429 antifungal agent Substances 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 229940124584 antitussives Drugs 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000000610 foot bone Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 235000000396 iron Nutrition 0.000 description 1
- 239000010977 jade Substances 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 208000013223 septicemia Diseases 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 239000009306 yunnan baiyao Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The wound anti-inflammation irrigant adopts scientific combination of paris polyphylla, bletilla striata, climbing groundsel herb, herba aristolochiae and borneol, is prepared from pure Chinese herbal medicines, has the advantages of easily available raw materials and convenient use, has the effects of diminishing inflammation and promoting granulation, external wound, wound infection, scald, burn, furuncle ulcer and wound external washing after suturing, and can prevent and treat wound infection and promote healing.
Description
Technical field
The present invention relates to a kind of medicine that has antibiotic, antiinflammatory, pain relieving and wound had protective effect; It specifically is the medicine of the various surgery dephlogistication and promoting nuscle growth control of being applicable to of primary raw material preparation treatment of infection with the Chinese herbal medicine.
Background technology
Existing common externally applied anti-inflammation medicine has Cidex-7, antibacterium medicine, antifungal agent, antiviral agents etc.For revive, motherland tradition tcm cause, performance state Chinese herbal medicine promotes the well-being of mankind.I use in decades, and the cflush wound plays convenient the self-care, and the proved recipe of rapid healing is served society.For this reason, to the efficient Chinese herbal medicine wound irrigation of national applications agent patent.I am village doctor, and specially psychiatry department decades are in order to succour the psychosis compatriot who wanders about as a refugee in the society and become homeless, during the last ten years; Do not know how many times to central authorities leader Premier Wen and local government's application, establishment mental patient rescue station, premier is repeatedly letters and calls answer once; For want of fund can't realize so far.In order to hold } pass and performance traditional Chinese medical science speciality, lead traditional Chinese medical science student, establish the mental patient rescue station jointly, I deliver the Chinese and western medicine antipsychotic paper that combines on the Semen Phaseoli community network of Guangxi, seek the cooperation doctor.The tide river eldest son of the emperor by his empress " be my user name, revise the envelope letter of giving the people of motherland, it is my masterpiece that the traditional Chinese medical science is not sneezed at.In order to utilize the commercial source of Chinese herbal medicine wound irrigation agent, realize ruing the mental patient rescue station well, win honors for the motherland and expect the support that can obtain relevant leader, obtain in a short time that accurate nuclear is bid to host and excellently take registration.
In recent years, in mental patient's relief, the injury that causes was on the increase, and extent of injury also continues to increase.The method of treating wound so far still has many places of going into meaning not to the utmost.Western medicine therapy mainly is to be operation stitching, the fixing treatment that is aided with antibiotic medicine again with naturopathy.The traditional Chinese medical science is main with invigorating blood circulation addiction, reducing swelling and alleviating pain then.Chinese medicine receives more limitation on wound is used.Tradition has many anti-inflammations, invigorating blood circulation addiction in the Chinese medicine, and the resources of Chinese medicinal herb that wounds such as wound healing, granulation growth, Scar eliminating medicine remove are had the Comprehensive Treatment effect is in natural drug.Like famous special product medical material one Radix Notoginseng in Yunnan, Rhizoma Paridis, solely nail, Caulis Et Folium Skimmiae etc., famous YUNNAN BAIYAO, YUNNAN HONGYAO, compound recipe Artemisia annua L. liniment etc. are also arranged, doctor among the people also with the struggle of nature in invented many effective prescriptions.On minor cut or wound, using maximum at present is various adhesive bandages, but adhesive bandage is used on the big wound and then has inconvenience, and effect is also undesirable, as be prone to when changing dressings the wound damage etc.
The employing key word is retrieved and market survey Chinese patent and authoritative website, only finds " hemostasis and anti-inflammation " relevant patent No. and does
93111078.5 93118845.8 99120020.9 96228104.2 200310104027.7 200910094568.3 200810180877.8200810140946.2 8 of hemostatic and anti-inflammatory drug patent cases are not found and Irrigant for diminishing inflammation of wound relevant report of the present invention and product.
Summary of the invention
The objective of the invention is to: according to the analysis of Chinese herbal medicine or natural drug and the research of therapy, proposing a kind of is the external Irrigant for diminishing inflammation of wound drug products of raw material with Chinese medicine.
Another purpose of the present invention is: the prescription that proposes a kind of Irrigant for diminishing inflammation of wound medicine.
Of the present invention also have a purpose to be: the method for preparing that proposes a kind of Irrigant for diminishing inflammation of wound medicine.
Of the present invention have a purpose to be again: the purposes that proposes a kind of Irrigant for diminishing inflammation of wound medicine.
Irrigant for diminishing inflammation of wound pharmaceutical formulation of the present invention is characterized in that: its prescription comprises following Chinese medicine, and Rhizoma Paridis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Senecionis Scandentis, Herba Senecionis Dianthui, Borneolum Syntheticum are formed; The well matched side's ratio of one of which is in following scope, by weight: Rhizoma Paridis 10-50 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 2-20 part, Herba Senecionis Scandentis 10-45 part, Herba Senecionis Dianthui 5-77 part, Borneolum Syntheticum 1-10 part.The preferred composition, by weight: Rhizoma Paridis 10-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-15 part, Herba Senecionis Scandentis 20-30 part, Herba Senecionis Dianthui 45-55 part, Borneolum Syntheticum 3-7 part; Preferably form 10 parts of Rhizoma Paridis, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 25 parts of Herba Senecionis Scandentiss, 50 parts of Herba Senecionis Dianthui, 5 parts of Borneolum Syntheticums again.
Irrigant for diminishing inflammation of wound drug products of the present invention is characterized in that: comprise following Chinese medicine, Rhizoma Paridis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Senecionis Scandentis, Herba Senecionis Dianthui, Borneolum Syntheticum are formed.The well matched side's ratio of one of which is in following scope, by weight: Rhizoma Paridis 10-50 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 2-20 part, Herba Senecionis Scandentis 10-45 part, Herba Senecionis Dianthui 5-77 part, Borneolum Syntheticum 1-10 part.The preferred composition, by weight: Rhizoma Paridis 10-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-15 part, Herba Senecionis Scandentis 20-30 part, Herba Senecionis Dianthui 45-55 part, Borneolum Syntheticum 3-7 part; Preferably form 10 parts of Rhizoma Paridis, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 25 parts of Herba Senecionis Scandentiss, 50 parts of Herba Senecionis Dianthui, 5 parts of Borneolum Syntheticums again.
Packing specification: can be according to different needs, the packing of decision different size; General every bag of 200g, internal layer gauze bag packing, outer with paper bag or plastic film packaging.
Function cures mainly: dephlogistication and promoting nuscle growth, pain relieving.External wound, wound infection, scald, burn, furuncle ulcer, the wound after sewing up of operating on this medicine washout, have the better prevention infection effect.
Directions for use:
Put 2 jin in clear water for every bag, need not pour out medicated powder, can connect gauze and put into pot, in the molten device such as electric cup, boiled back 10 minutes, treat the clean repeatedly wound blood stasis of temperature while hot, every day 3 times.After washing, need not wrap up wound, can not the medicament wound closure, keep ventilating.Irrigate, the back thermophilic fine laundering that must boil, former medicinal residues can add proper amount of clear water pot and boil, and use repeatedly 2 to 3 days at every turn, and the lighter can fully recover in 3 days, and heavy the wounded can fully recover in about 10 days.
This medicine adapts to earthquake, the injured treatment of colony, behind the wound suture, can nurse voluntarily, alleviates doctors and nurses's operating pressure.Remove the trouble of everyday changing dressings to hospital.Transport solution inconvenience, the traumatic patient that can not walk about.The self-care of can providing convenience, real be rapid healing, efficient economical wound irrigation agent.
Points for attention: avoid for oral administrationly, these article are the general medicines that help of wound, and the patient of major injury should combine western medical treatment, to burn, the initial stage patient that scalds, should treat cold fine laundering after medicinal liquid pot boils.
The method for preparing of Irrigant for diminishing inflammation of wound medicine of the present invention, by weight: Rhizoma Paridis 10-50 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 2-20 part, Herba Senecionis Scandentis 10-45 part, Herba Senecionis Dianthui 5-77 part, Borneolum Syntheticum 1-10 part.The preferred composition, by weight: Rhizoma Paridis 10-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-15 part, Herba Senecionis Scandentis 20-30 part, Herba Senecionis Dianthui 45-55 part, Borneolum Syntheticum 3-7 part, preferably form 10 parts of Rhizoma Paridis, 10 parts of white book boxs, 25 parts of Herba Senecionis Scandentiss, 50 parts of Herba Senecionis Dianthui, 5 parts of Borneolum Syntheticums again; Batching is pulverized, quantitatively, pack, internal layer is packed with gauze bag, and is outer with paper bag or plastic film packaging, product.
The purposes of Irrigant for diminishing inflammation of wound drug products of the present invention is mainly used in dephlogistication and promoting nuscle growth, external wound, wound infection, scald, burn, treatment sore, the wound washout after sewing up.
The function of Irrigant for diminishing inflammation of wound raw material of the present invention:
Rhizoma Paridis: its beginning of being used as medicine is stated from the medicinal root of Shennong's Herbal, and bitter in the mouth property is cooler, and is slightly poisonous, goes into Liver Channel.Function heat-clearing and toxic substances removing, reducing swelling and alleviating pain, arresting convulsion relieves dizziness, high fever, infantile convulsions, epilepsy, etc.Doctor family is many, and married woman's breast (similar acute mastitis) swells and ache, snake bite and insect sting in order to treat; Among the people then often to control laryngopharynx swelling and pain.The modern study experiment shows that the effect of Rhizoma Paridis tool antiasthmatic-antitussive to staphylococcus aureus, Hemolytic streptococcus, dysentery bacterium, Bacillus typhi, influenza virus etc., all has inhibitory action in various degree simultaneously.
The Pseudobulbus Bletillae (Rhizoma Bletillae): according to bright Li Shizhen (1518-1593 A.D.) " Compendium of Materia Medica grass one Pseudobulbus Bletillae (Rhizoma Bletillae) ": " its root white, connect and and gives birth to, so a Pseudobulbus Bletillae (Rhizoma Bletillae).Cure mainly carbuncle, malignant boil, lose cellulitis, the dead flesh of impairment of YIN, pathogen in the stomach ".
Herba Senecionis Scandentis: function cures mainly, heat clearing away, and detoxifcation, parasite killing makes eye bright.Control various acute inflammatory diseases, the wind-fire acute conjunctivitis, corneal nebula, typhoid fever, bacillary dysentery, lobar pneumonia, tonsillitis, enteritis, jaundice, influenza, toxemia, septicemia, carbuncle furuncle poison, dried exudative dermatitis skin ulcer, erysipelas, eczema is scalded trichomonal vaginitis.Be used for anemopyretic cold, conjunctival congestion and swelling pain, dysentery, skin eczema furuncle.
Herba Senecionis Dianthui: " Chinese herbal medicine is used in Tibet always " record, another name, elm Gu Xing Gaer cloth (hiding name).Herb for the feverfew Herba Senecionis Dianthui.Function cures mainly, expelling wind and removing dampness, and heat-clearing and toxic substances removing, antipruritic, control acute conjunctivitis, furuncle, dermatitis, traumatic injury.
Borneolum Syntheticum: effect, the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.
The present invention has the following advantages and effect:
Irrigant for diminishing inflammation of wound of the present invention adopts the scientific combination of Rhizoma Paridis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Senecionis Scandentis, Herba Senecionis Dianthui, Borneolum Syntheticum; Pure Chinese herbal medicine; Raw material is easy to get; Easy to use, have dephlogistication and promoting nuscle growth, analgesic effect, external wound, wound infection, scald, burn, furuncle ulcer, a wound washout after sewing up, can prevent and treat the effect that wound infection promotes healing.
The specific embodiment
Below in conjunction with test and clinical trial situation, technical scheme of the present invention is described in further detail.
Embodiment:
Irrigant for diminishing inflammation of wound of the present invention; Generally formula proportion by weight: the scope Rhizoma Paridis 10-50 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 2-20 part, Herba Senecionis Scandentis 10-45 part, Herba Senecionis Dianthui 5-77 part, Borneolum Syntheticum 1-10 part is advisable; Scope with Rhizoma Paridis 10-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-15 part, Herba Senecionis Scandentis 20-30 part, Herba Senecionis Dianthui 45-55 part, Borneolum Syntheticum 3-7 part is good; Formulate prescription in the aforementioned proportion scope, all can obtain effect preferably.9 embodiment prescriptions enumerating as follows; Each embodiment writes out a prescription through the clinical trial of 10 cases; Promptly 9 embodiment write out a prescription; The clinical trial of totally 90 cases, 5 parts of prescription drugs of 50 parts of 25 parts of 10 parts of 10 parts of Rhizoma Paridis, the Pseudobulbus Bletillae (Rhizoma Bletillae)s, Herba Senecionis Scandentiss, Herba Senecionis Dianthui, Borneolum Syntheticum of embodiment 3 wherein, most pronounced effects.
Embodiment 1
The method for preparing of Irrigant for diminishing inflammation of wound medicine of the present invention, by weight: 10 parts of Rhizoma Paridis, 2 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 10 parts of Herba Senecionis Scandentiss, 77 parts of Herba Senecionis Dianthui, 1 part of batching of Borneolum Syntheticum, pulverize; Quantitatively, pack, internal layer is packed with gauze bag; Outer with paper bag or plastic film packaging, product.
Embodiment 2
The method for preparing of Irrigant for diminishing inflammation of wound medicine of the present invention, by weight: 50 parts of Rhizoma Paridis, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 25 parts of Herba Senecionis Scandentiss, 5 parts of Herba Senecionis Dianthui, 10 parts of batchings of Borneolum Syntheticum, pulverize; Quantitatively, pack, internal layer is packed with gauze bag; Outer with paper bag or plastic film packaging, product.
Embodiment 3
The method for preparing of Irrigant for diminishing inflammation of wound medicine of the present invention, by weight: 10 parts of Rhizoma Paridis, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 25 parts of Herba Senecionis Scandentiss, 50 parts of Herba Senecionis Dianthui, 5 parts of batchings of Borneolum Syntheticum, pulverize; Quantitatively, pack, internal layer is packed with gauze bag; Outer with paper bag or plastic film packaging, product.
Embodiment 4
The method for preparing of Irrigant for diminishing inflammation of wound medicine of the present invention, by weight: 20 parts of Rhizoma Paridis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 30 parts of Herba Senecionis Scandentiss, 55 parts of Herba Senecionis Dianthui, 7 parts of batchings of Borneolum Syntheticum, pulverize; Quantitatively, pack, internal layer is packed with gauze bag; Outer with paper bag or plastic film packaging, product.
Embodiment 5
The method for preparing of Irrigant for diminishing inflammation of wound medicine of the present invention, by weight: 10 parts of Rhizoma Paridis, 5 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 20 parts of Herba Senecionis Scandentiss, 45 parts of Herba Senecionis Dianthui, 3 parts of scope batchings of Borneolum Syntheticum, pulverize; Quantitatively, pack, internal layer is packed with gauze bag; Outer with paper bag or plastic film packaging, product.
Embodiment 6
The method for preparing of the Irrigant for diminishing inflammation of wound medicine of invention, by weight: 10 parts of Rhizoma Paridis, 8 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 12 parts of Herba Senecionis Scandentiss, 65 parts of Herba Senecionis Dianthui, 5 parts of scope batchings of Borneolum Syntheticum, pulverize; Quantitatively, pack, internal layer is packed with gauze bag; Outer with paper bag or plastic film packaging, product.
Embodiment 7
The method for preparing of Irrigant for diminishing inflammation of wound medicine of the present invention, by weight: 40 parts of Rhizoma Paridis, 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Herba Senecionis Scandentiss, 20 parts of Herba Senecionis Dianthui, 5 parts of batchings of Borneolum Syntheticum, pulverize; Quantitatively, pack, internal layer is packed with gauze bag; Outer with paper bag or plastic film packaging, product.
Embodiment 8
The method for preparing of Irrigant for diminishing inflammation of wound medicine of the present invention, by weight: 20 parts of Rhizoma Paridis, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 45 parts of Herba Senecionis Scandentiss, 15 parts of Herba Senecionis Dianthui, 5 parts of batchings of Borneolum Syntheticum, pulverize; Quantitatively, pack, internal layer is packed with gauze bag; Outer with paper bag or plastic film packaging, product.
Embodiment 9
The method for preparing of Irrigant for diminishing inflammation of wound medicine of the present invention, by weight: 15 parts of Rhizoma Paridis, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 25 parts of Herba Senecionis Scandentiss, 50 parts of Herba Senecionis Dianthui, 5 parts of batchings of Borneolum Syntheticum, pulverize; Quantitatively, pack, internal layer is packed with gauze bag; Outer with paper bag or plastic film packaging, product.
Clinical trial:
In the past 20 surplus in the period of; Get above 9 formulation Example respectively; In this village clinic, Hezhou City mental patient rescue station, carried out external wound, wound infection, scald, burn, treatment sore respectively, operate on wound clinical trial after sewing up, on probation, use totally 856 examples; Clinical trial 90 examples wherein; The drug manufacture cost of embodiment 3 is moderate, most pronounced effects; Select its clinic trial, application, totally 766 examples.Any toxic and side effects, untoward reaction and malaise symptoms do not appear in the therapeutic process.
The medicine specification: every bag of 200g, the white gauze bag packing of internal layer, outer with paper bag or plastic film packaging.
Drug usage: every bag is removed outsourcing and puts 2 jin in clear water, need not pour out medicated powder, connects gauze and puts into molten devices such as electric heating cooker, boils back 10 minutes, treats that while hot temperature washes clean wound, every day 3 times repeatedly.
Therapeutic Method: the wound after the stitching, with this medicine washout; After washing, need not wrap up wound, can not the medicament wound closure, keep ventilating.Irrigate at every turn, must irrigation be boiled, after the cooling, thermophilic fine laundering, former medicinal residues can add proper amount of clear water pot and boil, and use repeatedly.
Points for attention: avoid for oral administrationly, these article are the general medicines that help of wound, and the patient of major injury should combine western medical treatment, to burn, the initial stage patient that scalds, should treat cold fine laundering after medicinal liquid pot boils.
The result: clinical trial, on probation, use totally 856 examples, wherein, the lighter's 583 examples were fully recovered in 3-5 days basically, slightly heavy the wounded's 273 examples all were almost recovered in 10-20 days; Healing back cicatrix is less, and the cicatrix that has is not obvious, does not all have recurrence wound infection person; Do not find any toxic and side effects and untoward reaction case.
This medicine adapts to earthquake, the injured treatment of colony, behind the wound suture, can nurse voluntarily, alleviates doctors and nurses's operating pressure.Remove the trouble of everyday changing dressings to hospital.Transport solution inconvenience, the traumatic patient that can not walk about.The self-care of can providing convenience, real be rapid healing, efficient economical wound irrigation agent.
Nearly section time clinical treatment case is given an example: (with the prescription drug of embodiment 3)
Case one, lotus pool horse hair end of the bridge founding iron-smelter workman, Feng XX, many hearts when coming out of the stove are sat cross-legged in meditation and are propped up at oven-fresh steel, and thigh seriously irons hinders 6 cun long wounds together, and redness, pain are unbearably.Adopt Irrigant for diminishing inflammation of wound of the present invention treatment, used two doses after, red and swollen, pain obviously alleviates, pain is eliminated, skin recovers for logotype 6 days, is almost recovered; Can go to work.Any toxic and side effects, untoward reaction and malaise symptoms do not appear in the therapeutic process.
Case two, this village tractor driver Liang Guohua my son that wounds, trousers also fray several places, right lower limb major injury 5 place's wounds; Blood. dripping, after my inspection, the foot bone is not pressed down; If be hospitalized for treatment, the minimum medical expense that will spend more than 2,000 yuan, I know that driver's family is very poor; Live several mashed watt rooms, promptly making him drive away.The onlooker asks how not make him sustain economic losses, and I say and let it pass that the doctor can do by myself.I several places wound suture of son after, use Irrigant for diminishing inflammation of wound of the present invention, the medicine of stewing in person, clean a wound, through giving meticulous treatment of a week, the healing of wound granulation promoting is good, takes out stitches at once; Continue flushing and treated ten day time, the redness of cicatrix is eliminated recovery from illness.Any toxic and side effects, untoward reaction and malaise symptoms do not appear in the therapeutic process.
Case three, spend the bit table brother of village's Buddhist towards surname Gao in vain, thigh and arm are chopped wound to the people, and hospitalize two days, because of the people who cuts him does not catch, wife was ill for a long time again, can not hand over hospitalization and medical treatment expenses, has to leave hospital.When I went to, he lied on a bed, starting must not, very important person nursing.Heavier because of its condition of the injury, I give him injection point antibiotics, clothes point antibiotic medicine, and with Irrigant for diminishing inflammation of wound treatment of the present invention, give a baby a bath on the third day after its birth inferior every day with the irrigation temperature then; Wash after 3 days, red and swollen, pain obviously alleviates, and logotype is after 15 days, and pain is eliminated, and is almost recovered; The walking of can leaving the bed, a little housework are done by group.Any toxic and side effects, untoward reaction and malaise symptoms do not appear in the therapeutic process.
The precious jade born of the same parents of Feng Jie are in case four, one in Huang Dong township, give the branch bemaul when chopping at a tree, and bleed in several places of wound, and after the hemostasis, because of being cold afternoon, hands has swollen, and adds that several places of wound skin and flesh bursts forth, and is badly mutilated.The Huang Dong commune hospital dare not connect and control.The Lian Tang commune hospital is arrived in the back, the reason of possibly coming off duty, and doctor and nurse dare to handle, and cry him to county people's hospital.Because of being left the hundreds of yuan on one's body, when delivering to my family afterwards, be eight in the evening.I check and comfort him after the wound, flesh wound; Several days all right, and I prepare Irrigant for diminishing inflammation of wound of the present invention immediately, and pot thermophilic that boils helps him to clean the wound blood stasis; With Irrigant for diminishing inflammation of wound treatment of the present invention, through giving meticulous treatment of a week, the healing of wound granulation promoting is good; Continue flushing and treated 10 day time, the redness of cicatrix is eliminated recovery from illness.Any toxic and side effects, untoward reaction and malaise symptoms do not appear in the therapeutic process.
Case five, Irrigant for diminishing inflammation of wound of the present invention, to the burn effect also fine, the old people of a Shatian surname Zhang, dress be the chemical fibre trousers; Catch fire because of carelessness, can not take off for the moment, serious burn was stayed to be cured more than 20 day in hospital; Spent several thousand yuan, handed over cost of hospitalization, had to leave hospital because of no money.Upon somebody's introduction.I am when going to treat.Patient lies in bed, thigh and pudendum serious burn, red and swollen, rotten to the corn, can't wear trousers, be covered with very important person nursing with quilt.Use Irrigant for diminishing inflammation of wound of the present invention, remove outsourcing by every bag and put 2 jin in clear water, need not pour out medicated powder, connect gauze and put into the molten device of electric heating cooker, boiled back 10 minutes, treat the clean repeatedly wound blood stasis of temperature while hot, 3 flushing treatments every day.Through giving meticulous treatment of a week, the rotten to the corn elimination, granulation promoting is good, continues flushing and has treated 10 day time, and new skin grows up to, the red and swollen elimination; Recovery from illness.Any toxic and side effects, untoward reaction and malaise symptoms do not appear in the therapeutic process.
Case six, Irrigant for diminishing inflammation of wound of the present invention, treatment furuncle ulcer effect: group yellow meaning in gulf in the Xin Lian village, left foot three place's furuncle carbuncle suppurate, and have become ulcer.Can't walk, treat the commentaries on classics of not getting better through four months western medicine and medical practitioners.I am when going, and wound stream yellow fluid has been seen the X-ray photograph of clapping, and has got rid of osteomyelitis.Interrogated ill process, promptly, told him with Irrigant for diminishing inflammation of wound treatment of the present invention; For strengthening the affected part blood circulation, the antibacterial of strengthening medicinal liquid removes the virulence degree, removes outsourcing by every bag and puts 2 jin in clear water; Need not pour out medicated powder, connect gauze and put into the molten device of electric heating cooker, boil back 10 minutes; Flushing liquor with about 40 degree washes the affected part repeatedly, washes every day 3 times; Behind the wound irrigation, must be placed on bed to foot, last insulation.The flushing treatment is after 3 days, and the furuncle abscess is controlled, and after 10 days, furuncle abscess ulcer disappears, after 15 days, and red and swollen the elimination; Recovery from illness.Any toxic and side effects, untoward reaction and malaise symptoms do not appear in the therapeutic process.
The middle aged man of seven, E Tangdan village surname He of case, son chops wound 5 cuttves by state of an illness outbreak; Head two cuttves wherein, arm back three cuttves; Arrive hospital's sutural treatment one day, bring back three days asparate infusion and oral anti-inflammatory drug, spent more than 1,300 yuan.Because of weather is hot, opened the gauze of apposition wound on the 4th day, 5 wounds are infection suppurates.Through with Irrigant for diminishing inflammation of wound treatment of the present invention, remove outsourcing by every bag and put 2 jin in clear water, need not pour out medicated powder, connect gauze and put into the molten device of electric heating cooker, boiled back 10 minutes, wash the affected part repeatedly with the flushing liquor about 40 degree, wash every day 3 times; , after 7 days give meticulous treatment, the healing of wound granulation promoting is good, takes out stitches at once; Adopt to wash every day and continue for 3 times to treat, the flushing treatment is after 10 days, and the redness of cicatrix is eliminated, recovery from illness.Any toxic and side effects, untoward reaction and malaise symptoms do not appear in the therapeutic process.
Claims (5)
1. Irrigant for diminishing inflammation of wound; It is characterized in that: form by Rhizoma Paridis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Senecionis Scandentis, Herba Senecionis Dianthui, Borneolum Syntheticum, by weight: Rhizoma Paridis 10-50 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 2-20 part, Herba Senecionis Scandentis 10-45 part, Herba Senecionis Dianthui 5-77 part, Borneolum Syntheticum 1-10 part.
2. the method for preparing of an Irrigant for diminishing inflammation of wound; It is characterized in that: by weight: the scope batching of Rhizoma Paridis 10-50 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 2-20 part, Herba Senecionis Scandentis 10-45 part, Herba Senecionis Dianthui 5-77 part, Borneolum Syntheticum 1-10 part, pulverize, quantitatively; Pack; Internal layer is packed with gauze bag, and is outer with paper bag or plastic film packaging, promptly gets.
3. Irrigant for diminishing inflammation of wound according to claim 1 is characterized in that: by weight: Rhizoma Paridis 10-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-15 part, Herba Senecionis Scandentis 20-30 part, Herba Senecionis Dianthui 45-55 part, Borneolum Syntheticum 3-7 part.
4. Irrigant for diminishing inflammation of wound according to claim 1 is characterized in that: by weight: 10 parts of Rhizoma Paridis, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 25 parts of Herba Senecionis Scandentiss, 50 parts of Herba Senecionis Dianthui, 5 parts of Borneolum Syntheticums.
5. the pharmaceutical applications of Irrigant for diminishing inflammation of wound according to claim 1 is characterized in that: said irrigation is used to prepare dephlogistication and promoting nuscle growth, external wound, wound infection, scald, burn, furuncle ulcer, the medicine of the wound washout after sewing up.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010102474644A CN101926935B (en) | 2010-08-05 | 2010-08-05 | Wound anti-inflammation irrigant and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010102474644A CN101926935B (en) | 2010-08-05 | 2010-08-05 | Wound anti-inflammation irrigant and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101926935A CN101926935A (en) | 2010-12-29 |
CN101926935B true CN101926935B (en) | 2012-05-23 |
Family
ID=43366539
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010102474644A Expired - Fee Related CN101926935B (en) | 2010-08-05 | 2010-08-05 | Wound anti-inflammation irrigant and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101926935B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103127436A (en) * | 2013-01-17 | 2013-06-05 | 武传华 | Traditional Chinese medicine composition for treating acute radioactive skin injury |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103610837B (en) * | 2013-11-25 | 2015-11-25 | 来临 | Traditional Chinese medicine liquid of control wound infection and preparation method thereof |
CN104971333A (en) * | 2015-07-10 | 2015-10-14 | 韩晓丽 | Traditional Chinese medicine for caring and cleaning of wounds |
CN109303853A (en) * | 2018-10-23 | 2019-02-05 | 柳士贤 | A kind of medicament and preparation method thereof for treating surgical wound |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1091605C (en) * | 1998-07-29 | 2002-10-02 | 刘天聪 | Markless burn ointment |
-
2010
- 2010-08-05 CN CN2010102474644A patent/CN101926935B/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103127436A (en) * | 2013-01-17 | 2013-06-05 | 武传华 | Traditional Chinese medicine composition for treating acute radioactive skin injury |
CN103127436B (en) * | 2013-01-17 | 2014-05-07 | 武传华 | Traditional Chinese medicine composition for treating acute radioactive skin injury |
Also Published As
Publication number | Publication date |
---|---|
CN101926935A (en) | 2010-12-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102133337B (en) | Externally applied medicinal liquor for treating traumatic injury | |
CN101249215B (en) | Medicine for curing burn dressing and method of preparing the same | |
CN101926935B (en) | Wound anti-inflammation irrigant and preparation method thereof | |
CN102688360B (en) | Externally-applied skin medicine for treating burn and scald | |
CN102058802A (en) | Traditional Chinese medicine composition for treating rheumatoid arthritis | |
CN103330774A (en) | Sitz bath lotion for hemorrhoid and fistula and preparation method thereof | |
CN103040916B (en) | Externally-applied skin-regenerated oily traditional Chinese medicament for treating various burns and scalds | |
CN100592917C (en) | Burned muscle reproducing oil and method of preparing the same | |
CN103393813B (en) | Pure Chinese herbal medicine preparation for treating burns and scalds as well as pyogenic infections and open traumas | |
CN101401890B (en) | External use medicament capable of effectively treating wound surface infection | |
CN103463516A (en) | Traditional Chinese medicine ointment for treating dermatophytoses and preparation method thereof | |
CN106075170A (en) | One treats phthisical Chinese medicine composition | |
CN102727698B (en) | Wound surface nursing powder for treating bedsore | |
CN101987120B (en) | Ointment for rapidly treating burn | |
CN103736025B (en) | A kind of traumatic injury SHENGFU GAO | |
CN1329068C (en) | Scarless wound healing ointment | |
CN104491808A (en) | Traditional Chinese medicine decoction for treating neck shoulder pain or lumbocrural pain | |
CN104367647B (en) | A kind of Traditional Chinese medicinal poultice combination for treating rheumatism | |
CN103948872B (en) | Traditional Chinese medicine for treating psoriatic arthritis | |
CN102283941B (en) | Crocodile emu oil scald and burn ointment and preparation method thereof | |
CN102614330A (en) | Medicinal liquor for treating rheumatic arthritis | |
CN102885943A (en) | External Chinese medicinal liniment for treating psoriasis | |
CN101292999B (en) | Plaster for treating exogenous injury | |
CN106620054A (en) | Medicine blanket for treating cervical vertebrae and production method of medicine blanket | |
CN104107251A (en) | Medicinal liquor for treating skin diseases |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120523 Termination date: 20160805 |
|
CF01 | Termination of patent right due to non-payment of annual fee |