CN101909687B - 将药物掺入弹性医疗装置相关应用的方法 - Google Patents

将药物掺入弹性医疗装置相关应用的方法 Download PDF

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Publication number
CN101909687B
CN101909687B CN200880124635.5A CN200880124635A CN101909687B CN 101909687 B CN101909687 B CN 101909687B CN 200880124635 A CN200880124635 A CN 200880124635A CN 101909687 B CN101909687 B CN 101909687B
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CN
China
Prior art keywords
drug delivery
delivery device
coating
therapeutic agent
granular particles
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Expired - Fee Related
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CN200880124635.5A
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English (en)
Chinese (zh)
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CN101909687A (zh
Inventor
D·约翰逊
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Medtronic Vascular Inc
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Medtronic Vascular Inc
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Publication date
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Publication of CN101909687A publication Critical patent/CN101909687A/zh
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Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958—Inflatable balloons for placing stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0009—Making of catheters or other medical or surgical tubes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
CN200880124635.5A 2008-01-11 2008-12-22 将药物掺入弹性医疗装置相关应用的方法 Expired - Fee Related CN101909687B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/972,790 US8070720B2 (en) 2008-01-11 2008-01-11 Methods for incorporating a drug into an elastomeric medical device
US11/972,790 2008-01-11
PCT/US2008/088001 WO2009088744A2 (en) 2008-01-11 2008-12-22 Methods for incorporating a drug into an elastomeric medical device related applications

Publications (2)

Publication Number Publication Date
CN101909687A CN101909687A (zh) 2010-12-08
CN101909687B true CN101909687B (zh) 2014-05-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880124635.5A Expired - Fee Related CN101909687B (zh) 2008-01-11 2008-12-22 将药物掺入弹性医疗装置相关应用的方法

Country Status (5)

Country Link
US (1) US8070720B2 (enExample)
EP (1) EP2234664B1 (enExample)
JP (1) JP5430580B2 (enExample)
CN (1) CN101909687B (enExample)
WO (1) WO2009088744A2 (enExample)

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US8414525B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8425459B2 (en) 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US8998846B2 (en) 2006-11-20 2015-04-07 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8414526B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
US9737640B2 (en) 2006-11-20 2017-08-22 Lutonix, Inc. Drug releasing coatings for medical devices
US20080276935A1 (en) 2006-11-20 2008-11-13 Lixiao Wang Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US8414910B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US9700704B2 (en) 2006-11-20 2017-07-11 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8430055B2 (en) 2008-08-29 2013-04-30 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
US20080175887A1 (en) 2006-11-20 2008-07-24 Lixiao Wang Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
EP3159033B1 (en) * 2008-05-01 2019-02-27 Bayer Intellectual Property GmbH Catheter balloon drug adherence techniques and methods
US8974521B2 (en) * 2011-02-24 2015-03-10 Biotronik Ag Implant and method for manufacturing same
US9956385B2 (en) * 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
CN102974026A (zh) * 2012-09-21 2013-03-20 北京美中双和医疗器械有限公司 三氧化二砷可控释放的球囊及其制备方法
US9827395B2 (en) * 2014-01-15 2017-11-28 Gyrus Acmi, Inc. Interventional sinus endoscope
US9592138B1 (en) 2015-09-13 2017-03-14 Martin Mayse Pulmonary airflow
US10293144B2 (en) * 2015-11-17 2019-05-21 Sentinent Holdings, LLC Apparatus and methods for enhanced drug delivery
CA3227157A1 (en) 2021-07-20 2023-01-26 Apreo Health, Inc. Endobronchial implants and related technology

Citations (4)

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US20020042645A1 (en) * 1996-07-03 2002-04-11 Shannon Donald T. Drug eluting radially expandable tubular stented grafts
US20050181004A1 (en) * 2003-11-10 2005-08-18 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
US6989071B2 (en) * 2001-01-30 2006-01-24 Boston Scientific Scimed, Inc. Stent with channel(s) for containing and delivering biologically active material and method for manufacturing the same
US7011654B2 (en) * 1998-04-27 2006-03-14 Artemis Medical, Inc. Dilating and support apparatus with disease inhibitors and methods for use

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US4199864A (en) * 1975-12-22 1980-04-29 Arthur Ashman Endosseous plastic implant method
US6524274B1 (en) 1990-12-28 2003-02-25 Scimed Life Systems, Inc. Triggered release hydrogel drug delivery system
US20020055710A1 (en) * 1998-04-30 2002-05-09 Ronald J. Tuch Medical device for delivering a therapeutic agent and method of preparation
US20030086975A1 (en) * 2001-11-08 2003-05-08 Timothy Ringeisen Method for making a porous Polymeric material
US5707385A (en) 1994-11-16 1998-01-13 Advanced Cardiovascular Systems, Inc. Drug loaded elastic membrane and method for delivery
US6280411B1 (en) 1998-05-18 2001-08-28 Scimed Life Systems, Inc. Localized delivery of drug agents
US6419692B1 (en) 1999-02-03 2002-07-16 Scimed Life Systems, Inc. Surface protection method for stents and balloon catheters for drug delivery
US6544221B1 (en) 2000-08-30 2003-04-08 Advanced Cardiovascular Systems, Inc. Balloon designs for drug delivery
US6752826B2 (en) * 2001-12-14 2004-06-22 Thoratec Corporation Layered stent-graft and methods of making the same
US7077654B2 (en) * 2002-10-10 2006-07-18 JoAnn L. Burtness Visual math teaching method
US7048714B2 (en) * 2002-10-30 2006-05-23 Biorest Ltd. Drug eluting medical device with an expandable portion for drug release
US20050273049A1 (en) 2004-06-08 2005-12-08 Peter Krulevitch Drug delivery device using microprojections
US20060025848A1 (en) * 2004-07-29 2006-02-02 Jan Weber Medical device having a coating layer with structural elements therein and method of making the same
US8034066B2 (en) 2005-09-15 2011-10-11 Boston Scientific Scimed, Inc. Multi-layer medical balloons
US8888684B2 (en) 2006-03-27 2014-11-18 Boston Scientific Scimed, Inc. Medical devices with local drug delivery capabilities
US20080140002A1 (en) * 2006-12-06 2008-06-12 Kamal Ramzipoor System for delivery of biologically active substances with actuating three dimensional surface
US7909864B2 (en) * 2007-07-06 2011-03-22 Boston Scientific Scimed, Inc. Implantable medical devices having adjustable pore volume and methods for making the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020042645A1 (en) * 1996-07-03 2002-04-11 Shannon Donald T. Drug eluting radially expandable tubular stented grafts
US7011654B2 (en) * 1998-04-27 2006-03-14 Artemis Medical, Inc. Dilating and support apparatus with disease inhibitors and methods for use
US6989071B2 (en) * 2001-01-30 2006-01-24 Boston Scientific Scimed, Inc. Stent with channel(s) for containing and delivering biologically active material and method for manufacturing the same
US20050181004A1 (en) * 2003-11-10 2005-08-18 Angiotech International Ag Intravascular devices and fibrosis-inducing agents

Also Published As

Publication number Publication date
EP2234664B1 (en) 2014-02-12
US8070720B2 (en) 2011-12-06
EP2234664A4 (en) 2011-03-30
JP5430580B2 (ja) 2014-03-05
EP2234664A2 (en) 2010-10-06
CN101909687A (zh) 2010-12-08
WO2009088744A2 (en) 2009-07-16
WO2009088744A3 (en) 2009-10-22
JP2011509146A (ja) 2011-03-24
US20090182273A1 (en) 2009-07-16

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Granted publication date: 20140514