CN101909444B - 硬皮病治疗方法 - Google Patents

硬皮病治疗方法 Download PDF

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Publication number
CN101909444B
CN101909444B CN2008801242621A CN200880124262A CN101909444B CN 101909444 B CN101909444 B CN 101909444B CN 2008801242621 A CN2008801242621 A CN 2008801242621A CN 200880124262 A CN200880124262 A CN 200880124262A CN 101909444 B CN101909444 B CN 101909444B
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China
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ifn
type
antibody
treatment
patient
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CN2008801242621A
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Chinese (zh)
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CN101909444A (zh
Inventor
A·科伊尔
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AstraZeneca AB
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MedImmune Vaccines Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2008801242621A 2007-11-05 2008-11-05 硬皮病治疗方法 Active CN101909444B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US99617507P 2007-11-05 2007-11-05
US60/996,175 2007-11-05
US10045408P 2008-09-26 2008-09-26
US61/100,454 2008-09-26
PCT/US2008/082481 WO2009061818A1 (en) 2007-11-05 2008-11-05 Methods of treating scleroderma

Publications (2)

Publication Number Publication Date
CN101909444A CN101909444A (zh) 2010-12-08
CN101909444B true CN101909444B (zh) 2013-09-18

Family

ID=43087976

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801242621A Active CN101909444B (zh) 2007-11-05 2008-11-05 硬皮病治疗方法

Country Status (21)

Country Link
US (1) US20110008365A1 (https=)
EP (1) EP2219452B1 (https=)
JP (2) JP5767475B2 (https=)
KR (1) KR20100098620A (https=)
CN (1) CN101909444B (https=)
AU (1) AU2008324800B2 (https=)
BR (1) BRPI0819195A2 (https=)
CA (1) CA2703705A1 (https=)
CY (1) CY1117251T1 (https=)
DK (1) DK2219452T3 (https=)
ES (1) ES2557352T3 (https=)
HR (1) HRP20151403T1 (https=)
HU (1) HUE025787T2 (https=)
IL (1) IL205452A (https=)
MX (1) MX2010004814A (https=)
NZ (1) NZ585064A (https=)
PL (1) PL2219452T3 (https=)
PT (1) PT2219452E (https=)
RU (1) RU2530561C2 (https=)
SI (1) SI2219452T1 (https=)
WO (1) WO2009061818A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20160855T1 (hr) 2008-02-08 2016-09-23 Medimmune, Llc Anti-ifnar1 protutijela sa smanjenim afinitetom fc liganda
CN103732251A (zh) * 2011-05-25 2014-04-16 米迪缪尼有限公司 用针对干扰素-α的抗体治疗全身性红斑狼疮、硬皮病以及肌炎的方法
AU2013274389A1 (en) * 2012-06-13 2015-01-22 Astrazeneca Ab Fixed dosage regimens for anti-type I interferon receptor (IFNAR) antibodies
US20180335431A1 (en) * 2015-11-17 2018-11-22 The Regents Of The University Of Colorado A Body Corporate Novel multiplex assays to diagnose or evaluate diseases or disorders in mammals
HRP20231255T1 (hr) 2021-04-23 2024-02-02 Astrazeneca Ab Režim doziranja anti-ifnar1 za potkožnu injekciju
CN118320101B (zh) * 2024-06-14 2024-09-17 天津嘉氏堂科技有限公司 iNOS抑制剂在制备治疗硬皮病胶原沉积药物中的应用

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US20070092890A1 (en) * 2005-08-05 2007-04-26 Genentech, Inc. Methods and compositions for detecting autoimmune disorders

Also Published As

Publication number Publication date
EP2219452A4 (en) 2012-05-02
NZ585064A (en) 2012-08-31
ES2557352T3 (es) 2016-01-25
JP5767475B2 (ja) 2015-08-19
HRP20151403T1 (hr) 2016-02-12
HUE025787T2 (en) 2016-05-30
EP2219452B1 (en) 2015-10-14
DK2219452T3 (en) 2016-01-11
MX2010004814A (es) 2010-08-10
JP2014144966A (ja) 2014-08-14
PT2219452E (pt) 2016-01-26
BRPI0819195A2 (pt) 2017-05-23
IL205452A0 (en) 2010-12-30
KR20100098620A (ko) 2010-09-08
US20110008365A1 (en) 2011-01-13
CA2703705A1 (en) 2009-05-14
PL2219452T3 (pl) 2016-04-29
CY1117251T1 (el) 2017-04-26
AU2008324800B2 (en) 2014-03-27
JP2011503008A (ja) 2011-01-27
IL205452A (en) 2016-02-29
AU2008324800A1 (en) 2009-05-14
EP2219452A1 (en) 2010-08-25
HK1151190A1 (zh) 2012-04-05
WO2009061818A1 (en) 2009-05-14
CN101909444A (zh) 2010-12-08
RU2010122644A (ru) 2011-12-20
SI2219452T1 (sl) 2016-03-31
RU2530561C2 (ru) 2014-10-10

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