CN101897758A - Traditional Chinese medicinal composition for curing animal womb inflammation and other postpartum diseases - Google Patents
Traditional Chinese medicinal composition for curing animal womb inflammation and other postpartum diseases Download PDFInfo
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- CN101897758A CN101897758A CN201010230302XA CN201010230302A CN101897758A CN 101897758 A CN101897758 A CN 101897758A CN 201010230302X A CN201010230302X A CN 201010230302XA CN 201010230302 A CN201010230302 A CN 201010230302A CN 101897758 A CN101897758 A CN 101897758A
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Abstract
The invention discloses a traditional Chinese medicinal composition for curing vagina diseases such as animal womb inflammation, postpartum diseases and the like. The traditional Chinese medicinal composition comprises the following active ingredients by weight: 140 +/- 10.0g of folium eucalypti extract, 140 +/- 10.0g of lavender extract, 200 +/- 10.0g of thymol and 4 +/- 1g of borneol. The traditional Chinese medicinal composition may also comprise 550 to 600g of excipient. The traditional Chinese medicinal composition can be applied locally to act on an affected part directly and forms a high medicinal concentration locally for quick response; and the medicament effect lasts for a long time and flushing in wombs is avoided, so inflammation spreading caused by inflammation further inward spreading in the process of flushing is prevented and good curative effect is produced. The medicine is nonirritant, causes fewer allergic reactions and avoids medicinal residue in bodies of animals. The traditional Chinese medicinal composition can prevent and cure vagina diseases such as acute and chronic endometritis, vaginitis, trichomonad or candida vaginitis, retention of afterbirth, dystocia and the like of livestock animals, can eliminate lochia and ensures normal progenitive functions of delivering females.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for animals, particularly combine the medicine of vagina illness such as inflammation of uterus, vaginitis, infusorian or the candidal vaginitis that can treat livestock animals, retained afterbirth, difficult labour with natural medicinal plants and natural organic matter.
Background technology
The endometritis of pig and other domestic animals is the inflammation of uterine mucosa.Endometritis is that pathogenic microorganism is invaded the uterus, a kind of commonly encountered diseases that has broken through genitals's defensive enginery and caused, performance hyperemia, congestion, edema, tissue permeability increase, mucosa injury comes off down to a series of pathological processes of suppurating, simultaneously normal physiological function forfeiture.The endometritis of pig and other domestic animals is the important diseases that influences animal husbandry development and economic benefit lifting.Sickness rate reaches 5-30% in China, though the sow non-estrus that causes because of endometritis or oestrus and join infertile about 70% of the sow reproductive system disease that accounts for repeatly.Sow easily causes rate of fertilization to reduce after suffering from endometritis, the increase of nonproductive natural law, and the birth piglet is weak and sickly, and the sow mortality increases, and causes serious economic loss.Treat the genital disease of domestic animals such as pig at present, carry out antiinflammatory in the body, adopt that vagina and cervix uteri are placed vagestrol, prednisone powder affected part directly sterilizes with intramuscular injection penicillin, streptomycin, or with potassium permanganate caustic washing vagina and the drain of extending oil sliver.And endometritis is the mucosa shape, can not bear that mealy medicine stimulates or corrosion, above-mentioned external used medicine can not be treated endometritis simultaneously, and the pathogenic bacteria of endometritis can spread transfer and immerses vagina, pudendum and pelvic cavity again, influence therapeutic effect, the extended treatment time.
Summary of the invention
Purpose of the present invention just provides a kind of novel combine with natural medicinal plants and natural organic matter, the medicine of treatment pig and other endometritis of livestock, this medicine has inhibitory or killing effect and good antiinflammatory action to the pathogenic microorganism that causes inflammation, also have the effect that promotes that the rheuminess thing is discharged, and do not have a Drug resistance.
The active component of drug regimen of the present invention comprises Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol, Borneolum Syntheticum.
The weight proportion of pharmaceutical composition of the present invention is: Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 140g ± 10.0g, Herba Lysimachiae foenum-graeci extract 140g ± 10.0g, thymol 200g ± 10.0g, Borneolum Syntheticum 4g ± 1g.
Allocate excipient 550～600g in the pharmaceutical composition of the present invention into.
The present invention is when the preparation infusion liquid, but the excipient vegetable oil specifically can be Oleum Helianthi or soybean oil or Petiolus Trachycarpi oil or Oleum Camelliae.
Pharmaceutical composition of the present invention is when preparation suppository, but the excipient natural oil specifically can be cocoa butter, oleum sapii or Oleum Linderae.
Infusion liquid preparation method of the present invention is: vegetable oil was sterilized 15-30 minute at 120-160 ℃, when treating that oil temperature drops to 40-60 ℃, add Borneolum Syntheticum, stirring makes fully melts, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol are added respectively in the above oil solution, fully stir, cross colloid mill 3～4 times promptly, fill after a while gets final product.
The preparation method of suppository of the present invention is: natural oil is heated to 30～40 ℃, after melting fully, add Borneolum Syntheticum and make fully and melt, add Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol respectively and fully stir, pour into and make its cooling forming in the suppository mould, packing gets final product after a while.
Pharmaceutical composition of the present invention can further be made capsule, soft capsule, perfusion liquor.
The present composition adopts the mode of local application, directly act on the affected part, form higher drug level in the part, rapid-action, longer duration, and do not need to carry out the intrauterine flushing, avoided further inwardly spreading because of flushing process makes inflammation, and the infection that causes diffusion, so good therapeutic effect can be arranged.Set of dispense that the present invention adopts than and the condition of drug level under, the medicine nonirritant, anaphylaxis is few.And medicine is the pure natural component, can not cause the intravital drug residue of animal, can prevent and treat the vagina illness such as acute and chronic endometritis, vaginitis, infusorian or candidal vaginitis, retained afterbirth, difficult labour of livestock animals, and can eliminate lochia, the reproductive capability of the female animal of guaranteeing to give a birth is normal.
The specific embodiment
Pharmaceutical composition of the present invention is to be combined by Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol, Borneolum Syntheticum, vegetable oil.That thymol has is anticorrosion, sterilization and anthelmintic action, and it all has inhibitory action to staphylococcus aureus, escherichia coli, interaction property and phenols seemingly, and effect stronger (phenol coefficient is 25).Thymol has the paralysis effect to ancylostome, whipworm.The Folium eucalypti globueli (Eucalyptus globulus Labill.) extract all has inhibitory action external to staphylococcus aureus, Hemolytic streptococcus, bloody dysentery bacillus, Bacillus typhi, escherichia coli, bacillus pyocyaneus etc.Has the trichomonas vaginitis of killing effect in addition.Herba Lysimachiae foenum-graeci extract is that a kind of antibacterial is used to be coated with and puts wound on the skin, plays sterilization and promotes skin healing, reduces the cicatrix effect.It can suppress 17 kinds of antibacterials (G+ and G-) and 10 kinds of fungi growth.Experiment in vitro shows, concentration is lower than the effect that 1% Herba Lysimachiae foenum-graeci extract has methicillin-resistant drug-resistant staphylococcus aureus (MRSA) and enterococcus faecalis.Borneolum Syntheticum has anti-inflammation and analgesic effect.Can effectively suppress or kill clinical common bacterias such as staphylococcus aureus, beta hemolytic streptococcus, viridans streptococci.Sunflower oil contains abundant vitamin E, and the recovery from illness that local use can be quickened to damage is clinically controlled dysentery, saturating carbuncle with it, and the report with its treatment endometritis is arranged separately.All medicines are collaborative in the side, brings into play antibacterial, antiinflammatory, detumescence, removing the necrotic tissue and promoting granulation, improve the effect of uterus blood circulation, promotion uterus functional recovery.The present invention is an oil preparation, and oil preparation can well disperse liposoluble constituent, has good flowability and penetration simultaneously, helps medicine and scatters and play a role.Therefore the present invention is a kind of durative action preparation, and more general water preparation can reduce administration number of times, has made things convenient for clinical practice.
Find that through relevant test medicine of the present invention has anti-inflammation, promote the discharge of intrauterine rheuminess thing, guarantee the purification in the cavity of uterus, accelerate the function that local inflammation dissipates and physiological function recovers.
The present invention is described in detail below in conjunction with embodiment.
Embodiment 1: the preparation of perfusion liquor:
Get Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 135g, Herba Lysimachiae foenum-graeci extract 130g, thymol 210g, Borneolum Syntheticum 5g, Oleum Helianthi 520g, oil 150 ℃ of sterilizations 15-30 minute, when treating that oil temperature drops to 50 ℃, is added Borneolum Syntheticum, stirring makes fully melts, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol are added respectively in the above oil solution, fully stir, cross colloid mill 3～4 times promptly.Fill after a while becomes the 100ml/ bottle.
Embodiment 2: the preparation of perfusion liquor:
Get Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 140g, Herba Lysimachiae foenum-graeci extract 130g, thymol 210g, Borneolum Syntheticum 5g, soybean oil 520g
Oil 150 ℃ of sterilizations 30 minutes, when treating that oil temperature drops to 50 ℃, is added Borneolum Syntheticum, stir to make fully and melt, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol are added respectively in the above oil solution, fully stir, cross colloid mill 3～4 times promptly.Fill after a while becomes the 100ml/ bottle.
Embodiment 3: the preparation of perfusion liquor:
Get Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 135g, Herba Lysimachiae foenum-graeci extract 140g, thymol 200g, Borneolum Syntheticum 4g, Petiolus Trachycarpi oil 510g sterilizes oil 30 minutes at 150 ℃, when treating that oil temperature drops to 55 ℃, add Borneolum Syntheticum, stirring makes fully melts, and Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol are added respectively in the above oil solution, fully stirs, cross colloid mill 3～4 times promptly, fill after a while becomes the 100ml/ bottle.
Embodiment 4: the preparation of perfusion liquor:
Get Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 150g, Herba Lysimachiae foenum-graeci extract 150g, thymol 210g, Borneolum Syntheticum 3g, sunflower seed 600g sterilizes oil 20 minutes at 120-150 ℃, when treating that oil temperature drops to 60 ℃, add Borneolum Syntheticum, stirring makes fully melts, and Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol are added respectively in the above oil solution, fully stirs, cross colloid mill 3～4 times promptly, fill after a while becomes the 100ml/ bottle.
Embodiment 5: the preparation of perfusion liquor:
Get Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 130g, Herba Lysimachiae foenum-graeci extract 130g, thymol 210g, Borneolum Syntheticum 5g, Oleum Camelliae 580g sterilizes oil 30 minutes at 150 ℃, when treating that oil temperature drops to 40 ℃, add Borneolum Syntheticum, stirring makes fully melts, and Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol are added respectively in the above oil solution, fully stirs, cross colloid mill 3～4 times promptly, fill after a while becomes the 100ml/ bottle.
Embodiment 6: the preparation of suppository
Get Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 135g, Herba Lysimachiae foenum-graeci extract 136g, thymol 190g, Borneolum Syntheticum 4g, cocoa butter 520g.
Cocoa butter is heated to 35 ℃, after melting fully, adds Borneolum Syntheticum and make fully and melt, add Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol respectively and fully stir, pour into and make its cooling forming in the suppository mould.Packing gets final product after a while.
Embodiment 7: the preparation of suppository
Get Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 150g, Herba Lysimachiae foenum-graeci extract 150g, thymol 205g, Borneolum Syntheticum 4g, oleum sapii 500g.
Oleum sapii is heated to 30～40 ℃, after melting fully, adds Borneolum Syntheticum and make fully and melt, add Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol respectively and fully stir, pour into and make its cooling forming in the suppository mould.Packing gets final product after a while.
Embodiment 8: the preparation of suppository
Get Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 130g, Herba Lysimachiae foenum-graeci extract 140g, thymol 210g, Borneolum Syntheticum 4g, Oleum Linderae 600g.
Oleum sapii is heated to 35 ℃, after melting fully, adds Borneolum Syntheticum and make fully and melt, add Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol respectively and fully stir, pour into and make its cooling forming in the suppository mould.Packing gets final product after a while.
Embodiment 9: the preparation of soft capsule
Get Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 135g, Herba Lysimachiae foenum-graeci extract 135g, thymol 205g, Borneolum Syntheticum 5g, Oleum Helianthi 520g
Oil 150 ℃ of sterilizations 30 minutes, when treating that oil temperature drops to 50 ℃, is added Borneolum Syntheticum, stir to make fully and melt, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol are added respectively in the above oil solution, fully stir, cross colloid mill 3～4 times.
Gelatin is put into the distilled water immersion make its expansion, treat that gelatin dissolves the back unclassified stores is added in the lump, mix; The glue for preparing is coated on the smooth plate surface, makes thickness even, with about 90 ℃ temperature heating, make the surface moisture evaporation then, the cushion compound that evaporation is good pelleting mold pressing system.
Embodiment 10: the preparation of soft capsule
Get Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 135g, Herba Lysimachiae foenum-graeci extract 135g, thymol 205g, Borneolum Syntheticum 5g, soybean oil 580g
Oil 120-160 ℃ ℃ of sterilization 15-30 minute, when treating that oil temperature drops to 40-60 ℃, is added Borneolum Syntheticum, stir to make fully and melt, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol are added respectively in the above oil solution, fully stir, cross colloid mill 3～4 times.
Gelatin is put into the distilled water immersion make its expansion, treat that gelatin dissolves the back unclassified stores is added in the lump, mix; The glue for preparing is coated on the smooth plate surface, makes thickness even, with about 90 ℃ temperature heating, make the surface moisture evaporation then, the cushion compound that evaporation is good pelleting mold pressing system.
Above made medicine is carried out following test:
Stability test
The medicine placement is tested after 2 years by drug storage, and its result shows that the physics and chemistry of medicine of the present invention and biological stability all keep well meeting " Chinese veterinary drug allusion quotation " (2005 editions two ones') relevant requirements.Therefore the present invention has good stable.
Safety examination
Animal subject is 4 adult white rabbit, body weight 2.5～3kg (available from Bo Meilai biological product company limited Experimental Animal Center), and the clinical health inspection is all normal before the test.With aforementioned gained medicine for being subjected to the reagent thing.
Test method
Splash into to every day the experimental rabbits left eye and be subjected to reagent thing medicine of the present invention, right eye splashes into the preparation vegetable oil, each 0.1ml, forced the rabbit eyes closed 10 seconds with hands, continuously eye drip is 7 days, behind eye drip first 6 hours with eye drip at every turn before the local response situation of observed and recorded eye, continue after the drug withdrawal to observe 7 days, mark respectively by related standards corneal, iris and conjunctiva, calculate meansigma methods, and compare with the contrast eye of same rabbit.
Result of the test
Result of the test shows that with behind the eye drip of the present invention, the eye conjunctiva has hyperemia slightly, and the comprehensive average mark of eye irritation slightly raises than the eye that drips vegetable oil with a rabbit offside, but still in non-irritating numerical range.The result shows that the present invention does not have zest to mucosa, is safe.
Pharmacological experiment
Material and method
Material
1. extracorporeal bacteria inhibitor test
A.1 the medicine with the preceding method preparation is a trial drug, and the contrast medicine is ciprofloxacin injection (commercially available)
A.2 test strain is selected clinical middle 5 kinds of main pathogenic bacterium that confirm, escherichia coli, staphylococcus, streptococcus pyogenes, bacteroid and clostridium for use.Every kind of each 3 strain of antibacterial, above strain is from the pathological material of disease of the clinical type endometritis of trouble of pig farms, ground such as Jiangxi, Hubei collection, through the strain of isolation identification preservation.
Method:
The bacterial strain that cylinder plate method carries out 5 kinds of main pathogenic bacterium that bacteriostatic test will preserve is inoculated into respectively and places 37 ℃ of incubators to cultivate in the common steamed beef soup pipe 24 hours, after smear for microscopic examination is pure, different strain is carried out the dilution (do trial test earlier and measure optimum diluting multiple) of different multiples.Bottom is evenly paved agar in the plate, bacterium liquid evenly is distributed on the bottom-layer agar at the stand with crooked L type Glass rod after adding agar, last placing steel tubes, (lot number is respectively H080301, H080302 with uterus perfusion of the present invention, H080303), experimental concentration is an original content, contrast medicine ciprofloxacin injection, and experimental concentration is 2% to inject steel pipe respectively, 37 ℃ of incubators were cultivated 24 hours, took out the bacteriostatic diameter with each sample of vernier caliper measurement
The criterion antibacterial circle diameter is a drug resistance less than 10mm, and 10-15mm is a medium sensitivity, and＞15mm is extremely sensitive
The result
Test shows that medicine of the present invention has certain fungistatic effect to 5 kinds of pathogenic bacterium (15 strain), and is extremely sensitive to clostridium, to escherichia coli, streptococcus pyogenes, bacteroid medium sensitivity, general to the staphylococcus fungistatic effect.All in all, medicine bacteriostasis of the present invention obviously is better than ciprofloxacin
2. clinical trial and clinical verification
A material and method
A.1 treating case selects
Puerperal is long-term discharges mucus or lochia, or vaginal orifice flows out yellow-white or the opaque mucus of lark is joined infertile sow repeatly when oestrusing
A.2 drug usage and consumption
The uterus perfusion, once a day, each 20～30ml, 3 times was 1 course of treatment.
A.3 criterion of therapeutical effect
Effectively: no mucus or lochia discharge vaginal orifice root of the tail are clean, and deferent duct inserts cervix uteri and takes out, and tube wall does not have mucus or the purulence thing adheres to, and the breeding of the second feelings phase is become pregnant.
Take a turn for the better: no mucus or lochia are discharged, and the vaginal orifice root of the tail is clean, and deferent duct inserts cervix uteri and takes out, and tube wall has a small amount of mucus to adhere to, and vaginal orifice has a small amount of HUANGBAI(sic) or lark mucus to discharge when oestrusing, and it is infertile to breed.
Invalid: vagina still has mucus or lochia to discharge after the medication, and the vaginal orifice root of the tail has mucus to adhere to, and can't breed.
Result of the test
Medicine of the present invention is treated altogether and is suffered from pig 123 examples, cures produce effects 89 examples 1 course of treatment, and cure rate is cured 112 examples 72.35%, 2 course of treatment, cure rate 91.06%, 3 examples that take a turn for the better, total effective rate 93.50%.
Claims (10)
1. Chinese medicine composition for the treatment of vagina illness such as animal womb inflammation and puerperal disease, it is characterized in that: active component comprises Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol, Borneolum Syntheticum.
2. Chinese medicine composition according to claim 1 is characterized in that: Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 140g ± 10.0g, Herba Lysimachiae foenum-graeci extract 140g ± 10.0g, thymol 200g ± 10.0g, Borneolum Syntheticum 4g ± 1g.
3. Chinese medicine composition according to claim 2 is characterized in that: allocate excipient 500～600g. into
4. Chinese medicine composition according to claim 3 is characterized in that: when the preparation infusion liquid, excipient is a vegetable oil.
5. Chinese medicine composition according to claim 3 is characterized in that: when preparation suppository, excipient is a natural oil.
6. according to claim 1 or 2 or 3 or 4 described Chinese medicine compositions, it is characterized in that: can further make capsule, soft capsule, perfusion liquor.
7. Chinese medicine composition according to claim 4 is characterized in that: vegetable oil is Oleum Helianthi or soybean oil or Petiolus Trachycarpi oil or Oleum Camelliae.
8. Chinese medicine composition according to claim 5 is characterized in that: natural oil is cocoa butter or oleum sapii or Oleum Linderae.
9. Chinese medicine composition according to claim 4, it is characterized in that: its preparation method was: with vegetable oil 120-160 ℃ of sterilization 15-30 minute, when treating that oil temperature drops to 40-60 ℃, add Borneolum Syntheticum, stirring makes fully melts, and Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol are added respectively in the above oil solution, fully stirs, cross colloid mill 3～4 times promptly, fill after a while gets final product.
10. Chinese medicine composition according to claim 5, it is characterized in that: its preparation method is: natural oil is heated to 30～40 ℃, after melting fully, add Borneolum Syntheticum and make thawing fully, adding Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Herba Lysimachiae foenum-graeci extract, thymol respectively fully stirs, pour into and make its cooling forming in the suppository mould, packing gets final product after a while.
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| CN103239681A (en) * | 2013-05-22 | 2013-08-14 | 江西博莱大药厂 | Compound tasmanian bluegum leaf Chinese herbal composition and preparation method thereof |
| CN105193934A (en) * | 2015-10-21 | 2015-12-30 | 中国农业科学院兰州畜牧与兽药研究所 | Compound essential oil for treating endometritis of domestic animals and preparation method thereof |
| CN106106364A (en) * | 2016-07-29 | 2016-11-16 | 董标 | A kind of cultural method improving sow reproductive performance |
| CN107260827A (en) * | 2017-05-10 | 2017-10-20 | 中国农业科学院兰州畜牧与兽药研究所 | It is a kind of to be used to treat compound essential oil of milk cow retention of afterbirth and preparation method thereof |
| US20210033584A1 (en) * | 2019-07-31 | 2021-02-04 | Dräger Safety AG & Co. KGaA | Mobile measuring device, system and process for a safety-relevant application |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103239681A (en) * | 2013-05-22 | 2013-08-14 | 江西博莱大药厂 | Compound tasmanian bluegum leaf Chinese herbal composition and preparation method thereof |
| CN105193934A (en) * | 2015-10-21 | 2015-12-30 | 中国农业科学院兰州畜牧与兽药研究所 | Compound essential oil for treating endometritis of domestic animals and preparation method thereof |
| CN106106364A (en) * | 2016-07-29 | 2016-11-16 | 董标 | A kind of cultural method improving sow reproductive performance |
| CN106106364B (en) * | 2016-07-29 | 2019-03-08 | 深圳农畉农产品有限公司 | A kind of cultural method improving sow reproductive performance |
| CN107260827A (en) * | 2017-05-10 | 2017-10-20 | 中国农业科学院兰州畜牧与兽药研究所 | It is a kind of to be used to treat compound essential oil of milk cow retention of afterbirth and preparation method thereof |
| CN107260827B (en) * | 2017-05-10 | 2020-11-20 | 中国农业科学院兰州畜牧与兽药研究所 | Compound essential oil for treating retained afterbirth of dairy cow and preparation method thereof |
| US20210033584A1 (en) * | 2019-07-31 | 2021-02-04 | Dräger Safety AG & Co. KGaA | Mobile measuring device, system and process for a safety-relevant application |
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