CN101897623B - Simulation smoke exposure experimental box - Google Patents

Simulation smoke exposure experimental box Download PDF

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Publication number
CN101897623B
CN101897623B CN2010102442624A CN201010244262A CN101897623B CN 101897623 B CN101897623 B CN 101897623B CN 2010102442624 A CN2010102442624 A CN 2010102442624A CN 201010244262 A CN201010244262 A CN 201010244262A CN 101897623 B CN101897623 B CN 101897623B
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China
Prior art keywords
casing
annular groove
experimental box
seal cover
box according
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Expired - Fee Related
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CN2010102442624A
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Chinese (zh)
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CN101897623A (en
Inventor
孙磊
安辉
郑有科
周燕虹
曹佳
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Third Military Medical University TMMU
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Third Military Medical University TMMU
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Abstract

The invention discloses a simulation smoke exposure experimental box which comprises a box body and a sealing cover, wherein a smoke inlet is arranged at the bottom part of the box body, a smoke outlet is arranged on the side wall of the top part, an annular groove is arranged at the top part, and liquid is contained in the annular groove; and the sealing cover is covered on the annular groove, an annular vertical wall is arranged thereon, the annular vertical wall is embedded in the annular groove, and the bottom part of the annular vertical wall is immersed in the liquid, thereby not only sealing the box body, but also forming a gas channel between the sealing cover and the annular groove for leading gas in the box body to escape when the pressure in the box body is larger, and further keeping the pressure in the box body constant. Therefore, the simulation smoke exposure experimental box provided by the embodiment of the application can control the gas pressure in the exposure experimental box when carrying out an exposure experiment, avoid an experimental animal in the box from producing barotraumas, lead the smoke inhalation to become the sole wound-causing factor, avoid the bias of the barotraumas and improve the accuracy and the scientificity of exposure experimental data.

Description

Simulation smoke exposure experimental box
Technical field
The application relates to biomedical contamination apparatus field, particularly relates to a kind of simulation smoke exposure experimental box.
Background technology
In recent years, develop by leaps and bounds along with socioeconomic, great variety is also taking place in existent environment of people and life style.Meanwhile, the incidence rate of fire is also soaring constantly, and serious threat people's existence with healthy.
According to CTIF global fire investigation statistics is shown, 600~7,000,000 fire of the annual generation in the whole world in recent years, nearly 6~70,000 people die in fire; China's dead number in fire in every year is 2100 people, occupies the 4th in the whole world.And big quantity research shows, 85% victim is suction but not a direct burn of dying from toxic smog in the fire.Research for the fire burn is paid attention to by people very early, has also obtained the achievement in research of attracting attention; And smoke inhalation injury research is started late, and relevant damage treatment research does not yet have significant progress.Trace it to its cause, changeable except the smog condition, the smog composition is various, the machine-processed complicacy of damage, the condition control that smog takes place with contamination device also is a primary technical bottleneck.
Through to prior art research; The applicant finds: existing exposure experimental box is in the simulation smoke exposure experiment; Smog produces the back and is transported to through power-equipment and carries out exposure experiment in the smoke exposure experimental box and since power set can be constantly with smoke delivery in smoke exposure experimental box, cause the pressure in its smoke exposure experimental box to increase; Laboratory animal possibly produce windage, thereby disturbs the accuracy of smoke exposure experimental data.Therefore existing smoke exposure experimental box can not better satisfy the relevant scientific research demand of contamination.
Summary of the invention
In view of this, the application embodiment provides a kind of simulation smoke exposure experimental box, to realize the accomplishing experiment that smog takes place and contamination is relevant better.
For realizing above-mentioned purpose, technical scheme is following:
A kind of simulation smoke exposure experimental box comprises: casing and seal cover,
Wherein: the bottom of said casing is provided with the smog import, and the top sidewall is provided with smog outlet, and the top is provided with annular groove, and is contained with liquid in the said annular groove;
Said seal cover covers on the said annular groove, and it is provided with annular wall, and said annular wall is embedded in the said annular groove and the bottom is immersed in the said liquid, with box sealing;
When gas pressure in the said casing surpasses preset value, between said seal cover and said annular groove, form gas passage, make gas evolution in the said casing, keep the intravital constant pressure of said case;
When the intravital gas pressure of said case is reduced to preset value when following, the liquid between said seal cover and the said annular groove is once more with said box sealing.
Preferably, said annular wall is embedded in the said annular groove movably.
Preferably, said seal cover or the annular wall on it and said annular groove removably connect, and are provided with the gap between said seal cover and said annular wall and the said annular groove.
Preferably, this experimental box further comprises: the mixing fan, be arranged on the bottom or the said casing top of said seal cover, and be used for the intravital smog of the said case of mix homogeneously.
Preferably, this experimental box further comprises: at least one porous barrier, be arranged on said box house, and said casing is separated into a plurality of relatively independent spaces.
Preferably, said porous barrier is 6, during said 6 porous barriers are separated into said casing following three layers, and respectively there are 3 separate space in middle level and lower floor.
Preferably, said cabinet wall is provided with protruding rib and holddown groove, is used for fixing said porous barrier.
Preferably, the liquid in the said annular groove is water or sodium bicarbonate solution, is used to absorb the smog that said casing disengages.
Preferably, the material of said casing is a transparent material.
Preferably, said casing is a square column type or cylindrical.
Technical scheme by above the application embodiment provides is visible, and this simulation smoke exposure experimental box, seal cover cover the casing top, and the annular wall on the seal cover is embedded in the annular groove that is contained with water.When gas pressure in the said casing surpasses preset value, between said seal cover and said annular groove, form gas passage, make gas evolution in the said casing, keep the intravital constant pressure of said case; When the intravital gas pressure of said case is reduced to preset value when following, full of liquid again between said seal cover and the said annular groove is with said box sealing.
Therefore this simulation smoke exposure experimental box can be controlled the pressure of gas in the exposure experimental box when carrying out exposure experiment, makes the laboratory animal in the case avoid producing windage, improves the accuracy and the science of exposure experiment data.
The simulation smoke exposure experimental box that provides of the application embodiment simultaneously; Can also be through the weight that changes seal cover or the degree of depth that changes the annular wall immersion water surface; Preset value that can free adjustment casing internal pressure, the intravital pressure of guard box is in suitable scope.
In addition, the simulation smoke exposure experimental box that the application embodiment provides, casing wall adopt transparent material to process, the state of the laboratory animal when exposure experiment in the convenient inspection box at any time.Use porous barrier that box house is separated into independently a plurality of and vertical toxicant exposure chamber, when exposure experiment, can effectively avoid laboratory animal to flock together or fight, guarantee that laboratory animal evenly contaminates.And the casing top also is provided with the mixing fan, when exposure experiment, can also and be full of whole exposure experimental box with the intravital smog mix homogeneously of case.So the above-mentioned accuracy and science that can improve the exposure experiment data equally that be provided with of this simulation exposure experimental box.
Description of drawings
In order to be illustrated more clearly in the application embodiment or technical scheme of the prior art; To do to introduce simply to the accompanying drawing of required use in embodiment or the description of the Prior Art below; Obviously, the accompanying drawing in describing below only is some embodiment that put down in writing among the application, for those of ordinary skills; Under the prerequisite of not paying creative work, can also obtain other accompanying drawing according to these accompanying drawings.
The schematic appearance one of the simulation smoke exposure experimental box that Fig. 1 provides for the application embodiment one;
The schematic appearance two of the simulation smoke exposure experimental box that Fig. 2 provides for the application embodiment one;
The internal structure sketch map of the simulation smoke exposure experimental box that Fig. 3 provides for the application embodiment one;
The internal structure sketch map of the another kind of simulation smoke exposure experimental box that Fig. 4 provides for the application embodiment one;
The structural representation of the seal cover that Fig. 5 provides for the application embodiment one;
The schematic appearance of the simulation smoke exposure experimental box that Fig. 6 provides for the application embodiment two;
The cutaway view one of the simulation smoke exposure experimental box that Fig. 7 provides for the application embodiment three;
The cutaway view two of the simulation smoke exposure experimental box that Fig. 8 provides for the application embodiment three.
The specific embodiment
In order to make those skilled in the art person understand the technical scheme among the application better; To combine the accompanying drawing among the application embodiment below; Technical scheme among the application embodiment is carried out clear, intactly description; Obviously, described embodiment only is the application's part embodiment, rather than whole embodiment.Based on the embodiment among the application, those of ordinary skills are not making the every other embodiment that is obtained under the creative work prerequisite, all should belong to the scope of the application's protection.
Embodiment one:
Fig. 1 implements the schematic appearance one of the simulation smoke exposure experimental box that an example provides for the application.
Fig. 2 implements the schematic appearance two of the simulation smoke exposure experimental box that an example provides for the application.
As depicted in figs. 1 and 2, this simulation exposure experimental box comprises: casing 1 and seal cover 2, seal cover 2 covers the top of casing 1.
The side walls of casing 1 is provided with smog import 4, and the top sidewall is provided with smog outlet 3, when carrying out exposure experiment; Laboratory animal is placed on the inside of casing 1; Smog gets into casing 1 by smog import 4, goes out from smog outlet 3 again, accomplishes the smoke exposure experiment.The material of casing 1 is a transparent material, and in experiment, the experimenter just can arrive the contamination situation of casing 1 inner laboratory animal in the visual observation of casing 1 like this.In addition, the shape of casing 1 can be square column type or cylindrical, and in the application embodiment, the shape of casing 1 is preferably square column type.
Fig. 3 implements the internal structure sketch map of the simulation smoke exposure experimental box that an example provides for the application.
As shown in Figure 3, the edge, top of casing 1 is provided with annular groove 5, can receiving fluids in the annular groove 5.In the application embodiment, the liquid that holds in the annular groove 5 can be water, can also be sodium bicarbonate solution, smog that overflows when being used for the respiratory box inner high voltage and gas.In addition, present technique field those of ordinary skill should be understood that annular groove is arranged on the preferred embodiment that edge, casing top is the application; Should not constitute restriction to the application; In other embodiment of the application, annular groove can also be arranged on other positions at casing top, for example side angle part; As shown in Figure 4, implement the internal structure sketch map of the another kind of simulation smoke exposure experimental box that an example provides for the application.Annular groove also can be designed to other forms in addition, for example with casing and the extraneous linker that communicates.
The structural representation of the seal cover that Fig. 5 provides for the application embodiment.
As shown in Figure 4, sealing lid 2 is provided with the annular wall 21 that is complementary with annular groove 5, and seal cover 2 is buckled on the annular groove 5, and annular wall 21 is embedded in the annular groove 5 movably, and the bottom of annular wall 21 is dipped in below the water surface.
The simulation exposure experimental box that the application embodiment provides is when carrying out exposure experiment; Because seal cover 2 can freely move up and down; So when the pressure in the casing 1 exceeded preset value, seal cover 2 will move upward under the effect of pressure, when annular wall 21 bottoms break away from the water surface; Gas in the casing 1 will be overflowed, and air pressure is corresponding will to be reduced.When the intravital pressure of case was lower than preset value, seal cover 2 will fall under the effect of gravity, and this moment, annular wall 21 was dipped in again below the water surface, with casing 1 top seal.In the application embodiment,, can the gas pressure in the casing 1 be adjusted in the suitable scope through changing the weight of seal cover 2.
Embodiment two:
As shown in Figure 6; Identical with embodiment one, in the application embodiment, the top of casing 1 is provided with annular groove 5 equally; Seal cover 2 covers on the annular groove 5 equally; Annular wall 21 on it also is embedded in the annular groove 5, and the bottom is dipped in below the water surface in the annular groove 5, with the top seal of casing 1.But among the application embodiment, the annular wall 21 on the seal cover 2 is not to be embedded in movably in the annular groove 5, but removably is connected with annular groove 5 through bolt 6, and is provided with the gap between seal cover 2 and annular wall 21 and the annular groove 5.
When using this simulation exposure experimental box to carry out exposure experiment; When the pressure in the casing 1 exceeds preset value; Though seal cover 2 can not move; But the intravital gas of case can form a gas passage and effusion with blowing out in the water in the gap between seal cover 2 and annular wall 21 and the annular groove 5, can the intravital pressure of case be reduced equally.And when the intravital pressure of case was lower than preset value, water can be filled into again in the gap between seal cover 2 and annular wall 21 and the annular groove 5, with casing 1 top seal.In the application embodiment, be dipped in the degree of depth below the water surface through changing annular wall 21 bottoms, can the gas pressure in the casing 1 be adjusted in the suitable scope equally.
Embodiment three:
On the basis of embodiment one and embodiment two, the simulation exposure experimental box that the application provides also comprises: porous barrier 7 and mixing fan 11.
Porous barrier 7 is arranged on the inside of casing 1, and casing 1 is isolated into a plurality of separate space, when being used to test, places animal to be tested.As shown in Figure 7, in the application embodiment, porous barrier 7 is 6, and during casing 1 is separated into following three layers, respectively there are 3 separate space in middle level and lower floor.In the application embodiment, as shown in Figure 8, among the application embodiment, also be provided with protruding rib 9 and holddown groove 10 on the inwall of casing 1, protruding rib 9 is on the inwall that horizontal annular is distributed in casing 1, is used for fixing the porous barrier 7 of horizontal positioned; Holddown groove 10 vertically is distributed on the cabinet wall, is used for fixing the porous barrier 7 of vertical placement.Porous barrier 7 is separated into separate and vertical a plurality of toxicant exposure chambers with exposure experimental box, when carrying out exposure experiment, can effectively avoid laboratory animal to flock together or fights, and guarantees that laboratory animal evenly contaminates.In addition, present technique field those of ordinary skill should be understood that in the application embodiment; Porous barrier is preferably 6; And 6 porous barriers are separated into three layers with casing, and respectively there are 3 separate space in middle level and lower floor, and this all is the application's a preferred embodiment; When experiment, the number that porous barrier number and exposure experimental box are separated out can change according to actual needs.Therefore, should not constitute restriction here to the application.
As shown in Figure 7; Mixing fan 11 is arranged on the bottom of seal cover 2 or the top of casing 1; Be used for when experiment, the smog in the casing 1 being carried out mix homogeneously; And the smog that makes mix homogeneously is full of the inside of whole box body 1, each local smokescope unanimity in the assurance casing 1, the homogeneity of smoke exposure in the raising zoopery.
The simulation smoke exposure experimental box that the application embodiment provides, seal cover cover the casing top, and the annular wall on the seal cover is embedded in the annular groove that is contained with water.When gas pressure in the said casing surpasses preset value, between said seal cover and said annular groove, form gas passage, make gas evolution in the said casing, keep the intravital constant pressure of said case; When the intravital gas pressure of said case is reduced to preset value when following, full of liquid again between said seal cover and the said annular groove is with said box sealing.
Therefore this simulation smoke exposure experimental box is when carrying out exposure experiment; Can control the pressure of gas in the exposure experimental box; Avoid the laboratory animal in the case to receive the high pressure damage; Smog is sucked becomes unique causative factors of injury, thereby has avoided the interference of high pressure Confounding Factor to this experiment, improves the accuracy and the science of exposure experiment data.
The simulation smoke exposure experimental box that provides of the application embodiment simultaneously; Can also be through the weight that changes seal cover or the degree of depth that changes the annular wall immersion water surface; Preset value that can free adjustment casing internal pressure, the intravital pressure of guard box is in suitable scope.
In addition, the simulation smoke exposure experimental box that the application embodiment provides, casing wall adopt transparent material to process, the state of the laboratory animal when exposure experiment in the convenient inspection box at any time.Use porous barrier that box house is separated into independently a plurality of and vertical toxicant exposure chamber, when exposure experiment, can effectively avoid laboratory animal to flock together or fight, guarantee that laboratory animal evenly contaminates.And the casing top also is provided with the mixing fan, when exposure experiment, can also and be full of whole exposure experimental box with the intravital smog mix homogeneously of case.So the above-mentioned accuracy and science that can improve the exposure experiment data equally that be provided with of this simulation exposure experimental box.
The above only is the application's a preferred implementation, makes those skilled in the art can understand or realize the application.Multiple modification to these embodiment will be conspicuous to one skilled in the art, and defined General Principle can realize under the situation of spirit that does not break away from the application or scope in other embodiments among this paper.Therefore, the application will can not be restricted to these embodiment shown in this paper, but will meet and principle disclosed herein and features of novelty the wideest corresponding to scope.

Claims (10)

1. a simulation smoke exposure experimental box is characterized in that, comprising: casing and seal cover,
Wherein: the bottom of said casing is provided with the smog import, and the top sidewall is provided with smog outlet, and the top is provided with annular groove, and is contained with liquid in the said annular groove;
Said seal cover covers on the said annular groove, and said seal cover is provided with annular wall, and said annular wall is embedded in the said annular groove and the bottom is immersed in the said liquid, with box sealing;
When gas pressure in the said casing surpasses preset value, between said seal cover and said annular groove, form gas passage, make gas evolution in the said casing, keep the intravital constant pressure of said case;
When the intravital gas pressure of said case be reduced to preset value when following liquid between said seal cover and the said annular groove once more with said box sealing.
2. experimental box according to claim 1 is characterized in that, said annular wall is embedded in the said annular groove movably.
3. experimental box according to claim 1 is characterized in that, said seal cover or the annular wall on it and said annular groove removably connect, and is provided with the gap between said seal cover and said annular wall and the said annular groove.
4. experimental box according to claim 1 is characterized in that, further comprises: the mixing fan, be arranged on the bottom or the said casing top of said seal cover, and be used for the intravital smog of the said case of mix homogeneously.
5. experimental box according to claim 1 is characterized in that, further comprises: at least one porous barrier, be arranged on said box house, and said casing is separated into a plurality of relatively independent spaces.
6. experimental box according to claim 5 is characterized in that, said porous barrier is 6, during said 6 porous barriers are separated into said casing following three layers, and respectively there are 3 separate space in middle level and lower floor.
7. experimental box according to claim 5 is characterized in that, said cabinet wall is provided with protruding rib and holddown groove, is used for fixing said porous barrier.
8. experimental box according to claim 1 is characterized in that, the liquid in the said annular groove is water or sodium bicarbonate solution, is used to absorb the smog that said casing disengages.
9. experimental box according to claim 1 is characterized in that, the material of said casing is a transparent material.
10. experimental box according to claim 9 is characterized in that, said casing is a square column type or cylindrical.
CN2010102442624A 2010-08-04 2010-08-04 Simulation smoke exposure experimental box Expired - Fee Related CN101897623B (en)

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Publication number Priority date Publication date Assignee Title
CN102353505B (en) * 2011-06-08 2013-11-27 苏州东菱振动试验仪器有限公司 Vibration test equipment pressure compensation method and apparatus thereof
CN106781945B (en) * 2016-12-21 2023-05-23 西安培华学院 Animal gas experiment box for teaching

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CN101103938A (en) * 2007-08-15 2008-01-16 庞宝森 Passive smoking flue toxicity contaminated box
CN101514979A (en) * 2009-03-31 2009-08-26 西安近代化学研究所 Gunpowder-mixed fuel gas bio-toxicological experiment compartment

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CN1036267A (en) * 1988-03-29 1989-10-11 冶金工业部钢铁研究总院 Autocontrol continuous experimental system for simulating toxicant environment
CN101103938A (en) * 2007-08-15 2008-01-16 庞宝森 Passive smoking flue toxicity contaminated box
CN101514979A (en) * 2009-03-31 2009-08-26 西安近代化学研究所 Gunpowder-mixed fuel gas bio-toxicological experiment compartment

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