CN101878226B - 精氨酸取代的新型合成肽及其应用 - Google Patents
精氨酸取代的新型合成肽及其应用 Download PDFInfo
- Publication number
- CN101878226B CN101878226B CN200880114504.9A CN200880114504A CN101878226B CN 101878226 B CN101878226 B CN 101878226B CN 200880114504 A CN200880114504 A CN 200880114504A CN 101878226 B CN101878226 B CN 101878226B
- Authority
- CN
- China
- Prior art keywords
- arg
- lys
- gln
- ser
- ala
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07120713A EP2060586A1 (en) | 2007-11-14 | 2007-11-14 | New synthetic arginine substituted peptides and their use |
| EP07120713.8 | 2007-11-14 | ||
| US99006607P | 2007-11-26 | 2007-11-26 | |
| US60/990,066 | 2007-11-26 | ||
| PCT/EP2008/065186 WO2009062898A1 (en) | 2007-11-14 | 2008-11-10 | New synthetic arginine substituted peptides and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101878226A CN101878226A (zh) | 2010-11-03 |
| CN101878226B true CN101878226B (zh) | 2014-06-25 |
Family
ID=39226731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200880114504.9A Expired - Fee Related CN101878226B (zh) | 2007-11-14 | 2008-11-10 | 精氨酸取代的新型合成肽及其应用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7928185B2 (enExample) |
| EP (2) | EP2060586A1 (enExample) |
| JP (1) | JP2011503137A (enExample) |
| CN (1) | CN101878226B (enExample) |
| AU (1) | AU2008323041A1 (enExample) |
| CA (1) | CA2703894A1 (enExample) |
| DK (1) | DK2212352T3 (enExample) |
| MX (1) | MX2010005280A (enExample) |
| WO (1) | WO2009062898A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2481751A1 (en) | 2011-01-26 | 2012-08-01 | PharmaSurgics in Sweden AB | Human lactoferrin derived peptides |
| WO2014090905A1 (en) * | 2012-12-11 | 2014-06-19 | Imaxio | Modified coiled coil type proteins having improved properties |
| JP2016520534A (ja) | 2013-03-18 | 2016-07-14 | イマクシオImaxio | インフルエンザ核タンパク質ワクチン |
| US9850278B2 (en) | 2013-04-25 | 2017-12-26 | Carmel-Haifa University Economic Corp. | Synthetic anti-inflammatory peptides and use thereof |
| US12295990B2 (en) | 2018-11-09 | 2025-05-13 | The Wistar Institute Of Anatomy And Biology | Use of lactoferrin for generating myeloid-derived suppressor cells |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1362969A (zh) * | 1999-02-05 | 2002-08-07 | 埃吉尼克斯股份有限公司 | 抗微生物/中和内毒素的多肽 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2818056B2 (ja) | 1990-09-07 | 1998-10-30 | 森永乳業株式会社 | 抗菌性ペプチドおよび抗菌剤 |
| US5656591A (en) | 1992-01-23 | 1997-08-12 | Morinaga Milk Industry Co., Ltd. | Antimicrobial agents and method for treating products therewith |
| JP3347819B2 (ja) | 1993-06-28 | 2002-11-20 | 森永乳業株式会社 | 抗菌性ペプチドの精製方法 |
| JP3529423B2 (ja) | 1994-04-01 | 2004-05-24 | 森永乳業株式会社 | 抗菌性ペプチドの製造方法 |
| JP3812957B2 (ja) | 1994-08-02 | 2006-08-23 | 森永乳業株式会社 | 角膜損傷治療剤 |
| JPH08143468A (ja) | 1994-11-17 | 1996-06-04 | Morinaga Milk Ind Co Ltd | 抗潰瘍剤 |
| JP2001504447A (ja) | 1996-08-12 | 2001-04-03 | エイプラス サイエンス インベスト アーベー | ラクトフェリンおよび/またはラクトフェリシンでの、感染、炎症および/または腫瘍の処置および予防 |
| SE9804614A0 (en) * | 1998-07-06 | 2000-01-07 | A+ Science Invest Ab | New peptides and use thereof |
| CA2388910C (en) * | 1999-11-11 | 2008-10-07 | Am-Pharma B.V. | Antimicrobial activity of the first cationic cluster of human lactoferrin |
| US7183381B2 (en) | 2004-10-26 | 2007-02-27 | Agennix, Inc. | Composition of lactoferrin related peptides and uses thereof |
-
2007
- 2007-11-14 EP EP07120713A patent/EP2060586A1/en not_active Withdrawn
-
2008
- 2008-11-10 JP JP2010533548A patent/JP2011503137A/ja active Pending
- 2008-11-10 DK DK08850370.1T patent/DK2212352T3/da active
- 2008-11-10 US US12/292,030 patent/US7928185B2/en not_active Expired - Fee Related
- 2008-11-10 WO PCT/EP2008/065186 patent/WO2009062898A1/en not_active Ceased
- 2008-11-10 AU AU2008323041A patent/AU2008323041A1/en not_active Abandoned
- 2008-11-10 MX MX2010005280A patent/MX2010005280A/es active IP Right Grant
- 2008-11-10 CA CA2703894A patent/CA2703894A1/en not_active Abandoned
- 2008-11-10 CN CN200880114504.9A patent/CN101878226B/zh not_active Expired - Fee Related
- 2008-11-10 EP EP08850370.1A patent/EP2212352B1/en not_active Not-in-force
-
2011
- 2011-04-19 US US13/089,680 patent/US8815812B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1362969A (zh) * | 1999-02-05 | 2002-08-07 | 埃吉尼克斯股份有限公司 | 抗微生物/中和内毒素的多肽 |
Non-Patent Citations (2)
| Title |
|---|
| E.W.Odell,et al.Antibacterial activity of peptides homologous to a loop region in human lactoferrin.《FEBS letters》.1996,第382卷175-178. * |
| P.H.C.van Berkel,et al.N-terminal stretch Arg2,Arg3,Arg4 and Arg5 of human lactoferrin is essential for binding to heparin,bacterial lipopolysaccharide,human lysozyme and DNA.《Biochemical Journal》.1997,第328卷145-151. * |
Also Published As
| Publication number | Publication date |
|---|---|
| DK2212352T3 (da) | 2014-09-29 |
| EP2212352A1 (en) | 2010-08-04 |
| CN101878226A (zh) | 2010-11-03 |
| US20090186823A1 (en) | 2009-07-23 |
| US8815812B2 (en) | 2014-08-26 |
| MX2010005280A (es) | 2010-08-31 |
| CA2703894A1 (en) | 2009-05-22 |
| EP2060586A1 (en) | 2009-05-20 |
| AU2008323041A1 (en) | 2009-05-22 |
| US7928185B2 (en) | 2011-04-19 |
| US20110224152A1 (en) | 2011-09-15 |
| WO2009062898A1 (en) | 2009-05-22 |
| JP2011503137A (ja) | 2011-01-27 |
| EP2212352B1 (en) | 2014-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CI01 | Publication of corrected invention patent application |
Correction item: Inventor Correct: PHARMASURGICS IN SWEDEN AB|Dolphin Gunnar False: Mattsby-baltzer Inger|Dolphin Gunnar Number: 44 Volume: 26 |
|
| CI02 | Correction of invention patent application |
Correction item: Inventor Correct: PHARMASURGICS IN SWEDEN AB|Dolphin Gunnar False: Mattsby-baltzer Inger|Dolphin Gunnar Number: 44 Page: The title page Volume: 26 |
|
| ERR | Gazette correction |
Free format text: CORRECT: INVENTOR; FROM: MATTSBY-BALTZER; DOLPHIN GUNNAR TO: MATTSBY-BALTZER INGER; DOLPHIN GUNNAR |
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| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1149769 Country of ref document: HK |
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| ASS | Succession or assignment of patent right |
Owner name: PEGAMA COMPANY Free format text: FORMER OWNER: PHARMASURGICS IN SWEDEN AB Effective date: 20121116 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20121116 Address after: Solna, Sweden Applicant after: PharmaSurgics in Sweden AB Address before: Gothenburg Applicant before: Pharmasurgics In Sweden AB |
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| ASS | Succession or assignment of patent right |
Owner name: MATTSBY-BALTZER INGER Free format text: FORMER OWNER: PERGAMA COMPANY Effective date: 20131017 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20131017 Address after: Gothenburg Applicant after: PHARMASURGICS IN SWEDEN AB Address before: Solna, Sweden Applicant before: PharmaSurgics In Sweden AB |
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| CF01 | Termination of patent right due to non-payment of annual fee |
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| CF01 | Termination of patent right due to non-payment of annual fee |