CN101869646A - External patch preparation for treating climacteric syndrome of women and preparation method thereof - Google Patents
External patch preparation for treating climacteric syndrome of women and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an external patch preparation for treating climacteric syndrome of women and a preparation method thereof and relates to a Chinese medicinal patch and a preparation method thereof. 25 to 35 mass parts of root of rehmannia, 25 to 35 mass parts of common yam rhizome, 15 to 25 mass parts of common macrocarpium fruit, 15 to 25 mass parts of oriental waterplantain rhizome, 15 to 25 mass parts of poria, 15 to 25 mass parts of cortex moutan, 15 to 25 mass parts of tulip, 25 to 35 mass parts of processed tuber fleeceflower root, 15 to 25 mass parts of epimedium, 15 to 25 mass parts of common curculigo rhizome, 10 to 20 mass parts of human placenta and 15 to 25 mass parts of desertliving cistanche are subjected to the steps of extraction, preparation, emulsification and the like to prepare the external patch preparation. The external patch preparation is a pure Chinese medicinal preparation, cannot cause multiple tumors and osteoporosis and has the advantages of targeted administration on kidney and ovary, large application amount, strong medicinal effect and sensitive effect.
Description
Technical field
The present invention relates to Chinese herbs paste and preparation method thereof, say it is a kind of outer paste preparation for the treatment of climacteric syndrome and preparation method thereof in detail.
Background technology
We know that climacteric is that women's ovarian function fails to an excessive phase of complete obiteration gradually from vigorous state, comprise a period of time of menopause and menopause front and back, and the traditional Chinese medical science is referred to as " syndrome in menopause ".Climacteric, the variation of a series of physiology and psychological aspects can appear in the women.Most women can spend climacteric reposefully, but the minority women is also arranged since climacteric physiology and mental change bigger, perplexed by a series of symptom, influence healthy.Therefore each has arrived involutional women, all will note strengthening self health care, guarantees to spend smoothly this period of life turnover, avoids bringing unnecessary trouble to family and society.No matter climacteric begin sooner or later, history how long, totally be divided into premenopause, menopause (ischomenia) and postmenopause (ischomenia is more than 1 year) and with ovarian function fail gradually to complete obiteration be sign.Climacteric is that the women progresses into senile transition stage from period of sexual maturity (period of duration), and it is an important and tangible especially stage of physiological change in the human senility process.Symptom in various degree can appear in the women more than 90%, influences personal health and quality of life.Concrete manifestation: about 30 years old: mottle obviously appears in skin, and is lax, dark and gloomy unglazed, corse sweat pore, and coarse, acne constantly waits the women of abnormality; 30-40 is between year: endocrine regulation occurs, obviously fail the women who subtracts weak person and menopause syndrome occurs as secondary diseases of women such as menoxenia, mastoptosis, nourishing YIN drying, hyposexualitys; 40-55 is between year: the women who menopause syndrome such as insomnia, dreaminess, night sweat, hectic fever, irritated irritability, energy physically-draining, hypomnesis, osteoporosis occur.More than 55 years old: renal function declines to a great extent, the middle and aged women of the basic atrophy of ovary.Usually postmenopausal women following four big symptoms can occur climacteric: hectic fever-and be the symptom that climacteric women often meets with; Cardiopalmus-just is nervous, also is climacteric one of modal symptom; Spirit, nervous symptoms performance are unusually; Sore waist and aching in the waist and the back-be the osteoporotic early symptom of climacteric women.Climacteric disease harm: the women was to spend after menopause 1/3rd times.If problem can torment own for a long time and torment others, endanger very big.Vascular dysfunctions: tactical deployment of troops disease flushing and hectic fever, feel chest, cervical region and facial heating, perspiration, fear of cold suddenly, sometimes with cardiopalmus, uncomfortable in chest, breathe hard, symptom such as dizzy.Menoxenia: menstrual cycle begins disorder before the menopause, and menostaxis increases even metrorrhagia through blood volume, but some women's cycle stretch-out reduces later ischomenia, the atrophy gradually owing to estrogenic minimizing of sexual organ and secondary sex characteristics gradually through blood volume.Spirit, nervous symptoms: climacteric women often has worry, depression, emotional, insomnia, cries well, and hypomnesis is absent-minded etc., being happy and angry uncertainly sometimes, similar phrenoplegia.Hyposexuality: pubes and axillary trichomadesis, hyposexuality, vaginal secretions reduces, and occurs pain during sexual intercourse, causes the sexual life number of times to reduce or detest the generation of sexual life emotion then.Tumor is easily sent out: climacteric is the age occurred frequently of kinds of tumor, and common have cervical cancer, an ovarian tumor etc.If can find earlier that early treatment can improve therapeutic effect and patient's survival rate.At present western medicine does not also have ideal method, and it is also very serious to regulate multiple tumor and the osteoporosis brought with complementing estrogen.2002, pass in government and various circles of society pours down, set up in Beijing by the Chinese women research on anti-senescence center that several 10 the senior academys of the most authoritative medical research institute of China " China Academy of TCM " form, be devoted to study the basic reason and the fastest best Therapeutic Method of Women.Discover that kidney, ovary play decisive role in the process that female aging changes, both are closely related, and are indispensable.Have only by the foster nest of the kidney invigorating and carry out simultaneously, be only unique approach.Ovary is supported in the kidney invigorating, and oral administration has two disasters, and the one, oral medicine is passed through blood circulation again through absorbing, and through the chemical combination of liver, through the filtration of kidney, kidney and ovary are given in reallocation, are very long processes, and it is few that these internal organs are awarded medicine.The 2nd, very moment is long more medicine time, and Drug resistance is strong more.Effect is insensitive, and the patient will be more vexed.
Summary of the invention
The technical problem that the present invention solves is, the invention provides a kind of pure Chinese medicinal preparation, can not bring multiple tumor and osteoporosis, to kidney, the medication of ovary targeting, it is big to award dose, strong drug action, outer paste preparation of the sensitive treatment climacteric syndrome of effect and preparation method thereof.
Technical scheme of the present invention is:
A kind of outer paste preparation for the treatment of climacteric syndrome is characterized in that: be processed into by crude drug (by proportion by weight) Radix Rehmanniae 25-35 part, Rhizoma Dioscoreae 25-35 part, Fructus Corni 15-25 part, Rhizoma Alismatis 15-25 part, Poria 15-25 part, Cortex Moutan 15-25 part, Flos Tulipae Gesnerianae 15-25 part, Radix Polygoni Multiflori Preparata 25-35 part, Herba Epimedii 15-25 part, Rhizoma Curculiginis 15-25 part, Placenta Hominis 10-20 part, Herba Cistanches 15-25 part.
The external application formulation preparation method of treatment climacteric syndrome is:
1, chooses crude drug by proportion by weight;
2, the Radix Rehmanniae, Rhizoma Dioscoreae, Fructus Corni, Rhizoma Alismatis powder are broken to the 20-30 order, add the clear water of 6 times of medicated powder weight, 0.3 times Sal, room temperature soaked 24 hours down, and the concentration that adds medicated powder weight 0.4-0.5 times then is 98% ethanol, room temperature lixiviate 6-7 days is filtered to such an extent that medicated wine is stand-by;
3, Poria, Cortex Moutan, Flos Tulipae Gesnerianae, Herba Cistanches are crushed to the 30-40 order, adding medicated powder weight 7-8 clear water, 0.3-0.4 white sugar room temperature doubly doubly soaked 24 hours down, the concentration that adds medicated powder weight 0.5-0.6 times then is 95% ethanol, and room temperature lixiviate 6-7 days is filtered to such an extent that medicated wine is stand-by;
4, Radix Polygoni Multiflori, Herba Epimedii, Rhizoma Curculiginis, Placenta Hominis are crushed to the 40-50 order, adding medicated powder weight 7-8 clear water, 0.3-0.4 concentration doubly doubly and be 80% white vinegar room temperature soaked 24 hours down, the concentration that adds medicated powder weight 0.5%-0.6% times then is 85% ethanol, room temperature lixiviate 6-7 days is filtered to such an extent that medicated wine is stand-by;
5, medicated wine, the medicated wine in the 3rd step, the medicated wine merging in the 4th step in the 2nd step are mixed thoroughly, pack in the blend tank, add medicated wine gross weight 0.03-0.04 Borneolum Syntheticum, 0.12-0.15 propylene glycol, 0.8-0.9 glycerol, 0.03-0.04 Tween 80 or OP doubly doubly doubly doubly
10, 0.06-0.07 methylcellulose doubly, stir compound;
6, the compound in the 5th step is packed in the emulsion tank, be warming up to 40-50 ℃, stirring and emulsifying 30 minutes is cooled to 20 degree sealings, parked 24 hours mammilary bodies;
7, mammilary bodies is crossed the nanometer fine grinding, encapsulated manufactured goods behind the porphyrize.
The invention has the beneficial effects as follows the Radix Rehmanniae: heat clearing away, promote the production of body fluid, removing heat from blood, moisturize, laxation, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving, regulating menstruation, incised wound blood stasis, cooling blood for hemostasis; The Radix Rehmanniae Preparata enriching yin and nourishing kidney, menstruation regulating blood nourishing medicinal, headache due to deficiency of blood, liver pain.Have clearing away heat and cooling blood, be used for the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, high fever coma, xerostomia crimson tongue; Control the epidemic febrile disease later stage, waste heat to the greatest extent, do not hinder, night fever abating at dawn by cloudy liquid; Can be used for controlling epidemic febrile disease, heat is gone into nutrient blood, and heat in blood poison is contained, hematemesis and epistaxis, and macule is purple black, and the YIN nourishing and the production of body fluid promoting effect is used to soak part thirsty, and interior-heat is quenched one's thirst; Control the epidemic febrile disease impairment of YIN, the dryness of the intestine constipation.Rhizoma Dioscoreae: have strengthening the spleen and tonifying the lung, the stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney is smart, and clever knowledge helps the five internal organs bone and muscle strengthening, and long will is calmed the nerves life lengthening; Cure mainly weakness of the spleen and stomach, lassitude, inappetence, chronic diarrhea and dysentery, insufficiency of lung-QI is dry, the phlegm dyspnea cough, the kidney qi loss, soreness of the waist and knees, a little less than the lower limb flaccidity, the frequent micturition of quenching one's thirst, the seminal emission premature ejaculation, the leukorrhagia nebulousurine, skin is red swollen, diseases such as obesity.Fructus Corni: liver and kidney tonifying, essence astringing and desertion stemming; Be used for vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, the urine enuresis collapses the urine leukorrhagia frequently, the profuse sweating collapse, interior-heat is quenched one's thirst.Rhizoma Alismatis: promoting diuresis to eliminate damp pathogen, it is treating stranguria to expel the heat-evil; Main dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission." medicine justice " Rhizoma Alismatis, the poorest sluice way that oozes, the urine of specially passing through.The growth marshy land; " medicine justice " all genus rush down disease, and little water must short number, with this clear and rich lung qi, and regulating fluid apssage, following defeated bladder cures mainly the watery diarrhea dairrhea caused by pathogenic damp.Make and defecate in fact, then temper is from being good for also.Because of the energy dredging water passages, make evil water go, then true water must be supported, and can end so quench one's thirst.Again can be except that damp and hot, treating stranguria drop divides the feeling of fullness that disappears, and saturating three warmers accumulation of heat is cut off the water, and this is diuretic first product.Poria: eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming; Cure mainly: dysuria, edema distension; The phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite is had loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine; The diuretic dissipating fluid-retention, spleen-benefiting mind-tranquilizing.Cortex Moutan: the removing heat from blood that purifies the blood, promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases is sent out speckle, tells nosebleed, cloudy heating, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, traumatic pain, the rheumatism pyretic arthralgia of dividing.Radix Curcumae: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice; Be used for the amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, the calentura coma, epilepsy is gone mad, the jaundice dark coloured urine.Herba Cistanches: kidney-replenishing, benefiting essence-blood, intestine moistening is just.Be used for sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, the dryness of the intestine constipation.Radix Polygoni Multiflori Preparata: enrich and benefit essence and blood, black beard and hair, bone and muscle strengthening, invigorating the liver and kidney is used for blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body void.Herba Epimedii: kidney-replenishing strengthening bone and muscle, wind-damp dispelling; Be used for impotence and seminal emission, a little less than the muscles and bones flaccidity, rheumatic arthralgia, numbness contracture.Rhizoma Curculiginis: the kidney warming sun, strengthening bone and muscle; Control the sexual impotence cold sperm, urinary incontinence, metrorrhagia, trusted subordinate's cold type of pain, cold arthralgia of loins and legs, carbuncle, scrofula, the yang deficiency cold diarrhea, sexual impotence is smart cold, and the waist knee joint is air-cooled, muscles and bones flaccidity syndrome and arthralgia syndrome etc.Placenta Hominis: the kidney invigorating and essence nourishing, the merit of benefiting QI and nourishing blood; Modern medicine thinks that Placenta Hominis contains protein, sugar, and calcium, immune factors such as vitamin, estrogen, gravidity assisting ketone, steroid hormone, promoting sexual gland hormone, thyroliberin etc. can promote growths such as mammary gland, uterus, intestinal, ovary.The outer paste preparation of the treatment climacteric syndrome of making by the above-mentioned raw materials medicine, the compound recipe effect of drug matching is given full play in pure Chinese medicine preparation, can not bring multiple tumor and osteoporosis, to kidney, the medication of ovary targeting, it is big to award dose, strong drug action, the effect sensitivity.Be used for the treatment of climacteric syndrome.
The specific embodiment
Embodiment 1
A kind of outer paste preparation for the treatment of climacteric syndrome is processed into by crude drug (by proportion by weight) Radix Rehmanniae 25-35 part, Rhizoma Dioscoreae 25-35 part, Fructus Corni 15-25 part, Rhizoma Alismatis 15-25 part, Poria 15-25 part, Cortex Moutan 15-25 part, Flos Tulipae Gesnerianae 15-25 part, Radix Polygoni Multiflori Preparata 25-35 part, Herba Epimedii 15-25 part, Rhizoma Curculiginis 15-25 part, Placenta Hominis 10-20 part, Herba Cistanches 15-25 part.
Its preparation method is:
1, chooses crude drug by proportion by weight: 25 parts in the Radix Rehmanniae, 35 parts of Rhizoma Dioscoreaes, 15 parts of Fructus Corni, 25 parts of Rhizoma Alismatis, 15 parts in Poria, 25 parts of Cortex Moutans, 15 parts of Flos Tulipae Gesnerianaes, 35 parts of Radix Polygoni Multiflori Preparatas, 15 parts of Herba Epimedii, 25 parts of Rhizoma Curculiginises, 10 parts of Placenta Hominiss, 25 parts of Herba Cistanches;
2, the Radix Rehmanniae, Rhizoma Dioscoreae, Fructus Corni, Rhizoma Alismatis powder are broken to the 20-30 order, add the clear water of 6 times of medicated powder weight, 0.3 times Sal, room temperature soaked 24 hours down, and the concentration that adds medicated powder weight 0.4-0.5 times then is 98% ethanol, room temperature lixiviate 6-7 days is filtered to such an extent that medicated wine is stand-by;
3, Poria, Cortex Moutan, Flos Tulipae Gesnerianae, Herba Cistanches are crushed to the 30-40 order, adding medicated powder weight 7-8 clear water, 0.3-0.4 white sugar room temperature doubly doubly soaked 24 hours down, the concentration that adds medicated powder weight 0.5-0.6 times then is 95% ethanol, and room temperature lixiviate 6-7 days is filtered to such an extent that medicated wine is stand-by;
4, Radix Polygoni Multiflori, Herba Epimedii, Rhizoma Curculiginis, Placenta Hominis are crushed to the 40-50 order, adding medicated powder weight 7-8 clear water, 0.3-0.4 concentration doubly doubly and be 80% white vinegar room temperature soaked 24 hours down, the concentration that adds medicated powder weight 0.5%-0.6% times then is 85% ethanol, room temperature lixiviate 6-7 days is filtered to such an extent that medicated wine is stand-by;
5, medicated wine, the medicated wine in the 3rd step, the medicated wine in the 4th step in the 2nd step is mixed and mix thoroughly, pack in the blend tank, add medicated wine gross weight 0.03-0.04 Borneolum Syntheticum, 0.12-0.15 propylene glycol, 0.8-0.9 glycerol, 0.03-0.04 Tween 80 or OP doubly doubly doubly doubly
10, 0.06-0.07 methylcellulose doubly, stir compound;
6, the compound in the 5th step is packed in the emulsion tank, be warming up to 40-50 ℃, stirring and emulsifying 30 minutes is cooled to 20 degree sealings, parked 24 hours mammilary bodies;
7, mammilary bodies is crossed the nanometer fine grinding, encapsulated manufactured goods behind the porphyrize.
Embodiment 2:
The preparation method of the outer paste preparation of treatment climacteric syndrome is:
Choose crude drug by proportion by weight: 30 parts in the Radix Rehmanniae, 30 parts of Rhizoma Dioscoreaes, 20 parts of Fructus Corni, 20 parts of Rhizoma Alismatis, 20 parts in Poria, 20 parts of Cortex Moutans, 20 parts of Flos Tulipae Gesnerianaes, 30 parts of Radix Polygoni Multiflori Preparatas, 20 parts of Herba Epimedii, 20 parts of Rhizoma Curculiginises, 15 parts of Placenta Hominiss, 20 parts of Herba Cistanches
Other steps are identical with embodiment 1, repeat no more.
Embodiment 3:
The preparation method of the outer paste preparation of treatment climacteric syndrome is:
Choose crude drug by proportion by weight: 35 parts in the Radix Rehmanniae, 25 parts of Rhizoma Dioscoreaes, 25 parts of Fructus Corni, 15 parts of Rhizoma Alismatis, 25 parts in Poria, 15 parts of Cortex Moutans, 25 parts of Flos Tulipae Gesnerianaes, 25 parts of Radix Polygoni Multiflori Preparatas, 25 parts of Herba Epimedii, 15 parts of Rhizoma Curculiginises, 20 parts of Placenta Hominiss, 15 parts of Herba Cistanches
Other steps are identical with embodiment 1, repeat no more.
Procedure of processing of the present invention can fully be extracted each raw material the effective elements of the medicine, and the drug molecular structure in the final outer paste preparation that obtains can reach the nanometer footpath of skin absorbs.During use, this outer paste preparation spread upon make patch on the matrix, be affixed on shirtfront and back, every day 1-2 time, each 4-6 hour.This outer paste preparation is given full play to the compound recipe effect of drug matching, and pure Chinese medicine preparation can not bring multiple tumor and osteoporosis, and to kidney, the medication of ovary targeting, it is big to award dose, strong drug action, effect sensitivity.Through clinical statistics, use this outer paste preparation more than 30 days, effective percentage 78%.
Claims (2)
1. an outer paste preparation for the treatment of climacteric syndrome is characterized in that: be processed into by crude drug (by proportion by weight) Radix Rehmanniae 25-35 part, Rhizoma Dioscoreae 25-35 part, Fructus Corni 15-25 part, Rhizoma Alismatis 15-25 part, Poria 15-25 part, Cortex Moutan 15-25 part, Flos Tulipae Gesnerianae 15-25 part, Radix Polygoni Multiflori Preparata 25-35 part, Herba Epimedii 15-25 part, Rhizoma Curculiginis 15-25 part, Placenta Hominis 10-20 part, Herba Cistanches 15-25 part.
2. the outer paste preparation of treatment climacteric syndrome according to claim 1 is characterized in that preparation method is:
(1), chooses crude drug by proportion by weight;
(2), the Radix Rehmanniae, Rhizoma Dioscoreae, Fructus Corni, Rhizoma Alismatis powder are broken to the 20-30 order, add the clear water of 6 times of medicated powder weight, 0.3 times Sal, room temperature soaked 24 hours down, and the concentration that adds medicated powder weight 0.4-0.5 times then is 98% ethanol, room temperature lixiviate 6-7 days is filtered to such an extent that medicated wine is stand-by;
(3), Poria, Cortex Moutan, Flos Tulipae Gesnerianae, Herba Cistanches are crushed to the 30-40 order, adding medicated powder weight 7-8 clear water, 0.3-0.4 white sugar room temperature doubly doubly soaked 24 hours down, the concentration that adds medicated powder weight 0.5-0.6 times then is 95% ethanol, and room temperature lixiviate 6-7 days is filtered to such an extent that medicated wine is stand-by;
(4), Radix Polygoni Multiflori, Herba Epimedii, Rhizoma Curculiginis, Placenta Hominis are crushed to the 40-50 order, adding medicated powder weight 7-8 clear water, 0.3-0.4 concentration doubly doubly and be 80% white vinegar room temperature soaked 24 hours down, the concentration that adds medicated powder weight 0.5%-0.6% times then is 85% ethanol, room temperature lixiviate 6-7 days is filtered to such an extent that medicated wine is stand-by;
(5), medicated wine, the medicated wine in the 3rd step, the medicated wine in the 4th step in the 2nd step is mixed and mix thoroughly, pack in the blend tank, add medicated wine gross weight 0.03-0.04 Borneolum Syntheticum, 0.12-0.15 propylene glycol, 0.8-0.9 glycerol, 0.03-0.04 Tween 80 or OP doubly doubly doubly doubly
10, 0.06-0.07 methylcellulose doubly, stir compound;
(6), the compound in the 5th step is packed in the emulsion tank, be warming up to 40-50 ℃, stirring and emulsifying 30 minutes is cooled to 20 degree sealings, parked 24 hours mammilary bodies;
(7), mammilary bodies the nanometer fine grinding excessively, encapsulate manufactured goods behind the porphyrize.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102755521A (en) * | 2012-07-31 | 2012-10-31 | 施慧达药业集团(吉林)有限公司 | Chinese materia medica preparation for treating climacteric syndrome and preparation method thereof |
| CN103536720A (en) * | 2013-10-18 | 2014-01-29 | 杜宏博 | Traditional Chinese medicinal composition for treating climacteric syndrome |
| CN105381116A (en) * | 2015-11-30 | 2016-03-09 | 扬州佳柔美容发展有限公司 | Nano microemulsion traditional Chinese medicine navel paste preparation and preparation method thereof |
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2010
- 2010-06-04 CN CN201010191310A patent/CN101869646A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102755521A (en) * | 2012-07-31 | 2012-10-31 | 施慧达药业集团(吉林)有限公司 | Chinese materia medica preparation for treating climacteric syndrome and preparation method thereof |
| CN102755521B (en) * | 2012-07-31 | 2014-01-29 | 施慧达药业集团(吉林)有限公司 | Chinese materia medica preparation for treating climacteric syndrome and preparation method thereof |
| CN103536720A (en) * | 2013-10-18 | 2014-01-29 | 杜宏博 | Traditional Chinese medicinal composition for treating climacteric syndrome |
| CN103536720B (en) * | 2013-10-18 | 2016-02-17 | 杜宏博 | A kind of Chinese medicine composition for the treatment of climacteric syndrome |
| CN105381116A (en) * | 2015-11-30 | 2016-03-09 | 扬州佳柔美容发展有限公司 | Nano microemulsion traditional Chinese medicine navel paste preparation and preparation method thereof |
| CN105381116B (en) * | 2015-11-30 | 2020-01-10 | 扬州佳柔美容发展有限公司 | Nano micro-emulsified Chinese medicine navel plaster preparation and its preparing method |
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Application publication date: 20101027 |