CN101869623A - Medicament for treating trichoepithelioma and preparation method thereof - Google Patents

Medicament for treating trichoepithelioma and preparation method thereof Download PDF

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CN101869623A
CN101869623A CN201010192180A CN201010192180A CN101869623A CN 101869623 A CN101869623 A CN 101869623A CN 201010192180 A CN201010192180 A CN 201010192180A CN 201010192180 A CN201010192180 A CN 201010192180A CN 101869623 A CN101869623 A CN 101869623A
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trichoepithelioma
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CN101869623B (en
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兰吉如
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Abstract

The invention discloses a medicament for treating trichoepithelioma. The medicament comprises the following raw materials in part by weight: 100 parts of bezoar, 5 to 15 parts of rehmanniae praeparatum, 4 to 16 parts of root of red-rooted salvia, 2 to 8 parts of frankincense, 2 to 8 parts of myrrh and 100 to 180 parts of solvent. The invention also discloses a preparation method of the medicament. The medicament has the effects of softening hardness to dissipate stagnation, eliminating rash and promoting tissue regeneration and dispelling the trichoepithelioma.

Description

A kind of medicine for the treatment of trichoepithelioma and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of trichoepithelioma, also relate to the preparation method of this medicine.
Background technology
The traditional Chinese medical science does not have the corresponding name of disease of trichoepithelioma.The dialectical stagnation of QI knot that surely belongs to the liver lung, qi and blood stagnation stagnates and gathers this disease of formation of a specified duration.The rule of treatment should be with soothing the liver reason lung, blood circulation promoting and blood stasis dispelling, and hard masses softening and resolving, it is main eliminating the trichoepithelioma pimple.Trichoepithelioma have the most refractory dermatosis chronic disease appellation." treated and deeply then easily cause scar, treated shallow then easily recurrence " because of it, be the difficult problem of the domestic and international medical circle of puzzlement always.Because the trichoepithelioma root reaches papillary layer of corium deeply.And the Therapeutic Principle of skin generally is: the degree of depth must not surpass the papillary layer of corium that is called as the skin safe line.Otherwise the damage subcutaneous tissue forms permanent cicatrix.If treated shallowly, the residual root of trichoepithelioma is longer again.So, how correctly to grasp and control well the treatment degree of depth of trichoepithelioma, become one and demanded the difficult problem studying and solve urgently.At present both at home and abroad the treatment trichoepithelioma mainly adopts laser, electron ion (fulgerizing) or freezing method reaching the purpose of eliminating pathological tissues, but has many drawbacks.Mainly utilize the hyperpyrexia electric spark to burn carbonization skin lesion tissue as laser with fulgerizing, belong to traumatic treatment.Painful big when especially sensitive part around the nose being treated, the patient is difficult to stand often needs local anesthesia, and after using anesthetis, skin histology swelling distortion is difficult to accurate location, influences operation, does not reach due curative effect.Particularly above method can not correctly be grasped the treatment degree of depth, and skin of face very easily stays cicatrix.It is obvious that other shortcoming is controlled back local skin swollen tissue in addition, and pigmentation is serious.Can not get wet in one week washes one's face, and infects easily.Influence orthobiosis and work or the like.
Summary of the invention
The objective of the invention is to, overcome the deficiencies in the prior art, propose a kind of medicine for the treatment of trichoepithelioma and preparation method thereof, reach better therapeutic effect.
The technical solution used in the present invention is as follows:
A kind of medicine for the treatment of trichoepithelioma comprises the raw material of following weight ratio example: 100 parts of Calculus Boviss, Radix Rehmanniae 5-15 part, Radix Salviae Miltiorrhizae 4-16 part, Olibanum 2-8 part, Myrrha 2-8 part, solvent 100-180 part.
Preferably, also comprise the raw material of following weight ratio example: Radix Dipsaci 5-18 part, Radix Paeoniae Alba 5-15 part, Flos Carthami 4-15 part, Semen Persicae 4-17 part.
Preferably, described solvent is ethanol or white vinegar.
Preferably, comprise the raw material of following weight ratio example: 100 parts of Calculus Boviss, 15 parts in the Radix Rehmanniae, 15 parts on Flos Carthami, 17 parts in Semen Persicae, 16 parts of Radix Salviae Miltiorrhizaes, 8 parts of Olibanums, 8 parts of Myrrhas, 15 parts of the Radix Paeoniae Albas, 18 parts of Radix Dipsacis, 180 parts of white vinegars.
A kind of preparation method for the treatment of the medicine of trichoepithelioma comprises the steps:
1., get the Radix Rehmanniae, Radix Salviae Miltiorrhizae, Olibanum and Myrrha, be ground into coarse powder;
2., coarse powder was soaked for 2 weeks with solvent.Flood then and percolation, collect percolate;
3., Calculus Bovis be ground into impalpable powder join in the percolate, stir, soaked for 2 weeks;
4., stock solution is concentrated into 20-25%, medicine.
Preferably, each raw material that relates in the preparation method adds by following part by weight: 100 parts of Calculus Boviss, Radix Rehmanniae 5-15 part, Radix Salviae Miltiorrhizae 4-16 part, Olibanum 2-8 part, Myrrha 2-8 part, solvent 100-180 part.
Preferably, step 1. in, the raw material of adding also comprises Radix Dipsaci, the Radix Paeoniae Alba, Flos Carthami and Semen Persicae.
Preferably, each raw material that relates in the preparation method adds by following part by weight: 100 parts of Calculus Boviss, Radix Rehmanniae 5-15 part, Radix Salviae Miltiorrhizae 4-16 part; Olibanum 2-8 part, Myrrha 2-8 part, solvent 100-180 part, Radix Dipsaci 5-18 part; Radix Paeoniae Alba 5-15 part, Flos Carthami 4-15 part, Semen Persicae 4-17 part.
Preferably, described solvent is ethanol or white vinegar.
Preferably, each raw material that relates in the preparation method adds by following part by weight: 100 parts of Calculus Boviss, 15 parts in the Radix Rehmanniae, 15 parts on Flos Carthami, 17 parts in Semen Persicae, 16 parts of Radix Salviae Miltiorrhizaes, 8 parts of Olibanums, 8 parts of Myrrhas, 15 parts of the Radix Paeoniae Albas, 18 parts of Radix Dipsacis, 180 parts of white vinegars.
Beneficial effect of the present invention is, this medicine has softening the hard mass, eliminating stagnation, invigorates blood circulation, blood stasis dispelling, eliminates the pimple effect.This medicine can infiltrate into the trichoepithelioma root on the papillary layer of corium rapidly downwards, makes tumor body protein sample solidify atrophy, loses vigor and absorbs trophic function.Forming thin crust comes off voluntarily.It is normal that skin recovers.In therapeutic process, the Calculus Bovis crystal solution is utilized the own barrier action of skin, and the degree of depth accurately is controlled on the papillary layer of corium, does not damage subcutaneous tissue, so can not form cicatrix.The conscience gallbladder meridian is gone in the bitter sweet cold of Calculus Bovis in this prescription.Function: clear away heart-fire and reduce phlegm, function of gallbladder promoting is relieving convulsion, analgesic eliminating the phlegm, sensible avoiding evil spirits.Because Calculus Bovis has heat-clearing and toxin-vanquishing, cooling blood, expelling wind, is apt to control all sore swollen toxins, so be usually used in treating all kinds of dermatosis." Standards of Diagnosis and Treatment ": Calculus Bovis ... control infantile carbuncle furuncle and all skin infection." Shengji Zonglu " Calculus Bovis ... control breast carcinoma (breast carcinoma), bubo, scrofula, sucutaneous nodule, multiple abscess, lung abscess ....We are principal agent with the Calculus Bovis.Have blood-activating and qi-promoting with the Radix Rehmanniae, Radix Salviae Miltiorrhizae, Radix Paeoniae, Olibanum, Myrrha, Flos Carthami, Semen Persicae etc., medicines such as eliminating stasis and resolving masses, dredge the meridian passage are associated with.Utilize white vinegar acid to receive, soaking quenches gets the elite of all property of medicine that neutralizes.We are secret recipe handed down in the family.Through clinical practice for many years, treatment trichoepithelioma curative effect is reliable.Be a kind ofly be better than laser, fulgerize, refrigerated, have the automatic control treatment degree of depth, no wound, no cicatrix, no pain get wet and do not infect, and be safe and efficient, the good method of simple and convenient treatment trichoepithelioma.
The specific embodiment
The Calculus Bovis crystal solution is by forming by weight being prepared by following raw materials according: 100 parts of Calculus Boviss, 15 parts in the Radix Rehmanniae, 15 parts on Flos Carthami, 17 parts in Semen Persicae, 16 parts of Radix Salviae Miltiorrhizaes, 8 parts of Olibanums, 8 parts of Myrrhas, 15 parts of the Radix Paeoniae Albas, 18 parts of Radix Dipsacis, 180 parts of white vinegars.
Another kind of manner of formulation is: 100 parts of Calculus Boviss, 5 parts in the Radix Rehmanniae, 4 parts on Flos Carthami, 4 parts in Semen Persicae, 4 parts of Radix Salviae Miltiorrhizaes, 2 parts of Olibanums, 2 parts of Myrrhas, 5 parts of the Radix Paeoniae Albas, 5 parts of Radix Dipsacis, 100 parts of ethanol.
The third manner of formulation is: 100 parts of Calculus Boviss, 10 parts in the Radix Rehmanniae, 10 parts on Flos Carthami, 10 parts in Semen Persicae, 10 parts of Radix Salviae Miltiorrhizaes, 6 parts of Olibanums, 6 parts of Myrrhas, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Dipsacis, 150 parts of white vinegars.
The preparation process of Calculus Bovis crystal solution comprises the steps:
1., get the Radix Rehmanniae, crude drug such as Radix Salviae Miltiorrhizae, Radix Dipsaci, the Radix Paeoniae Alba, Flos Carthami, Semen Persicae, Olibanum and Myrrha are ground into coarse powder;
2., the coarse powder solvent was soaked for 2 weeks.Flood then and percolation, collect percolate;
3., Calculus Bovis be ground into impalpable powder join in the percolate, stir, soaked for 2 weeks.
4., stock solution is concentrated into 20-25%, medicine: the Calculus Bovis crystal solution.
This medical instrument has hard masses softening and resolving, and the rash that disappears granulation promoting is dispeled the effect of trichoepithelioma.
Medication: the patient gets dorsal position, and the doctor wears glove, behind the routine disinfection affected part, and left hand taught skin, fixedly trichoepithelioma pimple.The right hand is held the special for treating rod that speckles with the Calculus Bovis crystal solution, medicinal liquid is accurately put be applied on the trichoepithelioma body.Scope does not exceed the about 0.5mm in tumor body edge.Medicine solidifies trichoepithelioma rapidly, forms albuminoid degeneration.After several minutes, the tumor body begins atrophy, and illing skin flattens, and trichoepithelioma disappears.Treatment back skin is intact, and cleaning is dry, and no wound need not wrapping.Can get wet washes one's face has a bath, and does not influence orthobiosis.Treat that trichoepithelioma becomes thin crust after 1-2 days.Withered the coming off in 1~2 week back, it is smooth smooth that skin recovers, and trichoepithelioma heals entirely.Can there be temporary pigmentation the part, and thin out gradually in the future disappearing recovers the normal colour of skin.
The clinical efficacy contrast:
60 routine patients are all from outpatient service.In January, 2006-2009 time year December.Male's 12 examples wherein, women's 48 examples.Age: from 8 years old to 48 years old.Course of disease 1-30.The patient is divided into two groups at random, Calculus Bovis crystal solution treatment group and CO2 laser matched group.
Curative effect determinate standard:
Recovery from illness: pimple all disappears, and it is good that skin recovers.
Produce effects: pimple obviously diminishes, and skin recovers.
Take a turn for the better: pimple diminishes, and skin recovers better.
Invalid: pimple and skin do not have obvious improvement.
Two groups of treatment trichoepithelioma Comparison of therapeutic tables [example (%)]
Figure BSA00000152926600051
Can find out that from above contrast table treatment group cure rate is 241% of a matched group, significantly exceeds the matched group curative effect.And matched group causes scar formation rate up to 66.6%.The treatment group is 0% causing on the scar formation rate, and the contrast tool has great advantage.

Claims (10)

1. medicine for the treatment of trichoepithelioma comprises the raw material of following weight ratio example: 100 parts of Calculus Boviss, Radix Rehmanniae 5-15 part, Radix Salviae Miltiorrhizae 4-16 part, Olibanum 2-8 part, Myrrha 2-8 part, solvent 100-180 part.
2. medicine as claimed in claim 1 is characterized in that, also comprises the raw material of following weight ratio example: Radix Dipsaci 5-18 part, Radix Paeoniae Alba 5-15 part, Flos Carthami 4-15 part, Semen Persicae 4-17 part.
3. medicine as claimed in claim 1 or 2 is characterized in that, described solvent is ethanol or white vinegar.
4. medicine as claimed in claim 3 is characterized in that, comprises the raw material of following weight ratio example: 100 parts of Calculus Boviss, 15 parts in the Radix Rehmanniae, 15 parts on Flos Carthami, 17 parts in Semen Persicae, 16 parts of Radix Salviae Miltiorrhizaes, 8 parts of Olibanums, 8 parts of Myrrhas, 15 parts of the Radix Paeoniae Albas, 18 parts of Radix Dipsacis, 180 parts of white vinegars.
5. the preparation method of the medicine of treatment trichoepithelioma comprises the steps:
1., get the Radix Rehmanniae, Radix Salviae Miltiorrhizae, Olibanum and Myrrha, be ground into coarse powder;
2., coarse powder was soaked for 2 weeks with solvent, flood then and percolation, collect percolate;
3., Calculus Bovis be ground into impalpable powder join in the percolate, stir, soaked for 2 weeks;
4., stock solution is concentrated into 20-25%, medicine.
6. preparation method as claimed in claim 5 is characterized in that, each raw material that relates in the preparation method adds by following part by weight: 100 parts of Calculus Boviss, Radix Rehmanniae 5-15 part, Radix Salviae Miltiorrhizae 4-16 part, Olibanum 2-8 part, Myrrha 2-8 part, solvent 100-180 part.
7. preparation method as claimed in claim 5 is characterized in that, step 1. in, the raw material of adding also comprises Radix Dipsaci, the Radix Paeoniae Alba, Flos Carthami and Semen Persicae.
8. preparation method as claimed in claim 7; it is characterized in that each raw material that relates in the preparation method adds by following part by weight: 100 parts of Calculus Boviss, Radix Rehmanniae 5-15 part; Radix Salviae Miltiorrhizae 4-16 part; Olibanum 2-8 part, Myrrha 2-8 part, solvent 100-180 part; Radix Dipsaci 5-18 part; Radix Paeoniae Alba 5-15 part, Flos Carthami 4-15 part, Semen Persicae 4-17 part.
9. as each described preparation method in the claim 5 to 8, it is characterized in that described solvent is ethanol or white vinegar.
10. preparation method as claimed in claim 9 is characterized in that, each raw material that relates in the preparation method adds by following part by weight: 100 parts of Calculus Boviss, 15 parts in the Radix Rehmanniae; 15 parts on Flos Carthami, 17 parts in Semen Persicae, 16 parts of Radix Salviae Miltiorrhizaes, 8 parts of Olibanums; 8 parts of Myrrhas, 15 parts of the Radix Paeoniae Albas, 18 parts of Radix Dipsacis, 180 parts of white vinegars.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579677A (en) * 2012-04-08 2012-07-18 许从玉 Chinese medicinal composition for treating brain glioma

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101530468A (en) * 2008-03-14 2009-09-16 北京汉潮联创中药科技有限公司 Chinese medicinal preparation for treating gum cancer

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101530468A (en) * 2008-03-14 2009-09-16 北京汉潮联创中药科技有限公司 Chinese medicinal preparation for treating gum cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
《江西中医药》 19951231 于永源 治癌痛之体会 27-28页 1-10 , *
《江西中医药》 19951231 于永源 治癌痛之体会 27-28页 1-10 , 2 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579677A (en) * 2012-04-08 2012-07-18 许从玉 Chinese medicinal composition for treating brain glioma
CN102579677B (en) * 2012-04-08 2013-09-11 李伟丽 Chinese medicinal composition for treating brain glioma

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