CN101862439A - Anti-inflammatory throat lozenge containing natural Zingiber corallinum Hance essential oil - Google Patents

Anti-inflammatory throat lozenge containing natural Zingiber corallinum Hance essential oil Download PDF

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Publication number
CN101862439A
CN101862439A CN201010102991A CN201010102991A CN101862439A CN 101862439 A CN101862439 A CN 101862439A CN 201010102991 A CN201010102991 A CN 201010102991A CN 201010102991 A CN201010102991 A CN 201010102991A CN 101862439 A CN101862439 A CN 101862439A
Authority
CN
China
Prior art keywords
parts
essential oil
excipient
zingiber corallinum
corallinum hance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201010102991A
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Chinese (zh)
Inventor
谢家祥
谢涛
唐京生
白涛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LINGFANG BIOLOGICAL TECHNOLOGY Co Ltd CHONGQING
Original Assignee
LINGFANG BIOLOGICAL TECHNOLOGY Co Ltd CHONGQING
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by LINGFANG BIOLOGICAL TECHNOLOGY Co Ltd CHONGQING filed Critical LINGFANG BIOLOGICAL TECHNOLOGY Co Ltd CHONGQING
Priority to CN201010102991A priority Critical patent/CN101862439A/en
Publication of CN101862439A publication Critical patent/CN101862439A/en
Priority to CN2010105610763A priority patent/CN102008693B/en
Pending legal-status Critical Current

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  • Medicines Containing Plant Substances (AREA)
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Abstract

The invention provides an anti-inflammatory throat lozenge containing natural Zingiber corallinum Hance essential oil which has reliable effects of antibiosis, antiphlogosis, detumescence and analgesia, short treatment period, simple and practical preparation method and low cost. The preparation method comprises the following steps: weighting 1-5 parts of natural Zingiber corallinum Hance essential oil, 10-20 parts of honeysuckle concrete, 8-12 parts of taste-modifying sugar, 63-81 parts of excipient and 10-20 parts of sterile water by weight, then heating sterile water, taste-modifying sugar and honeysuckle concrete commonly for dissolving and boiling, cooling to 35-45 DEG C, adding Zingiber corallinum Hance essential oil to stir evenly, adding excipient to stir evenly, placing the mixture in a forming machine, and drying to obtain the finished product. The anti-inflammatory throat lozenge has broad antibacterial spectrum, has the functions of antiphlogosis, detumescence and analgesia, and can improve microcirculatory disturbance and improve the stimulus threshold to poor factors and self-renewing ability of the tissue cells of the throat; and the lozenge takes effect fast, and has short treatment period, high recovery rate, simple and practical preparation method and low cost.

Description

The antiinflammatory buccal tablet that wets one's whistle that contains natural Zingiber corallinum Hance essential oil
Technical field
The present invention relates to a kind of antiinflammatory buccal tablet that wets one's whistle, the particularly a kind of prevention of natural Zingiber corallinum Hance essential oil and antiinflammatory buccal tablet that wets one's whistle of treatment laryngopharynx swelling and pain of containing.
Background technology
Laryngopharynx swelling and pain is because physics, chemistry, biology, body illness factor such as bring out infects pharyngolaryngeal mucosa, the tolerance threshold value that surpasses this position mucosa, cause tela submucosa blood capillary spasm, hyperemia, hemorrhage, bring out a kind of illness of infection, occur red, swollen, hot, bitterly, a series of inflammatory reactions such as microcirculation disturbance.As malpractice, make that the pain increased, hypopnea, dysphagia has a strong impact on physical and mental health, quality of life, study and work.The existing antiinflammatory buccal tablet that wets one's whistle is of a great variety, and the emphasis different treatment effects also has nothing in common with each other, and the antibacterial effect that has is poor, and the antiinflammatory that has, analgesic effect do not show.
Summary of the invention
The antiinflammatory buccal tablet that wets one's whistle that the invention provides that a kind of antibiotic, antiinflammatory, detumescence, analgesic effect are all reliable, short treating period, the simple and easy to do low cost of preparation method contains natural Zingiber corallinum Hance essential oil.
The technical scheme that adopts is as follows:
Earlier take by weighing various raw materials: 1~5 part of natural Zingiber corallinum Hance essential oil, 10~20 parts of Flos Lonicerae extractums, 8~12 parts of flavoring sugar, 63~81 parts of excipient, 10~20 parts of aquesterilisa by following parts by weight; Aquesterilisa and flavoring sugar, Flos Lonicerae extractum heating is molten to boiling, to be cooled to 35~45 ℃ altogether, add Rhizoma Zingiberis corallini quintessence oil and stir, it is even to drop in the excipient mix, drops in the moulding stamper machine that oven dry gets final product after the moulded section again.
Various raw material weight umbers scope preferably are: 2~4 parts of Rhizoma Zingiberis corallini quintessence oil, 12~15 parts of Flos Lonicerae extractums, 8~12 parts of flavoring sugar, 63~81 parts of excipient, 12~18 parts of aquesterilisa.
The present invention is different from prior art: with natural Zingiber corallinum Hance essential oil, Flos Lonicerae extractum is main prevention, treatment composition, and makes by described method, and except that Rhizoma Zingiberis corallini quintessence oil was supplied with by our company, all the other raw materials all can be buied from market.Correctives can be xylitol, sucrose, maltose etc., and excipient can be starch, flour, rice meal etc.
Rhizoma Zingiberis corallini quintessence oil is the extract of Chinese herbal medicine Rhizoma Zingiberis corallini, is a kind of good efficiency natural antibacterial, the tool broad-spectrum antibacterial action, and to the bacteriostatic experiment of the penicillin-fast golden Fructus Vitis viniferae of 30 strains, 28 strains are to the Rhizoma Zingiberis corallini quintessence oil sensitivity through Rhizoma Zingiberis corallini quintessence oil, responsive rate 93.3%.Modern medicine study confirms, Rhizoma Zingiberis corallini quintessence oil can suppress the pain writhing response that acetic acid causes and the edema due to the Oleum Tiglii is oozed out and the capillary permeability of hydrion due to stimulating increases, have antiinflammatory, subside a swelling, eliminate the phlegm, analgesic activity, can remove the inflammation edema, the microcirculation improvement obstacle, improve the stimulus threshold of body, quicken the histiocytic self renewal of inflammation part, the eliminating phlegm and relieving asthma effect is arranged simultaneously the bad factor.The used Rhizoma Zingiberis corallini quintessence oil of the present invention derives from our company and prepares voluntarily.Preparation method is: be raw material with the Rhizoma Zingiberis corallini, adopt supercritical carbon dioxide extraction or steam distillation to make that (supercritical extraction gained Rhizoma Zingiberis corallini quintessence oil keeps former this flavor of medicine better, steam distillation gained Rhizoma Zingiberis corallini quintessence oil is abnormal flavour slightly, but impact effects not).
Flos Lonicerae extractum, its Main Ingredients and Appearance is a chlorogenic acid, has broad-spectrum antibacterial action.Preparation method is: with the Flos Lonicerae coarse pulverization, add water logging and do not have the powder digestion three times, kept to boiling 1 hour at every turn, merge three times filtrate, the cooling back adds equivalent ethanol (95%) precipitation, filters, filtrate is at 60 ℃ of left and right sides reclaim under reduced pressure ethanol, concentrates and promptly get that (every 1ml concentrated solution is equivalent to the former medicine of Flos Lonicerae and is not less than 1 and restrains.)
The wet one's whistle using method of antiinflammatory buccal tablet of the present invention: containing clothes in mouthful, daily 2~3 times.As prevent, stimulated by the bad factor before i.e. containing clothes.Serve on healing in 3~5 days.Containing of health care, day clothes get final product for 1 time.Informal dress, many clothes have no adverse reaction cure rate 100%.
Throat lozenge of the present invention has carried out clinical practice to routine patient surplus 150, prevention, evident in efficacy, and cure rate reaches 100%, does not see untoward reaction.
The beneficial effect of throat lozenge of the present invention is that bactericidal effect is remarkable, possesses antiinflammatory, Repercusion analgesia function simultaneously, uses the back instant effect, cures height, has no side effect.Raw material and manufacturing cost are cheap, and preparation is simple.
Specific embodiment (totally 4 examples)
Embodiment 1:
Earlier take by weighing various raw materials: natural Zingiber corallinum Hance essential oil 5kg, Flos Lonicerae extractum 20kg, flavoring sugar (xylitol) 12kg, excipient (starch) 81kg by following weight; Aquesterilisa 10kg and xylitol, Flos Lonicerae extractum heating is molten to boiling, to be cooled to 45 ℃ altogether, add Rhizoma Zingiberis corallini quintessence oil and stir, drop into that fully mix is even in the excipient, drop into again in the moulding stamper machine that oven dry gets final product after the moulded section.
Embodiment 2:
Earlier take by weighing various raw materials: natural Zingiber corallinum Hance essential oil 1kg, Flos Lonicerae extractum 10kg, flavoring sugar (xylitol) 8kg, excipient (rice meal) 63kg by following parts by weight; Aquesterilisa 12kg and xylitol, Flos Lonicerae extractum heating is molten to boiling, to be cooled to 35 ℃ altogether, add Rhizoma Zingiberis corallini quintessence oil and stir, it is even to drop in the starch mix, drops in the moulding stamper machine that oven dry gets final product after the moulded section again.
Embodiment 3:
Earlier take by weighing various raw materials: natural Zingiber corallinum Hance essential oil 2kg, Flos Lonicerae extractum 12kg, sucrose 10kg, flour 70kg by following parts by weight; Aquesterilisa 20kg and xylitol, Flos Lonicerae extractum heating is molten to boiling, to be cooled to 40 ℃ altogether, add Rhizoma Zingiberis corallini quintessence oil and stir, it is even to drop in the starch mix, drops in the moulding stamper machine that oven dry gets final product after the moulded section again.
Embodiment 4
Earlier take by weighing various raw materials: natural Zingiber corallinum Hance essential oil 4kg, Flos Lonicerae extractum 15kg, xylitol 11kg, starch 75kg by following parts by weight; Aquesterilisa 18kg and xylitol, Flos Lonicerae extractum heating is molten to boiling, to be cooled to 42 ℃ altogether, add Rhizoma Zingiberis corallini quintessence oil and stir, it is even to drop in the excipient mix, drops in the moulding stamper machine that oven dry gets final product after the moulded section again.

Claims (3)

1. antiinflammatory buccal tablet that wets one's whistle that contains natural Zingiber corallinum Hance essential oil, it is characterized in that being prepared as follows: take by weighing various raw materials by following parts by weight earlier: 1~5 part of natural Zingiber corallinum Hance essential oil, 10~20 parts of Flos Lonicerae extractums, 8~12 parts of flavoring sugar, 63~81 parts of excipient, 10~20 parts of aquesterilisa; Aquesterilisa and flavoring sugar, Flos Lonicerae extractum heating is molten to boiling, to be cooled to 35~45 ℃ altogether, add Rhizoma Zingiberis corallini quintessence oil and stir, it is even to drop in the excipient mix, drops in the moulding stamper machine that oven dry gets final product after the moulded section again.
2. the antiinflammatory buccal tablet that wets one's whistle that contains natural Zingiber corallinum Hance essential oil as claimed in claim 1, wherein various raw materials in part by weight are: 2~4 parts of Rhizoma Zingiberis corallini quintessence oil, 12~15 parts of Flos Lonicerae extractums, 10~11 parts of flavoring sugar, 70~75 parts of excipient, 12~18 parts of aquesterilisa.
3. the antiinflammatory buccal tablet that wets one's whistle that contains natural Zingiber corallinum Hance essential oil as claimed in claim 1, wherein said flavoring sugar is xylitol, excipient is a starch.
CN201010102991A 2010-01-29 2010-01-29 Anti-inflammatory throat lozenge containing natural Zingiber corallinum Hance essential oil Pending CN101862439A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201010102991A CN101862439A (en) 2010-01-29 2010-01-29 Anti-inflammatory throat lozenge containing natural Zingiber corallinum Hance essential oil
CN2010105610763A CN102008693B (en) 2010-01-29 2010-11-19 Throat-moistening and inflammation-eliminating buccal tablets containing natural essential oil of zingiber corallinum hance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201010102991A CN101862439A (en) 2010-01-29 2010-01-29 Anti-inflammatory throat lozenge containing natural Zingiber corallinum Hance essential oil

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CN101862439A true CN101862439A (en) 2010-10-20

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CN2010105610763A Active CN102008693B (en) 2010-01-29 2010-11-19 Throat-moistening and inflammation-eliminating buccal tablets containing natural essential oil of zingiber corallinum hance

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106260984A (en) * 2015-05-20 2017-01-04 张俊 A kind of manufacture method of Rhizoma Zingiberis Recens buccal tablet

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106260984A (en) * 2015-05-20 2017-01-04 张俊 A kind of manufacture method of Rhizoma Zingiberis Recens buccal tablet

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Publication number Publication date
CN102008693A (en) 2011-04-13
CN102008693B (en) 2011-12-07

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Open date: 20101020