CN101862381A - Traditional Chinese medicine compound having function of curing anemia and preparation method thereof - Google Patents
Traditional Chinese medicine compound having function of curing anemia and preparation method thereof Download PDFInfo
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- CN101862381A CN101862381A CN200910079052A CN200910079052A CN101862381A CN 101862381 A CN101862381 A CN 101862381A CN 200910079052 A CN200910079052 A CN 200910079052A CN 200910079052 A CN200910079052 A CN 200910079052A CN 101862381 A CN101862381 A CN 101862381A
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Abstract
The invention discloses a traditional Chinese medicine compound having a function of curing anemia and a preparation method thereof. The traditional Chinese medicine compound is prepared by proportioning Angelica sinensis, Astragalus mongholicus, red dates and peanut kernel according to weight proportion. The traditional Chinese medicine compound of the invention has the function of curing anemia.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition of improving the anemia function and preparation method thereof that has.Belong to medicine and field of health care food.
Background technology
Anemia is meant the subnormal pathological state of hemoglobin content, RBC number and packed cell volume in the unit volume blood circulation, and the whole blood volume minimizing, and the syndromic general name that causes therefrom.Anemia has shortage property anemia, congenital anemia, hemopoietic organ obstacle, noxious substance the occur anemia that causes, the anemia that causes substantially.The kind difference of anemia, the method for treatment is also completely different.Anemia is a kind of commonly encountered diseases, is not a kind of independently disease, and is higher in China anemia patient's ratio.
The general non-highlands of China, non-adult male, hemoglobin concentration is lower than 120g/L, and RBC number is lower than 4 * 1012/L, or packed cell volume is lower than 0.40; Adult female's hemoglobin concentration is lower than 105g/L, RBC number is lower than 3.5 * 1012/L or erythrocyte forces down in 0.35, it is more lower slightly than man normal value to can be considered following child of anemia .12 year, can allow at most to reduce about 15%, the both sexes no significant difference. occupy the highlands person for a long time, because anoxia hemopoietic, its every index value are then slightly high.In having or not on this point of measurement anemia, among this three of hemoglobin concentration, RBC number and packed cell volume, being lower than with hemoglobin concentration normally is the most basic important indicator, because it more can reflect the essence of anemia.Whether accurately reflection exists or the degree of anemia and RBC number differs surely under certain conditions. such as, when microcytic hypochromic anemia, it is lighter that the RBC number purpose reduces the degree that lowers than hemoglobin, so that anemia is when light, and red blood cell count(RBC) still can be normal; On the contrary, during the maxicell anemia, the minimizing of red blood cell count(RBC) is more more remarkable than the degree that hemoglobin lowers, when red blood cell count(RBC) a little less than just often, hemoglobin concentration can be still in normal range. the degree of anemia, generally can divide by the degree that hemoglobin concentration lowers: be lower than normal but 90g/L and above person thereof for slight; Lower, but be moderate at 60g/L and above person thereof; Or lower, but be severe at 30g/L and above person thereof; Be lower than 30g/L and above person thereof and be the extreme anemia.In addition, false anemia except noting. as exist gestation or liver cirrhosis etc. to make when water retention causes plasma volume to increase in the body, even the whole body red blood cell volume is normal, but measured RBC number and hemoglobin concentration also can lower, otherwise easily think anemia by mistake., if when having obvious dehydration hyperamization slurry capacity to reduce, even anemia is arranged, measured erythrocyte and hemoglobin concentration may be normal. and when judging anemia, these factors all should be noted.
The title that does not have anemia in the Chinese medicine, genus " insufficiency of vital energy and blood " is thought in treatment often.Generally anemia can be put under the category of " blood deficiency " or " asthenia exhaustion of blood ", and " asthenia " is the general name of multiple chronic disease due to internal organs losss, the vigour weakness.
Summary of the invention
The object of the invention just provides a kind of Chinese medicine composition that improves the anemia function that has.
Another object of the present invention has provided the preparation method of this Chinese medicine composition.
The present invention is achieved by the following technical solutions:
The present invention is made by the following weight proportion raw material:
Radix Angelicae Sinensis 6～12g, the Radix Astragali 9～30g, Fructus Jujubae 6～15g, Semen arachidis hypogaeae 6～15g
Be preferably:
Radix Angelicae Sinensis 10g, Radix Astragali 20g, Fructus Jujubae 10g, Semen arachidis hypogaeae 10g
The preparation method of Chinese medicine composition of the present invention is as follows:
Get Radix Angelicae Sinensis, the Radix Astragali, Fructus Jujubae, Semen arachidis hypogaeae, add ethanol and extract, extracting solution is concentrated, drying makes dry extract, adds appropriate amount of auxiliary materials, mixing, and drying is made granule.
The preferred for preparation method of Chinese medicine composition of the present invention is as follows:
Get Radix Angelicae Sinensis, the Radix Astragali, Fructus Jujubae, Semen arachidis hypogaeae, add 8 times of amount 60% ethanol extractions 2 times, each 2 hours, extracting liquid filtering, filtrate decompression are concentrated into the extractum that relative density is 1.25～1.30 (55 ℃), add 3～5 times of water gaging precipitations, get the supernatant concentrating under reduced pressure, drying makes dry extract, be ground into fine powder, cross 80 mesh sieves, add an amount of dextrin, sucrose, evenly mixed, adding ethanol is wetting agent, granulates, drying, granulate is made granule.
Each drug mechanism is as follows among the present invention:
Radix Angelicae Sinensis: Radix Angelicae Sinensis sweet in the mouth, suffering, warm in nature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, diseases such as ulcer sores.Radix Angelicae Sinensis can be enriched blood, be invigorated blood circulation, again can regulating menstruation, and be the key medicine of enriching blood, be again gynecological's key medicine.Be used for blood deficiency or blood deficiency and have the menoxenia that the stasis of blood stagnates, dysmenorrhea, diseases such as amenorrhea concurrently; Holding concurrently again can dispersing cold for relieving pain, is used for blood deficiency, stasis and have cold coagulation concurrently, and traumatic injury, the pain card of wind-damp numbness.Modern times are used for angina pectoris, thromboangiitis obliterans etc., also obtain certain curative effect.Radix Angelicae Sinensis can the promoting blood circulation and detumescence pain relieving, again can tonic blood and growing muscle, so also used always by the surgery ulcer sores.Its enriching blood for moistening the intestine relieving constipation effect is used for the constipation of blood deficiency dryness of the intestine.
Motherland's medical science thinks, Radix Angelicae Sinensis sweet in the mouth and weighing, so specially can enrich blood, its gas is light and hot, thus again can promoting the circulation of blood, invigorating middle warmer has, benefit is arranged in capable, is the key medicine in the blood.Thereby it can be enriched blood, and can invigorate blood circulation again, both can stimulate the menstrual flow, again can be active.All menoxenias, dysmenorrhea, the blood deficiency amenorrhea, shallow complexion, weak anemia, metrorrhagia, postnatal blood stasis, example can be used angelica for treating through women's such as (during menstrual onset, mouth and nose occur and bleed) commonly encountered diseases.
The Radix Astragali: Radix Astragali sweet in the mouth, warm in nature.Return lung, spleen channel.Has invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, the effect of expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
The Radix Astragali is a tonic.Right its property is kind moving, and row has the machine of sending out that rises concurrently about inside and outside the exterior and the interior.But, outwards inspire healthy energy to pass through inside with poison holding at the table invigorating QI to consolidate the body surface resistance; The lining then in invigorating middle warmer gas with ascending up spleen-Qi and Yang, make " gas-solid and fall into from remove "; Upwards then gas lift water falls certainly with QI invigorating diuretic, tonifying QI to promote blood circulation.The Radix Astragali has the title of gas medicine in the blood again, so but hemopoietic, right gas is congested real, and the open sore part of bursting must be held back for a long time, so but promoting tissue regeneration and ulcer healing again.
The Radix Astragali is not only the key medicine of QI invigorating, can by QI invigorating with hemopoietic, gas is prosperous receives the effect of enriching blood with hemopoietic, simultaneously, this product also has the good merit of enriching blood.Just proposing this product as far back as " Japan hanako materia medica " can " enrich blood ", also mentions energy " hemopoietic " in the essentials of Matea Medica, and " book on Chinese herbal medicine meets former " calls its " all void of energy tonifying five ZANG-organs ", and this had both comprised the deficiency of vital energy of tonifying five ZANG-organs, comprised the blood deficiency of tonifying five ZANG-organs again.Be used for from making of tradition side's medicine, the Radix Astragali is very extensive as the use of hematonic, all reusing the Radix Astragali in many prescriptions of enriching blood is principal agent, Radix Angelicae Sinensis decoction for tonifying blood as " differentiation on endogenous ", " secret record of the orchid chamber. on the volume " in rename as astragalus, angelica soup, and the name of the Radix Astragali is preced with first of the prescription, is listed in before the Radix Angelicae Sinensis, this explanation author pays much attention to the status of the Radix Astragali in this prescription.In addition " obstetrics' heart method. volume down " in the book, the prescription of the Radix Astragali and Radix Angelicae Sinensis two medicines composition is called " Radix Astragali blood-enriching soup ", just in the Radix Astragali as monarch drug, consumption is five times in Radix Angelicae Sinensis with controlling all cards of blood deficiency.The prescription that also has a large amount of prescriptions directly to name in the ancient prescription with the nourishing blood function of the Radix Astragali, as " dialectical record. roll up 12 " Radix Astragali blood-enriching soup, the amount of the Radix Astragali is twice in Radix Angelicae Sinensis in the side; " Elementary Medicine. volume seven " Radix Astragali blood-enriching soup etc.With the Radix Astragali and based on the prescription of all cards of compound treatment blood deficiency of the Radix Astragali, too numerous to enumerate in the ancient prescription.Modern times are also many clinically to be main with this product, is equipped with the product of enriching blood, and is used for the treatment of leukopenia due to anemia, leukopenia and tumor radiotherapy, the chemotherapy, chronic granulocytopenia etc.
Fructus Jujubae: the Fructus Jujubae sweet in the mouth, warm in nature.Return spleen, stomach warp.The tool invigorating the spleen and replenishing QI, the effect of nourishing blood to tranquillize the mind.Be used for insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria.Nutritional labelings such as Fructus Jujubae rich in proteins, fat, saccharide, carotene, vitamin B group, vitamin C, Citrin and calcium, phosphorus, ferrum and cyclic adenosine monophosphate.Wherein ascorbic content comes out at the top in fruit, and vitamin king's laudatory title is arranged.The cyclic adenosine monophosphate that Fructus Jujubae contained is the essential composition of human body cell energy metabolism, can muscle strength reinforcing, allaying tiredness, blood vessel dilating, increase myocardial contraction, improve myocardial nutrition, the control cardiovascular system diseases there is good effect.The Chinese medicine theory is thought, Fructus Jujubae has effects such as tonify deficiency QI invigorating, nourishing blood to tranquillize the mind, invigorating the spleen and regulating the stomach, be patient's good health care nutriments such as weakness of the spleen and stomach, insufficiency of vital energy and blood, lassitude, insomnia and dreamful sleep, simultaneously in tcm prescription, Fructus Jujubae is a simply modal integration of edible and medicinal herbs side medicine, and its nourishing blood function is also become a much-told tale always.But Fructus Jujubae except invigorating the spleen and replenishing QI, the effect of enriching blood in addition.Have stronger tonic effect, can improve immune function of human body, strengthen resistance against diseases.
Semen arachidis hypogaeae: the effect of Semen arachidis hypogaeae tool the spleen and stomach regulating, tonifying blood and arresting bleeding, hypertension and hyperlipemia.Theory of Chinese medical science is thought, " The spleen governs the blood ", the people of the deficiency of vital energy is just hemorrhage easily, exactly because the gas that Testa arachidis hypogaeae can tonifying the spleen and stomach, so can reach the effect of nourishing blood and hemoslasis, this says on the traditional Chinese medical science and is " hemostasis by invigorating QI ".The effect of Semen arachidis hypogaeae " tonifying blood and arresting bleeding " mainly is exactly the contribution of outer that layer scarlet of Semen arachidis hypogaeae.Doctor trained in Western medicine thinks that Testa arachidis hypogaeae can suppress fibrinous dissolving, and the content of platelet increasing improves hematoblastic quality, improves the defective of thrombin, strengthens the contraction function of blood capillary, promotes the bone marrow hematogenesis function.So diseases such as the various hemorrhage and hemorrhage anemias that cause, aplastic anemia are had positive effect.
In the drug composition, enrich blood, help with QI invigorating when invigorating blood circulation in the present invention.The traditional Chinese medical science thinks that blood is tangible thing, and gas belongs to invisible usefulness.The operation of blood depends on gas, thus have " qi as the commander of blood, the capable then blood of gas is capable, blood being the mother of qi, blood to gas also to " theory.Blood is given birth to by gas, and gas also must have blood for depending on the effect of its biochemistry of competence exertion, motion.The two interdepends, and promotes mutually again, keeps relative equilibrium.If qi-blood disharmony, will cause a disease.This side meets theory of Chinese medical science, has reached the effect of QI and blood with benefit.
The specific embodiment
Embodiment 1:
The preparation of Chinese medicine composition of the present invention:
A) get Radix Angelicae Sinensis 10kg, Radix Astragali 20kg, Fructus Jujubae 10kg, Semen arachidis hypogaeae 10kg, standby;
B), add 8 times of amount 60% ethanol extractions 2 times, each 2 hours with above-mentioned four Chinese medicine;
C) extracting liquid filtering, filtrate are concentrated into the extractum that relative density is 1.25～1.30 (55 ℃);
D) aqueous precipitation;
E) get the supernatant concentrating under reduced pressure, drying makes dry extract;
F) be ground into fine powder, cross 80 mesh sieves;
G) add an amount of dextrin, sucrose, evenly mixed;
H) adding ethanol is wetting agent, granulate, and drying, granulate is made granule.
Embodiment 2:
The preparation of Chinese medicine composition of the present invention:
A) get Radix Angelicae Sinensis 10kg, Radix Astragali 20kg, Fructus Jujubae 10kg, Semen arachidis hypogaeae 10kg, standby;
B), add 8 times of amount 70% ethanol extractions 2 times, each 2 hours with above-mentioned four Chinese medicine;
C) extracting liquid filtering, filtrate are concentrated into the extractum that relative density is 1.15～1.25 (55 ℃);
D) aqueous precipitation;
E) get the supernatant concentrating under reduced pressure, drying makes dry extract;
F) be ground into fine powder, cross 80 mesh sieves;
G) add an amount of dextrin, sucrose, evenly mixed;
H) adding ethanol is wetting agent, granulate, and drying, granulate is made granule.
Embodiment 3:
The preparation of Chinese medicine composition of the present invention:
A) get Radix Angelicae Sinensis 10kg, Radix Astragali 20kg, Fructus Jujubae 10kg, Semen arachidis hypogaeae 10kg, standby;
B), add 6 times of amount 80% ethanol extractions 3 times, each 1.5 hours with above-mentioned four Chinese medicine;
C) extracting liquid filtering, filtrate are concentrated into the extractum that relative density is 1.20～1.30 (55 ℃);
D) aqueous precipitation;
E) get the supernatant concentrating under reduced pressure, drying makes dry extract;
F) be ground into fine powder, cross 80 mesh sieves;
G) add an amount of dextrin, sucrose, evenly mixed;
H) adding ethanol is wetting agent, granulate, and drying, granulate is made granule.
Claims (5)
1. one kind has the Chinese medicine composition that improves the anemia function, it is characterized in that, this Chinese medicine composition is to be made by following medicinal materials in weight portion: Radix Angelicae Sinensis 6～12g, the Radix Astragali 9～30g, Fructus Jujubae 6～15g, Semen arachidis hypogaeae 6～15g.
2. pharmaceutical composition according to claim 1 is characterized in that, said composition is to be made by following medicinal materials in weight portion: Radix Angelicae Sinensis 10g, Radix Astragali 20g, Fructus Jujubae 10g, Semen arachidis hypogaeae 10g.
3. claim 1 or 2 described preparation of drug combination methods is characterized in that this method is:
Radix Angelicae Sinensis, the Radix Astragali, Fructus Jujubae, Semen arachidis hypogaeae with described weight proportion add ethanol and extract, and extracting solution is concentrated, and drying makes dry extract, add appropriate amount of auxiliary materials, mixing, and drying is made granule.
4. according to the described preparation of drug combination method of claim 3, it is characterized in that this method is:
Get Radix Angelicae Sinensis, the Radix Astragali, Fructus Jujubae, Semen arachidis hypogaeae, add 8 times of amount 60% ethanol extractions 2 times, each 2 hours, extracting liquid filtering, filtrate decompression are concentrated into the extractum that relative density is 1.25～1.30 (55 ℃), add 3～5 times of water gaging precipitations, get the supernatant concentrating under reduced pressure, drying makes dry extract, be ground into fine powder, cross 80 mesh sieves, add an amount of dextrin, sucrose, evenly mixed, adding ethanol is wetting agent, granulates, drying, granulate is made granule.
5. claim 1 or 2 described Chinese medicine compositions are used to prepare the application that improves anemia.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302118A (en) * | 2011-08-18 | 2012-01-04 | 天津大学 | Astragalus and Chinese date instant granules and preparation method thereof |
| CN102308950A (en) * | 2011-08-06 | 2012-01-11 | 黄月红 | Nutritional breakfast |
| CN103284044A (en) * | 2013-06-20 | 2013-09-11 | 林学聪 | Lactation promotion paste health food preparation method |
| CN103549419A (en) * | 2013-10-30 | 2014-02-05 | 四川大学 | Qi tonifying and blood nourishing micro-nano particle health-care granules and preparation method thereof |
-
2009
- 2009-03-04 CN CN200910079052A patent/CN101862381A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102308950A (en) * | 2011-08-06 | 2012-01-11 | 黄月红 | Nutritional breakfast |
| CN102302118A (en) * | 2011-08-18 | 2012-01-04 | 天津大学 | Astragalus and Chinese date instant granules and preparation method thereof |
| CN103284044A (en) * | 2013-06-20 | 2013-09-11 | 林学聪 | Lactation promotion paste health food preparation method |
| CN103549419A (en) * | 2013-10-30 | 2014-02-05 | 四川大学 | Qi tonifying and blood nourishing micro-nano particle health-care granules and preparation method thereof |
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Application publication date: 20101020 |