CN101856370A - Medicine combination capable of regulating immunity - Google Patents

Medicine combination capable of regulating immunity Download PDF

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Publication number
CN101856370A
CN101856370A CN201010219281A CN201010219281A CN101856370A CN 101856370 A CN101856370 A CN 101856370A CN 201010219281 A CN201010219281 A CN 201010219281A CN 201010219281 A CN201010219281 A CN 201010219281A CN 101856370 A CN101856370 A CN 101856370A
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China
Prior art keywords
truffe
cordyceps
pharmaceutical composition
regulating immunity
medicine
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Pending
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CN201010219281A
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Chinese (zh)
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郭景龙
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Individual
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Individual
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Priority to CN201010219281A priority Critical patent/CN101856370A/en
Publication of CN101856370A publication Critical patent/CN101856370A/en
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a medicine combination containing Cordyceps sinensis and truffle, belonging to the technical field of medicine or food. The invention is characterized in that the medicine combination contains 1-10 parts of Cordyceps sinensis and 0.1-5 parts of truffle by weight. According to pharmacological tests, the medicine combination has very good immunity regulation function and can be used as healthcare food for improving immunity.

Description

A kind of pharmaceutical composition of regulating immunity
Technical field
The invention belongs to medical technical field, be specifically related to contain in a kind of raw material the pharmaceutical composition of Cordyceps and Truffe.
Background technology
Immunity is the defense mechanism of human body self, is human body identification and any foreign body (virus, antibacterial etc.) of eliminating external intrusion; Handle the ability of self cell and identification and the processing vivo mutations cell and the virus infected cell of old and feeble, damage, dead, degeneration.Modern immunology thinks that immunity is human body identification and the physiological reaction of getting rid of " dissident ".What carry out this function in the human body is immune system.Over millions of years, human at environment that not only is fit to existence but also is fraught with risks of life, the mankind are able to survival, have also obtained outstanding immunity.Immunity is the product of biological evolution process thus.
A variety of causes makes immune system normally not bring into play protective effect, in the case, very easily cause infection such as antibacterial, virus, fungus, so the most direct performance of hypoimmunity is exactly liable to illness.Because of often ill, increased the weight of the consumption of body, thus generally have a delicate constitution, performances such as malnutrition, listlessness, fatigue and weak, appetite depression, sleep disorder, sick, have an injection and take medicine the normal potluck that just gets married.Each sickly all will could recover for a long time, and usually outbreak repeatedly.If things go on like this can cause health and intelligence development bad, also easily bring out major disease.Underlying causes is that hypoimmunity or immunity are unsound.When the immune function of human body imbalance, when perhaps immune system was unsound, following point will show effect repeatedly: show effect repeatedly repeatedly, asthma is shown effect repeatedly, bronchitis shows effect repeatedly, pneumonia is shown effect repeatedly by outbreak, tonsillitis for flu, the outbreak repeatedly of suffering from diarrhoea ... so necessarily can't neglect.
Summary of the invention
For these reasons, the inventor studies by test of many times, and Cordyceps and Truffe are formed the medicine of new raising immunity, and pharmacological evaluation shows, pharmaceutical composition of the present invention has better effect than independent use Cordyceps or Truffe.
The present invention is achieved through the following technical solutions.
A kind of pharmaceutical composition of regulating immunity, crude drug comprises Cordyceps and Truffe.Crude drug also comprises one or more in tea polyphenols, lentinan, ginseng polysaccharide, the Radix Astragali, lycopene, garlicin, Lac regis apis, ganoderan, the carotene etc.
Cordyceps of the present invention can replace with fermented Cordyceps powder.Truffe of the present invention can be used the Truffe mycelium, and fermentation Truffe mycopowder replaces.
Cordyceps 1-10 weight portion wherein, Truffe is the 0.1-5 weight portion.Crude drug comprises Cordyceps and Truffe.Crude drug comprises Echinacea and fermented Cordyceps powder.Crude drug also comprises one or more in tea polyphenols, lentinan, ginseng polysaccharide, the Radix Astragali, lycopene, garlicin, Lac regis apis, ganoderan, the carotene etc.
Cordyceps of the present invention can replace with fermented Cordyceps powder.Truffe of the present invention can be used the Truffe mycelium, and fermentation Truffe mycopowder replaces.
Cordyceps 2-8 weight portion wherein, Truffe is the 0.5-3 weight portion.Crude drug comprises Cordyceps and Truffe.Crude drug comprises Echinacea and fermented Cordyceps powder.Crude drug also comprises one or more in tea polyphenols, lentinan, ginseng polysaccharide, the Radix Astragali, lycopene, garlicin, Lac regis apis, ganoderan, the carotene etc.
Cordyceps of the present invention can replace with fermented Cordyceps powder.Truffe of the present invention can be used the Truffe mycelium, and fermentation Truffe mycopowder replaces.
Cordyceps 2-5 weight portion wherein, Truffe is the 1-3 weight portion.Crude drug comprises Cordyceps and Truffe.Crude drug comprises Echinacea and fermented Cordyceps powder.Crude drug also comprises one or more in tea polyphenols, lentinan, ginseng polysaccharide, the Radix Astragali, lycopene, garlicin, Lac regis apis, ganoderan, the carotene etc.
Cordyceps of the present invention can replace with fermented Cordyceps powder.Truffe of the present invention can be used the Truffe mycelium, and fermentation Truffe mycopowder replaces.
Cordyceps 4 weight portions wherein, Truffe is 2 weight portions.Crude drug comprises Cordyceps and Truffe.Crude drug comprises Echinacea and fermented Cordyceps powder.Crude drug also comprises one or more in tea polyphenols, lentinan, ginseng polysaccharide, the Radix Astragali, lycopene, garlicin, Lac regis apis, ganoderan, the carotene etc.
Cordyceps of the present invention can replace with fermented Cordyceps powder.Truffe of the present invention can be used the Truffe mycelium, and fermentation Truffe mycopowder replaces.
The food of crude drug preparation wherein.
Wherein pharmaceutical preparation is tablet, capsule, granule, oral liquid or pill.
Wherein food is tablet, capsule, granule, oral liquid or pill.
Pharmacodynamics test
Test 1 improves immunity test
Trial drug:
1 group of medicine: Cordyceps;
2 groups of medicines: Truffe;
3 groups of medicines: Cordyceps 1g, Truffe 0.1g;
4 groups of medicines: Cordyceps 10g, Truffe 5g;
5 groups of medicines: Cordyceps 4g, Truffe 2g;
Experimental animal: male mice in kunming, body weight 18-22g.Male BALB/C mice, cleaning level, body weight 18-22g.
Test method: mice is divided into negative control group and different pharmaceutical group at random, gives distilled water and each medicine group respectively, gastric infusion, dosage 1.5g/g.The all edible full nutrition mixed feed of all experimental animals.Animal freely ingests, takes the photograph water.Inductive mouse spleen lymphocyte conversion test of concanavalin A (ConA) and the test determination of NK cytoactive adopt male BALB/C mice as experimental animal, and all the other every tests adopt male mice in kunming and Cavia porcellus as experimental animal.
Table 1MTT method (the inductive mouse spleen lymphocyte conversion test of ConA)
Group Add the ConA hole and do not add ConA hole absorbance difference
Normal group ??0.057±0.014
1 group of medicine ??0.074±0.012 *
2 groups of medicines ??0.068±0.015
3 groups of medicines ??0.093±0.041 **
Group Add the ConA hole and do not add ConA hole absorbance difference
4 groups of medicines ??0.091±0.025 **
5 groups of medicines ??0.121±0.033 **
Annotate: compare with matched group *P<0.05, *P<0.01; Compare △ P<0.05 for 1 group with medicine.
Clinical trial
Clinical diagnosis is the patient who is used for hypoimmunity, strive for that patient agrees, give Cordyceps (10g/ time/day) respectively, Truffe (10g/ time/day), the granule of medication medication compositions of the present invention (Cordyceps 8g, Truffe is 2g/ time/day) preparation, after the medication 90 days, Cordyceps group improvement rate is 81.7%, Truffe group improvement rate 75.9%, pharmaceutical composition improvement rate 95.2% of the present invention
Conclusion (of pressure testing): above-mentioned test shows, the present invention with Cordyceps and Truffe combination after, have a fine effect to having improved immunity.
Embodiment
Embodiment 1
A kind of pharmaceutical composition of regulating immunity, Cordyceps 1g wherein, Truffe is 0.1g, astragalus polysaccharides 0.04g.
According to prior art, add adjuvant, be prepared into food or medicine, its preparation is tablet, capsule, granule, oral liquid or pill.
Embodiment 2
A kind of pharmaceutical composition of regulating immunity, Cordyceps 10g wherein, Truffe is 5g, ginseng polysaccharide, garlicin be 0.7g altogether.
According to prior art, add adjuvant, be prepared into food or medicine, its preparation is tablet, capsule, granule, oral liquid or pill.
Embodiment 3
A kind of pharmaceutical composition of regulating immunity, Cordyceps 2g wherein, Truffe is 0.5g,, Lac regis apis 0.6g.
According to prior art, add adjuvant, be prepared into food or medicine, its preparation is tablet, capsule, granule, oral liquid or pill.
Embodiment 4
A kind of pharmaceutical composition of regulating immunity, Cordyceps 8g wherein, Truffe is 3g, according to prior art, adds adjuvant, is prepared into food or medicine, its preparation is tablet, capsule, granule, oral liquid or pill.
Embodiment 5
A kind of pharmaceutical composition of regulating immunity, Cordyceps 2g wherein, Truffe is 1g, according to prior art, adds adjuvant, is prepared into food or medicine, its preparation is tablet, capsule, granule, oral liquid or pill.
Embodiment 6
A kind of pharmaceutical composition of regulating immunity, Cordyceps 5g wherein, Truffe is 3g,
According to prior art, add adjuvant, be prepared into food or medicine, its preparation is tablet, capsule, granule, oral liquid or pill.
Embodiment 7
A kind of pharmaceutical composition of regulating immunity, Cordyceps 4g wherein, Truffe is 2g, according to prior art, adds adjuvant, is prepared into food or medicine, its preparation is tablet, capsule, granule, oral liquid or pill.
Embodiment 8
A kind of pharmaceutical composition of regulating immunity, Cordyceps 5g wherein, Truffe is 1.5g, ginseng polysaccharide 3g.
According to prior art, add adjuvant, be prepared into food or medicine, its preparation is tablet, capsule, granule, oral liquid or pill.

Claims (8)

1. a pharmaceutical composition of regulating immunity is characterized in that crude drug comprises Cordyceps and Truffe.
2. a kind of pharmaceutical composition of regulating immunity according to claim 1, Cordyceps 1-10 weight portion wherein, Truffe is the 0.1-5 weight portion.
3. a kind of pharmaceutical composition of regulating immunity according to claim 1, Cordyceps 2-8 weight portion wherein, Truffe is the 0.5-3 weight portion.
4. a kind of pharmaceutical composition of regulating immunity according to claim 1, Cordyceps 2-5 weight portion wherein, Truffe is the 1-3 weight portion.
5. according to each described a kind of pharmaceutical composition of regulating immunity of claim 1-4, Cordyceps 4 weight portions wherein, Truffe is 2 weight portions.
6. according to each described a kind of pharmaceutical composition of regulating immunity of claim 1-4, the food of crude drug preparation wherein.
7. according to the described a kind of pharmaceutical composition of regulating immunity of claim 5, wherein pharmaceutical preparation is tablet, capsule, granule, oral liquid or pill.
8. according to the described a kind of pharmaceutical composition of regulating immunity of claim 6, wherein food is tablet, capsule, granule, oral liquid or pill.
CN201010219281A 2010-07-07 2010-07-07 Medicine combination capable of regulating immunity Pending CN101856370A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
CN201010219281A CN101856370A (en) 2010-07-07 2010-07-07 Medicine combination capable of regulating immunity

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CN101856370A true CN101856370A (en) 2010-10-13

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102145019A (en) * 2011-03-29 2011-08-10 郭景龙 Medicinal composition containing truffles, vitamins and mineral substances
CN102224872A (en) * 2011-04-28 2011-10-26 郭景龙 Health food with truffles and coffee beans as raw materials
CN102551066A (en) * 2012-03-26 2012-07-11 张丽琴 Health-care food containing maca, cordyceps and truffle
CN102599514A (en) * 2012-03-26 2012-07-25 张丽琴 Health food containing maca and truffle
CN103549407A (en) * 2013-11-14 2014-02-05 攀枝花学院 Truffle microcapsule and preparation method and application thereof
CN110024971A (en) * 2019-04-18 2019-07-19 重庆信美金进出口有限公司 A kind of black pine sausage and preparation method thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102145019A (en) * 2011-03-29 2011-08-10 郭景龙 Medicinal composition containing truffles, vitamins and mineral substances
CN102224872A (en) * 2011-04-28 2011-10-26 郭景龙 Health food with truffles and coffee beans as raw materials
CN102551066A (en) * 2012-03-26 2012-07-11 张丽琴 Health-care food containing maca, cordyceps and truffle
CN102599514A (en) * 2012-03-26 2012-07-25 张丽琴 Health food containing maca and truffle
CN103549407A (en) * 2013-11-14 2014-02-05 攀枝花学院 Truffle microcapsule and preparation method and application thereof
CN103549407B (en) * 2013-11-14 2016-01-27 攀枝花学院 Truffle microcapsule and its preparation method and application
CN110024971A (en) * 2019-04-18 2019-07-19 重庆信美金进出口有限公司 A kind of black pine sausage and preparation method thereof

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Application publication date: 20101013

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