CN101852695B - High-flux tissue grinder - Google Patents
High-flux tissue grinder Download PDFInfo
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- CN101852695B CN101852695B CN2010101641264A CN201010164126A CN101852695B CN 101852695 B CN101852695 B CN 101852695B CN 2010101641264 A CN2010101641264 A CN 2010101641264A CN 201010164126 A CN201010164126 A CN 201010164126A CN 101852695 B CN101852695 B CN 101852695B
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Abstract
The invention discloses a high-flux tissue grinder which comprises a pedestal, at least one working frame and a driving mechanism, wherein the driving mechanism is used for driving the working frame, and the working frame and the driving mechanism are connected through a crank mechanism. The invention is characterized in that a sliding guide mechanism is arranged on the crank mechanism and has the advantages that machine damage easily caused by poor overall force balance and overall self-oscillation can be overcome, so that the whole grinder is in dynamic balance, the machine life is prolonged, and the work efficiency is improved.
Description
Technical field
The present invention relates to a kind of muller, especially relate to a kind of high-flux tissue grinder.
Background technology
High-flux tissue grinder can be used for to multiple different materials dry grind, milling and mix and the processing that homogenizes under wet-milling or the cryogenic conditions.The kind of material comprises plant tissue, animal tissue, cell, bacterium and yeast or the like.For the nucleic acid that extracts in the big flux sample, at first need sample is ground fully in the laboratory, make the tissue or the clasmatosis of sample.
At present, a kind of high-flux tissue grinder of Chinese patent and Ginding process (application number is 200910101884.9) disclose a kind of muller and have comprised pedestal, process box and the driving mechanism that is used to drive process box, after mill ball put into sample hose, sample hose is seated in the process box, driving mechanism makes driving shaft at the vertical direction double vibrations by eccentric wheel, under high-frequency vibration, mill ball impacts sample at a high speed and finishes grinding to sample, this high-flux tissue grinder has simple in structure, the advantage that the material sample grinding effect is good, but because eccentric wheel just is difficult to be transferred to and process box, sample hose and interior mill ball thereof, the comminuting matter of motion balances each other, also just can't realize dynamic mass balance, this complete machine dynamic balance is bad, and vibration very easily causes machine breakdown with complete machine self, waste and consumes energy cause inefficiency.
Summary of the invention
Technical matters to be solved by this invention provides and a kind ofly can reduce complete machine oscillation, makes complete machine be in mobile equilibrium, improves the high-flux tissue grinder of service life of a machine and work efficiency.
The present invention solves the problems of the technologies described above the technical scheme that is adopted: a kind of high-flux tissue grinder, comprise pedestal, at least one process box and be used to drive the driving mechanism of process box, described process box is connected by crank mechanism with described driving mechanism, and described crank mechanism is provided with sliding guide mechanism.
Described sliding guide mechanism comprises the slide-and-guide piece, described slide-and-guide piece is provided with central through hole, the periphery of described central through hole is provided with at least three rolling grooves, be provided with at least one rolling bearing in the described rolling groove, described rolling bearing radially parallel with the direction of described central through hole.
Described slide-and-guide piece is provided with pin-and-hole, and the direction of described pin-and-hole is vertical with the direction of described central through hole.
Described crank mechanism comprises connecting rod and slide bar, described driving mechanism comprises pair Flywheel disc that goes out spindle motor and two equals in quality, described Flywheel disc is arranged on described pair and goes out on the output shaft of spindle motor both sides, described Flywheel disc is provided with excentric shaft, described excentric shaft is fixedlyed connected with described connecting rod one end, the described connecting rod other end is connected by being coupling with described slide bar, and described slide bar passes described central through hole and is connected with described process box.
Described output shaft end is provided with first groove, and described Flywheel disc center pit is provided with second groove, and described first groove and described second groove closely cooperate by key.
The shape of cross section of described slide bar and described central through hole is a square, is provided with four rolling grooves around the described central through hole.
Substrate and outer substrate in described pedestal comprises reach described outer base lower surface between base lower surface and the described outer upper surface of base plate around the upper surface of base plate, in described in described and are provided with soft core pad all around.
Compared with prior art, the invention has the advantages that: because crank mechanism is provided with sliding guide mechanism, when process box moves reciprocatingly in vertical direction, even under high-frequency vibration, also can overcome the machine breakdown that the complete machine dynamic balance is bad and complete machine self vibration very easily causes, can reduce complete machine oscillation, make complete machine be in mobile equilibrium, improve service life of a machine and work efficiency;
Because sliding guide mechanism comprises the slide-and-guide piece, the slide-and-guide piece is provided with central through hole, the periphery of central through hole is provided with at least three rolling grooves, be provided with at least one rolling bearing in the rolling groove, rolling bearing radially parallel with the direction of central through hole, realize rolling friction by rolling bearing between driving mechanism and the sliding guide mechanism, drive process box and do double vibrations in vertical direction, reduced between driving mechanism and sliding guide mechanism because of rubbing action produces friction loss between heat and parts, prolonged instrument serviceable life;
Because the slide-and-guide piece is provided with pin-and-hole, the direction of pin-and-hole is vertical with the direction of central through hole, can insert piston pin in pin-and-hole, and piston pin passes the position that the rolling bearing endoporus is used for fixing bearing;
Because crank mechanism comprises connecting rod and slide bar, driving mechanism comprises pair Flywheel disc that goes out spindle motor and two equals in quality, Flywheel disc is arranged on and two goes out on the output shaft of spindle motor both sides, Flywheel disc is provided with excentric shaft, excentric shaft is fixedlyed connected with connecting rod one end, and the connecting rod other end is connected by being coupling with slide bar, and slide bar passes central through hole and is connected with process box, can make complete machine two ends stress balance, avoid the machine breakdown that causes because of the machine stress inequality;
Owing to output shaft end is provided with first groove, the Flywheel disc center pit is provided with second groove, and first groove and second groove closely cooperate by key, therefore pair output shaft rotation drive Flywheel disc rotation that goes out spindle motor.
Because the shape of cross section of slide bar and central through hole is a square, is provided with four rolling grooves around the central through hole, more helps slide bar and moves reciprocatingly in vertical direction;
Because substrate and outer substrate in pedestal comprises, around the interior upper surface of base plate, between interior base lower surface and the outer upper surface of base plate and outer base lower surface be provided with soft core pad all around, can be used for slowing down the high-frequency motion vibration of complete machine down, increase work efficiency thereby reduce noise.
Description of drawings
Fig. 1 is the structural drawing of a kind of high-flux tissue grinder of the present invention;
Fig. 2 is the perspective view of sliding guide mechanism of the present invention;
Fig. 3 is the cut-open view in A-A ' cross section of Fig. 2.
Embodiment
Embodiment describes in further detail the present invention below in conjunction with accompanying drawing.
Embodiment:
A kind of high-flux tissue grinder, it comprises pedestal, two process boxs 1 and is used to drive the driving mechanism of process box 1, and process box 1 is connected by crank mechanism with driving mechanism, and crank mechanism is provided with sliding guide mechanism 2.
Crank mechanism comprises connecting rod 11 and slide bar 12, driving mechanism comprises two go out spindle motor 9 and two Flywheel discs identical in quality 10, Flywheel disc 10 is arranged on two spindle motor 9 both sides output shafts that go out, Flywheel disc 10 is provided with excentric shaft 13, excentric shaft 13 is fixedlyed connected with an end of connecting rod 11, connecting rod 11 other ends are connected by being coupling with slide bar 12, slide bar 12 is connected with process box 1 by central through hole 3, wherein output shaft end is provided with first groove, Flywheel disc 10 center pits are provided with second groove, first groove and second groove closely cooperate by key, and slide bar 12 is a square with the shape of cross section of central through hole 3.
The concrete course of work is as follows:
1) material sample is circulated in the sample hose, puts into several steel mill balls in the sample hose, again sample hose is sealed with lid;
2) sample hose that all is poured into material sample is inserted into respectively in the sample box, and sample box was immersed in the liquid nitrogen cooling 1 minute 15 seconds, then sample box is fixed in the process box 1 of muller;
3) start muller, process box is under the effect of driving mechanism, slide bar is made the vertical direction double vibrations along the sample box that sliding guide mechanism central through hole 3 drives in the process box 1, under high-frequency vibration, mill ball impacts sample at a high speed and finishes grinding to sample, friction bump between ball and the ball can effectively cause the fragmentation of sample tissue or cell, and the crank mechanism reciprocal time is 300 a times/per minute, and thermostatic control is at 25 degree in the muller.
Claims (6)
1. high-flux tissue grinder, comprise pedestal, at least one process box and be used to drive the driving mechanism of process box, described process box is connected by crank mechanism with described driving mechanism, it is characterized in that: described crank mechanism is provided with sliding guide mechanism, described sliding guide mechanism comprises the slide-and-guide piece, described slide-and-guide piece is provided with central through hole, the periphery of described central through hole is provided with at least three rolling grooves, be provided with at least one rolling bearing in the described rolling groove, described rolling bearing radially parallel with the direction of described central through hole.
2. a kind of high-flux tissue grinder according to claim 1 is characterized in that: described slide-and-guide piece is provided with pin-and-hole, and the direction of described pin-and-hole is vertical with the direction of described central through hole.
3. a kind of high-flux tissue grinder according to claim 1, it is characterized in that: described crank mechanism comprises connecting rod and slide bar, described driving mechanism comprises pair Flywheel disc that goes out spindle motor and two equals in quality, described Flywheel disc is arranged on described pair and goes out on the output shaft of spindle motor both sides, described Flywheel disc is provided with excentric shaft, described excentric shaft is fixedlyed connected with described connecting rod one end, the described connecting rod other end is connected by being coupling with described slide bar, and described slide bar passes described central through hole and is connected with described process box.
4. a kind of high-flux tissue grinder according to claim 3, it is characterized in that: described output shaft end is provided with first groove, described Flywheel disc center pit is provided with second groove, and described first groove and described second groove closely cooperate by key.
5. a kind of high-flux tissue grinder according to claim 3 is characterized in that: the shape of cross section of described slide bar and described central through hole is square, is provided with four rolling grooves around the described central through hole.
6. a kind of high-flux tissue grinder according to claim 1, it is characterized in that: substrate and outer substrate in described pedestal comprises reach described outer base lower surface between base lower surface and the described outer upper surface of base plate around the upper surface of base plate, in described in described and are provided with soft core pad all around.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101641264A CN101852695B (en) | 2010-04-30 | 2010-04-30 | High-flux tissue grinder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101641264A CN101852695B (en) | 2010-04-30 | 2010-04-30 | High-flux tissue grinder |
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| Publication Number | Publication Date |
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| CN101852695A CN101852695A (en) | 2010-10-06 |
| CN101852695B true CN101852695B (en) | 2011-11-30 |
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| CN2010101641264A Active CN101852695B (en) | 2010-04-30 | 2010-04-30 | High-flux tissue grinder |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102288462B (en) * | 2011-01-25 | 2012-07-18 | 北京托摩根生物科技有限公司 | High-throughput tissue grinder |
| CN102901661B (en) * | 2012-10-16 | 2014-07-02 | 西北农林科技大学 | Soil grinding and screening device |
| CN104454777A (en) * | 2014-11-28 | 2015-03-25 | 天津市福臻机电工程有限公司 | Precise positioning locking device |
| CN106318849B (en) * | 2016-10-26 | 2018-07-03 | 锦州医科大学 | A kind of Cell vibration meter |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4505433A (en) * | 1982-09-28 | 1985-03-19 | Selenke William M | Tissue grinding and transporting device |
| DE29615162U1 (en) * | 1996-08-30 | 1996-10-31 | Heidolph Elektro Gmbh & Co Kg | Device for crushing cell tissue or organic substances using a test tube shaker |
| US5829696A (en) * | 1997-08-27 | 1998-11-03 | Michelle S. DeStefano | Sealed grinding and homogenizing apparatus |
| JP2004101297A (en) * | 2002-09-06 | 2004-04-02 | Toyobo Co Ltd | Sample crushing tool |
| CN201257396Y (en) * | 2008-07-29 | 2009-06-17 | 邸宏 | Simple plant material grinding device |
| CN101650274A (en) * | 2009-08-31 | 2010-02-17 | 宁波新芝生物科技股份有限公司 | High pass tissue grinder and grinding method |
| CN101653740A (en) * | 2009-09-04 | 2010-02-24 | 宁波新芝生物科技股份有限公司 | Sterile grinder |
-
2010
- 2010-04-30 CN CN2010101641264A patent/CN101852695B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4505433A (en) * | 1982-09-28 | 1985-03-19 | Selenke William M | Tissue grinding and transporting device |
| DE29615162U1 (en) * | 1996-08-30 | 1996-10-31 | Heidolph Elektro Gmbh & Co Kg | Device for crushing cell tissue or organic substances using a test tube shaker |
| US5829696A (en) * | 1997-08-27 | 1998-11-03 | Michelle S. DeStefano | Sealed grinding and homogenizing apparatus |
| JP2004101297A (en) * | 2002-09-06 | 2004-04-02 | Toyobo Co Ltd | Sample crushing tool |
| CN201257396Y (en) * | 2008-07-29 | 2009-06-17 | 邸宏 | Simple plant material grinding device |
| CN101650274A (en) * | 2009-08-31 | 2010-02-17 | 宁波新芝生物科技股份有限公司 | High pass tissue grinder and grinding method |
| CN101653740A (en) * | 2009-09-04 | 2010-02-24 | 宁波新芝生物科技股份有限公司 | Sterile grinder |
Non-Patent Citations (1)
| Title |
|---|
| 栾兴和等.平面连杆机构.《机械设计基础》.东北林业大学出版社,2007,111-112. * |
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| CN101852695A (en) | 2010-10-06 |
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