CN101849604B

CN101849604B - Production method for selenium-containing collagen

Info

Publication number: CN101849604B
Application number: CN2010101589960A
Authority: CN
Inventors: 袁抗美; 陈敦厚
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-04-27
Filing date: 2010-04-27
Publication date: 2012-04-18
Anticipated expiration: 2030-04-27
Also published as: CN101849604A

Abstract

The invention relates to a production method for selenium-containing collagen. The method adopts bones to make soup, turtles and chicken are contained in one pig stomach, pig skins and cow skins are contained in another pig stomach, the processed pig stomachs and fish are put together into a casserole filled with bone soup, and repetitive boiling, filtration, concentration, air drying, crushing and packaging are conducted to obtain the collagen product. The production technology of the invention is simple and unique, the expensive instruments and equipment are not required, the production period is short, the cost is very low, the produced product not only has the advantages and the application values of domestic and foreign similar products but also contains organic selenium, the content of the organic selenium reaches 6.1mg/kg high and cannot be found in the existing literature, the collagen is a special collagen product, the application value and the development and popularization value of the collagen are very high, especially the selenium has great function on cancer fighting and thereby the development prospect is very high.

Description

A kind of manufacturing approach that contains the collagen of selenium

Technical field:

The present invention relates to the manufacturing technology neck of collagen

Background technology:

What collagen was different with general protein is: collagen is triple-helix structure, and protein is double-spiral structure, and therefore, collagen is a kind of of protein, is a kind of special protein.

Along with science and technology and economic constantly advancing; People have carried out deep research to collagen; The discovery collagen has been widely used, and as in medicine, organizational project and food industry and cosmetics or the like industry, very high applied value is arranged; Therefore, numerous scientific and technical personnel's further investigation both domestic and external and Development and Production collagen.At present, the collagen production method is had two kinds both at home and abroad, a kind of is chemical method with solvent, and it dissolves neat difference according to used, can be divided into neutral sulfity process and acid process; Another kind is the biochemical process with enzyme.The technology of producing collagen with these methods is very complicated, as wanting broken biological tissue, also will separate with centrifuge, and tear the method deposition open with salt; Make range protein separately with chromatography or electrophoresis, also will let its crystallization at last, process dry powder.From above-mentioned production routine, production long in time limit also needs expensive instrument and equipment.Therefore, production cost is just very high, and the market price of its product is also quite high.At present, the international market price of collagen is about 5000 yuan/gram, and the cost of material valency of the collagen that domestic manufacturer produces is all at 495 yuan/gram.

Summary of the invention:

It is simple to the purpose of this invention is to provide a kind of technology, do not need expensive equipment, and production method is special, and production cost is extremely low again, and the manufacturing approach of the collagen of the product quality special again (containing selenium) of producing, and promptly is the object of the invention.

Fig. 1: be to make the collagen schematic flow sheet

In conjunction with accompanying drawing, detailed process of the present invention is described:

The present invention is made up of raw material, processing, packaging process:

One, raw material and consumption:

1, small water turtle is about one 1 kilogram

2, pig stomach (belly) is about two each 2 kilograms

3, each 2 kilograms of left and right sides ear of maize bone of pig bone and ox bone

4, pigskin and ox-hide are each about 2 kilograms

5, black chicken meat is about 1 kilogram

6, fish is about 1 kilogram

Two, processing:

1, pig bone and ox bone are cleaned respectively put into cauldron after smashing, after adding 40 kilograms in water and boiling, when temperature remains on 80 ℃; Boiled 2 hours, and when temperature is reduced to 60 ℃, boiled again 8 hours; Boiled when cooling the temperature to 40 ℃ more thereafter 4 hours, and at last bone was leached, pour into the bone soup of enduring in the marmite subsequent use;

2, with tortoise smash with black chicken meat with being placed in the pig stomach (belly), closely close with linear slit;

3, pigskin and ox-hide are put into another pig stomach (belly), closely close with linear slit;

4, pig stomach of handling well and fish are put into bone soup simultaneously, heat endure out after, temperature remains on 80 ℃; Boiled 2 hours, and when cooling the temperature to 60 ℃ then, stewed 8 hours again; At this moment, prick 20 eyelets on the pig Weishang, boiled 4 hours with identical temperature again with draw point; Thereafter simmered again after cooling the temperature to 40 ℃ 4 hours, then cooling.

5, pig stomach, fish pomace are taken out and filter;

6, filtered fluid is concentrated;

7, air-dry machine is air-dry, lets it become crystalline solid;

8, crystal is pulverized after, package encapsulation, the product of collagen.

Embodiment 1

One, raw material and consumption:

1, it is heavy about 1 kilogram to get 1 of small water turtle, puts into blue or green basin with rape oil earlier, then tortoise is put into the basin stomach and supports 3 days, smashes subsequent use;

2, get 2 in pig stomach (pork tripe), each is heavy about 2 kilograms, cleans subsequent use;

3, get ox-hide, each 2 kilograms of pigskins;

4, get each 2 kilograms of pig bone, ox bones (ear of maize bone), smash subsequent use;

5, heavy about 1 kilogram in the black-bone chicken, clean, shred subsequent use;

6, get about 1 kilogram of crucian, it is subsequent use to go internal organ to clean.

Two, processing

1, put into cauldron after pig bone and ox bone are smashed, add that 40 kg of water are boiled after, temperature remains on 80 ℃ and boiled 2 hours, when being cooled to 60 ℃, boils 8 hours again, and then when being cooled to 40 ℃, boils 4 for a short time, filters at last, leaches the bone slag, sliding soup is subsequent use;

2, small water turtle and black chicken meat are placed in the pig stomach together, tight with linear slit;

3, pigskin and ox-hide are placed in another pig stomach, tight with linear slit simultaneously;

4, two pig stomaches will handling well and fish put into the marmite that bone soup is housed heat endure out after, temperature remains on 80 ℃, boils 2 hours; When reducing to 60 ℃ to temperature, boiled again 8 hours, at this moment; Prick 20 eyelets with draw point on the pig Weishang, boiled 4 hours with identical temperature again, cool the temperature to 40 ℃ thereafter after; Simmered again 4 hours, then cold filtration.Concentrate at last, air-dry machine is air-dry, becomes crystalline solid, and crystalline solid is pulverized, pack, the collagen product.

Advantage of the present invention is:

1, production technology of the present invention is simple, unique, and the chemical method of its used solvent inside and outside need not be now is promptly without neutral sulfity process and acid process; It also is different from the biochemical process of now used enzyme; Instrument and equipment that more need not be expensive, and with short production cycle, production cost be the end very end very; The cost of material of every gram is produced valency less than 10 yuan, is that a kind of novel collagen product has develop and spread value very much;

2, the collagen of producing with the present invention, existing some, this product is through detecting; Finding not to the utmost has a certain amount of beneficial element, and what make more that the people is happy is to contain a certain amount of selenium element in this product, and the selenium constituent content is also very high; Up to 6.1mg/kg, the content of high like this selenium can not find out at the document aspect the existing collagen; In other all document of the world, also can not find out the content of such element.And what benefit selenium has to the mankind on earth: through a large amount of research with facts have proved that it is big that selenium is contributed meaning to the mankind, below we with some selenium and human relevant material are provided:

A, annex 1: the material of " selenium of dominating biological element ", this material proof selenium has very strong antitumaous effect and other effect;

B, annex 2: this part material proof selenium is playing critical effect aspect the treatment diabetes;

C, annex 3: this part material reference lacks the generation that selenium will cause various illnesss.

3, in the collagen with the present invention's production, contain the expensive element of such guarantor, the quality of this product is considerably beyond the quality of existing collagen product certainly, and its price lattice will be higher than market price both domestic and external certainly.

4, with regard to the advantage of collagen itself, it is having aspect medical material and the clinical practice: be used for operation suture thread, make stanch fibre, styptic sponge, dextran, make dressing, make artificial skin or the like; The beauty treatment and health care aspect: as anti-ageing, the fat-reducing or the like; Make various emulsifying agents and other food in aspect food; , in industrial aspect, all have been widely used at it like papermaking, process hides surfactant or the like aspect.

5, the product of the collagen that contains selenium of the present invention's production is a unique last word in the world today, and it has very high exploitation value and applied value.

Claims

1. manufacturing approach that contains the collagen of selenium is characterized in that: be made up of raw material and consumption and processing, packaging process:

1), raw material and consumption:

A, 1 of small water turtle are heavy 1 kilogram, and tortoise is put into to drip has the blue or green basin of rape oil to feed 3 days, smashes subsequent use then;

2 each 2 kilograms in B, pig stomach are cleaned subsequent use;

Each 2 kilograms of C, pig bone and ox bones are smashed subsequent use;

Each 2 kilograms on D, pigskin and ox-hide;

E, black chicken meat weigh 1 kilogram and clean, and shred subsequent use;

F, crucian weigh 1 kilogram and remove internal organ, and be subsequent use;

2), processing

A, put into cauldron after pig bone and ox bone smashed, add after 40 kg of water boil, boiled when temperature remains on 80 ℃ 2 hours, boiled when being cooled to 60 ℃ 8 hours again, and then boiled 4 hours when being cooled to 40 ℃, filter at last, bone soup is subsequent use;

B, with small water turtle and black chicken meat with being placed in the pig stomach, tight with suturing with thread management;

C, with pigskin and ox-hide with being placed in another pig stomach, tight with suturing with thread management;

D, two pig stomaches will handling well and fish are put into the marmite that bone soup is housed, heat endure out after, boiled when temperature is remained on 80 ℃ 2 hours; Boiled again when reducing to 60 ℃ to temperature 8 hours, and at this moment, pricked 20 eyelets on the pig Weishang with draw point; Boiled 4 hours with identical temperature again; Thereafter simmered again after cooling the temperature to 40 ℃ 4 hours, and cooled off then, filter, concentrate the air-dry one-tenth crystalline solid of air-dry machine at last;

3), packing:

Crystalline solid is pulverized, is packed, the collagen product.