CN101843871B - Chinese medicament for treating diabetic acro-necrosis - Google Patents
Chinese medicament for treating diabetic acro-necrosis Download PDFInfo
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- CN101843871B CN101843871B CN2009102421555A CN200910242155A CN101843871B CN 101843871 B CN101843871 B CN 101843871B CN 2009102421555 A CN2009102421555 A CN 2009102421555A CN 200910242155 A CN200910242155 A CN 200910242155A CN 101843871 B CN101843871 B CN 101843871B
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Abstract
一种治疗糖尿病肢端坏死的中药,属治疗外科病的中药领域;其目的是效果好、见效快;本发明采用黄柏、生地、薏苡仁、当归、茵陈、三七、连翘、灵芝等原料制成;它具有扶正培本,益气养血,活血化瘀,清热利湿,消肿散结的作用,具有效果显著,药效确切,见效较快的优点。This invention relates to a traditional Chinese medicine for treating diabetic necrosis of the extremities, belonging to the field of traditional Chinese medicine for treating surgical diseases. Its aim is to achieve good and rapid effects. The invention is made from raw materials such as Phellodendron bark, Rehmannia root, Coix seed, Angelica sinensis, Artemisia capillaris, Panax notoginseng, Forsythia, and Ganoderma lucidum. It has the effects of strengthening the body's resistance, replenishing qi and blood, promoting blood circulation and removing blood stasis, clearing heat and dampness, and reducing swelling and dissipating nodules. It has the advantages of significant effects, definite efficacy, and rapid onset of action.
Description
技术领域technical field
本发明属于治疗外科病的中药领域。The invention belongs to the field of traditional Chinese medicine for treating surgical diseases.
背景技术Background technique
目前用于治疗糖尿病肢端坏死的西药和中药,存在一些明显的不足:一是效果不明显,二是见效较迟缓,大量患者面对糖尿病肢端坏死束手无策,患肢久治不愈,不断恶化,最后不得不做截肢手术处理。The western and traditional Chinese medicines currently used to treat diabetic extremity necrosis have some obvious deficiencies: first, the effect is not obvious; Amputation was not performed.
针对以上提出的问题,本发明提供一种治疗糖尿病肢端坏死的中药,它能解决以往此类中药治疗中效果不够明显,见效比较迟缓的问题,效果好、见效快,具有效果显著,药效确切,见效较快的优点。In view of the problems raised above, the present invention provides a traditional Chinese medicine for the treatment of diabetic extremity necrosis, which can solve the problem that the effect of this type of traditional Chinese medicine is not obvious enough in the past, and the effect is relatively slow. Exactly, the advantage of quicker effect.
发明内容Contents of the invention
本发明是通过以下技术方案来实现的:The present invention is achieved through the following technical solutions:
1、一种治疗糖尿病肢端坏死的中药,采用中药原料制备,配方为(按重量比):1, a kind of Chinese medicine for the treatment of diabetic extremity necrosis, adopts Chinese medicine raw material to prepare, and formula is (by weight):
黄柏4——30份 生地5——40份 薏苡仁5——40份Phellodendron 4——30 parts Habitat 5——40 parts Coix seed 5——40 parts
当归4——30份 茵陈5——40份 三七3——20份Angelica 4——30 parts Yin Chen 5——40 parts Sanqi 3——20 parts
连翘4——30份 灵芝2——12份Forsythia 4-30 parts Ganoderma lucidum 2-12 parts
这种治疗糖尿病肢端坏死的中药是由下列方法制成的:This traditional Chinese medicine for treating diabetic extremity necrosis is made by the following methods:
(1)按上述重量比,将黄柏、生地、薏苡仁、当归、茵陈、连翘常规水提取工艺提取,制成浸膏细粉;(1) According to the above weight ratio, extract Phellodendron Phellodendron, Rehmannia Root, Coix Seed, Angelica, Capillary, and Forsythia with conventional water extraction process to make extract powder;
(2)按上述重量比,将三七、灵芝分别研成细粉,与上述浸膏细粉混合,搅拌均匀;根据需要,可制成中药冲剂、颗粒剂、散剂、胶囊剂、水丸剂、片剂等剂型。(2) According to the above weight ratio, grind Panax notoginseng and Ganoderma lucidum into fine powder respectively, mix with the above-mentioned extract powder, and stir evenly; as required, it can be made into Chinese medicine granules, granules, powders, capsules, water pills, Dosage forms such as tablets.
本发明是根据民间传统配方,根据中医扶正培本、活血化瘀的理论,精心研制而成。方中灵芝、生地扶正培本,益气养血,补益五脏,增强机体免疫力;当归、三七补血养血,活血化瘀;茵陈、薏苡仁清热利湿,行血消肿;佐以连翘、黄柏清热解毒,消肿散结。诸药配伍,相得益彰,共奏扶正培本,益气养血,活血化瘀,清热利湿,消肿散结之功,效果好,见效快,具有效果显著,药效确切,见效较快的优点。The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. In the prescription, Ganoderma lucidum and Shengdi Fuzheng Peiben can nourish qi and blood, nourish the five internal organs, and enhance the body's immunity; Forsythia and Cortex Phellodendri clear away heat and detoxify, reduce swelling and dissipate stagnation. All the medicines are compatible and complement each other. They play the role of strengthening the body, nourishing qi and nourishing blood, promoting blood circulation and removing blood stasis, clearing away heat and dampness, reducing swelling and dispelling stagnation. The effect is good and quick. advantage.
具体实施方式Detailed ways
通过以下实施方式对本发明做具体说明:The present invention is specifically described by the following embodiments:
1、取以下配方(重量按克为单位):1. Take the following formula (weight is in grams):
黄柏80克 生地100克 薏苡仁100克Phellodendron 80g Habitat 100g Coix Seed 100g
当归80克 茵陈100克 三七60克Angelica 80g Capillary 100g Panax notoginseng 60g
连翘80克 灵芝40克Forsythia 80g Ganoderma lucidum 40g
按规定重量,用常规水提取工艺将黄柏、生地、薏苡仁、当归、茵陈、连翘提取,制成浸膏细粉162克,将三七、灵芝分别研成细粉,与上述浸膏细粉混合,搅拌均匀,制成细小颗粒,装入0号胶囊,制成中药胶囊935粒,每粒胶囊内含中药细粉及提取物0.28克。According to the specified weight, use the conventional water extraction process to extract Cortex Phellodendron, Rehmannia, Coix Seed, Angelica, Yin Chen, and Forsythia to make 162 grams of extract powder, grind Sanqi and Ganoderma lucidum into fine powder, and mix with the above extract The fine powder is mixed, stirred evenly, made into fine particles, packed into No. 0 capsules, and made into 935 Chinese medicine capsules, each capsule containing 0.28 grams of Chinese medicine fine powder and extract.
2、取以下配方(重量按克为单位):2. Take the following formula (weight is in grams):
黄柏160克 生地200克 薏苡仁200克Phellodendron 160g Habitat 200g Coix seed 200g
当归160克 茵陈200克 三七90克160 grams of angelica, 200 grams of capillary, 90 grams of notoginseng
连翘160克 灵芝60克Forsythia 160g Ganoderma lucidum 60g
按上述同样的方法,制成中药胶囊1692粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 1692 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.
3、取以下配方(重量按克为单位):3. Take the following formula (the weight is in grams):
黄柏300克 生地400克 薏苡仁400克Phellodendron 300g Habitat 400g Coix Seed 400g
当归300克 茵陈400克 三七200克Angelica 300g Capillary 400g Sanqi 200g
连翘300克 灵芝120克Forsythia 300g Ganoderma lucidum 120g
按上述同样的方法,制成中药胶囊3392粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 3392 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.
4、取以下配方(按重量比):4. Take the following formula (by weight):
黄柏7份 生地9份 薏苡仁9份7 parts of Phellodendron 9 parts of Habitat 9 parts of Coix Seed
当归7份 茵陈9份 三七4份7 parts of Angelica, 9 parts of Yinchen, 4 parts of Panax notoginseng
连翘7份 灵芝3份Forsythia 7 parts Ganoderma lucidum 3 parts
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.
5、取以下配方(按重量比):5. Take the following formula (by weight):
黄柏20份 生地30份 薏苡仁30份20 parts of Cortex Phellodendri 30 parts of Habitat 30 parts of Coix Seed
当归20份 茵陈30份 三七12份20 parts of Angelica, 30 parts of Yinchen, 12 parts of Panax notoginseng
连翘20份 灵芝8份Forsythia 20 parts Ganoderma lucidum 8 parts
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.
临床资料:clinical information:
本发明以中医糖尿病肢端坏死为例,经7例临床观察。选择中医诊断糖尿病肢端坏死为标准:糖尿病患者形体消瘦,肢软乏力;患肢发凉,血液循环不畅;肌肉萎缩;下肢脉搏微弱,间歇性跛行;腿脚皮肤发红、发黑、发紫,组织坏死;肢体麻木,患肢肢端疼痛;患肢肢端溃疡、溃烂,流血流脓,久不愈合。如上症状,即可确诊。在确诊观察的对象中,男性4例,女性3例,无其它严重疾病,年龄为47岁-78岁,平均年龄65岁。The present invention takes diabetic extremity necrosis in traditional Chinese medicine as an example, through clinical observation of 7 cases. TCM diagnosis of diabetic extremity necrosis was selected as the standard: diabetic patients are thin and weak, with weak limbs; cold limbs, poor blood circulation; muscle atrophy; weak pulse of lower limbs, intermittent claudication; redness, blackness, and purple skin of legs and feet , tissue necrosis; limb numbness, pain in the extremity of the affected extremity; ulceration, ulceration, bleeding and pus in the extremity of the affected extremity, which will not heal for a long time. The above symptoms can be diagnosed. Among the confirmed observation objects, there were 4 males and 3 females, without other serious diseases, aged from 47 to 78 years old, with an average age of 65 years old.
疗效判定:Judgment of curative effect:
1、显效:体质增强,身上有劲;肢体温暖,发凉消失;皮肤颜色由黑紫逐步变白(正常皮肤颜色),血液循环明显改善;患肢麻木、肢端疼痛明显减轻;肢端溃烂缓解、愈合。1. Significant effect: Physical fitness is enhanced, body is strong; limbs are warm, and coldness disappears; skin color gradually turns from black to white (normal skin color), blood circulation is significantly improved; numbness of affected limbs, pain in extremities are significantly relieved; extremity ulceration is relieved ,heal.
2、有效:体质增强,身上有劲,肢体温暖,血液循环改善;肢体麻木、疼痛有所缓解。2. Effective: Physical fitness is enhanced, body is strong, limbs are warm, blood circulation is improved; limb numbness and pain are relieved.
3、无效:病症无变化。3. Ineffective: no change in symptoms.
临床实验时,除降糖药物以外,停服其它药物和保健营养品。服用本发明中药胶囊,观察6个月,为一个疗程。服用方法:每日2次,每次4粒胶囊,每粒胶囊内含中药细粉及提取物0.28克,饭后温开水送服,1个月后症状即有缓解,服用6个月后,症状明显改善。临床实验的7人中,显效3人,有效3人,无效1人,总有效率85.7%。During clinical trials, except for hypoglycemic drugs, stop taking other drugs and health nutrition products. Take Chinese medicine capsule of the present invention, observe 6 months, be a course of treatment. Dosing method: 2 times a day, 4 capsules each time, each capsule contains 0.28 grams of fine powder and extract of traditional Chinese medicine, take it with warm water after meals, the symptoms will be relieved after 1 month, and after 6 months of taking, Symptoms improved significantly. Among the 7 people in the clinical trial, 3 people were markedly effective, 3 people were effective, and 1 person was ineffective, and the total effective rate was 85.7%.
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| CN2009102421555A CN101843871B (en) | 2009-12-09 | 2009-12-09 | Chinese medicament for treating diabetic acro-necrosis |
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| CN2009102421555A CN101843871B (en) | 2009-12-09 | 2009-12-09 | Chinese medicament for treating diabetic acro-necrosis |
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| CN101843871A CN101843871A (en) | 2010-09-29 |
| CN101843871B true CN101843871B (en) | 2011-08-10 |
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Non-Patent Citations (1)
| Title |
|---|
| 白岩.中药内服外敷治疗糖尿病足肢端坏死39例.《实用中医内科杂志》.2007,第21卷(第4期),第83页. * |
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