CN101836892A - Method for regulating and controlling working parameters of radio-frequency ablation instrument in real time - Google Patents
Method for regulating and controlling working parameters of radio-frequency ablation instrument in real time Download PDFInfo
- Publication number
- CN101836892A CN101836892A CN201010164221A CN201010164221A CN101836892A CN 101836892 A CN101836892 A CN 101836892A CN 201010164221 A CN201010164221 A CN 201010164221A CN 201010164221 A CN201010164221 A CN 201010164221A CN 101836892 A CN101836892 A CN 101836892A
- Authority
- CN
- China
- Prior art keywords
- damage
- time
- radio
- temperature
- frequency ablation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000007674 radiofrequency ablation Methods 0.000 title claims abstract description 46
- 238000000034 method Methods 0.000 title claims abstract description 34
- 230000001276 controlling effect Effects 0.000 title abstract 2
- 230000001105 regulatory effect Effects 0.000 title abstract 2
- 230000003287 optical effect Effects 0.000 claims abstract description 9
- 230000008569 process Effects 0.000 claims abstract description 7
- 238000012544 monitoring process Methods 0.000 claims description 19
- 238000013178 mathematical model Methods 0.000 claims description 16
- 238000012216 screening Methods 0.000 claims description 6
- 238000005481 NMR spectroscopy Methods 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 2
- 238000003672 processing method Methods 0.000 claims description 2
- 238000002329 infrared spectrum Methods 0.000 abstract description 6
- 201000004569 Blindness Diseases 0.000 abstract description 2
- 238000002679 ablation Methods 0.000 abstract 9
- 230000014509 gene expression Effects 0.000 abstract 5
- 230000001360 synchronised effect Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 description 11
- 230000000694 effects Effects 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 6
- 230000008859 change Effects 0.000 description 5
- 108010054147 Hemoglobins Proteins 0.000 description 3
- 102000001554 Hemoglobins Human genes 0.000 description 3
- 230000009102 absorption Effects 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 239000013307 optical fiber Substances 0.000 description 3
- 238000004497 NIR spectroscopy Methods 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000001320 near-infrared absorption spectroscopy Methods 0.000 description 2
- 230000008520 organization Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 102000018832 Cytochromes Human genes 0.000 description 1
- 108010052832 Cytochromes Proteins 0.000 description 1
- 208000032612 Glial tumor Diseases 0.000 description 1
- 206010018338 Glioma Diseases 0.000 description 1
- 206010019695 Hepatic neoplasm Diseases 0.000 description 1
- 108010064719 Oxyhemoglobins Proteins 0.000 description 1
- 208000018737 Parkinson disease Diseases 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000002309 gasification Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000024278 histolysis Effects 0.000 description 1
- 208000014018 liver neoplasm Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 208000023958 prostate neoplasm Diseases 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Images
Landscapes
- Surgical Instruments (AREA)
Abstract
The invention discloses a method for regulating and controlling working parameters of a radio-frequency ablation instrument in real time, which belongs to the technical field of near infrared spectrum data processing. The method comprises the following steps of: acquiring n groups of corresponding values of ablation temperature T and ablation time t according to the radio-frequency ablation instrument, meanwhile obtaining n groups of reduced scattering coefficients mu's synchronous with the corresponding values through real-time acquisition of an optical parameter measuring system, obtaining a relational expression mu's = f1 (T, t), and then obtaining a relational expression V = f2 (T, t) of an ablation volume V, the ablation temperature T and the ablation time t through synchronously acquired data of the ablation volume V; obtaining a relational expression V = g (mu's) of the reduced scattering coefficients mu's and the ablation volume V through the previous two relational expressions; setting a corresponding expected reduced scattering coefficient mu'sth according to an expected ablation volume V0 through the relational expression V = g (mu's); when the mu's is equal to the mu'sth, finishing a radio-frequency ablation process; and when the mu's is less than the mu'sth, adjusting the parameters of the radio-frequency ablation instrument according to a curve state of the mu's. Therefore, the method solves the problems that the conventional radio-frequency ablation instrument has high ablation blindness and low precision.
Description
Technical field
The present invention relates to a kind of method of running parameter real-time monitoring of radio-frequency ablation instrument, the reduced scattering coefficient μ ' that especially utilizes near-infrared spectrum technique to collect
sThe running parameter of radio-frequency ablation instrument is carried out the method for real-time monitoring.
Background technology
Radio frequency (Radio frequency is that a kind of frequency is the electromagnetic wave of 50kHz～2000kHz RF), its electric current high concentration, and with high frequency generation ion vibration friction, thereby in tissue, produce heat, make histolysis, gasification.It is comparatively satisfied for the damage effect of current parkinson disease, all kinds of tumor (constitutional liver tumor, breast tumor, cerebral glioma, prostate tumor etc.) to damage art.Damage degree and target spot positioning accuracy, damage that kitchen range size, heat are coagulated temperature, to burn factor such as choosing of time and stimulus parameter closely related, present domestic clinicist is to pass through previous experience at choosing of the damage parameter of damaging the kitchen range size (damage temperature T and damage time t), damage effect in the art also is that the reflection of seeing patient is estimated, lack monitoring in real time and damage degree methods, this has caused the situation of the not high and many recurrences of surgical healing rate.
The method for supervising of damaging degree in the more satisfactory clinically radio-frequency ablation art mainly is to navigate in MRI real-time navigation and the ultrasonic art in the art.The distribute monitoring of the degree of damaging of the temperature field that MRI utilize to damage target spot in the art, can draw the damage volume, estimate and damage effect, obtain generally approval both domestic and external, but there are several important problem: 1, MRI equipment price costliness in the art, consider the yet necessary special design and fabrication of environment for use radio-frequency ablation equipment, the radio-frequency ablation operation in the most hospitals of China does not at present have this condition.What 2, MRI monitored in real time in the art is temperature, distribute by the temperature field and to estimate to damage effect, the damage time of different temperature points, it organizes monitoring parameter (as: damaging the tissue coagulation degree of target area etc.) in real time according to still lacking, the real-time quantitative that just lacks the damage degree is described, and the temperature field distributes and is not equal to damage degree model in other words.
(Near Infrared Spectroscopy, NIRS) Study on Technology occurs near infrared spectrum very early.1977, Jobsis on " Science " magazine reported first hemoglobin and cytochrome absorption characteristic in specific near infrared region, and find that HbO2 Oxyhemoglobin and reduced hemoglobin have two absworption peaks at 735nm and 850nm place respectively, its variation can reflect the oxygen carrier situation of hemoglobin.This report has caused extensive attention.After this, a lot of research groups are promoted this method from different separately angles and are come, and in different fields it have been carried out deep research.
At present, be widely used in the effect etc. of the transmission course monitoring of optical property, types of organization's identification, cancer diagnosis, medicine of postgraduate's fabric texture and organizational structure and composition Study, organization internal scattering particles size, density, near infrared absorption medicine in biomedical sector NIRS technology.Over nearly 10 years, along with the development of optical fibers and sensing technology, near-infrared spectrum technique has obtained using widely at medical domain.Because different tissues has different absorptions and scattering properties near infrared light in the organism, so near infrared light has stronger separating capacity to the variation of different tissues and tissue.According to this specific character, can utilize near infrared spectroscopy to measure some optical parametric (as the reduction scattering coefficient) of biological tissue, thereby carry out significant relatedly with some physiological parameter of tissue, set up the related mathematical model of optical parametric and these physiological parameters.
Summary of the invention
Goal of the invention:
The objective of the invention is to damage the low problem of blindness height, accuracy that exists in the therapeutic instrument real work, propose a kind of near-infrared spectrum technique that utilizes, the running parameter of radio-frequency ablation instrument is carried out the method for real-time monitoring at present radio frequency.
Technical scheme:
The present invention adopts following technical scheme for achieving the above object:
A kind of running parameter real-time monitoring method of radio-frequency ablation instrument may further comprise the steps:
Step 1, when adopting radio-frequency ablation instrument that objective body is damaged, corresponding damage temperature T of n group and damage time t are set respectively damage, adopt the collection of biological tissue optical parameter measuring system to damage temperature T and the corresponding real-time reduced scattering coefficient μ ' of damage time t simultaneously with every group
sDamage temperature T by gathering the said n group, damage time t and reduced scattering coefficient μ '
sReal-time corresponding data, set up reduced scattering coefficient μ '
sWith the mathematical model f that damages temperature T and damage time t
1:
μ′
s＝f
1(T，t) (1)
Wherein n is a natural number;
V＝f
2(T，t) (2)
V＝g(μ′
s) (3)
Step 4 before the formal image data of radio-frequency ablation instrument, obtains the volume V that objective body is damaged in expection by nuclear magnetic resonance image
0, according to mathematical model f
2Determine to damage temperature T and damage time t;
Step 5 is by the volume V of relationship (3) acquisition with expection damage objective body
0Corresponding expection reduced scattering coefficient μ '
Sth
Step 6 is utilized the biological tissue optical parameter measuring system in the radio-frequency ablation process, gather in real time to obtain reduced scattering coefficient μ '
sValue, as μ '
sValue reach desired value μ '
SthThe time, promptly control radio-frequency ablation instrument and finish to damage.
Further, in the step 1 of the running parameter real-time monitoring method of radio-frequency ablation instrument of the present invention, the step 2, the span of T is 50 ℃～100 ℃, and the span of t is 5s～120s.
Further, in the step 4 of the running parameter real-time monitoring method of radio-frequency ablation instrument of the present invention, damage the volume V of objective body when expection
0Known, and damage temperature T and damage time t when all unknown, definite concrete steps of damaging temperature T and damaging time t are:
Steps A, setting m group damage time t are according to mathematical model f
2, try to achieve the value that m organizes corresponding damage temperature T, draw the m group is damaged objective body about expection volume V
0The damage scheme, the T span is 50 ℃～100 ℃, the span of t is 5s～120s, m is a natural number;
Step B, the temperature that can be provided with according to radio-frequency ablation instrument, the minimum precision of time are screened the m group damage scheme of steps A, get rid of those and exceed the damage scheme that radio-frequency ablation instrument is provided with accuracy rating, draw effective damage scheme;
Step C carries out postsearch screening to effective damage scheme that step B obtains, and filtering out the same damage time, to damage down temperature minimum, the shortest scheme of damage time under the perhaps same damage temperature, with it as preferred option.
Further, in the step 6 of the running parameter real-time monitoring method of radio-frequency ablation instrument of the present invention, as μ '
s＜μ '
SthThe time, according to μ '
sThe situation of curve, take following two kinds of processing methods:
1., as μ '
sCurve when being in flat stage, i.e. the initial damage temperature T of setting
1Damaged t down,
1Behind the duration,, damage volume and all no longer increase μ ' no matter the damage time, what increased for another example
sCan not reach desired value μ '
Sth, should reset this moment and damage temperature is T
2, and T
2＞T
1, return step 4 again, adopt radio-frequency ablation instrument to reset and damage temperature T
2With damage time t
2After, proceed to damage, monitor μ ' simultaneously
sVariation tendency;
2., as μ '
sCurve when being in ascent stage, i.e. the initial damage temperature T of setting
1Damaged t down,
1Behind the duration, μ '
sAlso the value of reaching capacity is not damaged volume simultaneously and is not yet arrived desired value; If prolong the damage time, μ '
sStill will continue to rise, until reaching desired value μ '
SthSize, corresponding damage volume also can continue to increase, until infinitely near target volume V
0, should keep damaging temperature-resistant this moment, i.e. T
2=T
1, prolong damage time, i.e. t
2＞t
1, proceed to damage, until μ '
s=μ '
Sth
Beneficial effect:
1, real-time, accuracy is high.Experiment shows, the damage degree is promptly damaged the size and the μ ' of volume
sSituation of change closely related, so μ '
sReal-time monitor factor as the degree of damage has good effect.
2, cost is low.Method cost provided by the invention reduces greatly, and building of biological tissue optical parameter measuring system is convenient relatively, and it is also relatively easy to implement.
3, workable.The method that the present invention proposes can realize owing operation control and crossing operation control of radio-frequency ablation instrument, and is workable, safe.
Description of drawings
Fig. 1 is a flow chart of the present invention.
Fig. 2 is μ ' in the embodiments of the invention
sSituation of change.
The specific embodiment
Below in conjunction with accompanying drawing technical scheme of the present invention is elaborated:
Accompanying drawing 1 is a detail flowchart of the present invention.Before adopting radio-frequency ablation instrument to damage operation,, obtain target as nuclear magnetic resonance image and damage the long-pending big or small V of stove by other medical imaging means
0, according to mathematical model (2): V=f
2(T, t) setting damage temperature and damage time are respectively T
1, t
1When damaging beginning, utilize near infrared spectra collection systematic observation reduced scattering coefficient μ '
sVariation.If its size reaches desired value μ '
Sth, then can think to reach the damage purpose, can finish immediately to damage; If its size does not reach desired value μ '
Sth, then enter scheme correction link, step 5 in the visible specific embodiment of concrete situation analysis and amendment scheme.
As shown in Figure 2, be reduced scattering coefficient μ '
sSituation of change.Three curves the 1,2, the 3rd in the accompanying drawing 2, reduced scattering coefficient μ '
sThree kinds of situations of change, round dot is μ '
SthValue.The left side is the damage body generalized section that the radio-frequency ablation electrode forms at objective body among the figure, and D is the radio-frequency ablation electrode of built-in pair of optical fiber, and (volume was V to measurement gained focal zone before A, B, three zones of C were respectively art
0), actual damage zone that forms and the forward sight distance of damaging the electrode built-in fiber.
Below the present invention is described in detail.
Step 1, the location.Parameters such as the preceding center position coordinates according to relevant medical detection means acquisition radio-frequency ablation kitchen range of art, transverse diameter, vertical footpath size calculate the volume V that target is damaged kitchen range through ellipsoid volume computing formula
0, and utilize motor will damage eletrode tip to be positioned to the centre coordinate position.
As shown in table 1, work as V
0=25.5mm
3The time, table 1 has provided the screening process of scheme.Initial scheme be according to said method find the solution draw corresponding to damage time t be 5s, 10s, 15s, 20s ... each damages the value of temperature T during 120s, now be illustrated at a concrete radio-frequency ablation example, damaging Scheme Selection in the other kinds radio-frequency ablation art all can be with reference to this technology path.According to initial scheme 1, when the damage time that gives was 20s, desire was damaged V
0=25.5mm
3Volume, then should be provided with and damage temperature is 99.7 ℃; In like manner, according to initial scheme 3, when the damage time that gives was 30s, desire was damaged V
0=25.5mm
3Volume, then should be provided with and damage temperature is 86.2 ℃.The temperature T excursion is 50 ℃～100 ℃, damage time t excursion is 5s～120s, and the damage time when being 5s, 10s, 15s the damage temperature of correspondence all exceed 100 ℃ of maximum temperatures, therefore, the damage time is that the scheme of 5s, 10s, 15s does not satisfy condition in the initial scheme, does not provide.
Because temperature, time value must meet the temperature that radiofrequency generator can be provided with, the minimum precision of time, therefore, utilize related algorithm that 21 kinds of initial methods are once screened, draw 6 kinds of method for optimizing, this class scheme belongs to effective scheme, for Scheme Selection provides reference frame.
For not causing damage, preferred option is taked the value scheme of insurance relatively usually in this example, therefore can utilize algorithm that scheme is carried out postsearch screening.Postsearch screening is to filter out the same damage time from preferred version to damage down temperature minimum, the shortest scheme of damage time under the perhaps same damage temperature, with its a kind of as preferred option, as when the damage temperature is 70 ℃, relatively the damage scheme of insurance is the shortest one group of damage time, and promptly scheme 1,2,3,4 is exercisable preferred option.
Table 1 option screening process
Step 4, monitoring.According to T and the t that step 3 obtains, formulate first-selected damage scheme T
1, t
1(choose reasonable of damaging scheme is seen step 1) damages focal zone.When formally beginning to damage, record reduced scattering coefficient μ '
sSituation of change.
Step 5 is analyzed.The μ ' of real-time monitoring
sCurve is seen accompanying drawing 2, and round dot is μ '
SthValue, the left side damage kitchen range generalized section that be the radio-frequency ablation electrode form at objective body among the figure, D is the radio-frequency ablation electrode of built-in pair of optical fiber, (volume was V to measurement gained focal zone before A, B, three zones of C were respectively art
0), actual damage zone that forms and the forward sight distance of damaging the electrode built-in fiber.
According to technology path of the present invention, the μ ' that monitoring relatively in real time obtains
sWith the μ ' that calculates in the step 3
SthSize has two kinds of significant results: one, in preferred option, promptly damaging temperature is T
1, the damage time is t
1Situation under, μ '
s〉=μ '
Sth, see the curve 3 in the accompanying drawing 2, the μ ' of this moment
sReached desired value, illustrate damage zone that current damage forms just unlimited near or exceeded target and damaged the kitchen range size, continue to damage neural or other significant points in the then very possible tissue of burn again, should finish immediately to damage, this has realized the operation of crossing of damaging is controlled, in case this kind situation can be considered as reaching, then finish damage substantially; Its two, the damage temperature is T
1, the damage time reaches t
1The time, μ '
s＜μ '
Sth, illustrating that miss the mark damage kitchen range size is gone back in the damage zone of current damage formation this moment, still need continue to damage, realized the operation of owing of damaging process is controlled.
Now be elaborated: μ ' at the amendment scheme of owing to operate control
s＜μ '
SthThe time, reduced scattering coefficient μ ' is described
sDo not reach desired value, see the curve 1,2 in the accompanying drawing 2, wherein curve 1 is μ '
sSituation when being in flat stage shows the initial damage temperature T of setting this moment
1Damaged t down,
1Behind the duration, no matter the damage time, what increased for another example, the damage stove is long-pending all no longer to be increased, i.e. μ '
sCan not reach desired value μ '
SthAmendment scheme is targetedly: resetting the damage temperature according to preferred version is T
2, and T
2＞T
1, T
2Pairing damage time t
2By model t
2=f (T
2, V
o) draw.After setting parameter value, continue to damage, back μ ' is revised in observation
sVariation tendency.
Reduced scattering coefficient μ '
sDo not reach the another kind of situation of desired value such as the curve 2 in the accompanying drawing 2, at this moment μ '
sBe in ascent stage.The initial damage temperature T that this explanation is being set
1Damaged t down,
1Behind the duration, μ '
sThe value of reaching capacity not also.Damage volume does not in this case also reach the limit of, if prolong the damage time, μ '
sStill might rise, even reach desired value μ '
SthSize, the damage volume of its correspondence also might continue to increase, even infinitely near target volume V
0Amendment scheme is targetedly: keep damage temperature-resistant, i.e. T
2=T
1, prolong damage time, i.e. t
2＞t
1, until μ '
s=μ '
Sth
Claims (4)
1. the running parameter real-time monitoring method of a radio-frequency ablation instrument is characterized in that: may further comprise the steps:
Step 1, when adopting radio-frequency ablation instrument that objective body is damaged, corresponding damage temperature T of n group and damage time t are set respectively damage, adopt the collection of biological tissue optical parameter measuring system to damage temperature T and the corresponding real-time reduced scattering coefficient μ ' of damage time t simultaneously with every group
sDamage temperature T by gathering the said n group, damage time t and reduced scattering coefficient μ '
sReal-time corresponding data, set up reduced scattering coefficient μ '
sWith the mathematical model f that damages temperature T and damage time t
1:
μ′
s＝f
1(T，t) (1)
Wherein n is a natural number;
Step 2 in step 1, after the radio-frequency ablation end, is gathered objective body simultaneously and is damaged long-pending V of stove and the real-time corresponding data of damaging temperature T, damage time t, obtains objective body volume V that damages and the mathematical model f that damages temperature T, damage time t
2:
V＝f
2(T，t) (2)
Step 3 is according to mathematical model f
1With mathematical model f
2, draw reduced scattering coefficient μ '
sThe relationship (3) of the volume V that damages with objective body:
V＝g(μ′
s) (3)
Step 4 before the formal image data of radio-frequency ablation instrument, obtains the volume V that objective body is damaged in expection by nuclear magnetic resonance image
0, according to mathematical model f
2Determine to damage temperature T and damage time t;
Step 5 is by the volume V of relationship (3) acquisition with expection damage objective body
0Corresponding expection reduced scattering coefficient μ '
Sth
Step 6 is utilized the biological tissue optical parameter measuring system in the radio-frequency ablation process, gather in real time to obtain reduced scattering coefficient μ '
sValue, as μ '
sValue reach desired value μ '
SthThe time, promptly control radio-frequency ablation instrument and finish to damage.
2. the running parameter real-time monitoring method of radio-frequency ablation instrument according to claim 1, it is characterized in that: in described step 1, the step 2, the T span is 50 ℃～100 ℃, and the span of t is 5s～120s.
3. the running parameter real-time monitoring method of radio-frequency ablation instrument according to claim 1 is characterized in that: in the described step 4, damage the volume V of objective body when expection
0Known, and damage temperature T and damage time t when all unknown, definite concrete steps of damaging temperature T and damaging time t are:
Steps A, setting m group damage time t are according to mathematical model f
2, try to achieve the value that m organizes corresponding damage temperature T, draw the m group is damaged objective body about expection volume V
0The damage scheme, the T span is 50 ℃～100 ℃, the span of t is 5s～120s, m is a natural number;
Step B, the temperature that can be provided with according to radio-frequency ablation instrument, the minimum precision of time are screened the m group damage scheme of steps A, get rid of those and exceed the damage scheme that radio-frequency ablation instrument is provided with accuracy rating, draw effective damage scheme;
Step C carries out postsearch screening to effective damage scheme that step B obtains, and filtering out the same damage time, to damage down temperature minimum, the shortest scheme of damage time under the perhaps same damage temperature, with it as preferred option.
4. the running parameter real-time monitoring method of radio-frequency ablation instrument according to claim 1 is characterized in that: in step 6, as μ '
s＜μ '
SthThe time, according to μ '
sThe situation of curve, take following two kinds of processing methods:
1., as μ '
sCurve when being in flat stage, i.e. the initial damage temperature T of setting
1Damaged t down,
1Behind the duration,, damage volume and all no longer increase μ ' no matter the damage time, what increased for another example
sCan not reach desired value μ '
Sth, should reset this moment and damage temperature is T
2, and T
2＞T
1, return step 4 again, adopt radio-frequency ablation instrument to reset and damage temperature T
2With damage time t
2After, proceed to damage, monitor μ ' simultaneously
sVariation tendency;
2., as μ '
sCurve when being in ascent stage, i.e. the initial damage temperature T of setting
1Damaged t down,
1Behind the duration, μ '
sAlso the value of reaching capacity is not damaged volume simultaneously and is not yet arrived desired value; If prolong the damage time, μ '
sStill will continue to rise, until reaching desired value μ '
SthSize, corresponding damage volume also can continue to increase, until infinitely near target volume V
0, should keep damaging temperature-resistant this moment, i.e. T
2=T
1, prolong damage time, i.e. t
2＞t
1, proceed to damage, until μ '
s=μ '
Sth
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010164221A CN101836892A (en) | 2010-05-06 | 2010-05-06 | Method for regulating and controlling working parameters of radio-frequency ablation instrument in real time |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010164221A CN101836892A (en) | 2010-05-06 | 2010-05-06 | Method for regulating and controlling working parameters of radio-frequency ablation instrument in real time |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101836892A true CN101836892A (en) | 2010-09-22 |
Family
ID=42740739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201010164221A Pending CN101836892A (en) | 2010-05-06 | 2010-05-06 | Method for regulating and controlling working parameters of radio-frequency ablation instrument in real time |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101836892A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112603536A (en) * | 2020-12-29 | 2021-04-06 | 北京华科恒生医疗科技有限公司 | Method and system for generating electrode thermal coagulation parameters in three-dimensional model |
| CN113440250A (en) * | 2021-05-28 | 2021-09-28 | 南京航空航天大学 | Microwave ablation region defining method based on tissue reduced scattering coefficient |
-
2010
- 2010-05-06 CN CN201010164221A patent/CN101836892A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112603536A (en) * | 2020-12-29 | 2021-04-06 | 北京华科恒生医疗科技有限公司 | Method and system for generating electrode thermal coagulation parameters in three-dimensional model |
| CN113440250A (en) * | 2021-05-28 | 2021-09-28 | 南京航空航天大学 | Microwave ablation region defining method based on tissue reduced scattering coefficient |
| CN113440250B (en) * | 2021-05-28 | 2023-01-06 | 南京航空航天大学 | Microwave ablation area defining device based on tissue reduced scattering coefficient |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7871406B2 (en) | Methods for planning and performing thermal ablation | |
| US8155416B2 (en) | Methods and apparatuses for planning, performing, monitoring and assessing thermal ablation | |
| US8556888B2 (en) | Methods and apparatuses for performing and monitoring thermal ablation | |
| CN108471949B (en) | Reflective mode multispectral time-resolved optical imaging method and device for tissue classification | |
| JP6568478B2 (en) | Planning, guidance and simulation system and method for minimally invasive treatment | |
| US20080033417A1 (en) | Apparatus for planning and performing thermal ablation | |
| CA2694471C (en) | System and method for controlling and adjusting interstitial photodynamic light therapy parameters | |
| US20080033418A1 (en) | Methods for monitoring thermal ablation | |
| CN103458816B (en) | Functional-imaging-based ablation monitoring | |
| CN107582042A (en) | Multiple electro-anatomical maps automatically create | |
| CN107427280A (en) | For the system and method for the adaptive ablation and treatment that are monitored based on elastogram | |
| CN108478192B (en) | Measuring system for estimating skin tissue micro-vessel depth | |
| EP2068736A1 (en) | Methods and systems for planning, performing and monitoring thermal ablation | |
| CN102166135B (en) | High-intensity focused ultrasound treatment device | |
| US20210113094A1 (en) | Method and examination apparatus for medical examination of an animal | |
| CN106264485A (en) | Monitor system, temperature monitor and body temperature data processing equipment thereof | |
| Chen et al. | Tracking the in vivo spatio-temporal patterns of neovascularization via NIR-II fluorescence imaging | |
| CN101836892A (en) | Method for regulating and controlling working parameters of radio-frequency ablation instrument in real time | |
| CN105615998B (en) | A kind of atherosclerosis guiding target treatment device | |
| CN1806757A (en) | Three-dimensional imaging and intellectual treatment system for dermalvascular pathological change | |
| CN107693948B (en) | Monitoring method, device, Medical Devices and the storage medium of infrared treatment effect | |
| CN106667430A (en) | Nano-reinforced functional blood oxygen imaging diagnosing and treating system for breast tumor and application thereof | |
| CN101297761A (en) | Thermotherapy nondestructive temperature measuring equipment based on type-B ultrasonic image | |
| CN110917500A (en) | Diagnosis and treatment system for burned tissues | |
| CN204233210U (en) | Full frequency band combined type Wicresoft radio frequency pain therapeutic equipment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20100922 |