CN101829318B - Il-28和il-29治疗癌症和自身免疫性疾病的用途 - Google Patents
Il-28和il-29治疗癌症和自身免疫性疾病的用途 Download PDFInfo
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- CN101829318B CN101829318B CN2010101140769A CN201010114076A CN101829318B CN 101829318 B CN101829318 B CN 101829318B CN 2010101140769 A CN2010101140769 A CN 2010101140769A CN 201010114076 A CN201010114076 A CN 201010114076A CN 101829318 B CN101829318 B CN 101829318B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59206904P | 2004-07-29 | 2004-07-29 | |
| US60/592,069 | 2004-07-29 | ||
| US62970204P | 2004-11-19 | 2004-11-19 | |
| US60/629,702 | 2004-11-19 | ||
| US67604705P | 2005-04-29 | 2005-04-29 | |
| US60/676,047 | 2005-04-29 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200580030590 Division CN101031316A (zh) | 2004-07-29 | 2005-07-29 | Il-28和il-29治疗癌症和自身免疫性疾病的用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101829318A CN101829318A (zh) | 2010-09-15 |
| CN101829318B true CN101829318B (zh) | 2012-07-04 |
Family
ID=35786785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010101140769A Expired - Lifetime CN101829318B (zh) | 2004-07-29 | 2005-07-29 | Il-28和il-29治疗癌症和自身免疫性疾病的用途 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US7351689B2 (enExample) |
| EP (2) | EP1793845A2 (enExample) |
| JP (1) | JP2008508310A (enExample) |
| CN (1) | CN101829318B (enExample) |
| AU (1) | AU2005266892B2 (enExample) |
| BR (1) | BRPI0513865A (enExample) |
| CA (1) | CA2574564C (enExample) |
| IL (1) | IL180589A0 (enExample) |
| WO (1) | WO2006012644A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7038032B2 (en) | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
| US7910313B2 (en) | 2001-04-20 | 2011-03-22 | Zymogenetics, Inc. | Cytokine protein family |
| EP2251353B1 (en) * | 2003-08-07 | 2013-03-06 | ZymoGenetics, Inc. | Homogeneous preparations of IL-29 |
| AU2005266892B2 (en) * | 2004-07-29 | 2011-03-03 | Bristol-Myers Squibb Company | Use of IL-28 and IL-29 to treat cancer and autoimmune disorders |
| EP1912668A2 (en) * | 2005-07-20 | 2008-04-23 | ZymoGenetics, Inc. | Il28 and il29 truncated cysteine mutants and antiviral methods of using same |
| AU2006272937A1 (en) * | 2005-07-20 | 2007-02-01 | Bristol-Myers Squibb Company | Use of truncated cysteine IL28 and IL29 mutants to treat cancers and autoimmune disorders |
| EP1931704B1 (en) | 2005-10-04 | 2010-12-15 | ZymoGenetics, L.L.C. | Production and purification of il-29 |
| JP5784272B2 (ja) * | 2006-04-24 | 2015-09-24 | ジェネンテック, インコーポレイテッド | 自己免疫性疾患を検出するための方法及び組成物 |
| WO2009036510A1 (en) * | 2007-09-20 | 2009-03-26 | Commonwealth Scientific And Industrial Research Organisation | Novel avian cytokines and genetic sequences encoding same |
| US8354125B2 (en) | 2007-10-27 | 2013-01-15 | Grant Gallagher | Ex-vivo treatment of peripheral blood leukocytes with IFN-λ |
| AU2009231598B2 (en) | 2008-04-04 | 2015-03-12 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using IL-28 and compositions and methods of using the same |
| RU2496514C2 (ru) * | 2008-06-05 | 2013-10-27 | Займоджинетикс, Инк. | Применение пэгилированных интерферонов типа iii для лечения гепатита с |
| US20100316604A1 (en) * | 2009-04-21 | 2010-12-16 | Asterion Limited | Interferon lambda fusion polypeptides |
| US9532222B2 (en) | 2010-03-03 | 2016-12-27 | Duo Security, Inc. | System and method of notifying mobile devices to complete transactions after additional agent verification |
| US9544143B2 (en) | 2010-03-03 | 2017-01-10 | Duo Security, Inc. | System and method of notifying mobile devices to complete transactions |
| JP5821198B2 (ja) * | 2011-01-27 | 2015-11-24 | 富士レビオ株式会社 | 抗il28b抗体及びこれを用いたil28bの測定方法 |
| WO2013029062A1 (en) * | 2011-08-25 | 2013-02-28 | Nanogen Pharmaceutical Biotechnology Co., Ltd | Peginterferon lambda 1 conjugates, processes for their preparation, pharmaceutical compositions containing these conjugates and processes for making the same |
| US9467463B2 (en) | 2011-09-02 | 2016-10-11 | Duo Security, Inc. | System and method for assessing vulnerability of a mobile device |
| EP2922870B1 (en) * | 2012-11-21 | 2019-08-07 | The Governors of the University of Alberta | Immunomodulatory peptides and methods of use thereof |
| CN103898123B (zh) * | 2012-12-28 | 2019-03-15 | 北京韩美药品有限公司 | 重组人IFN-β-1a及其生产和纯化方法 |
| EP3954714A1 (en) | 2014-01-08 | 2022-02-16 | Prosit Sole Biotechnology (Beijing) Co. Ltd | Fusion polypeptides and methods of use |
| US9930060B2 (en) | 2015-06-01 | 2018-03-27 | Duo Security, Inc. | Method for enforcing endpoint health standards |
| AU2018261750A1 (en) * | 2017-05-01 | 2019-11-14 | Rutgers, The State University Of New Jersey | Type I and type III interferon fusion molecules and methods for use thereof |
| US10412113B2 (en) | 2017-12-08 | 2019-09-10 | Duo Security, Inc. | Systems and methods for intelligently configuring computer security |
| US11658962B2 (en) | 2018-12-07 | 2023-05-23 | Cisco Technology, Inc. | Systems and methods of push-based verification of a transaction |
| US20220378878A1 (en) * | 2019-12-20 | 2022-12-01 | The Council Of The Queensland Institute Of Medical Research | Treatment of gastrointestinal disease |
| CN112694526B (zh) * | 2020-05-27 | 2023-01-20 | 杭州先为达生物科技有限公司 | 一种白细胞介素29突变体蛋白 |
| CN112870336B (zh) * | 2021-02-24 | 2022-06-14 | 杭州先为达生物科技有限公司 | 一种白细胞介素29突变体蛋白制剂 |
| CN115252764A (zh) * | 2022-08-09 | 2022-11-01 | 南方医科大学 | 一种白介素在制备治疗急性髓系白血病的药物中的应用 |
Citations (4)
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| WO2002086087A2 (en) * | 2001-04-20 | 2002-10-31 | Zymogenetics, Inc. | Cytokine protein family |
| WO2002092762A2 (en) * | 2001-05-10 | 2002-11-21 | Immunex Corporation | Cytokine polypeptides |
| WO2003066002A2 (en) * | 2002-02-08 | 2003-08-14 | University Of Medicine And Dentistry Of New Jersey | IFN-a/b-INDEPENDENT MECHANISM OF ANTIVIRAL PROTECTION |
| WO2004037995A2 (en) * | 2002-10-23 | 2004-05-06 | Zymogenetics, Inc. | Methods for treating viral infection using il-28 and il-29 |
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- 2005-07-29 EP EP05797809A patent/EP1793845A2/en not_active Withdrawn
- 2005-07-29 CN CN2010101140769A patent/CN101829318B/zh not_active Expired - Lifetime
- 2005-07-29 CA CA2574564A patent/CA2574564C/en not_active Expired - Lifetime
- 2005-07-29 US US11/193,955 patent/US7351689B2/en not_active Expired - Lifetime
- 2005-07-29 WO PCT/US2005/026951 patent/WO2006012644A2/en not_active Ceased
- 2005-07-29 JP JP2007523839A patent/JP2008508310A/ja active Pending
- 2005-07-29 EP EP11157360A patent/EP2389944A1/en not_active Withdrawn
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2007
- 2007-01-08 IL IL180589A patent/IL180589A0/en unknown
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2008
- 2008-02-12 US US12/030,107 patent/US7786075B2/en active Active
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2010
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| US7351689B2 (en) | 2008-04-01 |
| CA2574564C (en) | 2013-04-16 |
| JP2008508310A (ja) | 2008-03-21 |
| US20060024269A1 (en) | 2006-02-02 |
| EP2389944A1 (en) | 2011-11-30 |
| EP1793845A2 (en) | 2007-06-13 |
| WO2006012644A2 (en) | 2006-02-02 |
| US20100291030A1 (en) | 2010-11-18 |
| AU2005266892A1 (en) | 2006-02-02 |
| US20080167244A1 (en) | 2008-07-10 |
| WO2006012644A3 (en) | 2007-02-01 |
| US8361954B2 (en) | 2013-01-29 |
| IL180589A0 (en) | 2007-06-03 |
| BRPI0513865A (pt) | 2008-05-20 |
| AU2005266892B2 (en) | 2011-03-03 |
| CA2574564A1 (en) | 2006-02-02 |
| US7786075B2 (en) | 2010-08-31 |
| CN101829318A (zh) | 2010-09-15 |
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